G. Gillespie

发表

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

B. Korber, L. Picker, A. McMichael, 2016, Science.

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

D. Richman, P. Klenerman, S. Rowland-Jones, 2002, Nature Medicine.

HIV-Specific Cd8+ T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function

Douglas D. Richman, Tao Dong, Victor Appay, 2000, The Journal of experimental medicine.

Some lessons from the systematic production and structural analysis of soluble (alpha)(beta) T-cell receptors.

S. Sainsbury, R. Owens, D. Stuart, 2009, Journal of immunological methods.

Cutting Edge: Allele-Specific and Peptide-Dependent Interactions between KIR3DL1 and HLA-A and HLA-B12

M. Carrington, S. Rowland-Jones, P. Parham, 2007, The Journal of Immunology.

Direct visualization and quantitation of cytomegalovirus-specific CD8+ cytotoxic T-lymphocytes in liver transplant patients.

D. Pillay, J. Ainsworth, D. Mutimer, 2000, Transplantation.

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57

Tao Dong, Andrew J. McMichael, Tim Peto, 2002, AIDS.

Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8+ T cell antiviral responses.

C. Brander, V. Miller, T. Peto, 2021, Cell reports.

Detailed and atypical HLA-E peptide binding motifs revealed by a novel peptide exchange binding assay

A. McMichael, G. Gillespie, L. Walters, 2020, bioRxiv.

Detailed and atypical HLA‐E peptide binding motifs revealed by a novel peptide exchange binding assay

A. McMichael, G. Gillespie, L. Walters, 2020, European journal of immunology.

Functional Differences Exist between TNFα Promoters Encoding the Common −237G SNP and the Rarer HLA-B*5701-Linked A Variant

J. Knight, S. Rowland-Jones, A. McMichael, 2012, PloS one.

Tetrameric HLA class I–minor histocompatibility antigen peptide complexes demonstrate minor histocompatibility antigen-specific cytotoxic T lymphocytes in patients with graft-versus-host disease

P. Moss, T. Mutis, G. Gillespie, 1999, Nature Medicine.

Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes

A. McMichael, R. Rambo, E. Jones, 2022, Cell reports.

Lack of KIR3DS1 binding to MHC class I Bw4 tetramers in complex with CD8+ T cell epitopes.

M. Carrington, S. Rowland-Jones, T. Dong, 2007, AIDS research and human retroviruses.

An unbiased characterization of the HLA-E and CD94/NKG2x peptide repertoire reveals peptide ligands that skew NK cell activation

A. McMichael, M. Birnbaum, Brooke D. Huisman, 2022, bioRxiv.

HLA class I-minor histocompatibility antigen tetramers select cytotoxic T cells with high avidity to the natural ligand.

P. Moss, T. Mutis, G. Gillespie, 2000, The hematology journal : the official journal of the European Haematology Association.

Associated with Long-Term Nonprogression Identification of Related HLAs Potentially HLA-B * 5703-Peptide Complexes and Structures of Three HIV-1

R. Kaul, S. Rowland-Jones, P. Roche, 2005 .

Multiple T cell expansions are found in the blood and synovial fluid of patients with reactive arthritis.

A. McMichael, P. Bowness, Bryan Paul Wordsworth, 1997, The Journal of rheumatology.

Differentiation of Cytomegalovirus-specific Cd8

Ozdemir, Green, H. Fernandez, 2022 .

Cytomegalovirus reactivation following allogeneic stem cell transplantation is associated with the presence of dysfunctional antigen-specific CD8+ T cells.

S. Rowland-Jones, R. Champlin, K. Komanduri, 2002, Blood.

Gonococcal cervicitis is associated with reduced systemic CD8+ T cell responses in human immunodeficiency virus type 1-infected and exposed, uninfected sex workers.

R. Kaul, S. Rowland-Jones, A. McMichael, 2002, The Journal of infectious diseases.

T cells + antigen-specific CD 8 transplantation is associated with the presence of dysfunctional Cytomegalovirus reactivation following allogeneic stem cell

R. Champlin, K. Komanduri, G. Gillespie, 2002 .

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

L. Picker, A. McMichael, P. Borrow, 2018, Nature Communications.

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

B. Haynes, A. McMichael, P. Borrow, 2020, Communications Biology.

Large clonal expansions of CD8+ T cells in acute infectious mononucleosis

J. Bell, A. McMichael, P. Moss, 1996, Nature Medicine.

HLA-E–restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities

L. Picker, A. McMichael, P. Borrow, 2021, Science Immunology.

An Early HIV Mutation within an HLA-B*57-Restricted T Cell Epitope Abrogates Binding to the Killer Inhibitory Receptor 3DL1

T. Schumacher, A. McMichael, S. Brackenridge, 2011, Journal of Virology.

Functional Heterogeneity and High Frequencies of Cytomegalovirus-Specific CD8+ T Lymphocytes in Healthy Seropositive Donors

J. Bell, V. Appay, P. Moss, 2000, Journal of Virology.

Structures of Three HIV-1 HLA-B*5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Nonprogression12

Sarah Rowland-Jones, Andrew J. McMichael, Ian M. Overton, 2005, The Journal of Immunology.

P17-28 LB. The antiviral efficacy of HIV-specific CD8+ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate

S. Rowland-Jones, T. Dong, G. Gillespie, 2009, Retrovirology.

High frequency of cytomegalovirus-specific cytotoxic T-effector cells in HLA-A*0201-positive subjects during multiple viral coinfections.

