T. Negishi

发表

Influence of neighbouring base sequences on the mutagenesis induced by 7,8-dihydro-8-oxoguanine in yeast.

K. Okamoto, Chinwei Yung, Yoji Okugawa, 2008, Mutagenesis.

Spermidine-analogous triamines suppressed the growth of Candida albicans.

E. Takahashi, K. Okamoto, S. Arimoto, 2013, Biological & pharmaceutical bulletin.

Dietary inhibitors of mutagenesis and carcinogenesis.

H. Hayatsu, S. Arimoto, T. Negishi, 1988, Mutation research.

Porphyrins as possible preventers of heterocyclic amine carcinogenesis.

H. Hayatsu, T. Negishi, S. Arimoto-Kobayashi, 1999, Cancer letters.

Mutagenicities of N-nitrosodimethylamine and N-nitrosodiethylamine in Drosophila and their relationship to the levels of O-alkyl adducts in DNA.

J. Thomale, H. Hayatsu, M. Rajewsky, 1999, Mutation research.

Porphyrins as potential inhibitors against exposure to carcinogens and mutagens.

H. Hayatsu, S. Arimoto, T. Negishi, 1993, Mutation research.

Somatic cell mutations caused by 365 nm LED-UVA due to DNA double-strand breaks through oxidative damage.

Y. Kamei, K. Okamoto, Y. Ibuki, 2014, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

The involvement of cell cycle checkpoint-mutations in the mutagenesis induced in Drosophila by a longer wavelength light band of solar UV

K. Hieda, T. Negishi, Y. Furusawa, 2002, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae.

Toshinori Suzuki, T. Hatano, T. Negishi, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Inhibitory effect of Actinidia arguta on mutagenesis, inflammation and two-stage mouse skin tumorigenesis

T. Negishi, S. Arimoto-Kobayashi, Ryoko Hida, 2016, Genes and Environment.

Isolation and characterization of the human chromosomal gene for prostacyclin-stimulating factor.

H. Nawata, T. Negishi, F. Umeda, 1996, Journal of biochemistry.

Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin.

T. Kamataki, E. Takahashi, K. Okamoto, 2002, Mutation research.

Suppression of genotoxicity of carcinogens by (-)-epigallocatechin gallate.

T. Okuda, H. Hayatsu, S. Arimoto, 1992, Preventive medicine.

Inhibitory effects of beer on mutation in the Ames test and DNA adduct formation in mouse organs induced by 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

Toshimitsu Konuma, E. Takahashi, K. Okamoto, 2006, Biological & pharmaceutical bulletin.

Production and properties of lipase of Aeromonas sobria

Y. Takeda, E. Takahashi, K. Okamoto, 2012, Microbiology and immunology.

Chloroethylating anticancer drug-induced mutagenesis and its repair in Escherichia coli

E. Takahashi, K. Okamoto, S. Arimoto, 2019, Genes and Environment.

Increased Levels of 8‐Hydroxy‐2′‐Deoxyguanosine in Drosophila Larval DNA after Irradiation with 364‐nm Laser Light but not with X‐rays

Masakatsu Watanabe, Takanori Nakamura, T. Negishi, 2007, Photochemistry and photobiology.

Inhibitory effect of chlorophyll on the genotoxicity of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2).

H. Hayatsu, S. Arimoto, T. Negishi, 1989, Carcinogenesis.

Dietary inhibitors against mutagenesis and carcinogenesis.

H. Hayatsu, S. Arimoto, T. Negishi, 1993, Basic life sciences.

Alternative methods to evaluate the protective ability of sunscreen against photo-genotoxicity.

K. Okamoto, T. Negishi, M. Toyoshima, 2004, Journal of photochemistry and photobiology. B, Biology.

Exposure to Cigarette Smoke Increases Urate Level and Decreases Glutathione Level in Larval Drosophila melanogaster

K. Okamoto, Toshinori Suzuki, S. Arimoto, 2011 .

Indolo[3,2-b]quinoline Derivatives Suppressed the Hemolytic Activity of Beta-Pore Forming Toxins, Aerolysin-Like Hemolysin Produced by Aeromonas sobria and Alpha-Hemolysin Produced by Staphylococcus aureus.

