Bryony Graham

Genetic dissection of the α-globin super-enhancer in vivo

L. Pennacchio, J. Telenius, J. Hughes, 2016, Nature Genetics.

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions

J. Telenius, J. Hughes, D. Higgs, 2017, Nature Communications.

Enhancers predominantly regulate gene expression during differentiation via transcription initiation.

R. Schwessinger, D. Downes, J. Hughes, 2021, Molecular cell.

Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs

Monika S. Kowalczyk, C. Ponting, A. C. Marques, 2013, Genome Biology.

DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease

E. Li, J. Hughes, D. Higgs, 2017, Proceedings of the National Academy of Sciences.

MicroRNAs of the miR-290–295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

M. Mann, N. Brockdorff, A. Fisher, 2016, Stem cell reports.

Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells

Caleb Webber, Matthias Merkenschlager, Allison Piovesan, 2015, Genome research.

The worm has turned

J. Hughes, D. Higgs, Deborah Hay, 2014, BioEssays : news and reviews in molecular, cellular and developmental biology.

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions

J. Hughes, D. Higgs, N. Roberts, 2017, bioRxiv.

Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription

L. Game, M. Sacristán, D. Eick, 2011, Nature Cell Biology.