B. L. Langille

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Regulation of vascular connexin43 gene expression by mechanical loads.

Douglas B. Cowan, S. Lye, B. L. Langille, 1998, Circulation research.

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

Tak W. Mak, José Luis de la Pompa, Hiroaki Takimoto, 1998, Nature.

Cardiac malformation in neonatal mice lacking connexin43.

B L Langille, J. Rossant, A. Reaume, 1995, Science.

Effects of anastomotic angle on vascular tissue responses at end-to-side arterial grafts.

B L Langille, A. Gotlieb, B. L. Langille, 2001, Journal of vascular surgery.

Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent.

B L Langille, B. L. Langille, F. O'Donnell, 1986, Science.

Arterial adaptations to chronic changes in haemodynamic function: coupling vasomotor tone to structural remodelling.

B. L. Langille, D. Dajnowiec, B Lowell Langille, 2007, Clinical science.

The effect of local blood flow patterns on endothelial cell morphology.

M. Reidy, B. L. Langille, B. Langille, 1980, Experimental and molecular pathology.

Injury and Repair of Endothelium at Sites of Flow Disturbances Near Abdominal Aortic Coarctations in Rabbits

R L Kline, B L Langille, M. Reidy, 1986, Arteriosclerosis.

Relationship between Blood Flow Direction and Endothelial Cell Orientation at Arterial Branch Sites in Rabbits and Mice

B L Langille, B. L. Langille, S L Adamson, 1981, Circulation research.

Adaptations of carotid arteries of young and mature rabbits to reduced carotid blood flow.

B L Langille, F. Keeley, B. L. Langille, 1989, The American journal of physiology.

Apoptosis During Cardiovascular Development

D. Srivastava, B. L. Langille, S. Fisher, 2000, Circulation research.

Apoptosis and Heart Failure: A Critical Review of the Literature Vascular Cell Apoptosis in Remodeling, Restenosis, and Plaque Rupture Endothelial Cell Apoptosis in Angiogenesis and Vessel Regression Apoptosis During Cardiovascular Development Myocyte Apoptosis in Ischemic Heart Disease

D. Srivastava, B. L. Langille, S. Fisher, 2000 .

Cardiovascular responses attenuate with repeated NO synthesis inhibition in conscious fetal sheep.

B. L. Langille, S. Adamson, A. Chlorakos, 1998, American journal of physiology. Heart and circulatory physiology.

Three patterns of distribution characterize the organization of endothelial microfilaments at aortic flow dividers

A. Gotlieb, B. L. Langille, S. Colangelo, 1994, Cell and Tissue Research.

CHAPTER 8 – Chronic Effects of Blood Flow on the Artery Wall

B. L. Langille, B. Langille, 1993 .

Mechanotransduction by endothelial cells is locally generated, direction‐dependent, and ligand‐specific

B. L. Langille, A. Kapus, Ming Zhang, 2010, Journal of cellular physiology.

Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression.

A. Nagy, B. L. Langille, L. Miquerol, 2000, Development.

Endothelium-Independent Flow-Induced Dilation in the Mouse Carotid Artery

B. L. Langille, S. Adamson, A. Quan, 2006, Journal of Vascular Research.

Patterns of Endothelial Microfilament Distribution in the Rabbit Aorta In Situ

A. Gotlieb, B. L. Langille, M. Wong, 1989, Circulation research.

Mitogen-activated protein kinases mediate stretch-induced c-fos mRNA expression in myometrial smooth muscle cells.

Mingyao Liu, S. Lye, O. Shynlova, 2002, American journal of physiology. Cell physiology.

Blood flow-induced remodeling of arteries in health and disease.

B. L. Langille, 1992, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Tied down by shear force: role for Tie1 in postnatal vascular remodeling?

D. Stewart, B. L. Langille, 2004, Circulation research.

In situ localization of F-actin microfilaments in the vasculature of the porcine retina.

