T. Souza

发表

Chemistry and anti-herpes simplex virus type 1 evaluation of 4-substituted-1H-1,2,3-triazole-nitroxyl-linked hybrids

Carolina Q. Sacramento, V. Ferreira, A. Cunha, 2020, Molecular Diversity.

The COVID-19 pandemics and the relevance of biosafety facilities for metagenomics surveillance, structured disease prevention and control

C. Morel, T. Souza, 2020, Biosafety and Health.

Inhibitory effect of microalgae and cyanobacteria extracts on influenza virus replication and neuraminidase activity

F. Thompson, C. Thompson, T. Souza, 2018, PeerJ.

Capturing diverse microbial sequence with comprehensive and scalable probe design

Hayden C. Metsky, David K. Yang, Todd M. Allen, 2018, bioRxiv.

H1N1pdm Influenza Infection in Hospitalized Cancer Patients: Clinical Evolution and Viral Analysis

F. Bozza, M. Soares, J. Salluh, 2010, PloS one.

SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil

J. Abrantes, T. Souza, S. Kuriyama, 2022, Frontiers in Medicine.

HIV-1 and Its gp120 Inhibits the Influenza A(H1N1)pdm09 Life Cycle in an IFITM3-Dependent Fashion

Carolina Q. Sacramento, C. Sacramento, J. Abrantes, 2014, PloS one.

Genome sequencing reveals Zika virus diversity and spread in the Americas

A. L. Tan, A. Gnirke, M. Halloran, 2017, bioRxiv.

Non-permissive SARS-CoV-2 infection in human neurospheres

Carolina Q. Sacramento, S. Rehen, P. Bozza, 2020, bioRxiv.

Atazanavir Is a Competitive Inhibitor of SARS-CoV-2 Mpro, Impairing Variants Replication In Vitro and In Vivo

Carolina Q. Sacramento, H. Castro-Faria-Neto, P. Bozza, 2021, bioRxiv.

Intranasal Immunization with Pressure Inactivated Avian Influenza Elicits Cellular and Humoral Responses in Mice

D. Ferreira, Jerson L. Silva, F. Bozza, 2015, PloS one.

Increased expression of MCPIP1 in HIV-1 controllers is correlated with overexpression of p21

V. Veloso, B. Grinsztejn, M. Ribeiro-Alves, 2019, bioRxiv.

Neuraminidase from Influenza A and B viruses is susceptible to the compound 4-(4-Phenyl-1H-1,2,3-Triazol-1-yl)-2,2,6,6-Tetramethylpiperidine-1-Oxyl.

V. Ferreira, A. Cunha, C. Sacramento, 2019, Current topics in medicinal chemistry.

Immunogenicity and sustainability of the immune response in Brazilian HIV‐1‐infected individuals vaccinated with inactivated triple influenza vaccine

L. Camacho, V. Veloso, B. Grinsztejn, 2016, Journal of medical virology.

Macrophages undergo necroptosis during severe influenza A infection and contribute to virus-associated cytokine storm

Carolina Q. Sacramento, F. Bozza, P. Bozza, 2022, bioRxiv.

Human endogenous retrovirus K in the respiratory tract is associated with COVID-19 physiopathology

Carolina Q. Sacramento, Huiting Jiang, S. Mandacaru, 2022, Microbiome.

Detection of the Influenza A(H1N1)pdm09 Virus Carrying the K-15E, P83S and Q293H Mutations in Patients Who Have Undergone Bone Marrow Transplant

C. Sacramento, J. Abrantes, T. Souza, 2014, PloS one.

Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19

Carolina Q. Sacramento, C. Righy, F. Bozza, 2022, Blood Advances.

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

C. Righy, F. Bozza, P. Bozza, 2020, Blood.

2,8-bis(trifluoromethyl)quinoline analogs show improved anti-Zika virus activity, compared to mefloquine.

P. Bozza, G. Barbosa-Lima, T. Souza, 2017, European journal of medicinal chemistry.

Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae

Carolina Q. Sacramento, A. Tanuri, F. Bozza, 2017, Scientific Reports.

N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity.

P. Bozza, C. Kaiser, G. Barbosa-Lima, 2017, European journal of medicinal chemistry.

Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating

Carolina Q. Sacramento, S. Rehen, P. Bozza, 2021, PeerJ.

