S. Machin

发表

G. Lowe, S. Kitchen, I. Mackie, 2003, British journal of haematology.

Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies

F. Peyvandi, R. Liesner, B. Hunt, 2012, British journal of haematology.

Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial

D. Isenberg, C. Doré, M. Khamashta, 2016, The Lancet. Haematology.

Development of an automated malaria discriminant factor using VCS technology.

Ilse Aucamp, S. Machin, C. Briggs, 2006, American journal of clinical pathology.

Vascular Endothelium in Hemostasis and Thrombosis

S. Machin, 1988 .

Mean platelet volume: a quick, easy determinant of thrombotic risk?

S. Machin, C. Briggs, 2010, Journal of thrombosis and haemostasis : JTH.

THROMBOXANE SYNTHETASE INHIBITION AS ANTITHROMBOTIC STRATEGY

J. Vermylen, M. Verstraete, L. Carreras, 1981, The Lancet.

Guidelines for the laboratory investigation of heritable disorders of platelet function

Paul J. Harrison, A. Mumford, R. Liesner, 2011, British journal of haematology.

International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of ADAMTS13

S. Nair, J. K. Kremer Hovinga, I. Mackie, 2020, International journal of laboratory hematology.

Clinical Practice Guidelines for the management of atypical Haemolytic Uraemic Syndrome in the United Kingdom

S. Wigmore, S. Machin, T. Goodship, 2010, British journal of haematology.

Activation of platelets in whole blood by recombinant factor VIIa by a thrombin‐dependent mechanism

R. Liesner, I. Mackie, S. Machin, 2003, British journal of haematology.

Guidelines for Testing and Revised Criteria for Lupus Anticoagulants

S. Machin, D. Triplett, T. Exner, 1991, Thrombosis and Haemostasis.

Assessment of the antiplatelet effects of low to medium dose aspirin in the early and late phases after ischaemic stroke and TIA

P. Sidhu, M. Brown, I. Mackie, 2005, Platelets.

A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura.

J. Cavenagh, H. Cohen, B. Hunt, 2011, Blood.

Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS‐13

J. Cavenagh, H. Cohen, S. Killick, 2007, British journal of haematology.

Hextend (R), a physiologically balanced plasma expander for large volume use in major surgery: A randomized phase III clinical trial

B. Phillips-Bute, E. Bennett-Guerrero, T. Gan, 1999 .

Hextend, a physiologically balanced plasma expander for large volume use in major surgery: a randomized phase III clinical trial. Hextend Study Group.

P. Glass, B. Phillips-Bute, E. Bennett-Guerrero, 1999, Anesthesia and analgesia.

Hextend[registered sign], a Physiologically Balanced Plasma Expander for Large Volume Use in Major Surgery: A Randomized Phase III Clinical Trial

B. Phillips-Bute, E. Bennett-Guerrero, T. Gan, 1999 .

Hydroxyethyl Starch in Balanced Electrolyte Solution (Hextend®)—Pharmacokinetic and Pharmacodynamic Profiles in Healthy Volunteers

E. Bennett-Guerrero, T. Gan, S. Machin, 2002, Anesthesia and analgesia.

Rivaroxaban and warfarin achieve effective anticoagulation, as assessed by inhibition of TG and in-vivo markers of coagulation activation, in patients with venous thromboembolism.

H. Cohen, S. Machin, I. Mackie, 2015, Thrombosis research.

Anti‐protein C antibodies are associated with resistance to endogenous protein C activation and a severe thrombotic phenotype in antiphospholipid syndrome

H. Cohen, S. Machin, I. Mackie, 2014, Journal of thrombosis and haemostasis : JTH.

Determination of APTT factor sensitivity – the misguiding guideline

S. Kitchen, S. Machin, I. Mackie, 2013, International journal of laboratory hematology.

Persistent high factor VIII activity leading to increased thrombin generation - a prospective cohort study.

S. Machin, I. Mackie, A. Lawrie, 2012, Thrombosis research.

The effect of total hip/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters.

F. Haddad, L. Green, I. Mackie, 2012, Thrombosis research.

Development and application of an automated chromogenic thrombin generation assay that is sensitive to defects in the protein C pathway.

L. Green, H. Cohen, I. Mackie, 2012, Thrombosis research.

The impact of elective knee/hip replacement surgery and thromboprophylaxis with rivaroxaban or dalteparin on thrombin generation

F. Hossain, Shelain Patel, F. Haddad, 2010, British journal of haematology.

New antiplatelet drugs.

S. Machin, J. Joseph, Samuel J. Machin, 1997, Blood reviews.

Hydroxyethyl starch: an alternative to plasma for postoperative volume expansion after cardiac surgery

T. Treasure, E. Macintyre, I. Mackie, 1988, The British journal of surgery.

New Red Cell Parameters on the Sysmex XE-2100TM as Potential Markers of Functional Iron Deficiency

S. Machin, R. Rogers, C. Briggs, 2001, Transfusion Medicine and Hemotherapy.

Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: Report of a Task Force at the 13th International Congress on Antiphospholipid Antibodies

M. Khamashta, G. Ruiz-Irastorza, M. Crowther, 2011, Lupus.

Detection of acquired resistance to activated protein C associated with antiphospholipid antibodies using a novel clotting assay

H. Cohen, I. Mackie, S. Machin, 2006, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Thrombin generation and factor X assays for the assessment of warfarin anticoagulation in thrombotic antiphospholipid syndrome.

H. Cohen, I. Mackie, S. Machin, 2015, Thrombosis research.

ABC of clinical haematology: Platelet disorders

R. Liesner, S. Machin, 1997, BMJ.

Pregnancy loss, tissue factor pathway inhibitor deficiency and resistance to activated protein C

S. Austin, H. Cohen, I. Mackie, 2006, Journal of thrombosis and haemostasis : JTH.

The impact of oral anticoagulant therapy, factor VIII level and quality of factor V-deficient plasma on three commercial methods for activated protein C resistance

S. Machin, I. Mackie, P. Harrison, 2001, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Guidelines On The Investigation and Management Of The Antiphospholipid Syndrome

H. Cohen, M. Greaves, I. Mackie, 2000, British journal of haematology.

ARTERIAL THROMBOSIS, INTRAUTERINE DEATH AND "LUPUS" ANTICOAGULANT: DETECTION OF IMMUNOGLOBULIN INTERFERING WITH PROSTACYCLIN FORMATION

J. Vermylen, L. Carreras, B. Spitz, 1981, The Lancet.

The “Primary” Antiphospholipid Syndrome: Major Clinical and Serological Features

G. Hughes, M. Khamashta, R. Derksen, 1989, Medicine.

A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications.

