É. Bonneil

发表

Noncoding regions are the main source of targetable tumor-specific antigens

P. Gendron, S. Lemieux, C. Perreault, 2018, Science Translational Medicine.

MHC class I-associated peptides derive from selective regions of the human genome.

S. Lemieux, C. Perreault, S. Mader, 2016, The Journal of clinical investigation.

H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation

P. Thibault, R. Festenstein, A. Imhof, 2011, PLoS genetics.

Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development

Mike Tyers, Jasmin Coulombe-Huntington, Pierre Thibault, 2020, Genetics.

Caterpillar- and salivary-specific modification of plant proteins.

P. Thibault, B. Driscoll, K. Thivierge, 2010, Journal of Proteome Research.

Synergistic action of co-expressed xylanase/laccase mixtures against milled sugar cane bagasse

P. Thibault, L. M. Arruda, D. S. Vieira, 2014 .

H3.3G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in Giant Cell Tumour of Bone.

Dylan M. Marchione, B. Garcia, B. Dickson, 2020, Cancer discovery.

aPKC‐mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

P. Thibault, F. Schweisguth, G. Brothers, 2007, The EMBO journal.

Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance

H. Rammensee, L. Zitvogel, C. Perreault, 2017, Immunological reviews.

Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1

M. Therrien, P. Thibault, F. Sicheri, 2018, Nature Communications.

Proteomic-Coupled-Network Analysis of T877A-Androgen Receptor Interactomes Can Predict Clinical Prostate Cancer Outcomes between White (Non-Hispanic) and African-American Groups

E. Wang, P. Thibault, M. Paliouras, 2014, PLoS ONE.

Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer

P. Gendron, S. Lemieux, C. Perreault, 2020, Cancer Immunology Research.

Undetectable histone O-GlcNAcylation in mammalian cells

Jessica K. Gagnon, P. Thibault, É. Bonneil, 2015, Epigenetics.

SUMOylation- and GAR1-Dependent Regulation of Dyskerin Nuclear and Subnuclear Localization

P. Thibault, J. Qin, É. Bonneil, 2020, Molecular and Cellular Biology.

Biochemical properties of glycosylation and characterization of a histidine acid phosphatase (phytase) expressed in Pichia pastoris.

P. Thibault, R. Ward, M. Polizeli, 2014, Protein expression and purification.

Mass Spectrometry-Based Proteomics Analyses of Integral Membrane Proteins

P. Thibault, M. Jaquinod, J. Hui, 2011 .

Accurate Quantitative Proteomic Analyses Using Metabolic Labeling and High Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS).

P. Thibault, É. Bonneil, F. McManus, 2019, Journal of proteome research.

Improvement of phosphoproteome analyses using FAIMS and decision tree fragmentation. application to the insulin signaling pathway in Drosophila melanogaster S2 cells.

P. Thibault, Gäelle Bridon, É. Bonneil, 2012, Journal of proteome research.

Analysis of the Biogenesis of Heparan Sulfate Acetyl-CoA:α-Glucosaminide N-Acetyltransferase Provides Insights into the Mechanism Underlying Its Complete Deficiency in Mucopolysaccharidosis IIIC*

A. Pshezhetsky, P. Thibault, É. Bonneil, 2010, The Journal of Biological Chemistry.

Most non-canonical proteins uniquely populate the proteome or immunopeptidome.

Maria Virginia Ruiz Cuevas, L. Staudt, J. Yewdell, 2020, Cell reports.

Drosophila S2 Cells Secrete Wingless on Exosome‐Like Vesicles but the Wingless Gradient Forms Independently of Exosomes

P. Thibault, G. Raposo, C. Alexandre, 2013, Traffic.

Multiplex multidimensional nanoLC‐MS system for targeted proteomic analyses

P. Thibault, É. Bonneil, S. Tessier, 2005, Electrophoresis.

Probing genetic variation and glycoform distribution in lectins of the Erythrina genus by mass spectrometry.

P. Thibault, N. Sharon, H. Lis, 2004, Archives of Biochemistry and Biophysics.

Enhanced sensitivity in proteomics experiments using FAIMS coupled with a hybrid linear ion trap/Orbitrap mass spectrometer.

K. Eng, P. Thibault, J. Saba, 2009, Journal of proteome research.

A Novel Proteomics Approach to Identify SUMOylated Proteins and Their Modification Sites in Human Cells*

Mathieu Courcelles, Sylvain Meloche, Pierre Thibault, 2010, Molecular & Cellular Proteomics.