E. Takahashi, S. Miyoshi, K. Okamoto, 2016, Biological & pharmaceutical bulletin.

Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency

R. Schaaper, M. Sekine, K. Okamoto, 2008, Mutation research.

Genome stability in Drosophila: Mismatch repair and genome stability

T. Negishi, 2021, Genome Stability.

Cleavage specificity of the serine protease of Aeromonas sobria, a member of the kexin family of subtilases.

E. Takahashi, K. Okamoto, H. Yamanaka, 2006, FEMS microbiology letters.

Increase of somatic cell mutations in oxidative damage-sensitive drosophila

K. Okamoto, T. Negishi, S. Arimoto-Kobayashi, 2018, Genes and Environment.

Hypersensitivity of a Urate-null Strain of Drosophila melanogaster to the Toxic Effects of Environmental Cigarette Smoke

K. Okamoto, Toshinori Suzuki, S. Arimoto, 2009 .

Evaluation of Oxidative Damage Induced by Natural Sunlight in Drosophila

T. Negishi, H. Kasai, Ritsuo Arakawa, 2006 .

Novel antimutagenic factors derived from the edible mushroom Agrocybe cylindracea.

E. Takahashi, K. Okamoto, S. Arimoto, 2005, Mutation research.

Somatic‐cell mutation induced by UVA and monochromatic UV radiation in repair‐proficient and ‐deficient Drosophila melanogaster ¶

T. Hara, Masakatsu Watanabe, Keiji Suzuki, 2001 .

Research Note Somatic-cell mutation induced by UVA and monochromatic UV radiation in repair-proficient and -deficientDrosophila melanogaster ¶

T. Hara, Masakatsu Watanabe, Keiji Suzuki, 2001 .

Preventive effects of anthraquinone food pigments on the DNA damage induced by carcinogens in Drosophila.

E. Takahashi, H. Hayatsu, T. Negishi, 2001, Mutation research.

Antigenotoxic activity of natural chlorophylls.

H. Hayatsu, T. Negishi, H. Rai, 1997, Mutation research.

Inhibitory Activity of Natural Chlorophylls on the Mutagenicity of 4-Nitroquinoline 1-Oxide and 3-Amino-1-Methyl-5H-Pyrido[4,3-b]indole in Drosophila

H. Hayatsu, S. Arimoto, T. Negishi, 1997 .

Inhibitory activity of chlorophyllin on the genotoxicity of carcinogens in Drosophila.

H. Hayatsu, T. Negishi, T. Shiotani, 1994, Cancer letters.

PYRIDO(4,3-£)INDOLE (Trp-P-2) IN DROSOPHILA BY CHLOROPHYLL

H. Hayatsu, S. Arimoto, T. Negishi, 1990 .

Inhibition of the genotoxicity of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) in Drosophila by chlorophyll.

H. Hayatsu, S. Arimoto, T. Negishi, 1990, Basic life sciences.

E. coli mismatch repair enhances AT-to-GC mutagenesis caused by alkylating agents.

E. Takahashi, K. Okamoto, S. Arimoto, 2017, Mutation research.

Novel Antimutagenic Proteins in the Edible Mushroom Agrocybe cylindracea

E. Takahashi, K. Okamoto, S. Arimoto, 2012 .

Mutagenicity and NO formation from UVA irradiated N-nitrosoproline, and characterization of photoproduct formed in UVA-irradiated mixture of N-nitrosoproline with 2-′deoxyguanosine in neutral solution

K. Okamoto, Toshinori Suzuki, T. Negishi, 2014 .

Chemopreventive properties of chlorophylls towards aflatoxin B1: a review of the antimutagenicity and anticarcinogenicity data in rainbow trout.

J. Hendricks, G. Bailey, H. Hayatsu, 1998, Mutation research.

Modification of adenine and cytosine derivatives with bromoacetaldehyde.