The Chemokine CCL5 Inhibits the Replication of Influenza A Virus Through SAMHD1 Modulation

V. C. Soares, S. S. G. Dias, T. Souza, 2021, Frontiers in Cellular and Infection Microbiology.

Polymorphisms at Residue 222 of the Hemagglutinin of Pandemic Influenza A(H1N1)pdm09: Association of Quasi-Species to Morbidity and Mortality in Different Risk Categories

T. Souza, M. Siqueira, T. S. Gregianini, 2014, PloS one.

Proteomic Profile of Procoagulant Extracellular Vesicles Reflects Complement System Activation and Platelet Hyperreactivity of Patients with Severe COVID-19

S. Mandacaru, F. Bozza, H. Castro-Faria-Neto, 2022, Frontiers in Cellular and Infection Microbiology.

Platelet proteome reveals features of cell death, antiviral response and viral replication in covid-19

Marlon D. M. Santos, S. Mandacaru, F. Bozza, 2022, Cell death discovery.

Human endogenous retrovirus K activation in the lower respiratory tract of severe COVID-19 patients associates with early mortality

Carolina Q. Sacramento, Huiyan Jiang, S. Mandacaru, 2021 .

COVID-19 hospital admissions: Brazil's first and second waves compared

S. Hamacher, F. Bozza, T. Souza, 2021, The Lancet Respiratory Medicine.

Computational and Experimental Approaches Identify Beta-Blockers as Potential SARS-CoV-2 Spike Inhibitors

S. Ekins, C. Andrade, K. Pearce, 2022, ACS omega.

Fluorine Atoms on C6H5-Corrole Affect the Interaction with Mpro and PLpro Proteases of SARS-CoV-2: Molecular Docking and 2D-QSAR Approaches

Carolina Q. Sacramento, H. Castro-Faria-Neto, C. Sacramento, 2022, International journal of molecular sciences.

The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages.

T. Souza, J. Temerozo, D. Bou-Habib, 2011, Blood.

Influenza virus RNA polymerase may be activated inside the virion.

C. Sacramento, T. Souza, M. Siqueira, 2018, The Journal of general virology.

Agathisflavone, a natural biflavonoid that inhibits SARS-CoV-2 replication by targeting its proteases

Carolina Q. Sacramento, N. Carels, H. Castro-Faria-Neto, 2022, International Journal of Biological Macromolecules.

Agathisflavone, a biflavonoid from Anacardium occidentale L., inhibits influenza virus' neuraminidase.

P. Bozza, S. P. C. Barroso, A. C. de Oliveira, 2019, Current topics in medicinal chemistry.

Clinical Manifestations of Zika Virus Infection, Rio de Janeiro, Brazil, 2015

F. Bozza, T. Souza, S. Sampaio, 2016, Emerging infectious diseases.

Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).

M. Sola-Penna, Jéssica Costa, T. Souza, 2012, Biochimica et biophysica acta.

Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs

O. Santos-Filho, V. Ferreira, C. Sacramento, 2013, Medicinal Chemistry Research.

Sofosbuvir shows a protective effect against vertical transmission of Zika virus and the associated congenital syndrome in rhesus monkeys.

R. Marchevsky, A. M. Alves, S. Lima, 2020, Antiviral research.

Implemented occupational health surveillance limits the spread of SARS-CoV-2 Omicron at the workplace

T. Souza, S. Kuriyama, A. Cabanelas, 2022, Frontiers in Medicine.

Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil

J. Drexler, C. Drosten, F. Bozza, 2019, Emerging Infectious Diseases.

Molecular findings from influenza A(H1N1)pdm09 detected in patients from a Brazilian equatorial region during the pandemic period

T. Souza, M. Siqueira, W. A. de Mello, 2014, Memorias do Instituto Oswaldo Cruz.

Molecular findings from influenza A(H1N1)pdm09 detected in patients from a Brazilian equatorial region during the pandemic period.

T. Souza, M. Siqueira, P. Resende, 2014, Memorias do Instituto Oswaldo Cruz.

Detection of Oseltamivir-Resistant Pandemic Influenza A(H1N1)pdm2009 in Brazil: Can Community Transmission Be Ruled Out?