Head‐to‐tail cyclization of side chain‐protected linear peptides to recapitulate genetically‐encoded cyclized peptides

M. Tyers, W. Earnshaw, P. Thibault, 2022, Peptide science.

Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors

E. Levy, M. Krajinovic, D. Sinnett, 2019, Scientific Reports.

Blood extracellular vesicles from healthy individuals regulate hematopoietic stem cells as humans age

P. Thibault, Cecilia Lässer, J. Rudan, 2020, Aging cell.

Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes

P. Thibault, É. Boilard, É. Bonneil, 2022, Cell Death & Disease.

Characterization of a solid-phase extraction device for discontinuous on-line preconcentration in capillary electrophoresis-based peptide mapping.

K. Waldron, É. Bonneil, 1999, Journal of chromatography. B, Biomedical sciences and applications.

Acyclic oligonucleotide analogues.

É. Bonneil, J. Sagi, Y. Merle, 1995, International journal of biological macromolecules.

WITHDRAWN: Global and site-specific changes in 5-methylcytosine and 5-hydroxymethylcytosine after extended post-mortem interval.

P. Jin, P. Thibault, Li Lin, 2016, Experimental and molecular pathology.

Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval

P. Jin, P. Thibault, Li Lin, 2016, Front. Genet..

Proteogenomics and Differential Ion Mobility Enable the Exploration of the Mutational Landscape in Colon Cancer Cells

Maria Virginia Ruiz Cuevas, S. Lemieux, P. Thibault, 2022, Analytical chemistry.

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity.

G. Sauvageau, Martin Sauvageau, P. Thibault, 2014, Blood.

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

L. Linares, J. Marine, F. Rambow, 2016, Molecular cell.

Generation of antioxidative peptides from Atlantic sea cucumber using alcalase versus trypsin: In vitro activity, de novo sequencing, and in silico docking for in vivo function prediction.

Shudong He, Yi Zhang, B. Simpson, 2020, Food chemistry.

Enhancement of mass spectrometry performance for proteomic analyses using high-field asymmetric waveform ion mobility spectrometry (FAIMS).

P. Thibault, É. Bonneil, S. Pfammatter, 2015, Journal of mass spectrometry : JMS.

A Host YB-1 Ribonucleoprotein Complex Is Hijacked by Hepatitis C Virus for the Control of NS3-Dependent Particle Production

P. Thibault, D. Lamarre, É. Bonneil, 2013, Journal of Virology.

Photolabeling of tissue transglutaminase reveals the binding mode of potent cinnamoyl inhibitors.

J. Pelletier, P. Thibault, W. Lubell, 2009, Biochemistry.

Kinetic characterization and identification of the acylation and glycosylation sites of recombinant human gamma-glutamyltranspeptidase.

P. Thibault, R. Castonguay, É. Bonneil, 2007, Biochemistry.

Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames

S. Lemieux, C. Perreault, P. Thibault, 2016, Nature Communications.

A high-sensitivity phospho-switch triggered by Cdk1 governs chromosome morphogenesis during cell division

Fang Wang, Claire M Brown, Éric Bonneil, 2015, Genes & development.

The microprotein Nrs1 rewires the G1/S transcriptional machinery during nitrogen limitation in budding yeast

M. Tyers, S. Moore, J. Coulombe-Huntington, 2022, PLoS biology.

A nitrogen source-regulated microprotein confers an alternative mechanism of G1/S transcriptional activation in budding yeast

M. Tyers, S. Moore, J. Coulombe-Huntington, 2020 .

Mechanisms to reduce the cytotoxicity of pharmacological nicotinamide concentrations in the pathogenic fungus Candida albicans

Mark S. Schmidt, C. Brenner, A. Verreault, 2020, The FEBS journal.

H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone

Dylan M. Marchione, B. Garcia, B. Dickson, 2020 .

Targeted Identification of SUMOylation Sites in Human Proteins Using Affinity Enrichment and Paralog-specific Reporter Ions*

P. Thibault, J. Zerweck, D. Wildemann, 2013, Molecular & Cellular Proteomics.

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

M. Tyers, G. Sauvageau, J. Coulombe-Huntington, 2021, Cell stem cell.

Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues

P. Gendron, S. Lemieux, C. Perreault, 2020, Genome Medicine.

A Novel Differential Ion Mobility Device Expands the Depth of Proteome Coverage and the Sensitivity of Multiplex Proteomic Measurements*

Derek J. Bailey, P. Thibault, M. Belford, 2018, Molecular & Cellular Proteomics.

ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)*

D. Fingar, Philippe P Roux, P. Thibault, 2010, The Journal of Biological Chemistry.

Oncogenic MAPK Signaling Stimulates mTORC1 Activity by Promoting RSK-Mediated Raptor Phosphorylation

Philippe P Roux, P. Thibault, Marie Cargnello, 2008, Current Biology.

Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.

G. Sauvageau, S. Lemieux, C. Perreault, 2021, Immunity.

IκB Kinase ε-Dependent Phosphorylation and Degradation of X-Linked Inhibitor of Apoptosis Sensitizes Cells to Virus-Induced Apoptosis

Qiang Sun, J. Hiscott, R. Lin, 2011, Journal of Virology.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

M. Tyers, J. Coulombe-Huntington, P. Thibault, 2021, Aging cell.

MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- to Large-Scale Immunopeptidome Datasets

Kevin A. Kovalchik, David J. Hamelin, L. Reiter, 2021, Molecular & cellular proteomics : MCP.

Extending the Comprehensiveness of Immunopeptidome Analyses Using Isobaric Peptide Labeling.

C. Perreault, P. Thibault, Marie-Pierre Hardy, 2020, Analytical chemistry.

Structural Maintenance of Chromosome (SMC) Proteins Link Microtubule Stability to Genome Integrity*

P. Thibault, D. D'Amours, É. Bonneil, 2014, The Journal of Biological Chemistry.

Positive Regulation of Insulin Signaling by Neuraminidase 1

A. Pshezhetsky, P. Thibault, N. Heveker, 2013, Diabetes.

Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis

P. Thibault, V. Archambault, É. Bonneil, 2020, bioRxiv.

RNA helicase DDX3X modulates herpes simplex virus 1 nuclear egress

P. Thibault, R. Lippé, É. Bonneil, 2023, Communications Biology.

Proteomics of Herpes Simplex Virus 1 Nuclear Capsids

P. Thibault, R. Lippé, É. Bonneil, 2020, Journal of Virology.

The Exon Junction Complex Controls the Splicing of mapk and Other Long Intron-Containing Transcripts in Drosophila

P. Gendron, M. Therrien, P. Thibault, 2010, Cell.

Modulation of the Phagosome Proteome by Interferon-γ*S

P. Kearney, P. Thibault, I. Jutras, 2008, Molecular & Cellular Proteomics.

Immunopeptidomics for Dummies: Detailed Experimental Protocols and Rapid, User-Friendly Visualization of MHC I and II Ligand Datasets with MhcVizPipe

Qing Ma, Chen Li, Mathieu Courcelles, 2020 .

Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro.

P. Thibault, M. Vedadi, A. Verreault, 2023, Biochimica et biophysica acta. Gene regulatory mechanisms.

Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling

Pierre Thibault, Chantal Durette, P. Thibault, 2014, Nature Communications.

Proteomic Profiling of a Mouse Model for Ovarian Granulosa Cell Tumor Identifies VCP as a Highly Sensitive Serum Tumor Marker in Several Human Cancers

A. Mes-Masson, P. Thibault, R. Romieu-Mourez, 2012, PloS one.

Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progression

Philippe P Roux, P. Thibault, Peng Wang, 2013, The Journal of cell biology.

Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers

S. Lemieux, C. Perreault, P. Thibault, 2016, Leukemia.

Integrated microfluidic devices with enhanced separation performance: application to phosphoproteome analyses of differentiated cell model systems.

Pierre Thibault, Kevin Killeen, K. Killeen, 2006, Journal of separation science.

Histone Deacetylase Inhibitors Globally Enhance H3/H4 Tail Acetylation Without Affecting H3 Lysine 56 Acetylation

P. Thibault, G. Ferbeyre, V. Bourdeau, 2012, Scientific Reports.

On-line system for peptide mapping by capillary electrophoresis at sub-micromolar concentrations.

