A. Habib

发表

Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators

W. Koenig, J. Maclouf, A. Tedgui, 1998, Nature.

Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.

W. Koenig, J. Maclouf, A. Tedgui, 1998, Nature.

Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP

J. Rosa, J. Herbert, P. Savi, 2003, British journal of haematology.

Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis.

C. Patrono, E. Barbarotto, N. Maggiano, 2004, Experimental hematology.

Costimulation of the Gi‐coupled ADP receptor and the Gq‐coupled TXA2 receptor is required for ERK2 activation in collagen‐induced platelet aggregation

M. Bryckaert, J. Rosa, A. Habib, 2004, FEBS letters.

Tyrosine Phosphorylation of Cortactin Associated with Syk Accompanies Thromboxane Analogue-induced Platelet Shape Change*

J. Rosa, J. Maclouf, C. Gallet, 1999, The Journal of Biological Chemistry.

Patient-independent variables affecting the assessment of aspirin responsiveness by serum thromboxane measurement

C. Patrono, F. Veglia, E. Tremoli, 2016, Thrombosis and Haemostasis.

Epidermal-growth-factor receptor and metalloproteinases mediate thromboxane A2-dependent extracellular-signal-regulated kinase activation.

C. Gallet, A. Habib, S. Lévy-Toledano, 2003, The Biochemical journal.

Modulation of COX-2 Expression by Statins in Human Aortic Smooth Muscle Cells

J. Bertoglio, P. Boquet, C. Créminon, 2001, The Journal of Biological Chemistry.

Thrombin induces angiogenesis and vascular endothelial growth factor expression in human endothelial cells: possible relevance to HIF‐1α

A. Habib, M. Lebret, G. Tobelem, 2003, Journal of thrombosis and haemostasis : JTH.

Endothelin‐1 Stimulates Sphingosine Kinase in Human Hepatic Stellate Cells: A Novel Role for Sphingosine‐1‐P as a Mediator of Growth Inhibition

J. Davaille, A. Mallat, T. Levade, 2000, Annals of the New York Academy of Sciences.

The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKC epsilon inhibition.

R. de Caterina, S. Del Turco, B. Weksler, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Cyclooxygenase-2 and synthesis of PGE2 in human bronchial smooth-muscle cells.

J. Maclouf, A. Sala, D. Boraschi, 1997, American journal of respiratory and critical care medicine.

Directed vascular expression of the thromboxane A2 receptor results in intrauterine growth retardation

G. FitzGerald, J. Strauss, B. Rocca, 2000, Nature Medicine.

Plasma Kallikrein as a Modulator of Liver Injury/Remodeling

A. Jaffa, E. Hamade, A. Habib, 2021, Frontiers in Pharmacology.

Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance".

F. Santilli, G. Davı̀, C. Patrono, 2009, Journal of the American College of Cardiology.

In Vivo Platelet Activation and Aspirin Responsiveness in Type 1 Diabetes

C. Patrono, E. Tremoli, F. Zaccardi, 2015, Diabetes.

Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2.

J. Maclouf, J. Grassi, C. Créminon, 1993, The Journal of biological chemistry.

gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect

N. El-Hachem, A. Hachem, B. Badran, 2019, BMC Chemistry.

Cyclooxygenase Involvement in Thromboxane-Dependent Contraction in Rat Mesenteric Resistance Arteries

B. Lévy, D. Henrion, A. Habib, 2004, Hypertension.

Cyclooxygenases-1 and −2 of Endothelial Cells Utilize Exogenous or Endogenous Arachidonic Acid for Transcellular Production of Thromboxane (*)

J. Maclouf, A. Habib, S. Levy‐toledano, 1996, The Journal of Biological Chemistry.

Regulation of the expression of cyclooxygenase-2 by nitric oxide in rat peritoneal macrophages.