C. Harrison, D. Linch, S. Machin, 1999, Blood.

Tissue factor pathway inhibitor antigen and activity in 96 patients receiving heparin for cardiopulmonary bypass.

R. Cardigan, M. Grocott, M. Mythen, 2002, Journal of cardiothoracic and vascular anesthesia.

Lack of association of β2‐glycoprotein I polymorphisms Val247Leu and Trp316Ser with antiphospholipid antibodies in patients with thrombosis and pregnancy complications

S. Humphries, H. Cohen, I. Mackie, 2003, British journal of haematology.

Continuous venovenous haemofiltration using polyacrylonitrile filters does not activate contact system and intrinsic coagulation pathways

R. Cardigan, S. Machin, I. Mackie, 1997, Intensive Care Medicine.

Platelet c‐mpl expression is dysregulated in patients with essential thrombocythaemia but this is not of diagnostic value

A. Mire-Sluis, C. Harrison, D. Linch, 1999, British journal of haematology.

The expression of prion protein (PrPC) in the megakaryocyte lineage

Pille Harrison, A. Pizzey, I. Mackie, 2005, Journal of thrombosis and haemostasis : JTH.

Measuring thrombin generation based sensitivity to activated protein C using an automated coagulometer (ACL 9000)

I. Mackie, S. Machin, C. Gardiner, 2008, International journal of laboratory hematology.

Initial experience from a double‐blind, placebo‐controlled, clinical outcome study of ARC1779 in patients with thrombotic thrombocytopenic purpura

B. Lämmle, P. Mannucci, B. Jilma, 2012, American journal of hematology.

Measurement of CD4+ T cells in point-of-care settings with the Sysmex pocH-100i haematological analyser

S. Machin, R. Hinzmann, C. Briggs, 2009, International journal of laboratory hematology.

Platelet impedance aggregation in whole blood and its inhibition by antiplatelet drugs.

I. Mackie, S. Machin, R. Jones, 1984, Journal of clinical pathology.

The VWF/ADAMTS13 axis in the antiphospholipid syndrome: ADAMTS13 antibodies and ADAMTS13 dysfunction

S. Austin, H. Cohen, I. Mackie, 2008, British journal of haematology.

Measurement of the antiplatelet effects of aspirin in cerebrovascular disease.

M. Brown, S. Machin, D. McCabe, 2004, Stroke.

Performance evaluation of a new small-volume coagulation monitor: the SmartCheck INR system.

H. Cohen, I. Mackie, S. Machin, 2008, American journal of clinical pathology.

A randomised controlled trial of patient self management of oral anticoagulation compared with patient self-testing.

H. Cohen, I. Mackie, S. Machin, 2005 .

Platelet degranulation and monocyte–platelet complex formation are increased in the acute and convalescent phases after ischaemic stroke or transient ischaemic attack

P. Sidhu, M. Brown, I. Mackie, 2004, British journal of haematology.

CIGARETTE SMOKING AND PLATELET ADHESION

N. Woolf, S. Machin, R. Pittilo, 1983, The Lancet.

Antithrombotic treatment for stroke associated with antiphospholipid antibodies

H. Cohen, S. Machin, Deepa R Jayakody Arachchillage, 2014, Expert review of hematology.

Stomatocytic haemolysis and macrothrombocytopenia (Mediterranean stomatocytosis/macrothrombocytopenia) is the haematological presentation of phytosterolaemia

P. Gasparini, M. Carella, A. Iolascon, 2005, British journal of haematology.

Desirability and problems of early diagnosis of essential thrombocythaemia

C. Harrison, D. Linch, S. Machin, 1998, The Lancet.

Diagnosis and management of non-criteria obstetric antiphospholipid syndrome

H. Cohen, I. Mackie, S. Machin, 2014, Thrombosis and Haemostasis.

Complement C5-inhibitor rEV576 (coversin) ameliorates in-vivo effects of antiphospholipid antibodies

A. Brasier, H. Cohen, S. Machin, 2014, Lupus.

The anticardiolipin assay is required for sensitive screening for antiphospholipid antibodies

H. Cohen, I. Mackie, S. Machin, 2004, Journal of thrombosis and haemostasis : JTH.

Lassa fever encephalopathy: clinical and laboratory findings.

J. McCormick, S. Fisher-Hoch, S. Machin, 1992, The Journal of tropical medicine and hygiene.

Fluctuations in levels of antiphospholipid antibodies and increased coagulation activation markers in normal andheparin-treated antiphospholipid syndrome pregnancies

J. Kingdom, S. Quenby, S. Donohoe, 2002, Lupus.

Routine measurement of fibrinogen concentration.

I. Mackie, S. Machin, 1993, BMJ.

Mechanisms of Haemostasis

S. Machin, 1992 .

Circulating reticulated platelets in the early and late phases after ischaemic stroke and transient ischaemic attack

P. Sidhu, M. Brown, S. Machin, 2004, British journal of haematology.

Platelets: the few, the young, and the active.

S. Machin, C. Briggs, C. D'Souza, 2015, Clinics in laboratory medicine.

XR5118, a novel modulator of plasminogen activator inhibitor-1 (PAI-1), increases endogenous tPA activity in the rat

P. Charlton, S. Machin, P. Bevan, 1997 .

Contrast, coagulation, and fibrinolysis.