K. Waldron, É. Bonneil, 2000, Talanta.

Presence of diabetes autoantigens in extracellular vesicles derived from human islets

P. Thibault, S. Paraskevas, É. Boilard, 2017, Scientific Reports.

Early defects in mucopolysaccharidosis type IIIC disrupt excitatory synaptic transmission

J. Lacaille, A. Pshezhetsky, P. Thibault, 2021, JCI insight.

Early defects in lysosomal storage diseases disrupt excitatory synaptic transmission

J. Lacaille, A. Pshezhetsky, P. Thibault, 2020, bioRxiv.

An Enhanced Mass Spectrometry Approach Reveals Human Embryonic Stem Cell Growth Factors in Culture*S

G. Lajoie, P. Thibault, Morag H. Stewart, 2009, Molecular & Cellular Proteomics.

An Enhanced Mass Spectrometry Approach Reveals Human Embryonic Stem Cell Growth Factors in Culture Running title: Enhanced Protein Profiling and hESC Growth Factors

G. Lajoie, P. Thibault, Morag H. Stewart, 2008 .

Polo kinase regulates mitotic chromosome condensation by hyperactivation of condensin DNA supercoiling activity.

D. D'Amours, M. Douziech, Hery Ratsima, 2009, Molecular cell.

Gas-Phase Enrichment of Multiply Charged Peptide Ions by Differential Ion Mobility Extend the Comprehensiveness of SUMO Proteome Analyses

P. Thibault, É. Bonneil, F. McManus, 2018, Journal of The American Society for Mass Spectrometry.

Reproducibility of a solid-phase trypsin microreactor for peptide mapping by capillary electrophoresis

K. Waldron, É. Bonneil, M. Mercier, 2000 .

Application of Microfluidic Devices to Proteomics Research

D. Jed Harrison, Pierre Thibault, D. J. Harrison, 2002, Molecular & Cellular Proteomics.

Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors

E. Levy, M. Krajinovic, D. Sinnett, 2019, Scientific Reports.

Integrated microfluidic device for mass spectrometry-based proteomics and its application to biomarker discovery programs.

Pierre Thibault, P. Thibault, Marie-Hélène Fortier, 2005, Analytical chemistry.

Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q-Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer.

Derek J. Bailey, John P. Rochon, P. Thibault, 2021, Analytical chemistry.

Improvement of Quantitative Measurements in Multiplex Proteomics Using High-Field Asymmetric Waveform Spectrometry.

P. Thibault, É. Bonneil, S. Pfammatter, 2016, Journal of proteome research.

Improvement in peptide detection for proteomics analyses using NanoLC-MS and high-field asymmetry waveform ion mobility mass spectrometry.

Pierre Thibault, K. Eng, P. Thibault, 2005, Analytical chemistry.

Engineering the Pattern of Protein Glycosylation Modulates the Thermostability of a GH11 Xylanase*

P. Thibault, D. S. Vieira, R. Ward, 2013, The Journal of Biological Chemistry.

Insights into the insect salivary gland proteome: diet-associated changes in caterpillar labial salivary proteins.

H. Najafabadi, P. Thibault, J. Bede, 2013, Journal of insect physiology.

N-Terminal Ubiquitination of Extracellular Signal-Regulated Kinase 3 and p21 Directs Their Degradation by the Proteasome

P. Thibault, S. Meloche, G. Rodier, 2004, Molecular and Cellular Biology.

Elucidating Novel Hepatitis C Virus–Host Interactions Using Combined Mass Spectrometry and Functional Genomics Approaches*

Vincent Lotteau, Pierre Thibault, Éric Bonneil, 2013, Molecular & Cellular Proteomics.

Extended Synaptotagmin 1 Interacts with Herpes Simplex Virus 1 Glycoprotein M and Negatively Modulates Virus-Induced Membrane Fusion

P. Thibault, R. Lippé, É. Bonneil, 2017, Journal of Virology.

K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ)

B. Andrews, D. Shore, Charles Boone, 2023, bioRxiv.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress responses

Amber L. Couzens, M. Tyers, A. Gingras, 2018, bioRxiv.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Amber L. Couzens, M. Tyers, A. Gingras, 2020, Nature Communications.

Transposable elements regulate thymus development and function

P. Gendron, S. Lemieux, C. Perreault, 2023, bioRxiv.

Phosphorylation of IRF-3 on Ser 339 Generates a Hyperactive Form of IRF-3 through Regulation of Dimerization and CBP Association

P. Thibault, S. Meloche, N. Grandvaux, 2008, Journal of Virology.

[Identification of proteins associated with transcription factors HOXA9 and E2A-PBX1 by tandem affinity purification].

