W. Yang

发表

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

M. R. Lamprecht, B. Stockwell, S. Dixon, 2012, Cell.

Multivalent Small-Molecule Pan-RAS Inhibitors

Matthew E. Welsch, A. Ferrando, B. Stockwell, 2017, Cell.

Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest

Brent R Stockwell, Wan Seok Yang, B. Stockwell, 2008, Genome Biology.

Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency

B. Stockwell, R. Skouta, W. Yang, 2011, ACS medicinal chemistry letters.

Small molecule screen reveals regulation of survival motor neuron protein abundance by Ras proteins.

Mitchell R Lunn, Brent R Stockwell, Wan Seok Yang, 2013, ACS chemical biology.

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Jill P. Mesirov, Dong Gao, Stuart L. Schreiber, 2017, Nature.

Suicide cancer gene therapy using pore-forming toxin, streptolysin O

A. Yoon, C. Yun, C. Kim, 2006, Molecular Cancer Therapeutics.

Inhibition of poly(ADP‐ribose)polymerase binding to DNA by thymidine dimer

Jin Kim, Byong-Seok Choi, C. Joe, 1999, FEBS letters.

Detection of Ferroptosis by BODIPY™ 581/591 C11.

W. Yang, Alejandra M Martinez, Ahryun Kim, 2020, Methods in molecular biology.

Conversion of Bfl‐1, an anti‐apoptotic Bcl‐2 family protein, to a potent pro‐apoptotic protein by fusion with green fluorescent protein (GFP)

Yong‐Nyun Kim, C. Kim, W. Yang, 2003, FEBS letters.

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

B. Stockwell, M. Shchepinov, W. Yang, 2016, Proceedings of the National Academy of Sciences.

Ferroptosis: Death by Lipid Peroxidation.

B. Stockwell, W. Yang, 2016, Trends in cell biology.

Development of small-molecule probes that selectively kill cells induced to express mutant RAS.

Joshua A. Bittker, S. Schreiber, B. Stockwell, 2012, Bioorganic & medicinal chemistry letters.

RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels

B. Stockwell, S. Sahasrabudhe, J. Peltier, 2007, Nature.

Regulation of Ferroptotic Cancer Cell Death by GPX4

Matthew E. Welsch, P. Clemons, S. Schreiber, 2014, Cell.

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

B. Stockwell, W. Yang, 2008, Chemistry & biology.

Global Survey of Cell Death Mechanisms Reveals Metabolic Regulation of Ferroptosis

B. Stockwell, S. Dixon, R. Skouta, 2016, Nature chemical biology.

Negative Regulation of the Sapk/Jnk Signaling Pathway by Presenilin 1

R. Tanzi, I. Mook‐Jung, C. Joe, 2001, The Journal of cell biology.

Multivalent Small-Molecule Pan-RAS Inhibitors Graphical

Matthew E. Welsch, A. Ferrando, B. Stockwell, 2017 .

C‐terminal region of Bfl‐1 induces cell death that accompanies caspase activation when fused with GFP

Yong‐Nyun Kim, C. Kim, W. Yang, 2005, Journal of cellular biochemistry.

Protein Prenylation Constitutes an Endogenous Brake on Axonal Growth.

Derek H. Oakley, Mackenzie W. Mathis, H. Wichterle, 2016, Cell reports.

Protein Prenylation Const itutes an Endogenous Brake on Axonal Growth Graphical Abstract Highlights

Derek H. Oakley, Mackenzie W. Mathis, H. Wichterle, 2016 .

Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility.

B. Stockwell, W. Yang, B. Slusher, 2015, Bioorganic & medicinal chemistry letters.

Screen for RAS-Selective Lethal Compounds and VDAC Ligands - Probe 2

Joshua A. Bittker, S. Schreiber, B. Stockwell, 2011 .

NSC‐34 motor neuron‐like cells are sensitized to ferroptosis upon differentiation

W. Yang, Alejandra M Martinez, Jovan Mirkovic, 2019, FEBS open bio.

Key Figure Molecular Pathways of Ferroptosis Regulation . System

B. Stockwell, W. Yang, 2016 .

Novel Synthesis of Paricalcitol by Chem-biotransformation

W. Yang, Peng Wen, Pan Zhang, 2012 .

Mouse embryonic stem cell‐derived motor neurons are susceptible to ferroptosis

W. Yang, Cristina Flores, Alejandra M Martinez, 2023, FEBS open bio.

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

B. Stockwell, N. Pagano, W. Yang, 2015, Cell Death and Differentiation.

Ferroptosis: whERe is the critical site of lipid peroxidation?

W. Yang, 2023, Frontiers in Cell and Developmental Biology.