A. Hurwitz

发表

MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer

R. Stephens, C. Croce, M. Yi, 2011, Nucleic acids research.

Dendritic Cells and Cancer: Development, Dysfunction and Therapeutic Targets

S. K. Watkins, A. Hurwitz, S. Watkins, 2013 .

FOXO3: A master switch for regulating tolerance and immunity in dendritic cells.

S. K. Watkins, A. Hurwitz, S. Watkins, 2012, Oncoimmunology.

Immune suppression in the tumor microenvironment: a role for dendritic cell-mediated tolerization of T cells

S. K. Watkins, A. Hurwitz, S. Watkins, 2012, Cancer Immunology, Immunotherapy.

Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow1

G. Trinchieri, R. Kastelein, J. Wigginton, 2009, The Journal of Immunology.

Bone Marrow Neuroblastoma Metastases in the Liver and and Complete Regression of Disseminated Sensitization , Tumor-Specific CTL Reactivity IL-27 and IL-2 : Enhancement of T Cell Immunologic and Therapeutic Synergy of and

G. Trinchieri, R. Kastelein, J. Wigginton, 2009 .

CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma.

J. Allison, D. Leach, A. Hurwitz, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.

B. Foster, J. Allison, N. Greenberg, 2000, Cancer research.

Tumor-Induced Immune Suppression

D. Gabrilovich, A. Hurwitz, 2014, Springer New York.

T Cell Avidity and Tumor Immunity: Problems and Solutions

K. Stagliano, A. Hurwitz, Ziqiang Zhu, 2014, Cancer Microenvironment.

Accentuating Tumor Immunity Through Costimulation

A. Weinberg, A. Hurwitz, Dean E. Evans, 2004 .

Autoimmune depigmentation following sensitization to melanoma antigens.

A. Hurwitz, Qingyong Ji, 2004, Methods in molecular medicine.

Expression of Costimulatory TNFR2 Induces Resistance of CD4+FoxP3− Conventional T Cells to Suppression by CD4+FoxP3+ Regulatory T Cells

A. Hurwitz, Xin Chen, J. Oppenheim, 2010, The Journal of Immunology.

Cutting Edge: Tumor-Specific CD8+ T Cells Infiltrating Prostatic Tumors Are Induced to Become Suppressor Cells1

K. Stagliano, M. Anderson, N. Greenberg, 2009, The Journal of Immunology.

Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer.

B. Foster, J. Allison, N. Greenberg, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Engagement of OX40 Enhances Antigen-Specific CD4+ T Cell Mobilization/Memory Development and Humoral Immunity: Comparison of αOX-40 with αCTLA-41

A. Weinberg, A. Hurwitz, C. Thalhofer, 2001, The Journal of Immunology.

Augmentation of T Cell Levels and Responses Induced by Androgen Deprivation1

B. Leibovich, M. T. Moser, J. Allison, 2004, The Journal of Immunology.

The role of the blood-brain barrier in HIV infection of the central nervous system.

J. Berman, A. Hurwitz, W. Lyman, 1994, Advances in neuroimmunology.

Human fetal astrocytes induce the expression of blood-brain barrier specific proteins by autologous endothelial cells

J. Berman, A. Hurwitz, W. Lyman, 1993, Brain Research.

Development of regulatory T cells requires IL-7R (cid:1) stimulation by IL-7 or TSLP

W. Leonard, W. Li, R. Mazzucchelli, 2008 .

Costimulatory wars: the tumor menace.