I. Mackie, S. Machin, S. Machin, 1986, Investigative radiology.

The Effect of Clinical Prostacyclin Infusions in Advanced Arterial Disease on Platelet Function and Plasma 6‐keto PGF1α Levels

J. Vermylen, S. Machin, S. Machin, 1981, British journal of haematology.

ALTERED PLATELET FUNCTION IN PATIENTS ON CONTINUOUS INFUSIONS OF EPOPROSTENOL

S. Machin, D. Yardumian, 1984, The Lancet.

Endothelial cells express normal cellular prion protein

I. Macgregor, I. Mackie, S. Machin, 2003, British journal of haematology.

The expression of prion protein by endothelial cells: a source of the plasma form of prion protein?

I. Macgregor, I. Mackie, S. Machin, 2002, British journal of haematology.

Life‐threatening thrombotic and haemorrhagic problems associated with silent myeloproliferative disorders

S. Machin, H. Walker, K. Patterson, 1993, British journal of haematology.

Familial occurrence of the antiphospholipid syndrome.

I. Mackie, S. Machin, F. Matthey, 1989, Journal of clinical pathology.

Prion protein in patients with renal failure

I. Macgregor, I. Mackie, S. Machin, 2006, Transfusion medicine.

Guidelines on the diagnosis and management of the thrombotic microangiopathic haemolytic anaemias

B. Hunt, S. Machin, P. Rose, 2003, British journal of haematology.

New quantitative parameters on a recently introduced automated blood cell counter--the XE 2100.

J. Staves, S. Machin, C. Briggs, 2000, Clinical and laboratory haematology.

B cell activating factor is elevated in acute idiopathic thrombotic thrombocytopenic purpura

M. Scully, I. Mackie, S. Machin, 2011, British journal of haematology.

Laboratory investigation of platelet function: a review of methodology.

S. Machin, I. Mackie, D. Yardumian, 1986, Journal of clinical pathology.

Immature platelet fraction measurement: a future guide to platelet transfusion requirement after haematopoietic stem cell transplantation

D. Hart, S. Machin, C. Briggs, 2006, Transfusion medicine.

Assessment of an immature platelet fraction (IPF) in peripheral thrombocytopenia

D. Hart, S. Machin, C. Briggs, 2004, British journal of haematology.

An evaluation of rapid D‐dimer assays for the exclusion of deep vein thrombosis

I. Mackie, S. Machin, C. Gardiner, 2005, British journal of haematology.

Falsely elevated D‐dimer results in a healthy patient on account of heterophiletul antibodies

A. Sheldrake, I. Mackie, S. Machin, 2003, British journal of haematology.

Use of the complement inhibitor Coversin to treat HSCT-associated TMA.

P. Veys, P. Amrolia, M. Nunn, 2017, Blood advances.

Cigarette smoking and platelet adhesion

N. Woolf, I. Mackie, S. Machin, 1984, Lancet.

Blockade of the human platelet GPIIb/IIIa receptor by a murine monoclonal antibody Fab fragment (7E3): Potent dose-dependent inhibition of platelet function

H. Weisman, R. Jordan, R. Senior, 1995, Cardiovascular Drugs and Therapy.

Plasma from patients with severe Lassa fever profoundly modulates f‐met‐leu‐phe induced superoxide generation in neutrophils

J. Gribben, J. McCormick, S. Fisher-Hoch, 1989, British journal of haematology.

Abstract

A. Pizzey, Mackie, S. Machin, 2003 .

Disturbances of haemostasis in surgical and critically ill patients

S. Machin, F. Matthey, 1988 .

Activation of the tissue factor pathway occurs during continuous venovenous hemofiltration.

R. Cardigan, H. McGloin, S. Machin, 1999, Kidney international.

Endothelial dysfunction in critically ill patients: the effect of haemofiltration

R. Cardigan, H. McGloin, S. Machin, 1998, Intensive Care Medicine.

Pharmacokinetics and pharmacodynamics of Ro 44-3888 after single ascending oral doses of sibrafiban, an oral platelet aggregation inhibitor, in healthy male volunteers.

I. Mackie, S. Machin, M. Zell, 1999, British journal of clinical pharmacology.

Anti‐prothrombin antibodies: assay conditions and clinical associations in the anti‐phospholipid syndrome

D. Isenberg, I. Mackie, S. Machin, 2001, British journal of haematology.

Guideline GUIDELINES ON FIBRINOGEN ASSAYS

G. Lowe, S. Kitchen, I. Mackie, 2022 .

Thrombotic thrombocytopenic purpura associated with statin therapy.

M. Scully, S. Machin, M. Thomas, 2011, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Comparative sensitivity of commonly used thromboplastins to ex vivo therapeutic rivaroxaban levels

H. Cohen, I. Mackie, S. Machin, 2014, Thrombosis and Haemostasis.

A comparative evaluation of the CN‐6000 haemostasis analyser using coagulation, amidolytic, immuno‐turbidometric and light transmission aggregometry assays

I. Mackie, S. Machin, C. Gardiner, 2020, International journal of laboratory hematology.

An update on the pathogenesis and management of acquired thrombotic thrombocytopenic purpura.

S. Machin, H. Yarranton, 2003, Current opinion in neurology.

Antiphospholipid Syndrome Clinical Research Task Force Report

R. Levy, T. Ortel, M. Lockshin, 2011, Lupus.

Self-monitoring of oral anticoagulation: does it work outside trial conditions?

H. Cohen, S. Machin, J. Hills, 2009, Journal of Clinical Pathology.

International Council for Standardization in Haematology (ICSH) recommendations for "surrogate reference" method for the packed cell volume.

N. Tatsumi, S. Lewis, L. Van Hove, 2003, Laboratory hematology : official publication of the International Society for Laboratory Hematology.