J. Maclouf, A. Tedgui, C. Créminon, 1997, Journal of immunology.

Elevated levels of circulating procoagulant microparticles in patients with β-thalassemia intermedia

J. Freyssinet, A. Taher, A. Habib, 2008, Haematologica.

p38 Mitogen-Activated Protein Kinase Activation Is Required for Thromboxane- Induced Contraction in Perfused and Pressurized Rat Mesenteric Resistance Arteries

B. Lévy, J. Maclouf, D. Henrion, 2002, Journal of Vascular Research.

Rapid, Agonist-dependent Phosphorylation in Vivo of Human Thromboxane Receptor Isoforms

G. FitzGerald, J. Maclouf, C. Créminon, 1997, The Journal of Biological Chemistry.

Molecular pharmacology of isoprostanes in vascular smooth muscle.

K. Badr, A. Habib, 2004, Chemistry and physics of lipids.

Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2.

A. Mallat, S. Lotersztajn, J. Maclouf, 1998, The Journal of biological chemistry.

Phosphorylation of the Thromboxane Receptor α, the Predominant Isoform Expressed in Human Platelets*

G. FitzGerald, J. Maclouf, A. Habib, 1999, The Journal of Biological Chemistry.

The Analysis of Eicosanoids Derived From Platelets

J. Maclouf, A. Habib, 1995 .

Enhanced expression of haem oxygenase‐1 by nitric oxide and antiinflammatory drugs in NIH 3T3 fibroblasts

M. Alcaraz, J. Maclouf, C. Créminon, 2000, British journal of pharmacology.

Modulation of COX‐2 expression by statins in human monocytic cells

K. Badr, J. Bertoglio, A. Habib, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

J. Wan, H. Guillou, B. Cravatt, 2018, Gut.

Modulation of proteomic and inflammatory signals by Bradykinin in podocytes

Y. Mechref, F. Kobeissy, A. Jaffa, 2020, Journal of advanced research.

Enzyme immunometric assay for endothelin using tandem monoclonal antibodies.

C. Patrono, J. Maclouf, J. Grassi, 1993, Journal of immunological methods.

Antiproliferative Properties of Sphingosine 1-Phosphate in Human Hepatic Myofibroblasts

J. Davaille, Liying Li, A. Mallat, 2000, The Journal of Biological Chemistry.

Prostaglandin E2 Differentially Modulates Human Platelet Function through the Prostanoid EP2 and EP3 Receptors

S. Rutella, C. Patrono, F. Ranelletti, 2011, Journal of Pharmacology and Experimental Therapeutics.

Statins Modulate Cyclooxygenase‐2 and Microsomal Prostaglandin E Synthase‐1 in Human Hepatic Myofibroblasts

S. Lotersztajn, A. Abdul-Sater, C. Créminon, 2016, Journal of cellular biochemistry.

Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo.

A. Eid, A. Hachem, B. Badran, 2015, European journal of pharmacology.

Comparison of leukotriene A4 metabolism into leukotriene C4 by human platelets and endothelial cells.

J. Maclouf, A. Habib, 1992, Archives of biochemistry and biophysics.

thrombocythemia is explained by accelerated renewal of the drug target Aspirin-insensitive thromboxane biosynthesis in essential

C. Patrono, F. Zaccardi, B. Rocca, 2013 .

Heme oxygenase-1—Dependent anti-inflammatory effects of atorvastatin in zymosan-injected subcutaneous air pouch in mice

A. Jaffa, B. Badran, M. Mrad, 2019, PloS one.

Inhibition of cyclooxygenase activity in human endothelial cells by homocysteine.

J. Maclouf, A. Habib, I. Quéré, 1995, Advances in prostaglandin, thromboxane, and leukotriene research.

Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris

F. Kobeissy, A. Jaffa, A. Eid, 2021, Frontiers in Pharmacology.

Cyclooxygenase-1, but not -2, is upregulated in NB4 leukemic cells and human primary promyelocytic blasts during differentiation

N. Maggiano, F. Ranelletti, G. Ciabattoni, 2004, Leukemia.

Differential measurement of constitutive (COX-1) and inducible (COX-2) cyclooxygenase expression in human umbilical vein endothelial cells using specific immunometric enzyme immunoassays.