N. Ikuta, T. Souza, M. Siqueira, 2013, PloS one.

The clinically approved antiviral drug sofosbuvir impairs brazilian zika virus replication

Carolina Q. Sacramento, F. Thompson, F. Bozza, 2016, bioRxiv.

Commercially Available Flavonols Are Better SARS-CoV-2 Inhibitors than Isoflavone and Flavones

Carolina Q. Sacramento, J. Ju, J. Russo, 2022, Viruses.

Apixaban, an orally available anticoagulant, inhibits SARS-CoV-2 replication and its major protease in a non-competitive way

H. Castro-Faria-Neto, P. Bozza, Filipe S. Pereira-Dutra, 2022, Journal of molecular cell biology.

Emergence of the East-Central-South-African genotype of Chikungunya virus in Brazil and the city of Rio de Janeiro may have occurred years before surveillance detection

Riddhi Thakkar, Giselle Barbosa-Lima, Fernando A Bozza, 2018, Scientific Reports.

The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 In Vitro Replicative Cycle

V. C. Soares, T. Souza, Carlos Frederico Leite Fontes, 2022, International journal of molecular sciences.

Preclinical development of kinetin as a safe error-prone SARS-CoV-2 antiviral able to attenuate virus-induced inflammation

Carolina Q. Sacramento, Pedro P. G. Guimarães, Patrícia B Momo, 2023, Nature Communications.

Design, synthesis, and biological evaluation of new 3-hydroxy-2-oxo-3-trifluoromethylindole as potential HIV-1 reverse transcriptase inhibitors

N. Romeiro, I. Frugulhetti, T. Souza, 2007, Medicinal Chemistry Research.

The alkaloid 4-methylaaptamine isolated from the sponge Aaptos aaptos impairs Herpes simplex virus type 1 penetration and immediate-early protein synthesis.

T. Souza, I. Frugulhetti, J. L. Abrantes, 2007, Planta medica.

Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives.

H. Castro, C. R. Rodrigues, Cláudio Cirne-Santos, 2009, Bioorganic & medicinal chemistry.

Inhibition of HSV-1 replication and HSV DNA polymerase by the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid and its aglycone.

V. Ferreira, T. Souza, Carlos Frederico Leite Fontes, 2008, Antiviral research.

Non-permissive SARS-CoV-2 infection in human neurospheres

S. Rehen, P. Bozza, V. C. Soares, 2020, bioRxiv.

Oseltamivir-resistant influenza A(H1N1)pdm2009 strains found in Brazil are endowed with permissive mutations, which compensate the loss of fitness imposed by antiviral resistance

F. Bozza, T. Souza, M. Siqueira, 2015, Memorias do Instituto Oswaldo Cruz.

Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture

Carolina Q. Sacramento, T. Tuschl, D. Patel, 2022, Communications biology.

In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19

Carolina Q. Sacramento, T. Tuschl, D. Patel, 2021, The Journal of antimicrobial chemotherapy.

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

Carolina Q. Sacramento, S. Ekins, R. Baric, 2021, ACS omega.

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

Carolina Q. Sacramento, S. Ekins, R. Baric, 2020, bioRxiv.

Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production

Carolina Q. Sacramento, N. Carels, F. Bozza, 2020, Antimicrobial Agents and Chemotherapy.

Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production

Carolina Q. Sacramento, N. Carels, F. Bozza, 2020, bioRxiv.

Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication

S. Rehen, F. Bozza, P. Bozza, 2018, Antimicrobial Agents and Chemotherapy.

Genome sequencing reveals Zika virus diversity and spread in the Americas

Karthik Gangavarapu, Hayden C. Metsky, Catherine A. Freije, 2017, bioRxiv.

SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites

Carolina Q. Sacramento, N. Carels, S. De-Simone, 2021, International journal of molecular sciences.

New Efavirenz Derivatives and 1,2,3-Triazolyl-phosphonates as Inhibitors of Reverse Transcriptase of HIV-1.

T. Souza, N. Boechat, M. Bastos, 2018, Current topics in medicinal chemistry.

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

Carolina Q. Sacramento, F. Thompson, S. Rehen, 2017, Scientific Reports.

