B. Asquith

发表

Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach

D. Laydon, C. Bangham, B. Asquith, 2015, Philosophical Transactions of the Royal Society B: Biological Sciences.

Inefficient Cytotoxic T Lymphocyte–Mediated Killing of HIV-1–Infected Cells In Vivo

Becca Asquith, Marc Lipsitch, M. Lipsitch, 2006, PLoS biology.

In vivo CD8+ T cell control of immunodeficiency virus infection in humans and macaques

Becca Asquith, A. McLean, B. Asquith, 2007, Proceedings of the National Academy of Sciences.

The relative contributions of infectious and mitotic spread to HTLV-1 persistence

D. Laydon, C. Bangham, V. Sunkara, 2019, bioRxiv.

Earlier Onset of δ-Retrovirus-Induced Leukemia after Splenectomy

A. Burny, R. Kettmann, L. Willems, 2009, PloS one.

The dynamics of T-cell fratricide: application of a robust approach to mathematical modelling in immunology.

Becca Asquith, C. Bangham, B. Asquith, 2003, Journal of theoretical biology.

Reconciling Estimates of Cell Proliferation from Stable Isotope Labeling Experiments

Yan Zhang, Elizabeth Kelly, Becca Asquith, 2015, PLoS Comput. Biol..

CD57+ Memory T Cells Proliferate In Vivo

E. Wang, J. McCune, K. Ladell, 2020, Cell reports.

Current estimates of T cell kinetics in humans

B. Asquith, R. Busch, D. Macallan, 2019, Current opinion in systems biology.

Physiologically Based Simulations of Deuterated Glucose for Quantifying Cell Turnover in Humans

T. Eissing, B. Asquith, C. Niederalt, 2017, Front. Immunol..

B-cell kinetics in humans: rapid turnover of peripheral blood memory cells.

D. Tough, C. D. de Lara, G. Griffin, 2005, Blood.

Lymphocyte kinetics in health and disease.

J. Borghans, V. V. Ganusov, B. Asquith, 2009, Trends in immunology.

Modelling Lymphocyte Dynamics In Vivo

J. Borghans, B. Asquith, 2011 .

The fate and lifespan of human monocyte subsets in steady state and systemic inflammation

Amit A. Patel, R. Flavell, D. Gilroy, 2017, The Journal of experimental medicine.

Strongyloidiasis and Infective Dermatitis Alter Human T Lymphotropic Virus-1 Clonality in vivo

D. Laydon, E. Gotuzzo, K. Verdonck, 2013, PLoS pathogens.

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

M. Block, B. Asquith, C. Niederalt, 2016 .

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux

V. Appay, K. Ladell, B. Asquith, 2016, Cell reports.

Peripheral T cell lymphopenia in COVID-19: potential mechanisms and impact

Sifan Zhang, J. Tregoning, B. Asquith, 2021, Immunotherapy advances.

Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell–mediated control of HIV-1, HCV, and HTLV-1

J. Goedert, M. Carrington, Y. Qi, 2018, Science Immunology.

KIR2DL2 Enhances Protective and Detrimental HLA Class I-Mediated Immunity in Chronic Viral Infection

J. Goedert, M. Carrington, Aidan MacNamara, 2011, PLoS pathogens.

In vivo expression of human T-lymphotropic virus type 1 basic leucine-zipper protein generates specific CD8+ and CD4+ T-lymphocyte responses that correlate with clinical outcome.

Aidan MacNamara, C. Bangham, B. Asquith, 2011, The Journal of infectious diseases.

Review. An introduction to lymphocyte and viral dynamics: the power and limitations of mathematical analysis

C. Bangham, B. Asquith, 2003, Proceedings of the Royal Society of London. Series B: Biological Sciences.

HTLV-1: persistence and pathogenesis.

