N. Avadhani

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Defects in cytochrome c oxidase expression induce a metabolic shift to glycolysis and carcinogenesis

D. Dong, S. Srinivasan, M. Guha, 2015, Genomics data.

Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q.

D. Aggarwal, R. Migrino, J. Joseph, 2009, Biophysical journal.

Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals

P. Bajpai, S. Bansal, N. Avadhani, 2011, The FEBS journal.

Physiological Role of the N-terminal Processed P4501A1 Targeted to Mitochondria in Erythromycin Metabolism and Reversal of Erythromycin-mediated Inhibition of Mitochondrial Protein Synthesis*

N. Avadhani, C. Vijayasarathy, G. Biswas, 1999, The Journal of Biological Chemistry.

Hypoxia‐Mediated Mitochondrial Stress in RAW264.7 Cells Induces Osteoclast‐Like TRAP‐Positive Cells

S. Srinivasan, N. Avadhani, 2007, Annals of the New York Academy of Sciences.

Preferential attack of mitochondrial DNA by aflatoxin B1 during hepatocarcinogenesis.

N. Avadhani, B. G. Niranjan, N. K. Bhat, 1982, Science.

beta1-Adrenoreceptor activation contributes to ischemia-reperfusion damage as well as playing a role in ischemic preconditioning.

J. Spear, D. Galati, N. Avadhani, 2007, American journal of physiology. Heart and circulatory physiology.

Protein Kinase A-mediated Phosphorylation Modulates Cytochrome c Oxidase Function and Augments Hypoxia and Myocardial Ischemia-related Injury*

S. Srinivasan, N. Avadhani, H. Raza, 2006, Journal of Biological Chemistry.

Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo- and heterodimers.

B. Kalyanaraman, S. Srinivasan, N. Avadhani, 2008, Free radical biology & medicine.

ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds.

A. Klein-Szanto, H. Nakagawa, E. Noguchi, 2016, American journal of cancer research.

Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia.

C. Otto, N. Avadhani, C. Vijayasarathy, 2003, European journal of biochemistry.

Role of mitochondrial reactive oxygen species in osteoclast differentiation

Li Sun, M. Zaidi, J. Joseph, 2010, Annals of the New York Academy of Sciences.

Accumulation of Mitochondrial P450MT2, NH2-terminal Truncated Cytochrome P4501A1 in Rat Brain during Chronic Treatment with β-Naphthoflavone

N. Avadhani, E. Boopathi, G. Biswas, 2000, The Journal of Biological Chemistry.

Oxidative Stress Induced Mitochondrial Protein Kinase A Mediates Cytochrome C Oxidase Dysfunction

J. Joseph, B. Kalyanaraman, S. Srinivasan, 2013, PloS one.

Mitochondria-to-nucleus stress signaling in mammalian cells: nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis.

M. Guha, N. Avadhani, G. Biswas, 2005, Gene.

Identification of genetic variants of human cytochrome P450 2D6 with impaired mitochondrial targeting.

F. Guengerich, N. Avadhani, M. C. Sangar, 2010, Molecular genetics and metabolism.

Human liver mitochondrial cytochrome P450 2D6 – individual variations and implications in drug metabolism

F. Guengerich, N. Avadhani, Weigang Tang, 2009, The FEBS journal.

Mitochondrial Stress Induced p53 Attenuates HIF-1α Activity by Physical Association and Enhanced Ubiquitination

A. Rustgi, S. Fuchs, A. Chowdhury, 2016, Oncogene.

Phosphorylation Enhances Mitochondrial Targeting of GSTA4-4 through Increased Affinity for Binding to Cytoplasmic Hsp70*

M. Robin, N. Avadhani, H. Raza, 2003, Journal of Biological Chemistry.

Cigarette Smoke Toxins-Induced Mitochondrial Dysfunction and Pancreatitis Involves Aryl Hydrocarbon Receptor Mediated Cyp1 Gene Expression: Protective Effects of Resveratrol

A. Rustgi, S. Fuchs, F. Gonzalez, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Enhanced osteoclastogenesis by mitochondrial retrograde signaling through transcriptional activation of the cathepsin K gene

M. Zaidi, S. Srinivasan, M. Guha, 2016, Annals of the New York Academy of Sciences.

Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Calpha in C2C12 myocytes.

Ying Wang, N. Avadhani, G. Biswas, 2006, Biochemical pharmacology.

Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP‐dependent phosphorylation at Ser128

L. Otvos, L. Otvos, D. Pain, 1999, The EMBO journal.

Targeting of NH2-terminal–processed Microsomal Protein to Mitochondria: A Novel Pathway for the Biogenesis of Hepatic Mitochondrial P450MT2

S. Addya, N. Avadhani, G. Biswas, 1997, The Journal of cell biology.

Targeting of NH 2-terminal – processed Microsomal Protein to Mitochondria : A Novel Pathway for the Biogenesis of Hepatic Mitochondrial P 450 MT 2

S. Addya, N. Avadhani, G. Biswas, 1997 .

Down-regulation of the rat hepatic sterol 27-hydroxylase gene by bile acids in transfected primary hepatocytes: possible role of hepatic nuclear factor 1α

R. Stravitz, P. Hylemon, Y. Rao, 1999, The Journal of Steroid Biochemistry and Molecular Biology.

Formation of benzo(alpha)pyrene metabolites and DNA adducts catalyzed by a rat liver mitochondrial monooxygenase system.

J. DiGiovanni, N. Avadhani, B. G. Niranjan, 1985, Biochemical and biophysical research communications.

Role of Polycyclic Aromatic Hydrocarbons and Aryl Hydrocarbon Receptor Activation in Bone Loss

N. Avadhani, H. R. Kazmi, 2020 .

Multiple isoforms of mitochondrial glutathione S-transferases and their differential induction under oxidative stress.

M. Robin, N. Avadhani, H. Raza, 2002, The Biochemical journal.

Mitochondria-targeted Cytochrome P450 2E1 Induces Oxidative Damage and Augments Alcohol-mediated Oxidative Stress*

J. Hoek, F. P. Guengerich, G. Milne, 2010, The Journal of Biological Chemistry.

Mitochondrial Targeting of Cytochrome P450 (CYP) 1B1 and Its Role in Polycyclic Aromatic Hydrocarbon-induced Mitochondrial Dysfunction*

F. Guengerich, F. Gonzalez, S. Bansal, 2014, The Journal of Biological Chemistry.

Human Cytochrome P450 2E1 Mutations That Alter Mitochondrial Targeting Efficiency and Susceptibility to Ethanol-induced Toxicity in Cellular Models*

F. P. Guengerich, G. Milne, S. Bansal, 2013, The Journal of Biological Chemistry.

Protection of mitochondrial genetic system against aflatoxin B1 binding in animals resistant to aflatoxicosis.

N. Avadhani, H. Schaefer, B. G. Niranjan, 1986, Cancer research.

Preferential effects of nicotine and 4-(N-methyl-N-nitrosamine)-1-(3-pyridyl)-1-butanone on mitochondrial glutathione S-transferase A4-4 induction and increased oxidative stress in the rat brain.

N. Avadhani, C. Vijayasarathy, H. Raza, 1998, Biochemical pharmacology.

A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries.

H. Rennert, J. Strauss, S. Addya, 1990, DNA and cell biology.

Alcohol-induced CYP2E1, Mitochondrial Dynamics and Retrograde Signaling in Human Hepatic 3D Organoids.

G. Ruthel, B. Kalyanaraman, A. Chowdhury, 2020, Free radical biology & medicine.

Role of Protein Kinase C-mediated Protein Phosphorylation in Mitochondrial Translocation of Mouse CYP1A1, Which Contains a Non-canonical Targeting Signal*

D. Nebert, V. R. Dasari, M. Robin, 2006, Journal of Biological Chemistry.

A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis

Li Sun, M. Zaidi, A. Koval, 1999, Nature Cell Biology.

Mitochondrial respiratory defects promote the Warburg effect and cancer progression

S. Srinivasan, M. Guha, N. Avadhani, 2016, Molecular & cellular oncology.

Polysome-dependent in vitro translation system capable of peptide chain reinitiation.

I. Biunno, N. Avadhani, R. Watt, 1980, Biochemistry.

Messenger ribonucleic acid metabolism in mammalian mitochondria. Isolation and characterization of polyribosomes from Ehrlich ascites mitochondria.

N. Avadhani, R. Rutman, F. S. Lewis, 1976, Biochemistry.

Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes

T. Yuen, C. Hunter, D. Nebert, 2013, Proceedings of the National Academy of Sciences.

YY1 control of mitochondrial‐related genes does not account for regulation of immunoglobulin class switch recombination in mice

S. Nandi, Sarmistha Banerjee, M. Atchison, 2020, European journal of immunology.

Overexpression of CYP27 in hepatic and extrahepatic cells: role in the regulation of cholesterol homeostasis.

P. Hylemon, W. Pandak, N. Avadhani, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Transcriptional regulation of hepatic sterol 27-hydroxylase by bile acids.

