Paul A. Smith

发表

Rapid prediction of chemical metabolism by human UDP-glucuronosyltransferase isoforms using quantum chemical descriptors derived with the electronegativity equalization method.

D. Winkler, J. Miners, R. Mckinnon, 2004, Journal of medicinal chemistry.

Membrane Permeability in Cyclic Peptides is Modulated by Core Conformations

Anders Hogner, Leonardo De Maria, Ekaterina Ratkova, 2020, J. Chem. Inf. Model..

Pharmacophore and quantitative structure-activity relationship modeling: complementary approaches for the rationalization and prediction of UDP-glucuronosyltransferase 1A4 substrate selectivity.

J. Miners, R. Mckinnon, M. Sorich, 2003, Journal of medicinal chemistry.

Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches.

J. Miners, P. Mackenzie, R. Mckinnon, 2004, Annual review of pharmacology and toxicology.

Recent advances in the in silico modelling of UDP glucuronosyltransferase substrates.

J. Miners, P. Mackenzie, R. Mckinnon, 2008, Current drug metabolism.

Tribology and QCM-D approaches provide mechanistic insights into red wine mouthfeel, astringency sub-qualities and the role of saliva

H. Smyth, J. Stokes, Paul A. Smith, 2021 .

The Importance of Local Chemical Structure for Chemical Metabolism by Human Uridine 5'-Diphosphate-Glucuronosyltransferase

Michael J. Sorich, John O. Miners, Ross A. McKinnon, 2007, J. Chem. Inf. Model..

Pharmacophore and quantitative structure activity relationship modelling of UDP-glucuronosyltransferase 1A1 (UGT1A1) substrates.

J. Miners, R. Mckinnon, M. Sorich, 2002, Pharmacogenetics.

Comparison of Linear and Nonlinear Classification Algorithms for the Prediction of Drug and Chemical Metabolism by Human UDP-Glucuronosyltransferase Isoforms

Paul A. Smith, Frank R. Burden, David A. Winkler, 2003, J. Chem. Inf. Comput. Sci..

Multiple pharmacophores for the investigation of human UDP-glucuronosyltransferase isoform substrate selectivity.

J. Miners, R. Mckinnon, M. Sorich, 2004, Molecular pharmacology.

Preclinical immunological characterization of rademikibart (CBP-201), a next-generation human monoclonal antibody targeting IL-4Rα, for the treatment of Th2 inflammatory diseases

Qingjian Wang, Paul A. Smith, Ying Ding, 2023, Scientific reports.

The importance of local chemical structure for chemical metabolism by human uridine 5'-diphosphate-glucuronosyltransferase.

Michael J. Sorich, John O. Miners, Ross A. McKinnon, 2006, Journal of chemical information and modeling.

Towards integrated ADME prediction: past, present and future directions for modelling metabolism by UDP-glucuronosyltransferases.

J. Miners, R. Mckinnon, M. Sorich, 2004, Journal of molecular graphics & modelling.