H1N1pdm09 Adjuvanted Vaccination in HIV-Infected Adults: A Randomized Trial of Two Single versus Two Double Doses

L. Camacho, V. Veloso, B. Grinsztejn, 2012, PloS one.

The dolabellane diterpene Dolabelladienetriol is a typical noncompetitive inhibitor of HIV-1 reverse transcriptase enzyme.

A. Tanuri, Cláudio Cirne-Santos, T. Souza, 2008, Antiviral research.

Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum

A. Tanuri, Jerson L. Silva, A. M. Gomes, 2021, bioRxiv.

Differential haplotype expression in class I MHC genes during SARS-CoV-2 infection of human lung cell lines

A. R. D. de Vasconcelos, T. Souza, J. Temerozo, 2022, bioRxiv.

Genetic Evidence and Host Immune Response in Persons Reinfected with SARS-CoV-2, Brazil

F. Bozza, P. Bozza, Hui Jiang, 2021, Emerging infectious diseases.

Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells

Carolina Q. Sacramento, Alberto Paccanaro, P. Bozza, 2021, bioRxiv.

SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

Carolina Q. Sacramento, F. Bozza, P. Bozza, 2021, Cell death discovery.

A Biosafety Level 2 Mouse Model for Studying Betacoronavirus-Induced Acute Lung Damage and Systemic Manifestations

C. Guatimosim, L. P. de Sousa, Clarice Weis Arns, 2021, Journal of virology.

The Effects of Neurotrophins and the Neuropeptides VIP and PACAP on HIV-1 Infection: Histories with Opposite Ends

T. Souza, J. Temerozo, D. Bou-Habib, 2014, Neuroimmunomodulation.

Correction: Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin

Carolina Q. Sacramento, O. Santos-Filho, C. Kaiser, 2015, PloS one.

Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin

Carolina Q. Sacramento, O. Santos-Filho, C. Kaiser, 2015, PloS one.

Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum

Daniel Olson, Salim Mattar, Kimberly Hamad-Schifferli, 2017, Science Translational Medicine.

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

Carolina Q. Sacramento, A. Tanuri, M. Teixeira, 2019, PLoS neglected tropical diseases.

Emergence of the East-Central-South-African genotype of Chikungunya virus in Brazil and the city of Rio de Janeiro may have occurred years before surveillance detection

F. Thompson, R. Nogueira, W. Lipkin, 2018, bioRxiv.

Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

Douglas S Kwon, David K. Yang, Todd M. Allen, 2019, Nature Biotechnology.

Severe influenza infection is associated with inflammatory programmed cell death in infected macrophages

Carolina Q. Sacramento, F. Bozza, P. Bozza, 2023, Frontiers in Cellular and Infection Microbiology.

Development of standard methods for Zika virus propagation, titration, and purification.

F. Thompson, L. B. de Arruda, F. A. Carneiro, 2017, Journal of virological methods.

The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle

L. Giaquinto, P. Bozza, R. Polishchuk, 2022, Nature.

HIV controllers suppress viral replication and evolution and prevent disease progression following intersubtype HIV-1 superinfection

V. Veloso, B. Grinsztejn, T. Souza, 2019, AIDS.

Polyclonal F(ab’)2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency

Carolina Q. Sacramento, A. Tanuri, Jerson L. Silva, 2021, iScience.

Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility

Carolina Q. Sacramento, S. Rehen, P. Bozza, 2021, bioRxiv.

1,2,3-Triazolyl-4-oxoquinolines: A feasible beginning for promising chemical structures to inhibit oseltamivir-resistant influenza A and B viruses.

O. Santos-Filho, V. Ferreira, A. Cunha, 2015, Bioorganic & medicinal chemistry.

VIP plasma levels associate with survival in severe COVID‐19 patients, correlating with protective effects in SARS‐CoV‐2‐infected cells

F. Bozza, P. Bozza, V. C. Soares, 2022, Journal of leukocyte biology.

Protective effects of VIP and PACAP in SARS-CoV-2 infection

Carolina Q. Sacramento, F. Bozza, P. Bozza, 2021 .

The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocytes and lung epithelial cells and decrease the production of proinflammatory cytokines in infected cells

Carolina Q. Sacramento, F. Bozza, P. Bozza, 2020 .

Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs

O. Santos-Filho, V. Ferreira, C. Sacramento, 2014, Medicinal Chemistry Research.

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

Carolina Q. Sacramento, F. Bozza, P. Bozza, 2020, bioRxiv.

Platelet proteome reveals features of cell death, antiviral response and viral replication in covid-19

Marlon D. M. Santos, S. Mandacaru, F. Bozza, 2022, Cell Death Discovery.

Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae

Carolina Q. Sacramento, A. Tanuri, F. Bozza, 2017, Scientific Reports.

Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts

Carolina Q. Sacramento, J. Viola, F. Bozza, 2022, Frontiers in Immunology.

WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2

Carolina Q. Sacramento, S. Rehen, P. Bozza, 2021, bioRxiv.

Promising novel compounds for the generation of new anti-HIV-RT therapeutic drugs

T. Souza, Carlos Frederico Leite Fontes, 2009 .

A cannabinoid receptor agonist shows anti-inflammatory and survival properties in human SARS-CoV-2-infected iPSC-derived cardiomyocytes

Carolina Q. Sacramento, S. Rehen, P. Bozza, 2021 .

Potent neutralizing equine antibodies raised against recombinant SARS-CoV-2 spike protein for COVID-19 passive immunization therapy

Carolina Q. Sacramento, A. Tanuri, Jerson L. Silva, 2020, bioRxiv.

Equine hyperimmune globulin raised against the SARS-CoV-2 spike glycoprotein has extremely high neutralizing titers

Carolina Q. Sacramento, A. Tanuri, Jerson L. Silva, 2020 .

Dengue virus‐activated platelets modulate monocyte immunometabolic response through lipid droplet biogenesis and cytokine signaling

G. Zimmerman, F. Bozza, P. Bozza, 2020, Journal of leukocyte biology.

Combination of Antiviral Drugs to Inhibit SARS-CoV-2 Polymerase and Exonuclease as Potential COVID-19 Therapeutics

Carolina Q. Sacramento, T. Tuschl, D. Patel, 2021, bioRxiv.

Apixaban, an orally available anticoagulant, inhibits SARS-CoV-2 replication by targeting its major protease in a non-competitive way

Carolina Q. Sacramento, H. Castro-Faria-Neto, P. Bozza, 2021, bioRxiv.

Design, synthesis, in vitro and in silico studies of novel 4-oxoquinoline ribonucleoside derivatives as HIV-1 reverse transcriptase inhibitors.

H. Castro, C. R. Rodrigues, T. Souza, 2020, European journal of medicinal chemistry.

SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

F. Bozza, P. Bozza, V. C. Soares, 2021, Cell Death Discovery.

New simplex Type 1 lytic infection pyridine system derivative as a novel goal against Herpes

Cláudio Cirne-Santos, Caroline Barros, I. Paixão, 2017 .

Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

David K. Yang, Todd M. Allen, A. L. Tan, 2019, Nature Biotechnology.

The in vitro antiviral activity of the anti-hepatitis C virus (HCV) drugs daclatasvir and sofosbuvir against SARS-CoV-2

Carolina Q. Sacramento, S. Rehen, F. Bozza, 2020, bioRxiv.

A suitable murine model for studying respiratory coronavirus infection and therapeutic countermeasures in BSL-2 laboratories

C. Guatimosim, L. P. de Sousa, M. Teixeira, 2021, bioRxiv.

VIP plasma levels associate with survival in severe COVID‐19 patients, correlating with protective effects in SARS‐CoV‐2‐infected cells

Carolina Q. Sacramento, F. Bozza, P. Bozza, 2020, bioRxiv.

Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1

Hugo Naya, L. Spangenberg, V. Veloso, 2020, Retrovirology.

Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX – REVOLUTIOn trial

Á. Avezum, R. Lopes, F. Machado, 2023, The Lancet Regional Health - Americas.

Multiepitope Proteins for the Differential Detection of IgG Antibodies against RBD of the Spike Protein and Non-RBD Regions of SARS-CoV-2

S. De-Simone, Paloma Napoleão-Pêgo, D. Provance, 2021, Vaccines.

The compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid inhibits HIV-1 replication by targeting the enzyme reverse transcriptase.

A. Tanuri, Cláudio Cirne-Santos, V. Ferreira, 2008, Current HIV research.