R. Stravitz, P. Hylemon, W. Pandak, 1996, The American journal of physiology.

Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes

R. Stravitz, P. Hylemon, N. Avadhani, 1996, The Journal of Steroid Biochemistry and Molecular Biology.

Localization of a transcription promoter within the second exon of the cytochrome P-450c27/25 gene for the expression of the major species of two-kilobase mRNA.

S. Addya, N. Avadhani, C. Sucharov, 1995, Biochemistry.

Elevated mitochondrial cytochrome P450 2E1 and glutathione S-transferase A4-4 in streptozotocin-induced diabetic rats: tissue-specific variations and roles in oxidative stress.

M. Robin, N. Avadhani, H. Raza, 2004, Diabetes.

Leucine-rich pentatricopeptide-repeat containing protein regulates mitochondrial transcription.

Marni J. Falk, M. Falk, N. Sondheimer, 2010, Biochemistry.

Interaction of adrenodoxin with P4501A1 and its truncated form P450MT2 through different domains: differential modulation of enzyme activities.

S. Addya, N. Avadhani, J. Mullick, 1998, Biochemistry.

Hepatic mitochondrial cytochrome P-450 system. Distinctive features of cytochrome P-450 involved in the activation of aflatoxin B1 and benzo(a)pyrene.

C. Jefcoate, N. Avadhani, N. Wilson, 1984, The Journal of biological chemistry.

A novel transcriptional initiator activity of the GABP factor binding ets sequence repeat from the murine cytochrome c oxidase Vb gene.

N. Avadhani, C. Sucharov, R. S. Carter, 1995, Gene expression.

Regulation of Murine Cytochrome c Oxidase Vb Gene Expression during Myogenesis

M. Atchison, N. Lenka, N. Avadhani, 2004, Journal of Biological Chemistry.

The Effects of Smoke Carcinogens on Bone

C. Yan, J. Iqbal, N. Avadhani, 2011, Current osteoporosis reports.

Studies on messenger RNA from Euglena gracilis. I. Techniques of saline fractionation and characterization of messenger RNAs from dividing cells.

D. E. Buetow, N. Avadhani, 1972, Biochimica et biophysica acta.

Messenger ribonucleic acid metabolism in mammalian mitochondria: relationship between the decay of mitochondrial mRNA and their poly(A).

N. Avadhani, 1979, Biochemistry.

Transport of proteins into hepatic and nonhepatic mitochondria: specificity of uptake and processing of precursor forms of carbamoyl-phosphate synthetase I.

N. Avadhani, N. K. Bhat, 1985, Biochemistry.

Impaired Mitochondrial Respiratory Functions and Oxidative Stress in Streptozotocin-Induced Diabetic Rats

N. Avadhani, H. Raza, S. K. Prabu, 2011, International journal of molecular sciences.

Cooperative binding of GA-binding protein transcription factors to duplicated transcription initiation region repeats of the cytochrome c oxidase subunit IV gene.

N. Avadhani, R. S. Carter, 1994, The Journal of biological chemistry.

Translation of a Purified DNA–RNA Complex

D. E. Buetow, N. Avadhani, 1970, Nature.

Mitochondrial dysfunction in myocardium obtained from clinically normal dogs, clinically normal anesthetized dogs, and dogs with dilated cardiomyopathy.

S. Bansal, N. Avadhani, M. Sleeper, 2012, American journal of veterinary research.

Constitutive and inducible forms of cytochrome P450 from hepatic mitochondria.

S. Addya, N. Avadhani, R. Shayiq, 1991, Methods in enzymology.

A phenobarbital-inducible hepatic mitochondrial cytochrome P-450 immunochemically related to microsomal P-450b.

N. Avadhani, R. Shayiq, 1990, Biochemistry.

Hepatic mitochondrial cytochrome P-450 system. Purification and characterization of two distinct forms of mitochondrial cytochrome P-450 from beta-naphthoflavone-induced rat liver.

N. Avadhani, H. Raza, 1988, The Journal of biological chemistry.

Tissue variant effects of heme inhibitors on the mouse cytochrome c oxidase gene expression and catalytic activity of the enzyme complex.

N. Lenka, N. Avadhani, C. Vijayasarathy, 1999, European journal of biochemistry.

Mode of transcription and maturation of ribosomal ribonucleic acid in vitro in mitochondria from Ehrlich ascites cells.

N. Avadhani, K. S. Bhat, G. Kantharaj, 1983, Biochemistry.

The basal promoter elements of murine cytochrome c oxidase subunit IV gene consist of tandemly duplicated ets motifs that bind to GABP-related transcription factors.