B. Asquith, M. Elemans, L. Cook, 2013, Virology.

HIV-1 adaptation to NK cell-mediated immune pressure

S. Buus, M. Rasmussen, B. Asquith, 2017, PLoS pathogens.

How lymphocytes add up

R. D. de Boer, B. Asquith, 2016, Nature Immunology.

cells B-cell kinetics in humans: rapid turnover of peripheral blood memory

D. Tough, G. Griffin, B. Asquith, 2013 .

Running Title: B lymphocyte kinetics

D. Tough, G. Griffin, P. Beverley, 2013 .

The Avidity and Lytic Efficiency of the CTL Response to HTLV-11

Aidan MacNamara, Yuetsu Tanaka, C. Bangham, 2009, The Journal of Immunology.

Response to HTLV-1 The Avidity and Lytic Efficiency of the CTL

Aidan MacNamara, Yuetsu Tanaka, P. Taylor, 2009 .

Identification of proliferative and non-proliferative subpopulations of leukemic cells in CLL

B. Asquith, E. Coulter, S. Devereux, 2022, Leukemia.

In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection

D. Tough, C. D. de Lara, G. Griffin, 2007, Immunology.

Comparison of blood and lymph node cells after intramuscular injection with HIV envelope immunogens

R. Sanders, R. Shattock, B. Asquith, 2022, Frontiers in Immunology.

In contrast to HIV, KIR3DS1 does not influence outcome in HTLV-1 retroviral infection.

Aidan MacNamara, Nafisa-Katrin Seich al Basatena, B. Asquith, 2012, Human immunology.

Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and men

I. Bartha, J. Borghans, R. J. Boer, 2013 .

isotope-labeling studies in mice and humans Closing the gap between T-cell life span estimates from stable

I. Bartha, R. J. Boer, M. Ackermans, 2013 .

HLA Class I Binding of HBZ Determines Outcome in HTLV-1 Infection

Aidan MacNamara, H. Fujiwara, B. Asquith, 2010, PLoS pathogens.

Many facets of bortezomib resistance/susceptibility

B. Asquith, 2008 .

Human T cell lymphotropic virus (HTLV) type-1-specific CD8+ T cells: frequency and immunodominance hierarchy.

S. Marshall, E. Hanon, K. Gould, 2004, The Journal of infectious diseases.

The role of cytotoxic T lymphocytes in human T-cell lymphotropic virus type 1 infection.

C. Bangham, B. Asquith, Becca Asquith, 2000, Journal of theoretical biology.

Reduction of B cell turnover in chronic lymphocytic leukaemia

A. Burny, L. Willems, L. Lagneaux, 2008, British journal of haematology.

Gene activation therapy: from the BLV model to HAM/TSP patients.

A. Burny, A. Lézin, S. Olindo, 2009, Frontiers in bioscience.

Short communication an interferon-γ ELISPOT assay with two cytotoxic T cell epitopes derived from HTLV-1 tax region 161-233 discriminates HTLV-1-associated myelopathy/tropical spastic paraparesis patients from asymptomatic HTLV-1 carriers in a Peruvian population.

Aidan MacNamara, G. Vanham, E. Gotuzzo, 2011, AIDS research and human retroviruses.

Reduced cell turnover in lymphocytic monkeys infected by human T-lymphotropic virus type 1

A. Burny, R. Kettmann, J. Héraud, 2005, Oncogene.

Non-commutative geometry and the strong force

B. Asquith, 1995, hep-th/9509163.

Fratricide among CD8(+) T lymphocytes naturally infected with human T cell lymphotropic virus type I.

J. Weber, Yuetsu Tanaka, Y. Tanaka, 2000, Immunity.

Cell-mediated immune response to human T-lymphotropic virus type I.

C. Bangham, B. Asquith, A. Mosley, 2005, Viral immunology.

Spleen-Dependent Turnover of CD11b Peripheral Blood B Lymphocytes in Bovine Leukemia Virus-Infected Sheep

A. Burny, R. Kettmann, M. Bonneau, 2006, Journal of Virology.

Cell dynamics and immune response to BLV infection: a unifying model.

M. Boxus, A. Burny, R. Kettmann, 2007, Frontiers in bioscience : a journal and virtual library.

Human T Cell Memory: A Dynamic View

Becca Asquith, José A. M. Borghans, Derek C. Macallan, 2017, Vaccines.