A. Gotlieb, B. L. Langille, B. I. Strauss, 1987, Experimental eye research.

Atrophic remodeling of the artery-cuffed artery.

B. L. Langille, S. Adamson, Ilana M. Bayer, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Central cardiovascular dynamics of ducks.

D. Jones, B. L. Langille, B. Langille, 1975, The American journal of physiology.

Rapid accumulation of elastin and collagen in the aortas of sheep in the immediate perinatal period.

B. L. Langille, M. Bendeck, B. Langille, 1991, Circulation research.

Cross-Linking Vasomotor Tone and Vascular Remodeling: A Novel Function for Tissue Transglutaminase?

B. L. Langille, D. Dajnowiec, B. Langille, 2004, Circulation research.

Maternal cardiovascular changes during pregnancy and postpartum in mice.

B. L. Langille, S. Adamson, D. Qu, 2002, American journal of physiology. Heart and circulatory physiology.

The expression of transforming growth factor beta in pregnant rat myometrium is hormone and stretch dependent.

S. Lye, O. Shynlova, B. L. Langille, 2007, Reproduction.

Insulin-like Growth Factors and Their Binding Proteins Define Specific Phases of Myometrial Differentiation During Pregnancy in the Rat1

S. Lye, O. Shynlova, B. L. Langille, 2007, Biology of reproduction.

Reflex control of arterial compliance in rabbits.

B. L. Langille, C. Osberg, 1982, Canadian journal of physiology and pharmacology.

Structure and function of the endothelial cytoskeleton.

B. L. Langille, M. Wong, A. Gottlieb, 1991, Laboratory investigation; a journal of technical methods and pathology.

Force-Induced Polarized Mitosis of Endothelial and Smooth Muscle Cells in Arterial Remodeling

B. L. Langille, D. Dajnowiec, A. Kapus, 2007, Hypertension.

Alterations in endothelial F-actin microfilaments in rabbit aorta in hypercholesterolemia.

A. Gotlieb, B. L. Langille, G. Steiner, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Cardiovascular responses attenuate with repeated NO synthesis inhibition in conscious fetal sheep.

B. L. Langille, S. Adamson, A. Chlorakos, 1998, The American journal of physiology.

Perinatal accumulation of arterial wall constituents: relation to hemodynamic changes at birth.

F. Keeley, B. L. Langille, M. Bendeck, 1994, The American journal of physiology.

Progesterone and Gravidity Differentially Regulate Expression of Extracellular Matrix Components in the Pregnant Rat Myometrium1

Jennifer A. Mitchell, S. Lye, O. Shynlova, 2004, Biology of reproduction.

Partial Off-Loading of Longitudinal Tension Induces Arterial Tortuosity

A. Gotlieb, B. L. Langille, D. Dajnowiec, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Role of venoconstriction in the cardiovascular responses of ducks to head immersion.

B. L. Langille, B. Langille, 1983, The American journal of physiology.

Vagal control of pulmonary vascular resistance in the turtle Chrysemys scripta.

D. Jones, W. Milsom, B. L. Langille, 1977, Canadian journal of zoology.

Dynamics of shear-induced redistribution of F-actin in endothelial cells in vivo.

B L Langille, A. Gotlieb, B. L. Langille, 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

Arterial remodeling: relation to hemodynamics.

B L Langille, B. L. Langille, B. Langille, 1996, Canadian journal of physiology and pharmacology.

Morphologic Responses of Endothelium to Shear Stress: Reorganization of the Adherens Junction

B. L. Langille, B. Langille, 2001, Microcirculation.

Pulsatile pressure-flow relations and pulse-wave propagation in the umbilical circulation of fetal sheep.

B. L. Langille, S. Adamson, K. Whiteley, 1992, Circulation research.

Vasomotor responses of the umbilical circulation in fetal sheep.

S. Bull, B. L. Langille, S. Adamson, 1989, The American journal of physiology.

Factors determining aortic and umbilical blood flow pulsatility in fetal sheep.