N. Avadhani, N. K. Bhat, R. S. Carter, 1992, The Journal of biological chemistry.

Protein synthesis on polysomes in mitochondria isolated from Euglena gracilis.

M. Lynch, D. E. Buetow, N. Avadhani, 1971, Experimental cell research.

A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca 2 (cid:1) signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD (cid:1) sensor

Li Sun, M. Zaidi, A. Koval, 2002 .

Sequence complementarity between the 5'-terminal regions of mRNAs for rat mitochondrial cytochrome P-450c27/25 and a growth hormone-inducible serine protease inhibitor. A possible gene overlap.

N. Avadhani, R. Shayiq, 1992, The Journal of biological chemistry.

Competitive and Noncompetitive Inhibition of Myocardial Cytochrome C Oxidase in Sepsis

C. Deutschman, N. Avadhani, C. Vijayasarathy, 2002, Shock.

A proposed role for 5S ribosomal RNA.

D. E. Buetow, N. Avadhani, 1973, Biochemical and biophysical research communications.

Identification of a transcriptional initiator element in the cytochrome c oxidase subunit Vb promoter which binds to transcription factors NF-E1 (YY-1, delta) and Sp1.

M. Atchison, N. Avadhani, K. Park, 1993, The Journal of biological chemistry.

Reversal of amphetamine induced polysome dissociation by neuroleptic agents in rat brain.

N. Avadhani, M. Widelitz, M. R. Coryell, 1977, Biochemical and biophysical research communications.

Analysis of the RNA of Euglena gracilis on polyacrylamide gels

D. E. Buetow, N. Avadhani, K. Schuit, 2004, Archiv für Mikrobiologie.

Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection.

A. Kashina, S. Srinivasan, M. Guha, 2017, Biochimica et biophysica acta. Bioenergetics.

Function of Mitochondrial Stat3 in Cellular Respiration

P. Fawcett, Xin-Yuan Fu, D. Baker, 2009, Science.

Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap.

B. Kalyanaraman, S. Srinivasan, N. Avadhani, 2007, Chemical research in toxicology.

Tissue specificity of mitochondrial monooxygenase system for aflatoxin B1 activation.

N. Avadhani, B. G. Niranjan, 1980, Biochemical and biophysical research communications.

Differences in activity of cytochrome C oxidase in brain between sleep and wakefulness.

Allan I Pack, A. Pack, N. Avadhani, 2005, Sleep.

Mitochondrial Targeted Cytochrome P450 2E1 (P450 MT5) Contains an Intact N Terminus and Requires Mitochondrial Specific Electron Transfer Proteins for Activity*

L. Otvos, M. Cudic, M. Robin, 2001, The Journal of Biological Chemistry.

Cytochrome c oxidase dysfunction in oxidative stress.

S. Srinivasan, N. Avadhani, 2012, Free radical biology & medicine.

EFFECTS OF AMPHETAMINE ADMINISTRATION IN VIVO ON IN VITRO PROTEIN SYNTHESIZING SYSTEM FROM RAT BRAIN 1

N. Avadhani, M. Widelitz, M. R. Coryell, 1976, Journal of neurochemistry.

Dissociation of rat brain polyribosomesin vivo by amphetamines

N. Avadhani, M. Widelitz, M. R. Coryell, 1975, Brain Research.

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

M. Robin, N. Avadhani, G. Biswas, 2003, The Journal of cell biology.

Messenger ribonucleic acid metabolism in mammalian mitochondria. Origin of ethidium bromide resistant poly(adenylic acid) containing ribonucleic acid in Ehrlich ascites mitochondria.

N. Avadhani, R. Rutman, N. Battula, 1973, Biochemistry.

Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter‐organelle crosstalk

B. Freedman, M. Zaidi, N. Avadhani, 1999, The EMBO journal.

Differential effects of ethidium bromide on cytoplasmic and mitochondrial protein synthesis

N. Avadhani, R. Rutman, 1975, FEBS letters.

Transcription termination at the mouse mitochondrial H-strand promoter distal site requires an A/T rich sequence motif and sequence specific DNA binding proteins.

N. Avadhani, Ji-Kang Fang, V. Camasamudram, 2003, European journal of biochemistry.

Messenger ribonucleic acid metabolism in mammalian mitochondria. Quantitative aspects of structural information coded by the mitochondrial genome.

N. Avadhani, R. Rutman, F. S. Lewis, 1974, Biochemistry.

A sensitive in vitro protein synthesizing system from Ehrlich ascites mitochondria.