J. Maclouf, J. Grassi, C. Créminon, 1995, Biochimica et biophysica acta.

Immunological studies of human constitutive cyclooxygenase (COX-1) using enzyme immunometric assay.

J. Maclouf, J. Grassi, C. Créminon, 1995, Biochimica et biophysica acta.

Distinct expression of cyclooxygenase‐1 and ‐2 in the human thymus

A. Fattorossi, N. Maggiano, F. Ranelletti, 2002, European journal of immunology.

Differential Signaling by the Thromboxane Receptor Isoforms via the Novel GTP-binding Protein, Gh *

G. FitzGerald, A. Habib, R. Vezza, 1999, The Journal of Biological Chemistry.

Involvement of tyrosine kinases in the induction of cyclo-oxygenase-2 in human endothelial cells.

J. Maclouf, A. Habib, S. Levy‐toledano, 1995, The Biochemical journal.

Mutational Analysis of the Highly Conserved ERY Motif of the Thromboxane A2 Receptor: Alternative Role in G Protein-Coupled Receptor Signaling

M. Parenti, A. Habib, Luca Crimaldi, 2004, Molecular Pharmacology.

Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation.

A. Habib, M. Accomazzo, G. Rovati, 2003, European journal of pharmacology.

Role of NF-κB in the Antiproliferative Effect of Endothelin-1 and Tumor Necrosis Factor-α in Human Hepatic Stellate Cells

A. Mallat, S. Lotersztajn, J. Maclouf, 1998, The Journal of Biological Chemistry.

Heteromerization fingerprints between bradykinin B2 and thromboxane TP receptors in native cells

A. Jaffa, F. Ziyadeh, A. Habib, 2019, PloS one.

Cyclooxygenases in human and mouse skin and cultured human keratinocytes: association of COX-2 expression with human keratinocyte differentiation.

J. Maclouf, M. Goldyne, A. Habib, 1996, Experimental cell research.

Induction of cyclo‐oxygenase‐2 in human endothelial cells by SIN‐1 in the absence of prostaglandin production

J. Maclouf, C. Créminon, A. Habib, 2001, British journal of pharmacology.

Thromboxane-induced ERK phosphorylation in human aortic smooth muscle cells.

C. Gallet, A. Habib, S. Blaie, 2003, Advances in experimental medicine and biology.

Prognostic significance of cyclooxygenase‐2 in laryngeal squamous cell carcinoma

N. Maggiano, F. Ranelletti, G. Almadori, 2001, International journal of cancer.

Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target.

C. Patrono, F. Zaccardi, B. Rocca, 2012, Blood.

Mutational Analysis of the Highly Conserved ERY Motif of the Thromboxane A 2 Receptor: Alternative Role in GPCR Signaling

M. Parenti, A. Habib, Luca Crimaldi, 2004 .

Human Septic Myopathy: Induction of Cyclooxygenase, Heme Oxygenase and Activation of the Ubiquitin Proteolytic Pathway

A. Mebazaa, M. Singer, D. Brealey, 2004, Anesthesiology.

Heme oxygenase-1 induction by nitric oxide in RAW 264.7 macrophages is upregulated by a cyclo-oxygenase-2 inhibitor.

M. Alcaraz, J. Maclouf, C. Créminon, 2001, Biochimica et biophysica acta.

Pathophysiology of Thrombosis in Peripheral Artery Disease.

B. Rocca, A. Habib, G. Petrucci, 2019, Current vascular pharmacology.

Increased Expression of Inducible Cyclooxygenase-2 in Human Endothelial Cells by Antiphospholipid Antibodies

J. Maclouf, L. Carreras, M. Martinuzzo, 1995, Thrombosis and Haemostasis.

The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKCε inhibition

R. de Caterina, B. Weksler, G. Lazzerini, 2006, Proceedings of the National Academy of Sciences.

Arsenic trioxide inhibits ATRA-induced prostaglandin E2 and cyclooxygenase-1 in NB4 cells, a model of acute promyelocytic leukemia

A. Bazarbachi, E. Hamade, A. Habib, 2008, Leukemia.

The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy.