B. L. Langille, S. Adamson, B. Langille, 1992, Ultrasound in medicine & biology.

Site-dependent effects of increases in placental vascular resistance on the umbilical arterial velocity waveform in fetal sheep.

S. Bull, B. L. Langille, S. Adamson, 1990, Ultrasound in medicine & biology.

N-Cadherin Upregulation and Function in Response of Smooth Muscle Cells to Arterial Injury

B. L. Langille, M. Bendeck, F. Lee, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Blood flow in dorsal and ventral aortas of the cod, Gadus morhua.

D. Jones, D. Randall, B. L. Langille, 1974, The American journal of physiology.

Cardiovascular and respiratory flow dynamics

B. L. Langille, A. Anantaraman, E. Stevens, 1983 .

Dynamics of blood flow through the hearts and arterial systems of anuran amphibia.

D. Jones, B. L. Langille, B. Langille, 1977, The Journal of experimental biology.

Cellular and molecular biology of vascular remodeling

B L Langille, Douglas B. Cowan, B. L. Langille, 1996, Current opinion in lipidology.

Evidence that turbulence is not the cause of poststenotic dilatation in rabbit carotid arteries.

M. Ojha, B. L. Langille, B. Langille, 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

ovine thoracic aorta Determinants of mechanical properties in the developing

S. Wells, B. L. Langille, J. M. Lee, 2013 .

Determinants of mechanical properties in the developing ovine thoracic aorta.

S. Wells, B. L. Langille, J. M. Lee, 1999, American journal of physiology. Heart and circulatory physiology.

Determinants of mechanical properties in the developing ovine thoracic aorta.

B L Langille, S. Wells, B. L. Langille, 1999, The American journal of physiology.

Thermomechanical analysis of collagen crosslinking in the developing ovine thoracic aorta.

B L Langille, S. Wells, B. L. Langille, 1998, Biorheology.

In vivo and in vitro mechanical properties of the sheep thoracic aorta in the perinatal period and adulthood.

B L Langille, S. Wells, B. L. Langille, 1998, The American journal of physiology.

In vivo and in vitro mechanical properties of the sheep thoracic aorta in the perinatal period and adulthood.

S. Wells, B. L. Langille, S. Adamson, 1998, American journal of physiology. Heart and circulatory physiology.

Modulation of Arterial Growth of the Rabbit Carotid Artery Associated with Experimental Elevation of Blood Flow

B. L. Langille, Ida Di Stefano, D. Koopmans, 1998, Journal of Vascular Research.

Blood Flow-Induced Remodeling of the Artery Wall

B. L. Langille, B. Lowell Langille, B. Langille, 1995 .

Adaptations of Mature and Developing Arteries to Local Hemodynamics

B. L. Langille, B. Langille, 1991 .

In vivo modulation of endothelial F-actin microfilaments by experimental alterations in shear stress.

A. Gotlieb, B. L. Langille, D. Kim, 1989, Arteriosclerosis.

Apoptosis (programmed cell death) in arteries of the neonatal lamb.

B L Langille, A. Cho, D. Courtman, 1995, Circulation research.

Blood flow, Shear Stress and Remodeling of the Artery Wall

B. L. Langille, B. Langille, 1997 .

Wall Tissue Remodeling Regulates Longitudinal Tension in Arteries

Avrum I. Gotlieb, A. Gotlieb, B. L. Langille, 2002, Circulation research.

Arterial adaptations to altered blood flow.

B L Langille, B. L. Langille, R D Brownlee, 1991, Canadian journal of physiology and pharmacology.

A wave transmission model of the umbilicoplacental circulation based on hemodynamic measurements in sheep.

R. Cobbold, L. Mo, B. L. Langille, 1995, The American journal of physiology.

Transient and steady-state effects of shear stress on endothelial cell adherens junctions.