N. Avadhani, R. Rutman, 1974, Biochemical and biophysical research communications.

Poly adenylic acid sequences in mitochondrial RNA.

N. Avadhani, R. Rutman, M. Kuan, 1973, Biochemical and biophysical research communications.

A rat liver RNA-DNA-protein complex with template activity for protein synthesis.

D. E. Buetow, N. Avadhani, D. H. Roe, 1971, Biochimica et biophysica acta.

Inhibition of mitochondrial protein synthesis during early stages of aflatoxin B1-induced hepatocarcinogenesis.

N. Avadhani, B. G. Niranjan, N. K. Bhat, 1982, Cancer research.

Mitochondrial retrograde signaling induces epithelial–mesenchymal transition and generates breast cancer stem cells

R. Carstens, G. Ruthel, C. Khanna, 2014, Oncogene.

Blocking FSH induces thermogenic adipose tissue and reduces body fat

T. Yuen, S. Izadmehr, Z. Bian, 2017, Nature.

Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain*

N. Avadhani, H. Anandatheerthavarada, B. M. Prabhu, 2008, Journal of Biological Chemistry.

Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.

N. Sondheimer, M. Guha, N. Avadhani, 2010, Biochimica et biophysica acta.

Activation of a Novel Calcineurin-mediated Insulin-like Growth Factor-1 Receptor Pathway, Altered Metabolism, and Tumor Cell Invasion in Cells Subjected to Mitochondrial Respiratory Stress*

S. Srinivasan, M. Guha, N. Avadhani, 2007, Journal of Biological Chemistry.

Stimulation of transcription and translation by aurin tricarboxylic acid in mitochondrial lysates from Ehrlich ascites cells.

N. Avadhani, B. G. Niranjan, G. Kantharaj, 1987, Biochemical and biophysical research communications.

Additive Effects of Mitochondrion-targeted Cytochrome CYP2E1 and Alcohol Toxicity on Cytochrome c Oxidase Function and Stability of Respirosome Complexes*

J. Joseph, B. Kalyanaraman, S. Bansal, 2012, The Journal of Biological Chemistry.

Role of nuclear-encoded subunit Vb in the assembly and stability of cytochrome c oxidase complex: implications in mitochondrial dysfunction and ROS production.

B. Kalyanaraman, D. Galati, S. Srinivasan, 2009, The Biochemical journal.

Mitochondrial signaling: the retrograde response.

N. Avadhani, R. A. Butow, Ronald A Butow, 2004, Molecular cell.

Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance

S. Natsugoe, A. Rustgi, H. Nakagawa, 2017, Oncogene.

Novel biochemical and functional insights into nuclear Ca(2+) transport through IP(3)Rs and RyRs in osteoblasts.

Li Sun, M. Zaidi, N. Avadhani, 2000, American journal of physiology. Renal physiology.

Aggressive triple negative breast cancers have unique molecular signature on the basis of mitochondrial genetic and functional defects.

Deanne M. Taylor, R. Carstens, P. Raman, 2018, Biochimica et biophysica acta. Molecular basis of disease.

Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors.

G. Mills, A. Weeraratna, K. Flaherty, 2016, The Journal of clinical investigation.

Mechanism of mitochondrial stress-induced resistance to apoptosis in mitochondrial DNA-depleted C2C12 myocytes

N. Avadhani, G. Biswas, H. Anandatheerthavarada, 2005, Cell Death and Differentiation.

Mitochondria‐to‐nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

G. Amuthan, A. Klein-Szanto, N. Avadhani, 2001, The EMBO journal.

Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells

G. Ginsberg, A. Bass, S. Natsugoe, 2018, Cellular and molecular gastroenterology and hepatology.

Mitochondrial Targeting of Cytochrome P450 Proteins Containing NH2-terminal Chimeric Signals Involves an Unusual TOM20/TOM22 Bypass Mechanism*

N. B. Sepuri, N. Avadhani, H. Anandatheerthavarada, 2009, The Journal of Biological Chemistry.

Bimodal protein targeting through activation of cryptic mitochondrial targeting signals by an inducible cytosolic endoprotease.

S. Srinivasan, N. Avadhani, Ji-Kang Fang, 2008, Molecular cell.

An Unusual TOM20/TOM22 Bypass Mechanism for the Mitochondrial Targeting of Cytochrome P450 Proteins Containing N-terminal Chimeric Signals*

N. B. Sepuri, N. Avadhani, G. Biswas, 2008, Journal of Biological Chemistry.

Accumulation of Amyloid Precursor Protein in the Mitochondrial Import Channels of Human Alzheimer’s Disease Brain Is Associated with Mitochondrial Dysfunction

D. Galati, N. Avadhani, Latha Devi, 2006, The Journal of Neuroscience.

Structural organization and transcription regulation of nuclear genes encoding the mammalian cytochrome c oxidase complex.