Quantification of HTLV-1 Clonality and TCR Diversity

Daniel J. Laydon, Anat Melamed, Aaron Sim, 2014, PLoS Comput. Biol..

Innate receptors modulating adaptive T cell responses: KIR-HLA interactions and T cell-mediated control of chronic viral infections

B. Asquith, Laura Mora-Bitria, Becca Asquith, 2023, Immunogenetics.

Increased cell proliferation, but not reduced cell death, induces lymphocytosis in bovine leukemia virus-infected sheep

A. Burny, R. Kettmann, L. Willems, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The Efficiency of the Human CD8+ T Cell Response: How Should We Quantify It, What Determines It, and Does It Matter?

Becca Asquith, Marjet Elemans, Nafisa-Katrin Seich al Basatena, 2012, PLoS Comput. Biol..

Reduced Cell Turnover in Bovine LeukemiaVirus-Infected, Persistently LymphocytoticCattle

A. Burny, R. Kettmann, L. Willems, 2003, Journal of Virology.

Safety of long-term treatment of HAM/TSP patients with valproic acid.

Becca Asquith, M. Boxus, A. Lézin, 2011, Blood.

Quantifying the Impact of Human Immunodeficiency Virus-1 Escape From Cytotoxic T-Lymphocytes

Becca Asquith, Ulrich D. Kadolsky, B. Asquith, 2010, PLoS Comput. Biol..

How does HTLV-I persist despite a strong cell-mediated immune response?

C. Bangham, B. Asquith, Becca Asquith, 2008, Trends in immunology.

The Evolutionary Selective Advantage of HIV-1 Escape Variants and the Contribution of Escape to the HLA-Associated Risk of AIDS Progression

Becca Asquith, B. Asquith, 2008, PloS one.

Rates of CTL Killing in Persistent Viral Infection In Vivo

Becca Asquith, Marjet Elemans, Arnaud Florins, 2014, PLoS Comput. Biol..

Quantification of the Relative Importance of CTL, B Cell, NK Cell, and Target Cell Limitation in the Control of Primary SIV-Infection

Becca Asquith, Rodolphe Thiébaut, Marjet Elemans, 2011, PLoS Comput. Biol..

Can Non-lytic CD8+ T Cells Drive HIV-1 Escape?

Becca Asquith, Roland R. Regoes, Simon D. W. Frost, 2013, PLoS pathogens.

Identifying the immune interactions underlying HLA class I disease associations

J. Goedert, C. Thio, S. Khakoo, 2020, eLife.

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa

Christopher R. Gignoux, P. Parham, B. Henn, 2018, Journal of Immunology.

BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data

Becca Asquith, Lies Boelen, John H. Robinson, 2016, PLoS Comput. Biol..

The Rules of Human T Cell Fate in vivo

S. Nakaoka, P. Beverley, B. Asquith, 2020, Frontiers in Immunology.

Measurement of proliferation and disappearance of rapid turnover cell populations in human studies using deuterium-labeled glucose

P. Beverley, B. Asquith, H. Ghattas, 2009, Nature Protocols.

T-Cell Epitope Prediction: Rescaling Can Mask Biological Variation between MHC Molecules

Charles R. M. Bangham, Becca Asquith, Aidan MacNamara, 2009, PLoS Comput. Biol..

In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection

Charles R. M. Bangham, Becca Asquith, Yuetsu Tanaka, 2007, Proceedings of the National Academy of Sciences.

patients loads in HTLV-1associated myelopathy/tropical spastic paraparesis Histone deacetylasemediated transcriptional activation reduces proviral

S. Olindo, D. Smadja, R. Césaire, 2009 .

Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients.

Becca Asquith, Arsène Burny, A. Burny, 2007, Blood.

Is human T-cell lymphotropic virus type I really silent?