Anti‐tissue factor pathway inhibitor activity in patients with primary antiphospholipid syndrome

I. Mackie, S. Machin, M. Adams, 2001, British journal of haematology.

The automation of routine light transmission platelet aggregation

S. Machin, I. Mackie, A. Lawrie, 2013, International journal of laboratory hematology.

Performance evaluation of the Sysmex haematology XN modular system

S. Machin, C. Briggs, I. Longair, 2012, Journal of Clinical Pathology.

Platelet Function in Diabetes Mellitus - Studies of Platelet Aggregation in Whole Blood

D. Betteridge, S. Machin, R. Jones, 1983 .

The haemostatic function of the vascular endothelial cell

S. Machin, H. Bull, 1987, Blut.

Human immunodeficiency virus associated thrombotic thrombocytopenic purpura – favourable outcome with plasma exchange and prompt initiation of highly active antiretroviral therapy

T. Baglin, D. Hart, Robert F Miller, 2011, British journal of haematology.

Coagulation factor levels in cryosupernatant prepared from plasma treated with amotosalen hydrochloride (S‐59) and ultraviolet A light

L. Corash, I. Mackie, S. Machin, 2005, Transfusion.

Comparison of von Willebrand factor antigen, von Willebrand factor‐cleaving protease and protein S in blood components used for treatment of thrombotic thrombocytopenic purpura

I. Mackie, S. Machin, H. Yarranton, 2004, Transfusion medicine.

Venous thromboembolism associated with the management of acute thrombotic thrombocytopenic purpura

H. Cohen, S. Pavord, S. Machin, 2003, British journal of haematology.

Successful treatment of Raynaud's syndrome with Iloprost, a chemically stable prostacyclin analogue.

D. Isenberg, M. Snaith, S. Machin, 1988, British journal of rheumatology.

Persistent decreased fibrinolytic activity in cyclosporin-treated renal allograft recipients

H. Cohen, S. Machin, G. Neild, 1988 .

Newer Pharmacological Agents

S. Machin, A. Yardumian, 1988 .

Familial lupus anticoagulants

I. Mackie, S. Machin, C. Colaço, 1987, British journal of haematology.

Automated Platelet Analysis

S. Machin, C. Briggs, 2012 .

Acquired, noncongenital thrombotic thrombocytopenic purpura in children and adolescents: clinical management and the use of ADAMTS 13 assays

R. Liesner, M. Scully, S. Machin, 2010, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Current understanding of the pathophysiology of thrombotic thrombocytopenic purpura

S. Machin, S. Allford, 2000, Journal of clinical pathology.

Demonstration of viraemia patterns in haemophiliacs treated with hepatitis-C-virus-contaminated factor VIII concentrates

R. Tedder, J. Garson, M. Makris, 1990, The Lancet.

Increased circulating platelet–leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis

D. Isenberg, Pille Harrison, I. Mackie, 2001, British journal of haematology.

Serum from patients with Raynaud's phenomenon inhibits prostacyclin production.

S. Machin, M. Rustin, P. Dowd, 1987, The Journal of investigative dermatology.

Degradation of two novel congenital TTP ADAMTS13 mutants by the cell proteasome prevents ADAMTS13 secretion.

F. Peyvandi, I. Garagiola, I. Mackie, 2016, Thrombosis research.

Title : Degradation of two novel congenital TTP ADAMTS 13 mutants by the cell proteasome prevents ADAMTS 13 secretion

Mackie, F. Peyvandi, I. Garagiola, 2016 .

A plasma inhibitor of platelet aggregation in patients with Lassa fever

J. McCormick, S. Fisher-Hoch, I. Mackie, 1989, British journal of haematology.

CONCOMITANT MYELODYSPLASTIC SYNDROME AND CHRONIC MYELOID LEUKAEMIA: TREATMENT OUTCOMES WITH IMATINIB MESYLATE

I. Macgregor, I. Mackie, S. Machin, 2003 .

Hextend T , a Physiologically Balanced Plasma Expander for Large Volume Use in Major Surgery: A Randomized Phase III Clinical Trial the Hextend t Study

B. Phillips-Bute, E. Bennett-Guerrero, T. Gan, 1999 .

Multiple organ failure

A. Webb, A. Kotanidou, C. Zauner, 1992, Intensive Care Medicine.

Clopidogrel: a novel antiplatelet agent.

S. Machin, S. D'sa, S. D’Sa, 1999, Hospital medicine.

Antiphospholipid syndrome A common cause of thrombosis

S. Machin, 2006 .

Abnormal prostacyclin metabolism in the hemolytic uremic syndrome: equivocal effect of prostacyclin infusions.

J. Vermylen, S. Machin, W. Proesmans, 1982, Clinical nephrology.

PLASMA 6-KETO-PGF1α LEVELS AFTER PLASMA EXCHANGE IN THROMBOTIC THROMBOCYTOPENIC PURPURA

J. Vermylen, S. Machin, G. Defreyn, 1980, The Lancet.

Evaluation of the Sysmex XN‐550, a Novel Compact Haematology analyser from the XN‐L® series, compared to the XN‐20 system

I. Mackie, S. Machin, A. Mellick, 2017, International journal of laboratory hematology.

Successful management of pregnancy in women with a history of thrombotic thrombocytopaenic purpura

Richard S. Lee, H. Cohen, M. Scully, 2006, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

THROMBOTIC THROMBOCYTOPENIC PURPURA

S. Machin, 1984 .

Cyclophosphamide for chronic relapsing thrombotic thrombocytopenic purpura

S. Machin, D. Cummins, J. Bird, 1990, The Lancet.

Antibiotic treatment and associated prolonged prothrombin time.

K. Williams, R. Bax, S. Machin, 1991, Journal of clinical pathology.

Explorer Antibiotic treatment and associated prolonged prothrombin time

K. Williams, R. Bax, S. Machin, 2022 .

Assessment of Actin FS and Actin FSL sensitivity to specific clotting factor deficiencies.

S. Kitchen, F. Preston, S. Machin, 1998, Clinical and laboratory haematology.

von Willebrand factor‐cleaving protease activity in congenital thrombotic thrombocytopenic purpura

R. Liesner, I. Mackie, S. Machin, 2000, British journal of haematology.

A plasma factor in uraemia which stimulates prostacyclin release from cultured endothelial cells.

