Yuanyuan Zhang

发表

Ruscogenin alleviates LPS-triggered pulmonary endothelial barrier dysfunction through targeting NMMHC IIA to modulate TLR4 signaling

J. Kou, Yunhao Wu, Xiu Yu, 2021, Acta pharmaceutica Sinica. B.

Inhibition of myosin IIA-actin interaction prevents ischemia/reperfusion induced cardiomyocytes apoptosis through modulating PINK1/Parkin pathway and mitochondrial fission.

J. Kou, Fang Li, Yuanyuan Zhang, 2018, International journal of cardiology.

NMMHC IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signalling pathways in the endothelium

Yan Wang, J. Kou, Yan Wang, 2015, Thrombosis and Haemostasis.

Tetrahydroberberrubine attenuates lipopolysaccharide-induced acute lung injury by down-regulating MAPK, AKT, and NF-κB signaling pathways.

Han Liu, Ling Chen, J. Kou, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Ophiopogonin-D suppresses MDA-MB-435 cell adhesion and invasion by inhibiting matrix metalloproteinase-9.

Jihua Liu, J. Kou, Boyang Yu, 2015, Molecular medicine reports.

DT-13 suppresses MDA-MB-435 cell adhesion and invasion by inhibiting MMP-2/9 via the p38 MAPK pathway.

Jihua Liu, J. Kou, Boyang Yu, 2012, Molecular medicine reports.

DT-13, a steroidal saponin from Liriope muscari L. H. Bailey, suppresses A549 cells adhesion and invasion by inhibiting MMP-2/9

J. Kou, Ji-Hua Liu, Yuanyuan Zhang, 2012 .

YiQiFuMai lyophilized injection attenuates cerebral ischemic injury with inhibition of neuronal autophagy through intervention in the NMMHC IIA-actin-ATG9A interaction.

J. Kou, Shuaishuai Gong, Fang Li, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Yan Wang, J. Kou, Boyang Yu, 2017, Front. Mol. Neurosci..

YiQiFuMai powder injection ameliorates chronic heart failure through cross-talk between adipose tissue and cardiomyocytes via up-regulation of circulating adipokine omentin.

J. Kou, Fang Li, Boyang Yu, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-κB and ROCK1/MLC signaling pathways.

J. Kou, Fang Li, Yuanyuan Zhang, 2016, Journal of ethnopharmacology.

Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1

Le Shen, J. Kou, Fang Li, 2021, Basic Research in Cardiology.

Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK

J. Kou, Yuanyuan Zhang, Bao-lin Liu, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

Ginsenoside Rb1 Improves Brain, Lung, and Intestinal Barrier Damage in Middle Cerebral Artery Occlusion/Reperfusion (MCAO/R) Mice Through the PPARγ Signaling Pathway

J. Kou, Fang Li, Yuanyuan Zhang, 2021 .

DT-13 Ameliorates TNF-α-Induced Vascular Endothelial Hyperpermeability via Non-Muscle Myosin IIA and the Src/PI3K/Akt Signaling Pathway

J. Kou, Boyang Yu, Yuanyuan Zhang, 2017, Front. Immunol..

Ruscogenin Alleviates Intestinal Bleeding and Blood Flow Induced by Dasatinib through ROCK/MLC Pathway

J. Kou, Fang Li, Boyang Yu, 2020 .

YQFM Alleviates Side Effects Caused by Dasatinib through the ROCK/MLC Pathway in Mice

J. Kou, Han Xu, Fang Li, 2020, Evidence-based complementary and alternative medicine : eCAM.

Ophiopogon Saponin C1 Inhibits Lung Tumors by Stabilizing Endothelium Permeability via Inhibition of PKCδ

J. Kou, Fang Li, Boyang Yu, 2020, International journal of biological sciences.

YiQiFuMai Lyophilized Injection Attenuates Sepsis-Induced Acute Lung Injury via TLR4/Src/VE-cadherin/p120-catenin Signaling Pathway

J. Kou, Fang Li, Yuanyuan Zhang, 2020 .

Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway

J. Kou, Boyang Yu, Yuanyuan Zhang, 2016, International journal of molecular sciences.

Ginsenoside Rg1 Protects against Oxidative Stress-induced Neuronal Apoptosis through Myosin IIA-actin Related Cytoskeletal Reorganization

Yan Wang, Jing-Rong Wang, J. Kou, 2016, International journal of biological sciences.

The myosin II inhibitor, blebbistatin, ameliorates pulmonary endothelial barrier dysfunction in acute lung injury induced by LPS via NMMHC IIA/Wnt5a/β-catenin pathway

J. Kou, Jiahui Tang, Fang Li, 2022, Toxicology and applied pharmacology.

Schisandrol A Attenuates Myocardial Ischemia/Reperfusion-Induced Myocardial Apoptosis through Upregulation of 14-3-3θ

J. Kou, Fang Li, Yuanyuan Zhang, 2021, Oxidative medicine and cellular longevity.

YiQiFuMai Powder Injection Protects against Ischemic Stroke via Inhibiting Neuronal Apoptosis and PKCδ/Drp1-Mediated Excessive Mitochondrial Fission

Yan Wang, J. Kou, Boyang Yu, 2017, Oxidative medicine and cellular longevity.