N. Lenka, N. Avadhani, C. Vijayasarathy, 1998, Progress in nucleic acid research and molecular biology.

Regulation of Murine Cytochrome Oxidase Vb Gene Expression in Different Tissues and during Myogenesis

N. Lenka, N. Avadhani, A. Basu, 1997, The Journal of Biological Chemistry.

The Role of an E Box Binding Basic Helix Loop Helix Protein in the Cardiac Muscle-specific Expression of the Rat Cytochrome Oxidase Subunit VIII Gene*

N. Lenka, N. Avadhani, A. Basu, 1996, The Journal of Biological Chemistry.

Cloning and characterization of the mouse cytochrome c oxidase subunit IV gene.

N. Avadhani, R. S. Carter, Narayan G. Avadhani, 1991, Archives of biochemistry and biophysics.

Variations in the subunit content and catalytic activity of the cytochrome c oxidase complex from different tissues and different cardiac compartments.

I. Hall, I. Biunno, N. Lenka, 1998, Biochimica et biophysica acta.

Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.

M. Guha, N. Avadhani, Manti Guha, 2013, Mitochondrion.

Qualitative and comparative nature of mitochondrial translation products in mammalian cells.

N. Avadhani, B. G. Niranjan, N. K. Bhat, 1982, Biochemistry.

Heterogeneous nuclear ribonucleoprotein A2 is a common transcriptional coactivator in the nuclear transcription response to mitochondrial respiratory stress.

M. Guha, N. Avadhani, Hua Pan, 2009, Molecular biology of the cell.

Mitochondrial genome and functional defects in osteosarcoma are associated with their aggressive phenotype

S. Srinivasan, M. Guha, N. Avadhani, 2018, PloS one.

Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2

M. Birnbaum, M. Guha, N. Avadhani, 2010, Molecular biology of the cell.

A Distinctive Physiological Role for IκBβ in the Propagation of Mitochondrial Respiratory Stress Signaling*

N. Sondheimer, S. Bansal, M. Guha, 2008, Journal of Biological Chemistry.

A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP‐ribosyl cyclase, a putative intracellular NAD+ sensor

Li Sun, M. Zaidi, A. Koval, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition

G. Ruthel, H. Nakagawa, T. Kijima, 2019, Oncotarget.

Evolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact points

M. Waterman, G. Amuthan, R. Murali, 2001, The EMBO journal.

The transport and processing of carbamyl phosphate synthetase-I in mouse hepatic mitochondria.

N. Avadhani, N. K. Bhat, 1984, Biochemical and biophysical research communications.

hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction

G. Ruthel, M. García-Díaz, T. Kundu, 2018, PloS one.

Silencing of IkBβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo.

A. Rustgi, Li Huang, A. Chowdhury, 2012, Carcinogenesis.

Silencing of I k B β mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo

A. Rustgi, Li Huang, A. Chowdhury, 2012 .

Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression

H. Nakagawa, D. S. St. Clair, Kazuhide Yamamoto, 2014, Oncogene.

Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury

H. Rui, A. Rustgi, Angela K. Brice, 2014, EMBO molecular medicine.

Localization of multiple forms of inducible cytochromes P450 in rat liver mitochondria: immunological characteristics and patterns of xenobiotic substrate metabolism.

S. Addya, N. Avadhani, G. Biswas, 1997, Archives of biochemistry and biophysics.

Constitutive and inducible cytochromes P450 in rat lung mitochondria: xenobiotic induction, relative abundance, and catalytic properties.

N. Avadhani, H. Raza, J. Mullick, 1999, Toxicology and applied pharmacology.

Mitochondria‐Targeted Cytochromes P450 Modulate Adverse Drug Metabolism and Xenobiotic‐Induced Toxicity

N. Avadhani, H. Raza, F. Guengerich, 2018 .

Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicity

S. Bansal, N. Avadhani, M. C. Sangar, 2010, Expert opinion on drug metabolism & toxicology.

Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

E. Rappaport, G. Ruthel, F. Johnson, 2019, Cell Discovery.

CHAPTER 7 – POLYRIBOSOMES, RIBOSOMES, AND RIBOSOMAL RNA

G. Freyssinet, N. Avadhani, 1989 .

Isolation of active polyribosomes from the cytoplasm, mitochondria and chloroplasts of Euglena gracilis.