J. Vermylen, S. Machin, G. Defreyn, 1980, Thrombosis research.

Disorders of Haemostasis

S. Machin, F. Matthey, 1983 .

The haemostatic effects of hydroxyethyl starch (HES) used as a volume expander

E. Macintyre, I. Mackie, S. Machin, 2004, Intensive Care Medicine.

Discrepancies between ADAMTS13 activity assays in patients with thrombotic microangiopathies

F. Peyvandi, R. Liesner, M. Scully, 2013, Thrombosis and Haemostasis.

Point-of-Care Testing in Hemostasis

Chris Gardiner, Samuel J. Machin, Ian J. Mackie, 2009 .

Impact of immunological platelet counting (by the platelet/RBC ratio) on haematological practice

Paul J. Harrison, M. Murphy, S. Machin, 2005, Cytometry. Part B, Clinical cytometry.

Prolonged post-operative bleeding due to an acquired von Willebrand syndrome.

S. Machin, S. Kinsey, K. Ryder, 1987, Postgraduate medical journal.

THROMBOSIS AND FACTOR-IX CONCENTRATES

B. R. Miller, S. Machin, 1978, The Lancet.

WET HEATING FOR SAFER FACTOR VIII CONCENTRATE?

P. Kernoff, F. Preston, S. Machin, 1985, The Lancet.

A comparative evaluation of a new automated assay for von Willebrand factor activity

F. Peyvandi, I. Mackie, S. Machin, 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

In vitro characterizations of the first therapeutic factor V concentrate

F. Peyvandi, I. Mackie, S. Machin, 2014 .

Cutaneous gangrene with hyperparathyroidism

S. Machin, J. Miller, P. Dowd, 1988, Clinical and experimental dermatology.

Comparison of glycocalicin, thrombopoietin and reticulated platelet measurement as markers of platelet turnover in HIV+ samples

Pille Harrison, I. Mackie, S. Machin, 2001, Platelets.

Electrokinetic behaviour and surface sialic acid status of blood platelets in essential thrombocythaemia (ET)

S. Machin, N. Crawford, M. Crook, 1992, European journal of haematology.

Electrokinetic properties and surface membrane sialic acid status of platelets in idiopathic thrombocytopenic purpura (ITP)

S. Machin, N. Crawford, M. Crook, 1991, British journal of haematology.

Measurement of Platelet Aggregation in Diabetics using the New Electronic Platelet Aggregometer

D. Betteridge, S. Machin, S. Machin, 1985, Diabetic medicine : a journal of the British Diabetic Association.

Multiple transient ischaemic attacks and a mild thrombotic stroke in a HIV-positive patient with anticardiolipin antibodies.

D. Keeling, S. Machin, H. Birley, 1990, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Evaluation of a semi-automated reticulocyte counting method using the Coulter STKS-2A blood cell counter.

S. Machin, K. Patterson, J. Hamilton, 1995, Clinical and laboratory haematology.

Continuing developments with the automated platelet count 1

C Briggs, S J Machin, P Harrison, 2007, International journal of laboratory hematology.

A prospective randomized study of prophylactic teicoplanin to prevent early Hickman catheter‐related sepsis in patients receiving intensive chemotherapy for haematological malignancies

A. Goldstone, S. Machin, S. H. Lim, 1993, European journal of haematology. Supplementum.

A Flow Cytometric Approach to Quantitative Estimation of Platelet Surface Immunoglobulin G

S. Machin, S. Machin, C. Christopoulos, 1993, Vox sanguinis.

ICSH recommendations for the standardization of nomenclature and grading of peripheral blood cell morphological features

C Briggs, J. Burthem, S. Machin, 2015, International journal of laboratory hematology.

Effects of the lupus anticoagulant in patients with systemic lupus erythematosus on endothelial cell prostacyclin release and procoagulant activity.

D. Isenberg, M. Snaith, S. Machin, 1988, The Journal of investigative dermatology.

Managing anticoagulated patients during neuraxial anaesthesia

L. Green, S. Machin, 2010, British journal of haematology.

Clinical guidelines for testing for heritable thrombophilia

Elaine Gray, Ian Mackie, Beverley J Hunt, 2010, British journal of haematology.

Hydroxyethyl starch: an alternative to plasma for postoperative volume expansion after cardiac surgery.

T. Treasure, E. Macintyre, I. Mackie, 1989, The British journal of surgery.

A performance evaluation of chemiluminescence enzyme immunoassays on the Sysmex CN‐6500 haemostasis analyser

I. Mackie, S. Machin, C. Gardiner, 2021, International journal of laboratory hematology.

The in-vitro and ex-vivo effects of chloroquine sulphate on platelet function: implications for malaria prophylaxis in patients with impaired haemostasis.

S. Dawling, I. Mackie, S. Machin, 1990, The Journal of tropical medicine and hygiene.

Acquired Coagulation Disorders and Vascular Bleeding

H. Cohen, R. Liesner, S. Machin, 2007 .

Frequency and prevention of symptomless deep-vein thrombosis in long-haul flights: a randomised trial

I. Mackie, S. Machin, J. Scurr, 2001, The Lancet.

Effect of an evacuated blood collection system on coagulation screening tests.

I. Mackie, S. Machin, C. Jenkins, 1984, Journal of clinical pathology.

Fluid replacement in hypovolaemia

E. Macintyre, S. Machin, C. Bullen, 2004, Intensive Care Medicine.

Acute sensorineural deafness in Lassa fever.

J. McCormick, S. Fisher-Hoch, S. Machin, 1990, JAMA.

Comparison of the Automated Reticulocyte Counts and Immature Reticulocyte Fraction Measurements Obtained With the ABX Pentra 120 Retic Blood Analyzer and the Sysmex XE-2100 Automated Hematology Analyzer

S. Machin, C. Briggs, D. Grant, 2001 .

Accuracy of platelet counting haematology analysers in severe thrombocytopenia and potential impact on platelet transfusion

Paul J. Harrison, A. Casbard, M. Murphy, 2005, British journal of haematology.

A plasma inhibitor of platelet aggregation in patients with Argentine hemorrhagic fever.

J. Maiztegui, S. Machin, D. Cummins, 1989, The American journal of tropical medicine and hygiene.

Platelet counting by the RBC/platelet ratio method. A reference method.