É. Bonneil, J. Bijl, S. Bourassa, 2017 .

Identification of proteins associated with transcription factors HOXA9 and E2A-PBX1 by tandem affinity purification

É. Bonneil, J. Bijl, S. Bourassa, 2017, Molecular Biology.

Identification of PP2A-B55 targets uncovers regulation of emerin during nuclear envelope reassembly in Drosophila

P. Thibault, Myreille Larouche, V. Archambault, 2023, Open Biology.

Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1.

Christos G. Gkogkas, Inês S. Amorim, Y. Atlasi, 2022, Brain : a journal of neurology.

A Rapid and Efficient Method for the Extraction of Histone Proteins.

P. Thibault, R. Rajan, A. Verreault, 2023, Journal of proteome research.

p38γ and p38δ modulate innate immune response by regulating MEF2D activation

N. Sonenberg, S. Ley, A. Risco, 2022, bioRxiv.

SPAT: Surface Protein Annotation Tool

G. Boucher, G. Sauvageau, P. Thibault, 2023, bioRxiv.

Identification of proteins associated with transcription factors HOXA9 and E2A-PBX1 by tandem affinity purification

É. Bonneil, J. Bijl, S. Bourassa, 2017, Molecular Biology.

Thermostability of a GH 11 Xylanase Glycosylation Modulates the Engineering the Pattern of Protein Glycobiology and Extracellular

P. Thibault, D. S. Vieira, R. Ward, 2013 .

Elucidating Novel Hepatitis C Virus–Host Interactions Using Combined Mass Spectrometry and Functional Genomics Approaches*

B. de Chassey, F. Pradezynski, V. Lotteau, 2013, Molecular & Cellular Proteomics.

Polo kinase regulates mitotic chromosome condensation by hyperactivation of condensin DNA supercoiling activity.

D. D'Amours, M. Douziech, Hery Ratsima, 2009, Molecular cell.

ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)*

D. Fingar, Philippe P Roux, P. Thibault, 2010, The Journal of Biological Chemistry.

MHC class I-associated peptides derive from selective regions of the human genome.

S. Lemieux, C. Perreault, S. Mader, 2016, The Journal of clinical investigation.

Live Cell Painting: New nontoxic dye to probe cell physiology in high content screening

É. Bonneil, D. Andrews, Martin Cottet, 2023, SLAS Discovery.

Caterpillar- and salivary-specific modification of plant proteins.

P. Thibault, B. Driscoll, J. Bede, 2010, Journal of proteome research.

Involvement of Extracellular Vesicles in the Proinflammatory Response to Clozapine: Implications for Clozapine-Induced Agranulocytosis

J. Uetrecht, É. Bonneil, A. Jee, 2024, The Journal of Pharmacology and Experimental Therapeutics.

Application of Microfluidic Devices to Proteomics

D. J. Harrison, Can Wang, P. Thibault, 2002 .

Application of Microfluidic Devices to Proteomics Research IDENTIFICATION OF TRACELEVEL TRACELEVEL TRACELEVEL PROTEIN DIGESTS AND AFFINITY CAPTURE OF TARGET PEPTIDES *

D. J. Harrison, Can Wang, P. Thibault, 2002 .

Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption

A. Pshezhetsky, L. Sturiale, A. Palmigiano, 2023, JCI insight.

Immunotherapeutic targeting of surfaceome heterogeneity in AML.

G. Boucher, Vincent-Philippe Lavallée, J. Hébert, 2024, Cell reports.

CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216

G. Sauvageau, B. Wilhelm, Philippe P Roux, 2023, Blood advances.

Comprehensive proteomic analysis of HCoV-OC43 virions and virus-modulated extracellular vesicles

R. Lippé, É. Bonneil, Pierre Thibault, 2024, bioRxiv.

Transposable elements regulate thymus development and function

Céline M. Laumont, É. Bonneil, J. Laverdure, 2024, bioRxiv.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Amber L. Couzens, M. Tyers, A. Gingras, 2020, Nature Communications.

Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression

N. Shahani, É. Bonneil, Gogce Crynen, 2024, Cellular and molecular life sciences : CMLS.

Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines.

J. Hébert, A. Marinier, É. Bonneil, 2024, Leukemia.