R. Carroll

发表

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

J. Orange, C. June, Jeffrey C. Miller, 2008, Nature Biotechnology.

Vascular leukocytes contribute to tumor vascularization.

G. Coukos, R. Buckanovich, S. Rubin, 2005, Blood.

A trial of intrapleural adenoviral-mediated Interferon-α2b gene transfer for malignant pleural mesothelioma.

Sharyn I. Katz, D. Heitjan, L. Montaner, 2011, American journal of respiratory and critical care medicine.

Suppression of HIV-1 infection in primary CD4 T cells transduced with a self-inactivating lentiviral vector encoding a membrane expressed gp41-derived fusion inhibitor.

C. June, D. von Laer, J. Riley, 2005, Clinical immunology.

Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules.

C. June, J. Riley, T. Golovina, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

PHOSPHATIDYLINOSITOL 3-KINASE IS REQUIRED FOR PROLIFERATION AND MIGRATION OF HUMAN PULMONARY VASCULAR SMOOTH MUSCLE CELLS

A. Ammit, E. Goncharova, A. Eszterhas, 2002 .

PI 3 K is required for proliferation and migration of human pulmonary vascular smooth muscle cells

A. Ammit, E. Goncharova, A. Eszterhas, 2002 .

Signal transduction through crosslinking CD7 and IgM-Fc receptors that inhibits T-cell proliferation.

R. Carroll, M. Emara, 1992, Human immunology.

CD28 Costimulation Is Essential for Human T Regulatory Expansion and Function1

B. Levine, C. June, B. Blazar, 2008, The Journal of Immunology.

T Regulatory Expansion and Function CD 28 Costimulation Is Essential for Human June and

B. Levine, C. June, B. Blazar, 2008 .

of Human Disseminated Tumor Expressing a Chimeric Antigen Receptor Mediate Regression Multiple Injections of Electroporated Autologous T Cells

Xiaojun Liu, S. Albelda, E. Moon, 2010 .

A Phase I Trial of Repeated Intrapleural Adenoviral-mediated Interferon-β Gene Transfer for Mesothelioma and Metastatic Pleural Effusions.

Sharyn I. Katz, D. Heitjan, C. June, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma

C. June, Tomoyuki N. Tanaka, D. Sterman, 2005, Cancer biology & therapy.

Immunometabolism around the Clock.

O. Kennedy, Annie M Curtis, Mariana P. Cervantes-Silva, 2019, Trends in molecular medicine.

Intrinsic resistance to T cell infection with HIV type 1 induced by CD28 costimulation.

B. Levine, C. June, O. Weislow, 1997, Journal of immunology.

Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells.

B. Levine, C. June, O. Weislow, 1997, Science.

Cancer esearch oenvironment and Immunology tiple Injections of Electroporated Autologous T Cells ressing a Chimeric Antigen Receptor Mediate R ression of Human Disseminated Tumor

C. June, Xiaojun Liu, S. Albelda, 2010 .

Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.

D. Campana, D. Teachey, J. Fish, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Single-Dose Intrapleural IFN-B GeneTransfer forMalignant PleuralMesotheliomaandMetastatic Pleural Effusions : HighRate ofAntitumor ImmuneResponses

Mitchell Ho, I. Pastan, D. Heitjan, 2007 .

A Phase I Clinical Trial of Single-Dose Intrapleural IFN-β Gene Transfer for Malignant Pleural Mesothelioma and Metastatic Pleural Effusions: High Rate of Antitumor Immune Responses

Mitchell Ho, I. Pastan, D. Heitjan, 2007, Clinical Cancer Research.

Intertwining roles of circadian and metabolic regulation of the innate immune response

Annie M Curtis, James R. O’Siorain, R. Carroll, 2022, Seminars in Immunopathology.

TCancer Patients Directly Inhibit Autologous Cutting Edge : Regulatory T Cells from Lung

C. June, L. Kaiser, J. Riley, 2002 .

An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation

Emma L. Koppe, L. O’Neill, D. Sévin, 2018, The Journal of Biological Chemistry.

TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients.

G. Coukos, B. Levine, C. June, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Dendritic cell-activated CD44hiCD8+ T cells are defective in mediating acute graft-versus-host disease but retain graft-versus-leukemia activity.

B. Levine, C. June, Jiang Zhu, 2004, Blood.

Autophagy in multiple myeloma: what makes you stronger can also kill you.

Seamus J. Martin, R. Carroll, 2013, Cancer cell.

acute graft-versus-host disease but retain graft-versus-leukemia activity activated CD44hiCD8+ T cells are defective in mediating - Dendritic cell

B. Levine, C. June, Jiang Zhu, 2013 .

Programming the next generation of dendritic cells.

