Tao Liu

发表

Identification of SVM-based classification model, synthesis and evaluation of prenylated flavonoids as vasorelaxant agents.

J. Chen, Yongzhou Hu, Xiaowu Dong, 2008, Bioorganic & medicinal chemistry.

Pharmacophore identification, docking and "in silico" screening for novel CDK1 inhibitors.

Yongzhou Hu, Xiaowu Dong, Peng Wu, 2012, Journal of molecular graphics & modelling.

Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate.

V. Palombella, Johan A. Pradeilles, Ann M. Rowley, 2016, ACS medicinal chemistry letters.

Design and synthesis of a potent histone deacetylase inhibitor.

Tao Liu, Galina V Kapustin, F. Etzkorn, 2007, Journal of medicinal chemistry.

Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression.

Shaomeng Wang, S. Gross, J. Stuckey, 2021, Journal of medicinal chemistry.

Pharmacophore identification, virtual screening and biological evaluation of prenylated flavonoids derivatives as PKB/Akt1 inhibitors.

Qiaojun He, Bo Yang, Yongzhou Hu, 2011, European journal of medicinal chemistry.

Discovery and optimization of phthalazinone derivatives as a new class of potent dengue virus inhibitors.

Wei Tang, Huazhou Ying, Youhong Hu, 2018, European journal of medicinal chemistry.

Alkenyl/thiol-derived metal-organic frameworks (MOFs) by means of postsynthetic modification for effective mercury adsorption.

Yongzhou Hu, C. Che, Xiaowu Dong, 2014, Chemistry.

Straightforward installation of carbon-halogen, carbon-oxygen and carbon-carbon bonds within metal-organic frameworks (MOF) via palladium-catalysed direct C-H functionalization.

Yongzhou Hu, C. Che, Xiaowu Dong, 2014, Chemical communications.

Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.

L. Chow, Tao Liu, Zhen Liu, 2015, Journal of medicinal chemistry.

4,5‐Diaryl‐3‐aminopyrazole Derivatives as Analogs of Combretastatin A‐4: Synthesis and Biological Evaluation

Qiaojun He, Bo Yang, J. Chen, 2011, Archiv der Pharmazie.

Design, synthesis, and biological evaluation of novel γ-carboline ketones as anticancer agents.

J. Chen, Qiaojun He, Bo Yang, 2011, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of novel N-γ-carboline arylsulfonamides as anticancer agents.

J. Chen, Qiaojun He, Bo Yang, 2010, Bioorganic & medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Prenylated Chalcones as Vasorelaxant Agents

J. Chen, Yongzhou Hu, Xiaowu Dong, 2009, Archiv der Pharmazie.

Design, Synthesis, Biological Evaluation, and Docking Studies of (S)‐Phenylalanine Derivatives with a 2‐Cyanopyrrolidine Moiety as Potent Dipeptidyl Peptidase 4 Inhibitors

Li Tang, Yongzhou Hu, Yizhe Wu, 2013, Chemical biology & drug design.

Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors.

Jia Li, Li Tang, Yongzhou Hu, 2013, Bioorganic & medicinal chemistry.

An ICT-based fluorescent switch-on probe for hydrogen sulfide in living cells.

Qiaojun He, Bo Yang, Ji Cao, 2013, Chemical communications.

Recent advances in FLT3 inhibitors for acute myeloid leukemia.

Tao Liu, Yong-cun Hu, Lexian Tong, 2020, Future medicinal chemistry.

Urea postmodified in a metal-organic framework as a catalytically active hydrogen-bond-donating heterogeneous catalyst.

Yongzhou Hu, C. Che, Xiaowu Dong, 2013, Chemical communications.

Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors.

J. Yu, Xiaodong Ma, Xiaowu Dong, 2018, Journal of medicinal chemistry.

Applying an Interspersed Online and Offline Teaching Strategy in Medicinal Chemistry to Cultivate Research Interest and Innovation Skills in Undergraduate Pharmacy Students

Huazhou Ying, Xiaowu Dong, R. Sheng, 2020 .

Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies

Yongzhou Hu, Tao Wang, Jianwei Yang, 2021, Acta pharmacologica Sinica.

Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies.

Yongzhou Hu, Yu-bo Zhou, Jia Li, 2019, European journal of medicinal chemistry.

Discovery of novel morpholino-quinoxalines as PI3Kα inhibitors by pharmacophore-based screening

Qiaojun He, Bo Yang, Yongzhou Hu, 2012 .