E. Hanon, C. Bangham, B. Asquith, 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

High Circulating Frequencies of Tumor Necrosis Factor Alpha- and Interleukin-2-Secreting Human T-Lymphotropic Virus Type 1 (HTLV-1)-Specific CD4+ T Cells in Patients with HTLV-1-Associated Neurological Disease

J. Weber, E. Hanon, K. Gould, 2003, Journal of Virology.

HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP

D. Laydon, M. Matsuoka, C. Bangham, 2014, Virology Journal.

Susceptibility of HBZ and Tax expressing primary HTLV-1+ T cell clones to CTL lysis

C. Bangham, B. Asquith, G. Taylor, 2011, Retrovirology.

Viral Expression Directs the Fate of B Cells in Bovine Leukemia Virus-Infected Sheep

Becca Asquith, Marjet Elemans, Arnaud Florins, 2011, Journal of Virology.

Lymphocyte kinetics: the interpretation of labelling data.

Becca Asquith, L. Willems, B. Asquith, 2002, Trends in immunology.

The Role of CTLs in Persistent Viral Infection: Cytolytic Gene Expression in CD8+ Lymphocytes Distinguishes between Individuals with a High or Low Proviral Load of Human T Cell Lymphotropic Virus Type 1

F. Martínez-Murillo, C. Bangham, B. Asquith, 2004, The Journal of Immunology.

Type 1 Load of Human T Cell Lymphotropic Virus Individuals with a High or Low Proviral Lymphocytes Distinguishes between + Infection : Cytolytic Gene Expression in CD 8 The Role of CTLs in Persistent Viral

Gillian, R. Bangham, F. Martínez-Murillo, 2004 .

The immune control of HTLV-1 infection: selection forces and dynamics.

E. Majorovits, C. Bangham, B. Asquith, 2009, Frontiers in bioscience.

A functional CD8+ cell assay reveals individual variation in CD8+ cell antiviral efficacy and explains differences in human T-lymphotropic virus type 1 proviral load.

Becca Asquith, Yuetsu Tanaka, S. Marshall, 2005, The Journal of general virology.

Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans.

I. Bartha, J. Borghans, R. D. de Boer, 2013, Blood.

Peripheral Blood B-Cell Death Compensates for Excessive Proliferation in Lymphoid Tissues and Maintains Homeostasis in Bovine Leukemia Virus-InfectedSheep

Michel Bonneau, Becca Asquith, Arnaud Florins, 2006, Journal of Virology.

Human T cell dynamics in vivo are compatible with long-lived immunological memory and stemness

D. Speiser, K. Ladell, B. Asquith, 2018 .

Rapid turnover of T cells in acute infectious mononucleosis

Yan Zhang, Becca Asquith, Hala Ghattas, 2003, European journal of immunology.

Quantification of the virus-host interaction in human T lymphotropic virus I infection

A. McLean, Yuetsu Tanaka, C. Bangham, 2005, Retrovirology.

Estimation of clonal diversity in HTLV-1 infection

D. Laydon, D. Douek, S. Darko, 2014, Retrovirology.

Measurement and modeling of human T cell kinetics.

Becca Asquith, Hala Ghattas, D. Tough, 2003, European journal of immunology.

Measurement and modeling of human T cell kinetics

D. Tough, G. Griffin, P. Beverley, 2003 .

Why Don't CD8+ T Cells Reduce the Lifespan of SIV-Infected Cells In Vivo?

Becca Asquith, Christos Gkekas, Marjet Elemans, 2011, PLoS Comput. Biol..

Quantifying HTLV‐I dynamics

B. Asquith, Charles R. M. Bangham, Becca Asquith, 2007, Immunology and cell biology.

Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester

Becca Asquith, Arnaud Florins, L. Willems, 2006, Proceedings of the Royal Society B: Biological Sciences.

Many facets of bortezomib resistance/susceptibility.

Shaji K. Kumar, S. Rajkumar, B. Asquith, 2008, Blood.

HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP

D. Laydon, M. Matsuoka, C. Bangham, 2014, Virology Journal.

Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness

K. Ladell, B. Asquith, L. Roger, 2018, PLoS biology.