Paul J. Harrison, N. Tatsumi, F. Lacombe, 2001, American journal of clinical pathology.

A phenotype–genotype correlation of ADAMTS13 mutations in congenital thrombotic thrombocytopenic purpura patients treated in the United Kingdom

R. Liesner, M. Scully, I. Mackie, 2012, Journal of thrombosis and haemostasis : JTH.

Exchange transfusion of a patient with fulminant Lassa fever.

S. Machin, D. Cummins, D. Bennett, 1991, Postgraduate medical journal.

Trigger factors for prophylactic platelet transfusion.

S. Machin, P. Ancliff, 1998, Blood reviews.

An interlaboratory study of a candidate reference method for platelet counting.

F. Lacombe, L. Van Hove, B. Houwen, 2001, American journal of clinical pathology.

Improved flagging rates on the Sysmex XE-5000 compared with the XE-2100 reduce the number of manual film reviews and increase laboratory productivity.

S. Machin, C. Briggs, J. Linssen, 2011, American journal of clinical pathology.

Performance Evaluation of the Sysmex XE-2100™, Automated Haematology Analyser

J. Staves, S. Machin, C. Briggs, 1999 .

Platelet Transfusion

I. Mackie, S. Machin, R. Warwick, 1995, Thrombosis and Haemostasis.

The value of the white precursor cell channel (WPC) on the Sysmex XN-1000 analyser in a specialist paediatric hospital

R. Liesner, S. Machin, C. Briggs, 2014, Journal of Clinical Pathology.

The clinical utility of ADAMTS13 activity, antigen and autoantibody assays in thrombotic thrombocytopenic purpura

M. Scully, I. Mackie, S. Machin, 2007, British journal of haematology.

The most accurate platelet count on the Sysmex XE-2100. Optical or impedance?

S. Machin, C. Briggs, S. Kunka, 2004, Clinical and laboratory haematology.

Defective platelet aggregation to the calcium ionophore A23187 in a patient with a lifelong bleeding disorder.

B. Mcverry, S. Machin, J. Keenan, 1983, Journal of clinical pathology.

Ontogeny of Beta 2 Glycoprotein I and Annexin V in Villous Placenta of Normal and Antiphospholipid Syndrome Pregnancies

J. Kingdom, E. Jauniaux, S. Quenby, 2000, Thrombosis and Haemostasis.

The role of complement activation in COPD exacerbation recovery

J. Wedzicha, G. Donaldson, M. Scully, 2016, ERJ Open Research.

The international consensus group for hematology review: suggested criteria for action following automated CBC and WBC differential analysis.

P W Barnes, S. Machin, S L McFadden, 2005, Laboratory hematology : official publication of the International Society for Laboratory Hematology.

The clinical significance of differences between point-of-care and laboratory INR methods in over-anticoagulated patients.

L. Green, H. Cohen, S. Machin, 2012, Thrombosis research.

Berend Houwen Memorial Lecture: ISLH Las Vegas May 2009

M. Scully, S. Machin, 2009, International journal of laboratory hematology.

Lack of pathogenic mutations in the 5′‐untranslated region of the thrombopoietin gene in patients with non‐familial essential thrombocythaemia

C. Harrison, D. Linch, S. Machin, 2001, European journal of haematology.

ABC of transfusion. Massive blood transfusion.

S. Machin, P. Hewitt, 1990, BMJ.

Can automated blood film analysis replace the manual differential? An evaluation of the CellaVision DM96 automated image analysis system

C Briggs, I Longair, M Slavik, 2009, International journal of laboratory hematology.

The use of the H*1 in predicting marrow recovery following ablative chemotherapy in leukaemia and lymphoma.

S. Machin, A. Goldstone, S. Kinsey, 1988, Clinical and laboratory haematology.

Rivaroxaban limits complement activation compared with warfarin in antiphospholipid syndrome patients with venous thromboembolism

D. Isenberg, M. Khamashta, H. Cohen, 2016, Journal of thrombosis and haemostasis : JTH.

Clinical and Immunological Characterisation of Coversin, a Novel Small Protein Inhibitor of Complement C5 with Potential As a Therapeutic Agent in PNH and Other Complement Mediated Disorders

Ian Mackie, Samuel J. Machin, Stephen J. Richards, 2014 .

ENDOTOXAEMIA IN NEUTROPENIC PATIENTS

S. Machin, S. Kinsey, 1988, The Lancet.

Anticoagulant, Antiplatelet, and Thrombolytic Drugs

L. Green, S. Machin, 2012 .

In vivo biotinylation studies: specificity of labelling of reticulated platelets by thiazole orange and mepacrine

Pille Harrison, I. Mackie, S. Machin, 2000, British journal of haematology.

ICSH recommendations for modified and alternate methods measuring the erythrocyte sedimentation rate

A. Kratz, M. Plebani, S. Machin, 2017, International journal of laboratory hematology.

Protein S levels are lower in women receiving desogestrel‐containing combined oral contraceptives (COCs) than in women receiving levonorgestrel‐containing COCs at steady state and on cross‐over

S. Furs, I. Mackie, S. Machin, 2001, British journal of haematology.

CHAPTER 24 – Platelet Counting

S. Machin, C. Briggs, P. Harrison, 2007 .

Advances in Platelet Counting

Pille Harrison, S. Machin, C. Briggs, 2001, Hematology.

Digital morphology analyzers in hematology: ICSH review and recommendations

Gina Zini, Alexander Kratz, Mina Hur, 2019, International journal of laboratory hematology.

Increased platelet count and leucocyte–platelet complex formation in acute symptomatic compared with asymptomatic severe carotid stenosis

Paul J. Harrison, Pille Harrison, P. Sidhu, 2005, Journal of Neurology, Neurosurgery & Psychiatry.