Synthesis and biological evaluation of new 4β-anilino-4'-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents.

Qiaojun He, Bo Yang, Yongzhou Hu, 2011, European journal of medicinal chemistry.

Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells.

L. Chow, Si Wang, Tao Liu, 2012, European journal of medicinal chemistry.

Microwave-Assisted Mannich Reaction of 2-Hydroxy-chalcones

Yongzhou Hu, Huazhou Ying, Xiaowu Dong, 2009 .

Amide-based derivatives of β-alanine hydroxamic acid as histone deacetylase inhibitors: attenuation of potency through resonance effects.

R. Codd, Tao Liu, V. Liao, 2012, Bioorganic & medicinal chemistry letters.

Design, synthesis and biological evaluation of 3-benzylideneflavanone derivatives as cytotoxic agents

Bo Yang, Yongzhou Hu, Xiaowu Dong, 2011, Medicinal Chemistry Research.

Microwave‐Assisted Mannich Reaction of 2‐Hydroxy‐chalcones.

Yongzhou Hu, Huazhou Ying, Xiaowu Dong, 2009 .

Nitrogen-containing flavonoids as CDK1/Cyclin B inhibitors: design, synthesis, and biological evaluation.

Qiaojun He, Bo Yang, Yongzhou Hu, 2007, Bioorganic & medicinal chemistry letters.

Design, synthesis, and quantitative structure-activity relationship of cytotoxic gamma-carboline derivatives.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of novel tripeptidyl epoxyketone derivatives constructed from β-amino acid as proteasome inhibitors.

Jia Li, Tao Liu, Lei Xu, 2014, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of novel podophyllotoxin derivatives bearing 4β-disulfide/trisulfide bond as cytotoxic agents

Bo Yang, Yongzhou Hu, Huazhou Ying, 2015 .

Design, synthesis, and molecular docking study of 3H‐imidazole[4,5‐c]pyridine derivatives as CDK2 inhibitors

J. Chen, Yongzhou Hu, Huazhou Ying, 2018, Archiv der Pharmazie.

Recent development and SAR analysis of colchicine binding site inhibitors.

Jing Chen, Xiaowu Dong, Yongzhou Hu, 2009, Mini reviews in medicinal chemistry.

Structure-based design, synthesis and biological evaluation of diphenylmethylamine derivatives as novel Akt1 inhibitors.

Bo Yang, Xiaowu Dong, L. Zhang, 2014, European journal of medicinal chemistry.

One-Pot Synthesis of 3-Benzylflavones

Yongzhou Hu, Xiaowu Dong, Tao Liu, 2009 .

Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors.

S. Peluso, K. West, V. Palombella, 2012, Journal of medicinal chemistry.

Synthesis and In‐Vitro Antitumor Activities of Some Mannich Bases of 9‐Alkyl‐1,2,3,4‐tetrahydrocarbazole‐1‐ones

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Archiv der Pharmazie.

XN05, a novel synthesized microtubule inhibitor, exhibits potent activity against human carcinoma cells in vitro.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Cancer letters.

Synthesis and biological evaluation of 3,4-diaryl-5-aminoisoxazole derivatives.

Qiaojun He, Bo Yang, Yongzhou Hu, 2009, Bioorganic & medicinal chemistry.

Structure-based drug design using GPCR homology modeling: toward the discovery of novel selective CysLT2 antagonists.

Xiaowu Dong, Yongzhou Hu, Tao Liu, 2013, European journal of medicinal chemistry.

Synthesis, biological evaluation and quantitative structure-activities relationship of flavonoids as vasorelaxant agents.

Yongzhou Hu, Xiaowu Dong, Peng Wu, 2009, Bioorganic & medicinal chemistry.

Curcumin: a promising agent targeting cancer stem cells.

Tao Liu, L. Qiao, S. Zang, 2014, Anti-cancer agents in medicinal chemistry.

Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT.

Xiaowu Dong, Jia Li, Tao Liu, 2022, Journal of medicinal chemistry.

Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies

Yongzhou Hu, Tao Liu, Lei Xu, 2021, Acta Pharmacologica Sinica.

Integrating docking scores, interaction profiles and molecular descriptors to improve the accuracy of molecular docking: toward the discovery of novel Akt1 inhibitors.

Bo Yang, Xiaowu Dong, Yongzhou Hu, 2014, European journal of medicinal chemistry.

The evolution paths of some reprehensive scaffolds of RORγt modulators, a perspective from medicinal chemistry.