H. Hayatsu, K. Negishi, T. Negishi, 1980 .

Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells.

K. Okamoto, Keita Saito, H. Kataoka, 2012, Chemosphere.

Inhibitory effect of Actinidia arguta on mutagenesis, inflammation and two-stage mouse skin tumorigenesis

T. Negishi, S. Arimoto-Kobayashi, Ryoko Hida, 2016, Genes and Environment.

Chemopreventive Effects of the Juice of Vitis coignetiae Pulliat on Two-Stage Mouse Skin Carcinogenesis

T. Negishi, S. Arimoto-Kobayashi, T. Kamiya, 2013, Nutrition and cancer.

Inhibitory effect of saturated fatty acids on the mutagenicity of N-nitrosodimethylamine.

H. Hayatsu, T. Negishi, 1984, Mutation research.

Near ultraviolet radiation-mediated reaction between N-nitrosoproline and DNA: Isolation and identification of two new adducts, (R)- and (S)-8-(2-pyrrolidyl)-2′-deoxyguanosine

K. Okamoto, Toshinori Suzuki, T. Hatano, 2014 .

The genotoxicities of N-nitrosamines in Drosophila melanogaster in vivo: the correlation of mutagenicity in the wing spot test with the DNA damages detected by the DNA-repair test.

H. Hayatsu, T. Negishi, T. Shiotani, 1991, Mutation research.

Distinct pathways for repairing mutagenic lesions induced by methylating and ethylating agents.

R. Schaaper, E. Takahashi, K. Okamoto, 2013, Mutagenesis.

Mismatch repair systems might facilitate the chromosomal recombination induced by N-nitrosodimethylamine, but not by N-nitrosodiethylamine, in Drosophila.

K. Okamoto, T. Negishi, K. Miyamoto, 2020, Mutagenesis.

Inhibition of the mutagenicity of amino acid pyrolysis products by hemin and other biological pyrrole pigments.

H. Hayatsu, S. Arimoto, T. Negishi, 1980, Biochemical and biophysical research communications.

UVA causes specific mutagenic DNA damage through ROS production, rather than CPD formation, in Drosophila larvae.

T. Matsunaga, M. Wakasugi, T. Negishi, 2023, Mutation research. Genetic toxicology and environmental mutagenesis.

Mutagenicity of carbadox and several quinoxaline 1,4-dioxide derivatives.

H. Hayatsu, T. Negishi, K. Tanaka, 1980, Chemical & pharmaceutical bulletin.

Mutagenicity of quinoline derivatives and analogs-quinoxaline 1,4-dioxide is a potent mutagen.

H. Hayatsu, T. Negishi, S. Hayakawa, 1979, Chemical & pharmaceutical bulletin.

Inhibitory effect of hemin on the mutagenic activities of carcinogens.

H. Hayatsu, S. Arimoto, T. Negishi, 1980, Cancer letters.

Somatic-cell mutation induced by short exposures to cigarette smoke in urate-null, oxidative stress-sensitive Drosophila.

K. Okamoto, Toshinori Suzuki, T. Negishi, 2015, Mutagenesis.

Inhibition of N-nitrosation of secondary amines in vitro by tea extracts and catechins.

H. Hayatsu, T. Negishi, K. Tanaka, 1998, Mutation research.

Somatic cell mutation and photoproduct formation in Drosophila induced by monochromatic UV light in sunlight

Masakatsu Watanabe, O. Nikaido, K. Hieda, 2000 .

Somatic cell mutation induced by sunlight in Drosophila.

O. Nikaido, T. Negishi, M. Mochizuki, 1999, Journal of epidemiology.

The genotoxicity of UVA irradiation in Drosophila melanogaster and the synergistic action of 8-methoxypsoralen and UVA.

H. Hayatsu, T. Negishi, F. Tanabe, 1992, Carcinogenesis.

Involvement of the drug efflux protein TolC in mutagenicity induced by MNNG or Trp-P-2.

