K. Neale

发表

A survey of phenotypic features in juvenile polyposis.

S. Hodgson, P. Milla, V. Murday, 1998, Journal of medical genetics.

Features of duodenal cancer in patients with familial adenomatous polyposis.

A. Spigelman, K. Neale, S. Clark, 2009, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations.

O. Sieber, F. Setién, M. Esteller, 2008, Experimental and molecular pathology.

Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.

W. Bodmer, R. Houlston, B. Leggett, 1998, Human molecular genetics.

Screening SMAD1,SMAD2, SMAD3, andSMAD5 for germline mutations in juvenile polyposis syndrome

W. Bodmer, R. Houlston, B. Leggett, 1999, Gut.

Analysis of genetic and phenotypic heterogeneity in juvenile polyposis

W. Bodmer, R. Houlston, B. Leggett, 2000, Gut.

Risk factors predicting intra-abdominal desmoids in familial adenomatous polyposis: a single centre experience

P. Tekkis, K. Neale, S. Clark, 2010, Techniques in Coloproctology.

Desmoid tumours complicating familial adenomatous polyposis

K. Neale, S. Clark, R. Phillips, 1999, The British journal of surgery.

Rectal cancer risk in patients treated for familial adenomatous polyposis

H. Järvinen, S. Bülow, R. Hultcrantz, 1992, The British journal of surgery.

The history of familial adenomatous polyposis

S. Bülow, K. Neale, T. Berk, 2005, Familial Cancer.

Regionally clustered APC mutations are associated with a severe phenotype and occur at a high frequency in new mutation cases of adenomatous polyposis coli.

S. Gayther, D. Wells, J. Delhanty, 1994, Human molecular genetics.

An overview of inherited intestinal polyposis syndromes

K. Neale, V. Cuthill, 2014 .

Peutz-Jeghers Syndrome: Intriguing Suggestion of Gastrointestinal Cancer Prevention From Surveillance

R. Phillips, K. Neale, S. Clark, 2011, Diseases of the colon and rectum.

Further observations on LKB1/STK11 status and cancer risk in Peutz–Jeghers syndrome

R. Houlston, D. Eccles, I. Tomlinson, 2003, British Journal of Cancer.

Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation

I. Tomlinson, P. Bassett, R. Phillips, 2004, Gut.

Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes

R. Houlston, I. Tomlinson, S. Hodgson, 2002, Gut.

Juvenile Polyposis Syndrome: A Study of Genotype, Phenotype, and Long-term Outcome

R. Phillips, K. Neale, S. Clark, 2012, Diseases of the colon and rectum.

Mucosectomy With Handsewn Anastomosis Reduces the Risk of Adenoma Formation in the Anorectal Segment After Restorative Proctocolectomy for Familial Adenomatous Polyposis

P. Tekkis, K. Neale, S. Clark, 2011, Annals of surgery.

Comparison of outcomes of ileal pouch–anal anastomosis for familial adenomatous polyposis with and without previous ileorectal anastomosis

R. Lovegrove, P. Tekkis, K. Neale, 2007, The British journal of surgery.

Attenuated adenomatous polyposis coli

I. Frayling, R. Phillips, K. Neale, 1999, Diseases of the colon and rectum.

Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3.

L. Aaltonen, W. Bodmer, A. de la Chapelle, 1998, Journal of medical genetics.

Pigmented lesions of the retinal pigment epithelium and familial adenomatous polyposis

K. Neale, P. Polkinghorne, G. Schoeppner, 1990, Eye.

Living with a stoma.

R. Phillips, K. Neale, 1988, BMJ.

Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation

O. Sieber, P. Hutter, A. Rowan, 2006, Gut.

FAECAL BILE ACIDS, DYSPLASIA, AND CARCINOMA IN ULCERATIVE COLITIS

J. Lennard-jones, K. Neale, D. Melville, 1987, The Lancet.

The establishment of a polyposis register

S. Bülow, J. Burn, K. Neale, 1993, International Journal of Colorectal Disease.

Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.

W F Bodmer, P Rozen, L. Aaltonen, 2001, American journal of human genetics.

Refining the relation between ‘first hits’ and ‘second hits’ at the APC locus: the ‘loose fit’ model and evidence for differences in somatic mutation spectra among patients

L. Lipton, O. Sieber, I. Tomlinson, 2003, Oncogene.

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

Ian Tomlinson, Andrew Rowan, Susan Clark, 1999, Nature Medicine.

Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome.

K. Lunetta, L. Aaltonen, W. Bodmer, 1997, Cancer research.

Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC

O. Sieber, W. Bodmer, I. Tomlinson, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22.

S. Seal, M. Stratton, N. Rahman, 1999, Gastroenterology.

Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer.

L. Aaltonen, I. Tomlinson, T. Mäkelä, 1999, Human molecular genetics.

Variants at the secretory phospholipase A2 (PLA2G2A) locus: analysis of associations with familial adenomatous polyposis and sporadic colorectal tumours

W. Bodmer, I. Tomlinson, K. Neale, 1996, Annals of human genetics.

Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or “multiple” colorectal adenomas

L. Lipton, O. Sieber, W. Bodmer, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases

I. Tomlinson, M. Churchman, S. Hodgson, 2004, Gut.

A 10‐year review of surgery for desmoid disease associated with familial adenomatous polyposis

R. Phillips, K. Neale, A. Latchford, 2006, The British journal of surgery.

Origins of the Leeds Castle Polyposis Group

K. Neale, Steffen Bülow on Behalf of the Leeds Castle Polyposis Group, 2005, Familial Cancer.

A review of physical abnormalities in familial adenomatous polyposis.

J. Landgrebe, K. Neale, H. Bussey, 1991, Singapore medical journal.

A modifying locus for familial adenomatous polyposis may be present on chromosome 1p35-p36.

W. Bodmer, A. Spigelman, I. Talbot, 1996, Journal of medical genetics.

Pouch adenomas in patients with familial adenomatous polyposis

A. Spigelman, I. Talbot, K. Neale, 1993, The British journal of surgery.

Polyposis syndromes: administrative care

K. Neale, Rebecca Jones, D. Coleman, 2014 .

Overview of Peutz-Jegher's and juvenile polyposis syndromes

K. Neale, Jackie Hawkins, 2014 .

Genetic testing for inherited polyposis syndromes

K. Neale, P. McGinty, 2014 .

Comparison of morbidity and function after colectomy with ileorectal anastomosis or restorative proctocolectomy for familial adenomatous polyposis

K. Neale, H. Bussey, R. Nicholls, 1991, The British journal of surgery.

FAMILIAL POLYPOSIS COLI

J. Delhanty, M. Rees, K. Neale, 1988, The Lancet.

Juvenile polyposis

I. Talbot, S. Hodgson, D. Desai, 1995, The British journal of surgery.

Jejunal cancer in patients with familial adenomatous polyposis.

K. Neale, R. Phillips, A. Sinha, 2010, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.