A. van Elsas, A. Hurwitz, E. Kwon, 2000, Current opinion in immunology.

Murine Model of Prostate Cancer Despite Efficient Initial Priming in a Primary Tolerization of Tumor-Specific T Cells

M. Anderson, N. Greenberg, A. Hurwitz, 2007 .

Tolerization of Tumor-Specific T Cells Despite Efficient Initial Priming in a Primary Murine Model of Prostate Cancer1

M. Anderson, N. Greenberg, A. Hurwitz, 2007, The Journal of Immunology.

Modulation of T Cell Tolerance in a Murine Model for Immunotherapy of Prostatic Adenocarcinoma

A. Hurwitz, 2006 .

Tumor Necrosis Factor ol Induces Adhesion Molecule Expression on H u m a n Fetal Astrocytes

J. Berman, T. Calderon, A. Hurwitz, 2003 .

Tumor necrosis factor alpha induces adhesion molecule expression on human fetal astrocytes

J. Berman, T. Calderon, A. Hurwitz, 1992, Journal of Experimental Medicine.

Tumor necrosis factor α and transforming growth factor β upregulate astrocyte expression of monocyte chemoattractant protein-1

A. Hurwitz, W. Lyman, Joan W. Herman, 1995, Journal of Neuroimmunology.

Provision of Granulocyte-Macrophage Colony-Stimulating Factor Converts an Autoimmune Response to a Self-Antigen into an Antitumor Response

David C. Gondek, A. Hurwitz, Qingyong Ji, 2005, The Journal of Immunology.

Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis

J. Allison, R. Sobel, M. Krummel, 1997, Journal of Neuroimmunology.

Immunity to murine prostatic tumors: continuous provision of T-cell help prevents CD8 T-cell tolerance and activates tumor-infiltrating dendritic cells.

W. Alvord, M. Anderson, S. K. Watkins, 2009, Cancer research.

T cell tolerance to tumors and cancer immunotherapy.

M. Anderson, A. Hurwitz, A. Malyguine, 2007, Advances in experimental medicine and biology.

Melanoma Progression Despite Infiltration by In Vivo-primed TRP-2–specific T Cells

R. Leighty, V. Singh, A. Hurwitz, 2009, Journal of immunotherapy.

Antitumor Response Autoimmune Response to a Self-Antigen into Colony-Stimulating Factor Converts an Provision of Granulocyte-Macrophage

David C. Gondek, A. Hurwitz, Qingyong Ji, 2005 .

Manipulation of costimulatory signals to enhance antitumor T-cell responses.

J. Allison, D. Leach, A. Hurwitz, 1995, Current opinion in immunology.

29th Annual meeting of the Society for Immunotherapy of Cancer (SITC)

H. Kohrt, D. Speiser, W. Urba, 2015, Journal of Immunotherapy for Cancer.

Modulation of costimulation to enhance tumor immunity

A. Hurwitz, B. Vesosky, 2003, Cancer Immunology, Immunotherapy.

The TRAMP Mouse as a Model for Prostate Cancer

B. Foster, J. Allison, N. Greenberg, 2001, Current protocols in immunology.

Clonal analysis of graft-infiltrating lymphocytes from renal and cardiac biopsies. Dominant rearrangements of TcR beta genes and persistence of dominant rearrangements in serial biopsies.

R. Colvin, J. Fallon, A. Hurwitz, 1990, Human immunology.

Prostate Cancer

J. Allison, A. Hurwitz, E. Kwon, 2003, BioDrugs.

Modulation of T-Cell Activation in an Experimental Model of Mammary Carcinoma.

A. Hurwitz, 1999 .

Engagement of OX40 enhances antigen-specific CD4(+) T cell mobilization/memory development and humoral immunity: comparison of alphaOX-40 with alphaCTLA-4.

A. Weinberg, A. Hurwitz, C. Thalhofer, 2001, Journal of immunology.

Manipulation of T Cell Activation in the Anti-Tumor Immune Response

J. Allison, D. Leach, A. Hurwitz, 1998 .

Tumor necrosis factor alpha and transforming growth factor beta upregulate astrocyte expression of monocyte chemoattractant protein-1.

J. Berman, A. Hurwitz, W. Lyman, 1995, Journal of neuroimmunology.

Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice

J. Allison, R. Sobel, A. Hurwitz, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Enhancement of the anti‐tumor immune response using a combination of interferon‐γ and B7 expression in an experimental mammary carcinoma

J. Allison, A. Hurwitz, S. E. Townsend, 1998, International journal of cancer.

Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy.