D. E. Buetow, N. Avadhani, 1972, The Biochemical journal.

Protein synthesis with isolated mitochondrial polysomes.

D. E. Buetow, N. Avadhani, 1972, Biochemical and biophysical research communications.

Mitochondria to nucleus stress signaling

M. Zaidi, N. Avadhani, G. Biswas, 2003, Journal of Cell Biology.

Knock-In Mouse Lines Expressing either Mitochondrial or Microsomal CYP1A1: Differing Responses to Dietary Benzo[a]pyrene as Proof of Principle

D. Nebert, Zhanquan Shi, T. Dalton, 2009, Molecular Pharmacology.

Targeting of Splice Variants of Human Cytochrome P450 2C8 (CYP2C8) to Mitochondria and Their Role in Arachidonic Acid Metabolism and Respiratory Dysfunction*

P. Bajpai, S. Srinivasan, N. Avadhani, 2014, The Journal of Biological Chemistry.

Dual Targeting Property of the N-terminal Signal Sequence of P4501A1

S. Addya, W. Pandak, N. Avadhani, 1999, The Journal of Biological Chemistry.

Site specific phosphorylation of cytochrome c oxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion

D. Galati, N. Avadhani, H. Raza, 2007, FEBS letters.

Mitochondrial Respiratory Stress Cell Invasion in Cells Subjected to Pathway, Altered Metabolism, and Tumor Insulin-like Growth Factor-1 Receptor Activation of a Novel Calcineurin-mediated Metabolism and Bioenergetics:

S. Srinivasan, M. Guha, N. Avadhani, 2014 .

Dysregulation of RyR Calcium Channel Causes the Onset of Mitochondrial Retrograde Signaling

G. Hajnóczky, G. Csordás, S. Srinivasan, 2020, iScience.

Mitochondria-targeted heme oxygenase-1 induces oxidative stress and mitochondrial dysfunction in macrophages, kidney fibroblasts and in chronic alcohol hepatotoxicity

S. Bansal, N. Avadhani, G. Biswas, 2013, Redox biology.

Function of Mitochondrial Stat 3 in Cellular Respiration

P. Fawcett, Xin-Yuan Fu, D. Baker, 2022 .

Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells

G. Amuthan, N. Avadhani, C. Vijayasarathy, 2002, Oncogene.

Roles of Cytochrome P450 in Metabolism of Ethanol and Carcinogens.

N. Avadhani, F. Peter Guengerich, 2018, Advances in experimental medicine and biology.

Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models

E. Radaelli, A. Chowdhury, N. Avadhani, 2019, The Journal of Biological Chemistry.

Bimodal Targeting of Microsomal CYP2E1 to Mitochondria through Activation of an N-terminal Chimeric Signal by cAMP-mediated Phosphorylation*

D. Pain, N. B. Sepuri, M. Robin, 2002, The Journal of Biological Chemistry.

Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon

R. Hartley, M. Murphy, B. Kalyanaraman, 2020, Redox biology.

Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Mitochondrion-targeted Cytochrome P450 2D6

F. Guengerich, G. Chowdhury, P. Bajpai, 2012, The Journal of Biological Chemistry.

The complexity of mitochondrial translation products in mammalian cells.

N. Avadhani, B. G. Niranjan, N. K. Bhat, 1981, Biochemical and biophysical research communications.

Inhibition of mitochondrial translation by calmodulin antagonist N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide.

N. Avadhani, H. Raza, C. Vijayasarathy, 1993, Biochimica et biophysica acta.

Expression of the cytochrome b-URF6-URF5 region of the mouse mitochondrial genome.

N. Avadhani, N. K. Bhat, A. Iyengar, 1985, Biochemistry.

Mitochondrial LON protease-dependent degradation of cytochrome c oxidase subunits under hypoxia and myocardial ischemia.

N. B. Sepuri, S. Srinivasan, M. Guha, 2017, Biochimica et biophysica acta. Bioenergetics.

Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signaling

S. Srinivasan, N. Avadhani, G. Biswas, 2008, Proceedings of the National Academy of Sciences.

β-Naphthoflavone-Induced Mitochondrial Respiratory Damage in Cyp1 Knockout Mouse and in Cell Culture Systems: Attenuation by Resveratrol Treatment

N. A. Leu, S. Bansal, A. Chowdhury, 2017, Oxidative medicine and cellular longevity.

Characterization of primary transcripts and identification of transcription initiation sites on the heavy and light strands of mouse mitochondrial DNA.