D. Nixon, X. Jin, S. Bonhoeffer, 2000, The Journal of infectious diseases.

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms

S. Rowland-Jones, P. Easterbrook, A. McMichael, 2012, Proceedings of the National Academy of Sciences.

High viral burden in the presence of major HIV‐specific CD8+ T cell expansions: evidence for impaired CTL effector function

Stefan Kostense, D. Baarle, S. Kostense, 2001, European journal of immunology.

CD8+ T cell responses to human immunodeficiency viruses type 2 (HIV‐2) and type 1 (HIV‐1) gag proteins are distinguishable by magnitude and breadth but not cellular phenotype

S. Rowland-Jones, H. Whittle, G. Gillespie, 2005, European journal of immunology.

Comparison between HIV‐ and CMV‐specific T cell responses in long‐term HIV infected donors

V. Appay, L. Papagno, A. King, 2002, Clinical and experimental immunology.

Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers.

D. Fuchs, R. Price, S. Deeks, 2016, AIDS research and human retroviruses.

Characterization of an HLA‐C‐restricted CTL response in chronic HIV infection

S. Rowland-Jones, P. Easterbrook, F. Plummer, 2010, European journal of immunology.

Mature CD8(+) T lymphocyte response to viral infection during fetal life.

S. Rowland-Jones, H. Whittle, V. Appay, 2003, The Journal of clinical investigation.

Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum.

A. Hill, M. Plebanski, M. Pinder, 1999, Immunity.

Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection12

R. Kaul, S. Rowland-Jones, P. Easterbrook, 2006, The Journal of Immunology.

Functional differences between influenza A-specific cytotoxic T lymphocyte clones expressing dominant and subdominant TCR.

L. Borysiewicz, G. Gillespie, P. Moss, 2001, International immunology.

Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects.

D. Nixon, S. M. Donahoe, G. Ogg, 2001, Virology.

Direct Measurement of CD41 and CD81 T-Cell Responses to CMV in HIV-1-Infected Subjects

D. Nixon, S. M. Donahoe, G. Ogg, 2001 .

Induction of Multifunctional Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T Cells Capable of Proliferation in Healthy Subjects by Using a Prime-Boost Regimen of DNA- and Modified Vaccinia Virus Ankara-Vectored Vaccines Expressing HIV-1 Gag Coupled to CD8+ T-Cell Epitopes

Lucy Dorrell, Andrew J. McMichael, Jill Gilmour, 2006, Journal of Virology.

Identification of a novel HLA B*57 restricted cytotoxic T-lymphocyte epitope within HIV-1 rev

S. Rowland-Jones, P. Easterbrook, J. Kimani, 2006, AIDS.

The Antiviral Efficacy of HIV-Specific CD8+ T-Cells to a Conserved Epitope Is Heavily Dependent on the Infecting HIV-1 Isolate

S. Rowland-Jones, A. McMichael, A. Simmons, 2011, PLoS pathogens.

Human Immunodeficiency Virus Type 1- and Cytomegalovirus-Specific Cytotoxic T Lymphocytes Can Persist at High Frequency for Prolonged Periods in the Absence of Circulating Peripheral CD4+ T Cells

D. Nixon, S. M. Donahoe, W. Borkowsky, 2000, Journal of Virology.

HLA-E restricted, HIV-1 suppressing, Gag specific CD8+ T cells offer universal vaccine opportunities

L. Picker, A. McMichael, P. Borrow, 2020, bioRxiv.

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

K. Garcia, A. McMichael, F. Powrie, 2020, eLife.

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

L. Picker, A. McMichael, P. Borrow, 2018, Nature Communications.

Mature CD 8 + T lymphocyte response to viral infection during fetal life

S. Rowland-Jones, H. Whittle, V. Appay, 2018 .

Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia.

P. Moss, H. Reyburn, J. Bell, 1996, Blood.

Clonal populations of T-cells in patients with B-cell malignancies.

P. Moss, G. Gillespie, 1997, Leukemia & lymphoma.

myeloma and paraproteinemia Clonal populations of CD4+ and CD8+ T cells in patients with multiple

P. Moss, H. Reyburn, G. Gillespie, 2011 .

Intracellular trafficking of HLA-E and its regulation

A. McMichael, P. Borrow, S. Brackenridge, 2023, The Journal of experimental medicine.

How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?

R. Kaul, S. Rowland-Jones, V. Appay, 2001, Immunology letters.

Functional Discrepancies in HIV-Specific CD8+ T-Lymphocyte Populations Are Related to Plasma Virus Load

S. Rowland-Jones, H. Günthard, C. Fagard, 2002, Journal of Clinical Immunology.

HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses

A. McMichael, V. Naranbhai, Mathias Viard, 2023, Nature Immunology.

HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation

P. Klenerman, A. McMichael, P. Borrow, 2023, Science Immunology.

Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides

L. Hassman, A. McMichael, D. Chudakov, 2022, Nature.

High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation

A. McMichael, M. Birnbaum, Brooke D. Huisman, 2023, Nature communications.

HIV-1-specific CD8 T cell responses in a pediatric slow progressor infected as a premature neonate.

S. Rowland-Jones, T. Peto, T. Rostron, 2002, AIDS.

Incoming HIV Virion-Derived Gag Spacer Peptide 2 (p1) is a Target of Effective CD8+ T Cell Antiviral Responses

C. Brander, V. Miller, T. Peto, 2020, SSRN Electronic Journal.

Structures of Three HIV-1 HLA-B*5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Nonprogression12

R. Kaul, P. Roche, G. Gillespie, 2005, The Journal of Immunology.

Differentiation of Cytomegalovirus-specific Cd8

Ozdemir, Green, H. Fernandez, 2022 .