Xixin He, Tao Liu, C. Bai, 2021, European journal of medicinal chemistry.

Part 1 Synthesis of a potent histone deacetylase inhibitor; Part 2 Studies towards a stabilized helix-turn-helix peptide

Tao Liu, 2007 .

Synthesis and biological evaluation of novel piperidin-4-ol derivatives

Yongzhou Hu, Xiaowu Dong, Wei Wei, 2012, Monatshefte für Chemie - Chemical Monthly.

Screening of new non-nucleoside reverse transcriptase inhibitors of HIV-1 based on traditional Chinese medicines database

Tao Liu, Yi Ma, Ke-zhu Wu, 2009 .

Synthesis and biological evaluation of novel 2-arylamino-3-(arylsulfonyl)quinoxalines as PI3Kα inhibitors.

Qiaojun He, Bo Yang, Yongzhou Hu, 2011, European journal of medicinal chemistry.

Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors.

Jia Li, Tao Liu, Lei Xu, 2019, European journal of medicinal chemistry.

Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles.

Yongzhou Hu, Xiaowu Dong, J. Che, 2019, European journal of medicinal chemistry.

Design, Synthesis and Biological Evaluation of Peptidyl Epoxyketone Proteasome Inhibitors Composed of β‐amino Acids

Jia Li, Yongzhou Hu, Xiaodong Ma, 2014, Chemical biology & drug design.

Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy

Yubo Zhou, Xiaowu Dong, Sheng-quan Hu, 2021 .

Design, synthesis, and biological evaluation of novel piperidine-4-carboxamide derivatives as potent CCR5 inhibitors.

Yongzhou Hu, Xiaowu Dong, Tao Liu, 2014, European journal of medicinal chemistry.

2′‐Hydroxy‐3′‐(morpholin‐4‐yl‐methyl)‐4′,6′‐dimethoxy‐2‐chloro‐chalcone

Yongzhou Hu, Tao Liu, Zhongmiao Xu, 2005 .

Design, synthesis and biological evaluation of thienopyridinones as Chk1 inhibitors.

Xiaodong Ma, Peng Peng, Tao Liu, 2014, Bioorganic & medicinal chemistry.

Pharmacophore identification, synthesis, and biological evaluation of carboxylated chalcone derivatives as CysLT1 antagonists.

Bo Yang, Yongzhou Hu, Xiaowu Dong, 2010, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of novel phenol ether derivatives as non-covalent proteasome inhibitors.

Jia Li, Tao Liu, Lei Xu, 2019, European journal of medicinal chemistry.

4,5-Diaryl-3-aminopyrazole Derivatives as Analogues of Combretastatin A-4: Synthesis and Biological Evaluation.

J. Chen, Qiaojun He, Bo Yang, 2011 .

Efficient One‐Pot Synthesis of Hydroxyflavanones by Cyclization and O‐Demethylation of Methoxychalcones

Yongzhou Hu, Huazhou Ying, Tao Liu, 2008 .

Straightforward installation of carbon-halogen, carbon-oxygen and carbon-carbon bonds within metal-organic frameworks (MOF) via palladium-catalysed direct C-H functionalization.

Yongzhou Hu, C. Che, Xiaowu Dong, 2014, Chemical communications.

Urea postmodified in a metal-organic framework as a catalytically active hydrogen-bond-donating heterogeneous catalyst.

Yongzhou Hu, C. Che, Xiaowu Dong, 2013, Chemical communications.

Design, synthesis, and biological evaluation of novel 2-methylpiperazine derivatives as potent CCR5 antagonists.

Xiaodong Ma, Tingjun Hou, Tao Liu, 2015, Bioorganic & medicinal chemistry.

Structure-based drug design using GPCR homology modeling: toward the discovery of novel selective CysLT2 antagonists.

Yongzhou Hu, Ka-na Lin, Xiaowu Dong, 2013, European journal of medicinal chemistry.

Identification of novel inhibitors of Aurora A with a 3-(pyrrolopyridin-2-yl)indazole scaffold.

Xiaodong Ma, Tao Liu, Lei Xu, 2015, Bioorganic & medicinal chemistry.

Discover Novel Covalent Inhibitors Targeting FLT3 through Hybrid Virtual Screening Strategy.

Yubo Zhou, Xiaowu Dong, Sheng-quan Hu, 2021, Biological & pharmaceutical bulletin.

Cleavage of Methyl Ethers of Flavones by Chloroaluminate Ionic Liquid

Yongzhou Hu, Tao Liu, 2004 .