L. Qian

发表

CRTH2 promotes endoplasmic reticulum stress‐induced cardiomyocyte apoptosis through m‐calpain

Yujun Shen, Ying Yu, Juan Tang, 2018, EMBO molecular medicine.

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin‐induced damage

R. Lu, Q. Wang, Dan Zhang, 2012, British journal of pharmacology.

Neuroinflammation is a key player in Parkinson’s disease and a prime target for therapy

Jau-Shyong Hong, L. Qian, P. Flood, 2010, Journal of Neural Transmission.

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity

Xiaoming Hu, Sung-Jen Wei, Dan Zhang, 2008, Journal of Neuroinflammation.

Isoflurane preconditioning protects against ischemia-reperfusion injury partly by attenuating cytochrome c release from subsarcolemmal mitochondria in isolated rat hearts

Jun-Li Cao, L. Qian, Yin-ming Zeng, 2005, Acta Pharmacologica Sinica.

β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway

R. Lu, Syed F. Ali, Dan Zhang, 2011, The Journal of Immunology.

β2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK‐dependent/protein kinase A‐independent pathway

R. Lu, Xiaoming Hu, Dan Zhang, 2009, Glia.

Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases

Qingshan Wang, Shih-Heng Chen, E. Oyarzabal, 2014, Glia.

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity

Xiaoming Hu, Dan Zhang, Shih-Heng Chen, 2011, Journal of Neuroinflammation.

Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease

Jau-Shyong Hong, L. Qian, F. Zhang, 2011, Parkinson's disease.

Formyl-methionyl-leucyl-phenylalanine–Induced Dopaminergic Neurotoxicity via Microglial Activation: A Mediator between Peripheral Infection and Neurodegeneration?

Sufen Yang, M. Block, Xiaoming Hu, 2008, Environmental health perspectives.

Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits.

A. Granholm, F. Crews, Jau-Shyong Hong, 2008, Neurotoxicology.

Potent Anti-Inflammatory and Neuroprotective Effects of TGF-β1 Are Mediated through the Inhibition of ERK and p47phox-Ser345 Phosphorylation and Translocation in Microglia1

Xiaoming Hu, Sung-Jen Wei, Dan Zhang, 2008, The Journal of Immunology.

Journal of Neuroinflammation Sinomenine, a Natural Dextrorotatory Morphinan Analog, Is Anti-inflammatory and Neuroprotective through Inhibition of Microglial Nadph Oxidase

Jau-Shyong Hong, B. Wilson, Zongli Xu, 2007 .

Microglia-Mediated Neurotoxicity Is Inhibited by Morphine through an Opioid Receptor-Independent Reduction of NADPH Oxidase Activity1

Sung-Jen Wei, Jau-Shyong Hong, B. Wilson, 2007, The Journal of Immunology.

Oxidase Activity Receptor-Independent Reduction of NADPH Inhibited by Morphine through an Opioid Microglia-Mediated Neurotoxicity

Sung-Jen Wei, B. Wilson, Zongli Xu, 2007 .

MAC1 mediates LPS‐induced production of superoxide by microglia: The role of pattern recognition receptors in dopaminergic neurotoxicity

Sufen Yang, M. Block, Z. Pei, 2007, Glia.

Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro.

Xiaoming Hu, R. Langenbach, Dan Zhang, 2009, Toxicology and applied pharmacology.

Synthesis and Protective Effect of Scutellarein on Focal Cerebral Ischemia/Reperfusion in Rats

Yuping Tang, Nianguang Li, Li Zhang, 2012, Molecules.

NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation.

M. Block, Z. Pei, Jau-Shyong Hong, 2007, Parkinsonism & related disorders.

Verapamil protects dopaminergic neuron damage through a novel anti-inflammatory mechanism by inhibition of microglial activation

F. Crews, Y. Lo, R. Lu, 2011, Neuropharmacology.

Interleukin-10 Protects Lipopolysaccharide-Induced Neurotoxicity in Primary Midbrain Cultures by Inhibiting the Function of NADPH Oxidase

M. Block, Chiou-Feng Lin, Sung-Jen Wei, 2006, Journal of Pharmacology and Experimental Therapeutics.

Role of microglia in inflammation-mediated degeneration of dopaminergic neurons: neuroprotective effect of interleukin 10.

Jau-Shyong Hong, L. Qian, P. Flood, 2006, Journal of neural transmission. Supplementum.

Glycogen synthase kinase‐3 negatively regulates anti‐inflammatory interleukin‐10 for lipopolysaccharide‐induced iNOS/NO biosynthesis and RANTES production in microglial cells

Yee‐Shin Lin, P. Lu, P. Chen, 2009, Immunology.

The role of titanium surface topography on J774A.1 macrophage inflammatory cytokines and nitric oxide production.

Patrick M Flood, Lyndon F Cooper, L. Cooper, 2006, Biomaterials.

Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models.

Syed F. Ali, Qingshan Wang, Shih-Heng Chen, 2015, Brain : a journal of neurology.

Substance P enhances microglial density in the substantia nigra through neurokinin-1 receptor/NADPH oxidase-mediated chemotaxis in mice.

Qingshan Wang, E. Oyarzabal, Jau-Shyong Hong, 2015, Clinical science.

Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase

Sean L. Wentworth, L. Diatchenko, A. Nackley, 2009, Molecular pain.

Astrogliosis in CNS Pathologies: Is There A Role for Microglia?

J. O'Callaghan, Xiaoming Hu, Dan Zhang, 2010, Molecular Neurobiology.

Inhibition of IκB Kinase-β Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity

Jau-Shyong Hong, L. Qian, Hui-Ming Gao, 2010, Journal of Pharmacology and Experimental Therapeutics.

Microglial cells and Parkinson’s disease

L. Qian, P. Flood, 2008, Immunologic research.

Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation

Hung-Ming Wu, Ru-Band Lu, R. Lu, 2009, Neuropsychopharmacology.

Clozapine Protects Dopaminergic Neurons from Inflammation-Induced Damage by Inhibiting Microglial Overactivation

Sufen Yang, P. Chen, R. Lu, 2011, Journal of Neuroimmune Pharmacology.

Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase

Hyoung‐Chun Kim, Syed F. Ali, Qingshan Wang, 2014, The Journal of Neuroscience.

Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson’s Disease1

D. D. Di Monte, Jing Zhang, M. Block, 2008, The Journal of Immunology.

Clozapine Protects Dopaminergic Neurons from Inflammation-Induced Damage by Inhibiting Microglial Overactivation

Sufen Yang, P. Chen, R. Lu, 2012, Journal of Neuroimmune Pharmacology.

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase

Jau-Shyong Hong, B. Wilson, Zongli Xu, 2007, Journal of Neuroinflammation.

MPTP Model of Parkinson's Disease Dopaminergic Neurodegeneration in the Reactive Microgliosis and Progressive Macrophage Antigen Complex-1 Mediates

Belinda, Wilson, Jing Zhang, 2008 .