Relationship between ADAMTS13 activity, von Willebrand factor antigen levels and platelet function in the early and late phases after TIA or ischaemic stroke

P. Sidhu, M. Brown, M. Scully, 2015, Journal of the Neurological Sciences.

A performance evaluation of a novel human recombinant tissue factor prothrombin time reagent (Revohem™ PT)

S. Machin, I. Mackie, C. Gardiner, 2017, International journal of laboratory hematology.

A performance evaluation of a novel human recombinant tissue factor prothrombin time reagent (RevohemTM PT)

Mackie, S. Machin, J. Ian, 2017 .

Evaluation of a Low Molecular Weight Modulator of Human Plasminogen Activator Inhibitor-1 Activity

P. Charlton, S. Machin, J. Bryans, 1996, Thrombosis and Haemostasis.

Performance evaluation of a new compact hematology analyzer, the Sysmex pocH-100i.

S. Machin, C. Briggs, S. Kunka, 2003, Laboratory hematology : official publication of the International Society for Laboratory Hematology.

Tuberculosis and Severe Thrombocytopaenia

S. Machin, Y. C. Chia, 1979, The British journal of clinical practice.

Successful management of pregnancy in women with a history of TTP.

Marie Scully, Hannah Cohen, Richard D. Starke, 2006 .

A plasma factor inhibiting prostacyclin-like activity in thrombotic thrombocytopenic purpura.

B. Mcverry, S. Machin, H. Parry, 1982, Acta haematologica.

Factor VIII and ristocetin induced platelet aggregation after splenectomy.

S. Machin, M. Brozovīc, I. Mackie, 1978, Thrombosis research.

Regional UK TTP Registry: correlation with laboratory ADAMTS 13 analysis and clinical features

Ian Mackie, Beverley Hunt, J. Cavenagh, 2008, British journal of haematology.

Clinical annotation. Thrombotic thrombocytopenic purpura.

S. Machin, 1984, British journal of haematology.

SEROCONVERSION FOR HTLV-III SINCE 1980 IN BRITISH HAEMOPHILIACS

R. Tedder, S. Machin, R. Cheingsong-Popov, 1985, The Lancet.

Recommendations for patients undertaking self management of oral anticoagulation

D. Fitzmaurice, S. Machin, D. Fitzmaurice, 2001, BMJ : British Medical Journal.

Lupus Anticoagulant Measurement

S. Donohoe, I. Mackie, S. Machin, 2000 .

Protein C and Related Proteins

S. Machin, 1989 .

Dense granules non-specifically label with nucleic acid dyes used for reticulated platelet assays.

Paul J. Harrison, S. Machin, G. Savidge, 1997 .

Successful pregnancy outcome in 5 patients with thrombotic thrombocytopenic purpura.

Richard S. Lee, H. Cohen, M. Scully, 2005 .

Acute promyelocytic leukaemia

A. Goldstone, S. Machin, A. Fielding, 1994, The Lancet.

Platelet activation and turnover in the primary antiphospholipid syndrome

S. Donohoe, S. Machin, I. Mackie, 1998, Lupus.

Elevated levels of beta 2 glycoprotein-I (beta 2 GPI) in antiphospholipid antibody syndrome are due to increased amounts of beta 2 GPI in association with other plasma constituents.

D. Isenberg, I. Mackie, S. Machin, 1995, Blood Coagulation and Fibrinolysis.

Localization of βGPI and annexin V in villous placenta during normal and IUGR/APS pregnancies

J. Kingdom, E. Jauniaux, S. Quenby, 1998 .

Patient self‐testing is a reliable and acceptable alternative to laboratory INR monitoring

Chris Gardiner, Hannah Cohen, H. Cohen, 2005, British journal of haematology.

What are the Potential Future Treatments in Antiphospholipid Syndrome

H. Cohen, Anisur Rahman, S. Machin, 2012 .

Platelet hyperaggregability in a patient with Klinefelter's syndrome and leg ulcers

P. Norris, S. Machin, W. Griffiths, 1987, The British journal of dermatology.

Feasibility of a mean platelet volume standard: an international council for standardization in hematology (ICSH) inter-laboratory study

S. Machin, P. Harrison, Marie Didembourg, 2022, Platelets.

Plasmapheresis in the haemolytic-uraemic syndrome in children.

S. Machin, A. Murphy, T. Beattie, 1981, British medical journal.

Serum gamma-glutamyl transferase activity in volunteer blood donors.

B. Mcverry, S. Machin, T. Cleghorn, 1977, Journal of clinical pathology.

The Role of the Contact System in the Pathophysiology of ARDS

S. Machin, S. Kinsey, 1989 .

Anti-beta2-glycoprotein I, anti-prothrombin and anticardiolipin antibodies in a longitudinal study of patients with systemic lupus erythematosus and the antiphospholipid syndrome.

D. Isenberg, M. Inanç, S. Donohoe, 1998, British journal of rheumatology.

Heparin‐induced thrombocytopenia following plasma exchange in patients with demyelinating neurological disease

H. Cohen, S. Machin, D. Arachchillage, 2015, International journal of laboratory hematology.

Platelet hyper-function in acute coronary syndromes

A. Mathur, I. Mackie, S. Machin, 2005, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

ICSH guidance for INR and D‐dimer testing using point of care testing in primary care

D. Fitzmaurice, X. Armoiry, S. Kitchen, 2023, International journal of laboratory hematology.

Platelet counting.

Paul J. Harrison, S. Machin, C. Briggs, 2004, Methods in molecular biology.

Lack of Specific Binding of Anticardiolipin Antibodies to Intact Platelets

G. Hughes, S. Machin, H. Haga, 1992, Lupus.

Lack of association of b 2-glycoprotein I polymorphisms Val247Leu and Trp316Ser with antiphospholipid antibodies in patients with thrombosis and pregnancy complications

S. Humphries, H. Cohen, I. Mackie, 2003 .

Complement and cytokine response in acute Thrombotic Thrombocytopenic Purpura

M. Scully, J. Westwood, S. Machin, 2014, British journal of haematology.

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) INCREASES PLASMA FIBRINOLYTIC-ACTIVITY IN-VIVO

D. Linch, I. Mackie, S. Machin, 1994 .

Successful treatment of congenital thrombotic thrombocytopenic purpura using the intermediate purity factor VIII concentrate BPL 8Y

S. Machin, S. Allford, W. Lester, 2002, British journal of haematology.

HIGHLY PURIFIED PORCINE FACTOR VIII IN HAEMOPHILIA A

I. Mackie, S. Machin, P. Hewitt, 1982, The Lancet.

Prothrombotic changes in children with sickle cell disease: relationships to cerebrovascular disease and transfusion

Hann, McDonald, Mackie, 1998, British journal of haematology.