Schizandrin Protects against OGD/R-Induced Neuronal Injury by Suppressing Autophagy: Involvement of the AMPK/mTOR Pathway

J. Kou, Fang Li, Yuanyuan Zhang, 2019, Molecules.

YiQiFuMai Powder Injection Ameliorates Cerebral Ischemia by Inhibiting Endoplasmic Reticulum Stress-Mediated Neuronal Apoptosis

J. Kou, Boyang Yu, Yuanyuan Zhang, 2016, Oxidative medicine and cellular longevity.

DT-13 ameliorates TNF-α-induced nitric oxide production in the endothelium in vivo and in vitro.

J. Kou, Boyang Yu, Yuanyuan Zhang, 2018, Biochemical and biophysical research communications.

YiQiFuMai Lyophilized Injection ameliorates tPA-Induced hemorrhagic transformation by inhibiting cytoskeletal rearrangement associated with ROCK1 and NF-κB signaling pathways.

Yan Wang, J. Kou, Fang Li, 2020, Journal of ethnopharmacology.

The protective effects of Thalictrum minus L. on lipopolysaccharide-induced acute lung injury.

J. Kou, Yunhao Wu, Fang Li, 2020, Journal of ethnopharmacology.

Metabolomic Profiling of Brain Protective Effect of Edaravone on Cerebral Ischemia-Reperfusion Injury in Mice

J. Kou, Fang Li, Yuanyuan Zhang, 2021, Frontiers in Pharmacology.

The saponin D39 blocks dissociation of non‐muscular myosin heavy chain IIA from TNF receptor 2, suppressing tissue factor expression and venous thrombosis

J. Kou, Fang Li, Boyang Yu, 2017, British journal of pharmacology.

Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling.

J. Kou, Yunhao Wu, Yuwei Wang, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The saponin DT-13 Attenuates Tumor Necrosis Factor-α-induced Vascular Inflammation Associated with Src/NF-кB/MAPK Pathway Modulation

J. Kou, Boyang Yu, Yuanyuan Zhang, 2015, International journal of biological sciences.

NMMHC IIA triggers neuronal autophagic cell death by promoting F-actin-dependent ATG9A trafficking in cerebral ischemia/reperfusion

Yan Wang, Yang Sun, J. Kou, 2020, Cell Death & Disease.

NMMHC IIA Inhibition Ameliorates Cerebral Ischemic/Reperfusion-Induced Neuronal Apoptosis Through Caspase-3/ROCK1/MLC Pathway

J. Kou, Fang Li, Boyang Yu, 2020, Drug design, development and therapy.

An inhibitor of myosin II, blebbistatin, suppresses development of arterial thrombosis.

J. Kou, Boyang Yu, Yuanyuan Zhang, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The Myosin II Inhibitor, Blebbistatin, Ameliorates FeCl3-induced Arterial Thrombosis via the GSK3β-NF-κB Pathway

J. Kou, Boyang Yu, Yuanyuan Zhang, 2017, International journal of biological sciences.

YiQiFuMai lyophilized injection attenuates particulate matter-induced acute lung injury in mice via TLR4-mTOR-autophagy pathway.

J. Kou, Yuwei Wang, Jiahui Tang, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Ruscogenin attenuates sepsis-induced acute lung injury and pulmonary endothelial barrier dysfunction via TLR4/Src/p120-catenin/VE-cadherin signalling pathway.

J. Kou, Yunhao Wu, Yuwei Wang, 2021, The Journal of pharmacy and pharmacology.

Ruscogenin attenuates particulate matter-induced acute lung injury in mice via protecting pulmonary endothelial barrier and inhibiting TLR4 signaling pathway

J. Kou, Yunhao Wu, Yuwei Wang, 2020, Acta Pharmacologica Sinica.

NMMHC IIA triggers neuronal autophagic cell death by promoting F-actin-dependent ATG9A trafficking in cerebral ischemia/reperfusion

Yan Wang, Yang Sun, J. Kou, 2020, Cell Death & Disease.

The Traditional Chinese Medicine Compound, GRS, Alleviates Blood–Brain Barrier Dysfunction

J. Kou, Boyang Yu, Yuanyuan Zhang, 2020, Drug design, development and therapy.

Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury

J. Kou, Fang Li, Boyang Yu, 2021, Frontiers in Pharmacology.

Mechanisms Dissection of the combination GRS derived from ShengMai preparations for the treatment of myocardial ischemia/reperfusion injury.

J. Kou, Fang Li, Yuanyuan Zhang, 2020, Journal of ethnopharmacology.

Ruscogenin ameliorates dasatinib-induced intestinal barrier dysfunction via ErbB4/YAP and ROCK/MLC pathways

J. Kou, Fang Li, Yuanyuan Zhang, 2023, Journal of Natural Medicines.

Endothelial Conditional Knockdown of NMMHC IIA (Nonmuscle Myosin Heavy Chain IIA) Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury

J. Kou, Fang Li, Boyang Yu, 2021, Stroke.

Cocktail of Four Active Components Derived from Sheng Mai San Inhibits Hydrogen Peroxide-Induced PC12 Cell Apoptosis Linked with the Caspase-3/ROCK1/MLC Pathway.

Yan Wang, J. Kou, Boyang Yu, 2015, Rejuvenation research.

Cocktail of Four Active Components Derived from Sheng Mai San Inhibits Hydrogen Peroxide-Induced PC12 Cell Apoptosis Linked with the Caspase-3/ROCK1/MLC Pathway.

Yan Wang, J. Kou, Boyang Yu, 2015, Rejuvenation research.

NMMHC IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signalling pathways in the endothelium

J. Kou, Yan Wang, Fang Li, 2015, Thrombosis and Haemostasis.