C. June, R. Carroll, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Productive Infection of Neonatal CD 8 1 T Lymphocytes by HIV-1 By

J. Hoxie, C. June, R. Hodes, 1998 .

TRANCE-and CD 40 Ligand-matured Dendritic Cells Reveal MHC Class I-restricted T Cells Specific for Autologous Tumor in Late-Stage Ovarian Cancer Patients 1

G. Coukos, B. Levine, C. June, 2003 .

Interferon β adenoviral gene therapy in a patient with ovarian cancer

G. Coukos, C. June, D. Sterman, 2006, Nature Clinical Practice Oncology.

Influenza virus upregulates CXCR4 expression in CD4+ cells.

P. Rose, R. Blumenthal, A. Puri, 2000, AIDS research and human retroviruses.

Aging alters rhythms in immunity

Annie M Curtis, R. Carroll, Annie M. Curtis, 2022, Nature Immunology.

Response from Carroll et al.

B. Levine, C. June, J. Riley, 1997 .

Cell Proliferation T Cancer Patients Directly Inhibit Autologous Cutting Edge: Regulatory T Cells from Lung

C. June, J. Riley, H. Yeh, 2013 .

Characterization of a Human Stromal Cell Line Supporting Hematopoietic Progenitor Cell Proliferation: Effect of HIV Expression.

E. Terwilliger, J. Mosca, V. L. La Russa, 1995, Journal of biomedical science.

Brief report Vascular leukocytes contribute to tumor vascularization

G. Coukos, R. Buckanovich, S. Rubin, 2004 .

Malonylation of GAPDH is an in ﬂ ammatory signal in macrophages

A. Nadin, M. Haneklaus, M. Murphy, 2019 .

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Edward T Chouchani, John Szpyt, Mark P. Jedrychowski, 2018, Nature.

Intertwining roles of circadian and metabolic regulation of the innate immune response

James R. O’Siorain, R. Carroll, Lauren E. Fagan, 2022, Seminars in Immunopathology.

Tumor-associated macrophages as a source of functional dendritic cells in ovarian cancer patients.

C. June, S. Rubin, R. Carroll, 2002, Clinical immunology.

Interferon Administered in the Cerebrospinal Space and Its Effect on Rabies in Rabbits

J. Armstrong, R. Carroll, M. Ho, 1974, Infection and immunity.

Treatment of advanced leukemia in mice with mRNA engineered T cells.

S. Grupp, M. Kalos, C. June, 2011, Human gene therapy.

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

I. Pastan, D. Heitjan, C. June, 2009, Proceedings of the National Academy of Sciences.

Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load.

Richard Carroll, Bruce L Levine, Boro Dropulic, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

Inflammasome Priming in Sterile Inflammatory Disease.

Seth L Masters, C. Bryant, S. Masters, 2017, Trends in molecular medicine.

Immunosurveillance and survivin-specific T-cell immunity in children with high-risk neuroblastoma.

G. Pinkus, M. Fleming, J. Maris, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Bcl-2 family proteins participate in mitochondrial quality control by regulating Parkin/PINK1-dependent mitophagy.

S. Cullen, Seamus J. Martin, R. Carroll, 2014, Molecular cell.

Adoptive immunotherapy: good habits instilled at youth have long-term benefits

Bruce L. Levine, Gabriela Plesa, Chrystal M. Paulos, 2008, Immunologic research.

Multiple initial culture conditions enhance the establishment of cell lines from primary ovarian cancer specimens

B. Weber, Jia Huang, Xiaochuan Shan, 2006, In Vitro Cellular & Developmental Biology - Animal.

Parkin sensitizes toward apoptosis induced by mitochondrial depolarization through promoting degradation of Mcl-1.

Seamus J. Martin, R. Carroll, E. Hollville, 2014, Cell reports.

Large-scale production of CD4+ T cells from HIV-1-infected donors after CD3/CD28 costimulation.

J L Riley, R G Carroll, B L Levine, 1998, Journal of hematotherapy.

Antiviral Effect and Ex Vivo CD4+ T Cell Proliferation in HIV-Positive Patients as a Result of CD28 Costimulation

Bruce L. Levine, Maryanne T. Vahey, Donald S. Burke, 1996, Science.

Cutting Edge: Regulatory T Cells from Lung Cancer Patients Directly Inhibit Autologous T Cell Proliferation1

C. June, L. Kaiser, J. Riley, 2002, The Journal of Immunology.

Tat-Associated Kinase, TAK, Activity Is Regulated by Distinct Mechanisms in Peripheral Blood Lymphocytes and Promonocytic Cell Lines

A. Rice, R. Carroll, C. H. Herrmann, 1998, Journal of Virology.

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5.

Gabriela Plesa, Bruce L Levine, James L Riley, 2013, Human gene therapy.

Genetic engineering of T cells for adoptive immunotherapy

Michael Milone, Carl H. June, James L. Riley, 2008, Immunologic research.

Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons.