ICSH guidelines for the evaluation of blood cell analysers including those used for differential leucocyte and reticulocyte counting

C Briggs, S. Machin, G. Zini, 2014, International journal of laboratory hematology.

Vascular endothelial cell function and ultrastructure in thrombotic microangiopathy following allogeneic bone marrow transplantation

F. Hill, N. Woolf, S. Machin, 1989, European journal of haematology.

D. Isenberg, C. Doré, M. Khamashta, 2016, The Lancet. Haematology.

Heparin clearance during continuous veno-venous haemofiltration

G. Screaton, I. Mackie, S. Machin, 2005, Intensive Care Medicine.

Diagnosis of antiphospholipid syndrome in routine clinical practice

H. Cohen, S. Machin, J. Hills, 2013, Lupus.

Human monoclonal anti‐phospholipid antibodies selectively bind to membrane phospholipid and β2‐glycoprotein I (β2‐GPI) on apoptotic cells

D. Isenberg, P. Lydyard, S. Donohoe, 2000, Clinical and experimental immunology.

The accuracy of platelet counting in thrombocytopenic blood samples distributed by the UK National External Quality Assessment Scheme for General Haematology.

Paul Harrison, P. McTaggart, K. Hyde, 2012, American journal of clinical pathology.

ADAMTS‐13 assays in thrombotic thrombocytopenic purpura

F. Peyvandi, R. Palla, M. Scully, 2010, Journal of thrombosis and haemostasis : JTH.

Pros and cons of thrombophilia testing: cons

S. Machin, S. Machin, 2003, Journal of thrombosis and haemostasis : JTH.

Rituximab pharmacokinetics during the management of acute idiopathic thrombotic thrombocytopenic purpura

M. Scully, I. Mackie, S. Machin, 2010, Journal of thrombosis and haemostasis : JTH.

Guidelines for the use of fresh frozen plasma

F. Ala, S. Machin, M. Greaves, 1992 .

Two colour analysis of reticulated platelets.

I. Mackie, S. Machin, I. Mackie, 2000, Clinical and laboratory haematology.

Prevalence of the ADAMTS‐13 missense mutation R1060W in late onset adult thrombotic thrombocytopenic purpura

H. Cohen, D. Lane, M. Scully, 2008, Journal of thrombosis and haemostasis : JTH.

Cardiac involvement in acute thrombotic thrombocytopenic purpura: association with troponin T and IgG antibodies to ADAMTS 13

J. McEwan, H. Cohen, M. Scully, 2009, Journal of thrombosis and haemostasis : JTH.

Rituximab for thrombotic thrombocytopenic purpura: benefit of early administration during acute episodes and use of prophylaxis to prevent relapse

M. Scully, J. Westwood, S. Machin, 2013, Journal of thrombosis and haemostasis : JTH.

INHERITED AND ACQUIRED COAGULATION DISORDERS

S. Machin, V. Mcdonald, 2013, Color Atlas of Clinical Hematology.

DEVELOPMENT OF A CONSENSUS STANDARD REFERENCE METHOD FOR IMMATURE PLATELETS: O47

S. Machin, 2013 .

Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link

M. Scully, S. Machin, S. Machin, 2010, Journal of thrombosis and haemostasis : JTH.

Congenital combined factor VII and factor VIII deficiency.

B. R. Miller, S. Machin, 1980, Acta haematologica.

Rituximab pharmacokinetics during the management of acute idiopathic thrombotic thrombocytopenic purpura

M. Scully, I. Mackie, S. Machin, 2010, Journal of thrombosis and haemostasis : JTH.

Platelet Counting

Paul J. Harrison, S. Machin, C. Briggs, 2019, Platelets.

Paradoxical association between the 316 Trp to Ser beta 2‐glycoprotein I (Beta2GPI) polymorphism and anti‐Beta2GPI antibodies

H. Cohen, R. Liesner, I. Mackie, 2003, British journal of haematology.

Thrombin generation and factor X assays for the assessment of warfarin anticoagulation in thrombotic antiphospholipid syndrome.

H. Cohen, I. Mackie, S. Machin, 2015, Thrombosis research.

Relationship between ADAMTS13 activity, von Willebrand factor antigen levels and platelet function in the early and late phases after TIA or ischaemic stroke

Pille Harrison, P. Sidhu, M. Scully, 2015, Journal of the Neurological Sciences.

A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura.

J. Cavenagh, H. Cohen, B. Hunt, 2011, Blood.

Discrepancies between ADAMTS13 activity assays in patients with thrombotic microangiopathies

F. Peyvandi, R. Liesner, M. Scully, 2013, Thrombosis and Haemostasis.

Cardiac involvement in acute thrombotic thrombocytopenic purpura: association with troponin T and IgG antibodies to ADAMTS 13

J. McEwan, H. Cohen, M. Scully, 2009, Journal of thrombosis and haemostasis : JTH.

Autoimmune thrombocytopenia in primary antiphospholipid syndrome and systemic lupus erythematosus: the response to splenectomy.

D. Isenberg, S. Machin, S. Machin, 1998, Seminars in arthritis and rheumatism.

Antiphospholipid antibodies and essential thrombocythemia.

C. Harrison, S. Machin, 1997, The American journal of medicine.

Platelet activation markers and the primary antiphospholipid syndrome (PAPS)

Pille Harrison, I. Mackie, S. Machin, 1998, Lupus.

Monitoring of oral anticoagulant therapy in lupus anticoagulant positive patients with the anti‐phospholipid syndrome

I. Mackie, S. Machin, I. Mackie, 1997, British journal of haematology.