E. Takahashi, K. Okamoto, H. Yamanaka, 2006, Mutation research.

Somatic-cell mutation induced by UVA and monochromatic UV radiation in repair-proficient and -deficient Drosophila melanogaster¶

T. Hara, Masakatsu Watanabe, Keiji Suzuki, 2001, Photochemistry and Photobiology.

Mutation and apoptosis are well-coordinated for protecting against DNA damage-inducing toxicity in Drosophila

T. Negishi, A. Fukunaga, Yuko Hamatake, 2023, Genes and Environment.

Maturation pathway of metalloprotease produced by Aeromonas sobria

Y. Takeda, G. Nair, E. Takahashi, 2010, Microbiology and immunology.

Properties of Hemolysin and Protease Produced by Aeromonas trota

Haruka Ozaki, E. Takahashi, K. Okamoto, 2014, PloS one.

Analysis of carboxy terminal domain of metalloprotease of elastolytic Aeromonas hydrophila.

E. Takahashi, K. Okamoto, A. Tateishi, 2013, Biological & pharmaceutical bulletin.

Enhancement of phase II enzyme activity by purpurin resulting in the suppression of MeIQx-DNA-adduct formation in mice.

E. Takahashi, K. Okamoto, S. Arimoto, 2007, Mutation research.

Effects of Oral Administration of Non-genotoxic Hepato-hypertrophic Compounds on Metabolic Potency of Rat Liver

A. Nishikawa, T. Nunoshiba, E. Takahashi, 2014 .

Inhibitory effects of (-)-epigallocatechin gallate on the mutation, DNA strand cleavage, and DNA adduct formation by heterocyclic amines.

K. Okamoto, H. Hayatsu, T. Negishi, 2003, Journal of agricultural and food chemistry.

Inhibition of DNA Adduct Formation and Mutagenic Action of 3‐Amino‐l‐methyl‐5H‐pyrido[4,3‐b]indole by Chlorophyllin‐chitosan in rpsL Transgenic Mice

H. Hayatsu, K. Negishi, T. Negishi, 2001, Japanese journal of cancer research : Gann.

Inhibition of 2‐Amino‐3, 8‐dimethylimidazo[4,5‐f]quinoxaline‐mediated DNA‐adduct Formation by Chlorophyllin in Drosophila

H. Hayatsu, T. Negishi, C. Sugiyama, 1996, Japanese journal of cancer research : Gann.

Genome Stability in Drosophila

T. Negishi, 2016 .

No effects of chlorophyllin on IQ (2-amino-3-methylimidazo[4,5-f]-quinoline)-genotoxicity and -DNA adduct formation in Drosophila.

H. Hayatsu, T. Negishi, C. Sugiyama, 2004, Biological & pharmaceutical bulletin.

The enhancing effect of cysteine and its derivatives on the mutagenic activities of the tryptophan-pyrolysis products, Trp-P-1 and Trp-P-2.

H. Hayatsu, T. Negishi, 1979, Biochemical and biophysical research communications.

Mutagenicity and clastogenicity of extracts of Helicobacter pylori detected by the Ames test and in the micronucleus test using human lymphoblastoid cells.

K. Okamoto, T. Negishi, T. Ishikawa, 2015, Mutagenesis.

DNA lesion and mutagenesis induced in phageM13mp2 by UVA, UVB and UVC irradiation.

K. Negishi, T. Negishi, Y. Izumizawa, 2000, Nucleic acids symposium series.

A sensitive assay for mutagenic activity of N-nitrosamines and its use for detection of modulators of the mutagenicity.

H. Hayatsu, T. Negishi, Y. Ohara, 1982, IARC scientific publications.

Somatic cell mutations caused by 365 nm LED-UVA due to DNA double-strand breaks through oxidative damage

Y. Kamei, K. Okamoto, Y. Ibuki, 2014, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Mutagenicity and clastogenicity of extracts of Helicobacter pylori detected by the Ames test and in the micronucleus test using human lymphoblastoid cells.

K. Okamoto, T. Negishi, T. Ishikawa, 2015, Mutagenesis.