G. Davı̀, C. Patrono, F. Ranelletti, 2010, Blood.

Cytokine imbalance in acute coronary syndrome.

K. Badr, A. Habib, S. Alam, 2004, Current opinion in pharmacology.

Aspirin alters arterial function in patients with chronic heart failure treated with ACE inhibitors: a dose‐mediated deleterious effect

A. Cohen-Solal, G. Jondeau, B. Lévy, 2003, European journal of heart failure.

Platelet thromboxane inhibition by low‐dose aspirin in polycythemia vera: Ex vivo and in vivo measurements and in silico simulation

C. Patrono, E. Tremoli, B. Rocca, 2022, Clinical and translational science.

Circulating Microparticles in Lebanese Patients with beta-Thalassemia Intermedia.

J. Freyssinet, A. Taher, A. Habib, 2006 .

Role of Nitric Oxide and CCAAT/Enhancer-Binding Protein Transcription Factor in Statin-Dependent Induction of Heme Oxygenase-1 in Mouse Macrophages

J. Alam, M. Mrad, E. Hamade, 2013, PloS one.

Tobacco cigarette smoking exacerbates aortic calcification in an early stage of myocardial infarction in a female mouse model

F. Kobeissy, F. Zouein, E. Hamade, 2020, Journal of cellular physiology.

Immunolocalization of P2Y1 and TPα Receptors in Platelets Showed a Major Pool Associated with the Membranes of α-Granules and the Open Canalicular System

P. Nurden, P. Conley, A. Nurden, 2003 .

Characterization and assessment of potential microRNAs involved in phosphate‐induced aortic calcification

F. Kobeissy, A. Zeidan, Najwa Skafi, 2018, Journal of cellular physiology.

Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption[S]

H. Scharnagl, M. Trauner, R. Zimmermann, 2019, Journal of Lipid Research.

Platelet-derived Growth Factor-BB and Thrombin Generate Positive and Negative Signals for Human Hepatic Stellate Cell Proliferation

A. Mallat, S. Lotersztajn, J. Maclouf, 1998, The Journal of Biological Chemistry.

Cyclo‐oxygenase‐1 and −2 contribution to endothelial dysfunction in ageing

A. Habib, C. Boulanger, C. Heymes, 2000, British journal of pharmacology.

Cyclooxygenase-2 Glycosylation Is Affected by Peroxynitrite in Endothelial Cells: Impact on Enzyme Activity and Degradation

G. Aldini, C. Banfi, A. Altomare, 2021, Antioxidants.

Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis

H. Scharnagl, M. Trauner, R. Zimmermann, 2019, Hepatology.

Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents

A. Hachem, B. Badran, R. Grée, 2023, International journal of molecular sciences.

New analogues of 13-hydroxyocatdecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity

N. El-Hachem, A. Hachem, C. Créminon, 2012, Chemistry Central Journal.

Regulation of Cyclooxygenases by Protein Kinase C

G. FitzGerald, J. Lawson, A. Habib, 1996, The Journal of Biological Chemistry.

Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation.

G. FitzGerald, J. Lawson, S. Kapoor, 2000, The Journal of clinical investigation.

Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo.

A. Eid, A. Hachem, B. Badran, 2015, European journal of pharmacology.

Statins modulate transcriptional activity of heme‐oxygenase‐1 promoter in NIH 3T3 Cells

A. Eid, J. Alam, M. Mrad, 2012, Journal of cellular biochemistry.

Epidermal-growth-factor receptor and metalloproteinases mediate thromboxane A2-dependent extracellular-signal-regulated kinase activation.

C. Gallet, A. Habib, S. Blaie, 2003, The Biochemical journal.

Human Septic Myopathy: Induction of Cyclooxygenase, Heme Oxygenase and Activation of the Ubiquitin Proteolytic Pathway

A. Mebazaa, M. Singer, D. Brealey, 2004, Anesthesiology.