N. Avadhani, N. Avdalovic, K. Bhat, 1989, Biochemistry.

Canine mitochondrial myopathy associated with reduced mitochondrial mRNA and altered cytochrome c oxidase activities in fibroblasts and skeletal muscle.

U. Giger, N. Avadhani, E. Breitschwerdt, 1994, Comparative biochemistry and physiology. Part A, Physiology.

Functional characterization of a human DNase-like protein encoded by a gene positioned in Xq28.

V. Sgaramella, I. Biunno, N. Avadhani, 1997, Gene.

Characterization of a female-specific hepatic mitochondrial cytochrome P-450 whose steady-state level is modulated by testosterone.

S. Addya, N. Avadhani, R. Shayiq, 1991, Biochemistry.

HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

E. Rappaport, G. Ruthel, F. Johnson, 2016, Cell Discovery.

HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

E. Rappaport, G. Ruthel, F. Johnson, 2016, Cell Discovery.

Nature of steady-state and newly synthesized mitochondrial messenger ribonucleic acids in mouse liver and Ehrlich ascites tumor cells.

N. Avadhani, G. Kantharaj, K. Bhat, 1984, Biochemistry.

Purification and characterization of a hepatic mitochondrial cytochrome P-450 active in aflatoxin B1 metabolism.

N. Avadhani, R. Shayiq, Narayan G. Avadhani, 1989, Biochemistry.

Mitochondrial Glutathione S-Transferase Pool in Health and Disease

N. Avadhani, H. Raza, 2006 .

Purification and characterization of a hepatic mitochondrial glutathione S-transferase exhibiting immunochemical relationship to the alpha-class of cytosolic isoenzymes.

S. Addya, N. Avadhani, J. Mullick, 1994, Archives of biochemistry and biophysics.

Intramitochondrial fatty acylation of a cytoplasmic imported protein in animal cells.

N. Bhat, N. Avadhani, C. Vijayasarathy, 1989, The Journal of biological chemistry.

Hepatic mitochondrial cytochrome P-450 system. Identification and characterization of a precursor form of mitochondrial cytochrome P-450 induced by 3-methylcholanthrene.

C. Jefcoate, N. Avadhani, H. Raza, 1988, The Journal of biological chemistry.

Messenger ribonucleic acid metabolism in mammalian mitochondria. Discrete poly(adenylic acid) lacking messenger ribonucleic acid species associated with mitochondrial polysomes.

N. Avadhani, R. Rutman, F. S. Lewis, 1976, Biochemistry.

Dysregulation of ezrin phosphorylation prevents metastasis and alters cellular metabolism in osteosarcoma.

J. Khan, Qingrong Chen, C. Khanna, 2012, Cancer research.

Disruption of Cytochrome c Oxidase Function Induces Warburg Effect and Metabolic Reprogramming

S. Natsugoe, G. Ruthel, H. Nakagawa, 2015, Oncogene.

Physical Interaction and Functional Synergy between Glucocorticoid Receptor and Ets2 Proteins for Transcription Activation of the Rat Cytochrome P-450c27 Promoter*

N. Bhat, N. Avadhani, G. Biswas, 2001, The Journal of Biological Chemistry.

Nucleotide sequence of cDNA for nuclear encoded subunit Vb of mouse cytochrome-c oxidase.

N. Avadhani, A. Basu, 1990, Biochimica et biophysica acta.

Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages

T. Yuen, S. Fuchs, T. Kijima, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection.

A. Kashina, S. Srinivasan, N. Avadhani, 2017, Biochimica et biophysica acta. Bioenergetics.

Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1

N. Avadhani, S. Yadav, H. Anandatheerthavarada, 2007, The FEBS journal.

Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.

N. Sondheimer, N. Avadhani, Weigang Tang, 2010, Biochimica et biophysica acta.

Cytochrome c oxidase dysfunction in oxidative stress.

S. Srinivasan, N. Avadhani, 2012, Free radical biology & medicine.

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

M. Robin, N. Avadhani, G. Biswas, 2003, The Journal of cell biology.

Purification and characterization of dicyclohexylcarbodiimide binding protein from mouse liver mitochondria.

N. Avadhani, V. A. Aroskar, 1979, Biochemical and biophysical research communications.

Mitochondrial RNA and protein metabolism.

N. Avadhani, R. Rutman, F. S. Lewis, 1976, Sub-cellular biochemistry.

Activation of aflatoxin B1 by a mono-oxygenase system localized in rat liver mitochondria.

N. Avadhani, B. G. Niranjan, 1980, The Journal of biological chemistry.