B L Langille, Douglas B. Cowan, A. Gotlieb, 1999, Circulation research.

Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress.

B L Langille, M. Cybulsky, A. Gotlieb, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Assembly and reorientation of stress fibers drives morphological changes to endothelial cells exposed to shear stress.

Feng Xu, A. Gotlieb, B. L. Langille, 2004, The American journal of pathology.

Developmental remodeling of the internal elastic lamina of rabbit arteries: effect of blood flow.

B L Langille, B. L. Langille, L C Wong, 1996, Circulation research.

Myometrial programming: a new concept underlying the regulation of myometrial function during pregnancy

Jennifer A. Mitchell, S. Lye, O. Shynlova, 2007 .

Homotypic and Endothelial Cell Adhesions via N-Cadherin Determine Polarity and Regulate Migration of Vascular Smooth Muscle Cells

R. Silverman-Gavrila, B. L. Langille, Ming Zhang, 2008, Circulation research.

Monocyte adhesion and changes in endothelial cell number, morphology, and F-actin distribution elicited by low shear stress in vivo.

B L Langille, A. Gotlieb, B. L. Langille, 1993, The American journal of pathology.

Shear Stress Regulates Forward and Reverse Planar Cell Polarity of Vascular Endothelium In Vivo and In Vitro

B. L. Langille, D. Dajnowiec, Ming Zhang, 2006, Circulation research.

Perinatal aortic growth in lambs: relation to blood flow changes at birth.

B L Langille, B. L. Langille, S L Adamson, 1990, The American journal of physiology.

Structural changes and recovery of function after arterial injury.

B. L. Langille, M. Bendeck, A. Jamal, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Endothelin-1 constricts fetoplacental microcirculation and decreases fetal O2 consumption in sheep.

B. L. Langille, S. Adamson, K. Whiteley, 1996, The American journal of physiology.

Blood flow dynamics, atherosclerosis and bypass graft failure.

M. Ojha, B. L. Langille, B. Langille, 1997, Trends in cardiovascular medicine.

Decreased blood flow rate disrupts endothelial repair in vivo.

B L Langille, A. Gotlieb, B. L. Langille, 1996, The American journal of pathology.

Changes in blood flow distribution during the perinatal period in fetal sheep and lambs.

B. L. Langille, M. Bendeck, B. Langille, 1992, Canadian journal of physiology and pharmacology.

Shear-induced reorganization of endothelial cell cytoskeleton and adhesion complexes.

B. L. Langille, S. Noria, Shannon McCue, 2004, Trends in cardiovascular medicine.

Pressure wave propagation and input impedance in thoracic aorta of conscious newborn sheep.

B. L. Langille, S. Adamson, K. Whiteley, 1995, The American journal of physiology.

Branching characteristics of coronary arteries in rats.

B L Langille, M Zamir, T. Wonnacott, 1984, Canadian journal of physiology and pharmacology.

Arterial bifurcations in the cardiovascular system of a rat

B L Langille, M Zamir, M. Zamir, 1983, The Journal of general physiology.

Integrin-linked kinase in the vascular smooth muscle cell response to injury.

J. Pickering, G. Hannigan, B. L. Langille, 2008, The American journal of pathology.

Examination of elastic non-uniformity in the arterial system using a hydraulic model.

B L Langille, D R Jones, D. Jones, 1976, Journal of biomechanics.

Effects of changes in blood flow rate on cell death and cell proliferation in carotid arteries of immature rabbits.

A. Cho, B. L. Langille, D. Koopmans, 1997, Circulation research.

Mechanical interaction between the ventricles during systole.

D. Jones, B. L. Langille, B. Langille, 1977, Canadian journal of physiology and pharmacology.

Mechanical stretch and progesterone differentially regulate activator protein-1 transcription factors in primary rat myometrial smooth muscle cells.

Jennifer A. Mitchell, S. Lye, O. Shynlova, 2004, American journal of physiology. Endocrinology and metabolism.