M. Connors, D. Birx, B. Levine, 2004, Clinical immunology.

Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection

D. Birx, B. Levine, C. June, 2002, Nature Medicine.

Modulation of Susceptibility to HIV-1 Infection by the Cytotoxic T Lymphocyte Antigen 4 Costimulatory Molecule

P. Blair, C. June, B. Carreno, 2000, The Journal of experimental medicine.

Naı̈ve and Memory CD4 T Cells Differ in Their Susceptibilities to Human Immunodeficiency Virus Type 1 Infection following CD28 Costimulation: Implications for Transmission and Pathogenesis

B. Levine, C. June, J. Riley, 1998, Journal of Virology.

Productive Infection of Neonatal Cd8 Ϩ T Lymphocytes by Hiv-1

Carl H. June, James L. Riley, J. Hoxie, 2022 .

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

R. Phillips, C. June, A. Sewell, 2008, Nature Medicine.

The Inducible Costimulator (ICOS) Is Critical for the Development of Human TH17 Cells

C. June, J. Riley, T. Golovina, 2010, Science Translational Medicine.

Malonylation of GAPDH is an inflammatory signal in macrophages

A. Nadin, M. Haneklaus, M. Murphy, 2019, Nature Communications.

Caspase-11 promotes allergic airway inflammation

T. Greulich, B. Schmeck, J. Kearney, 2020, Nature Communications.

The role of co-stimulation in regulation of chemokine receptor expression and HIV-1 infection in primary T lymphocytes.

P. Blair, B. Levine, C. June, 1998, Seminars in immunology.

Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL-18

P. Gimotty, G. Coukos, D. Powell, 2009, Journal of Translational Medicine.

Constitutive noncanonical NFκB signaling in pancreatic cancer cells

M. May, R. Carroll, C. Wharry, 2009, Cancer biology & therapy.

Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor.

B. Levine, C. June, Xiaojun Liu, 2010, Cancer research.

ression of Human Disseminated Tumor

C. June, Xiaojun Liu, S. Albelda, 2010 .

PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells.

Reynold A Panettieri, Elena A Goncharova, A. Ammit, 2002, American journal of physiology. Lung cellular and molecular physiology.

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2

Darren J. Fitzpatrick, Daniel J. O'Connell, R. Xavier, 2018, Proceedings of the National Academy of Sciences.

Malonylation of GAPDH is an inflammatory signal in macrophages

A. Nadin, M. Haneklaus, M. Murphy, 2019, Nature Communications.

The Circadian Clock Protein BMAL1 Acts as a Metabolic Sensor In Macrophages to Control the Production of Pro IL-1β

Mariana P. Cervantes-Silva, George A. Timmons, James R. O’Siorain, 2021, Frontiers in Immunology.

Caspase-11 promotes allergic airway inflammation

T. Greulich, B. Schmeck, J. Kearney, 2020, Nature Communications.

Distinct Effects of IL-18 on the Engraftment and Function of Human Effector CD8+ T Cells and Regulatory T Cells

G. Coukos, C. June, S. Albelda, 2008, PloS one.

The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing

David K. Finlay, K. Mills, Mariana P. Cervantes-Silva, 2022, Nature Communications.

Circadian disruption in lung fibroblasts enhances NF‐κB activity to exacerbate neutrophil recruitment

G. FitzGerald, James R. O’Siorain, R. Carroll, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions.

Sharyn I. Katz, D. Heitjan, C. June, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

CellsHHuman T The Inducible Costimulator ( ICOS ) Is Critical for the Development of

C. June, J. Riley, T. Golovina, 2010 .

Mode of Transmission Affects the Sensitivity of Human Immunodeficiency Virus Type 1 to Restriction by Rhesus TRIM5α

Joseph Sodroski, Nikolay Korokhov, Guido Silvestri, 2008, Journal of Virology.

CD28 co-receptor signal transduction in T-cell activation.

P J Blair, J L Riley, R G Carroll, 1997, Biochemical Society transactions.

Inflammasome Priming in Sterile Inflammatory Disease.

C. Bryant, S. Masters, K. Triantafilou, 2017, Trends in molecular medicine.

Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.

D. Campana, D. Teachey, J. Fish, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

John Szpyt, Mark P. Jedrychowski, R. Fischer, 2018, Nature.

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

C. June, A. Sewell, M. Purbhoo, 2008, Nature Medicine.

Productive Infection of Neonatal CD8+ T Lymphocytes by HIV-1

J. Hoxie, C. June, R. Hodes, 1998, The Journal of experimental medicine.

Adoptive immunotherapy: good habits instilled at youth have long-term benefits

B. Levine, C. June, J. Riley, 2008, Immunologic research.

Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL-18

P. Gimotty, G. Coukos, C. June, 2009, Journal of Translational Medicine.

Autophagy in multiple myeloma: what makes you stronger can also kill you.

Seamus J. Martin, R. Carroll, 2013, Cancer cell.