B. Foster, J. Allison, N. Greenberg, 1999, Proceedings of the National Academy of Sciences of the United States of America.

CD4+ T Cell Help Selectively Enhances High-Avidity Tumor Antigen-Specific CD8+ T Cells

R. Leighty, V. Bronte, V. Singh, 2015, The Journal of Immunology.

Cellular and molecular pathways in the tumor immunoenvironment: 3rd Cancer Immunotherapy and Immunomonitoring (CITIM) meeting, 22–25 April 2013, Krakow, Poland

W. Murphy, R. Apte, M. Shurin, 2013, Cancer Immunology, Immunotherapy.

Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.

W. Leonard, W. Li, R. Mazzucchelli, 2008, Blood.

Elucidating the Autoimmune and Antitumor Effector Mechanisms of a Treatment Based on Cytotoxic T Lymphocyte Antigen-4 Blockade in Combination with a B16 Melanoma Vaccine

R. Offringa, C. Melief, J. Allison, 2001, The Journal of experimental medicine.

Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation

J. Allison, A. van Elsas, A. Hurwitz, 1999, The Journal of experimental medicine.

Transcriptional Regulation of Dendritic Cells in the Tumor Microenvironment

K. Stagliano, Aimin Jiang, A. Hurwitz, 2014 .

CD8+ T cell self-tolerance permits responsiveness but limits tissue damage

S. Jameson, A. Hurwitz, T. Knutson, 2021, eLife.

MicroRNA-106b-25 cluster expression is associated with early disease recurrence and targets caspase-7 and focal adhesion in human prostate cancer

Y Yang, A. Schetter, R. Stephens, 2013, Oncogene.

FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer.

Ziqiang Zhu, Hideo Yagita, S. Ambs, 2011, The Journal of clinical investigation.

Immunotherapy-induced CD8+ T cells instigate immune suppression in the tumor.

Ziqiang Zhu, Robin Hallett, Yonghong Wan, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression

A. Perantoni, A. Hurwitz, Kangsun Yun, 2018, PloS one.

An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers.

J. Gillespie, R. Stephens, M. Yi, 2016, Cancer research.

Immune-Suppressive Mechanisms and Cancer: Understanding the Implications, Paradoxes, and Burning Questions

D. Gabrilovich, A. Hurwitz, 2008 .

Tolerization of tumor-specific T cells despite efficient initial priming in a primary murine model of prostate cancer.

N. Greenberg, A. Hurwitz, K. Shafer-Weaver, 2007, The Journal of Immunology.

The influence of IL‐2 family cytokines on activation and function of naturally occurring regulatory T cells

S. Durum, A. Hurwitz, J. Willette-Brown, 2008, Journal of leukocyte biology.

Non-deletional CD8+ T cell self-tolerance permits responsiveness but limits tissue damage

S. Jameson, A. Hurwitz, T. Knutson, 2020, bioRxiv.

High-avidity T cells are preferentially tolerized in the tumor microenvironment.

V. Bronte, V. Singh, A. Hurwitz, 2013, Cancer research.

Stimulation de lymphocytes t contre des auto-antigenes au moyen d'agents bloquants ctla-4

J. Allison, A. Hurwitz, Andrea Vanelsas, 1999 .

Tumor-induced immune suppression : mechanisms and therapeutic reversal

D. Gabrilovich, A. Hurwitz, 2008 .

Immunization with DNA topoisomerase I induces autoimmune responses but not scleroderma-like pathologies in mice.

A. Hurwitz, J. Oppenheim, P. Hu, 2007, The Journal of rheumatology.

Cytotoxic activity of graft-infiltrating lymphocytes correlates with cellular rejection in cardiac transplant patients.

J. Fallon, A. Hurwitz, J. Kurnick, 1991, Human immunology.