D. Eccles

发表

Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH

Siân Jones, D. Evans, J. Maynard, 2003, The Lancet.

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

Rodney J Scott, Finlay Macrae, Annika Lindblom, 2011, The Lancet.

RNA analysis reveals splicing mutations and loss of expression defects in MLH1 and BRCA1

A. Sharp, A. Lucassen, G. Pichert, 2004, Human mutation.

Prevalence of adenomas and hyperplastic polyps in mismatch repair mutation carriers among CAPP2 participants: report by the colorectal adenoma/carcinoma prevention programme 2.

D. Bishop, A. Lindblom, G. Evans, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Increased colorectal cancer incidence in obligate carriers of heterozygous mutations in MUTYH.

D. Evans, P. Wark, J. Sampson, 2009, Gastroenterology.

Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.

W. Bodmer, R. Houlston, B. Leggett, 1998, Human molecular genetics.

Screening SMAD1,SMAD2, SMAD3, andSMAD5 for germline mutations in juvenile polyposis syndrome

W. Bodmer, R. Houlston, B. Leggett, 1999, Gut.

Analysis of genetic and phenotypic heterogeneity in juvenile polyposis

W. Bodmer, R. Houlston, B. Leggett, 2000, Gut.

Edinburgh Research Explorer Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer

D. Bishop, R. Scott, A. Lindblom, 2022 .

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

J. R. Wilson, David M. Holden, P. W. Foster, 2016, British Journal of Cancer.

Optimal selection of individuals for BRCA mutation testing.

D. Evans, F. Lalloo, D. Eccles, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Identification of a de novo BRCA1 mutation in a woman with early onset bilateral breast cancer

D. Baralle, D. Eccles, E. Edwards, 2009, Familial Cancer.

Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome.

D. Bishop, R. Scott, D. Evans, 2008, The New England journal of medicine.

implications for chemoprevention BRCA1 mutation and neuronal migration defect

B. Castle, D. Eccles, D. Bunyan, 2006 .

Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer

R. Scott, A. Lindblom, J. Lubiński, 2016 .

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer

David Evans, R. Scott, D. Evans, 2016 .

Primary fibroblasts from BRCA1 heterozygotes display an abnormal G1/S cell cycle checkpoint following UVA irradiation but show normal levels of micronuclei following oxidative stress or mitomycin C treatment.

R. Eeles, T. McMillan, J. Peacock, 2004, International journal of radiation oncology, biology, physics.

Apoptosis, ageing and cancer susceptibility

R. Eeles, A. Ardern-Jones, D. Easton, 2003, British Journal of Cancer.

populationsilent, rare, and paucimorphic mutations in the general , and demonstration of the potential to identify severe, LDLR and BRCA1 Mutation scanning by meltMADGE: Validations using

D. Lawlor, S. Humphries, I. Simpson, 2006 .

Mutation scanning by meltMADGE: validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population.

D. Lawlor, C. Cooper, S. Humphries, 2005, Genome research.

Survival in women with MMR mutations and ovarian cancer: a multicentre study in Lynch syndrome kindreds

P. Møller, G. Evans, H. Järvinen, 2009, Journal of Medical Genetics.

A novel 3′ mutation in the APC gene in a family presenting with a desmoid tumour

A. Bateman, D. Eccles, F. Ross, 2001, Journal of medical genetics.

Hereditary haemochromatosis should be more widely known about

P. Roderick, D. Eccles, W. Rosenberg, 1999, BMJ.

Cancer occurrence during follow-up of the CAPP2 study -aspirin use for up to four years significantly reduces Lynch syndrome cancers for up to several years after completion of therapy

A. Lindblom, G. Evans, J. Mathers, 2010, Hereditary Cancer in Clinical Practice.

The presence of congenital hypertrophy of the retinal pigment epithelium in a subgroup of patients with adenomatous polyposis coli mutations

D. Eccles, D. Bunyan, A. Reck, 1997, Eye.

First case report of Muir–Torre syndrome associated with non-small cell lung cancer

A. Bateman, G. Crawford, C. Ottensmeier, 2009, Familial Cancer.

Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice.

Kimberly Burton, Tsuneo Imai, Yan Song, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome.

K. Lunetta, L. Aaltonen, W. Bodmer, 1997, Cancer research.

Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

D. Bishop, R. Scott, D. Evans, 2020, The Lancet.

A Randomized Placebo-Controlled Prevention Trial of Aspirin and/or Resistant Starch in Young People with Familial Adenomatous Polyposis

D. Bishop, D. Evans, J. Mathers, 2011, Cancer Prevention Research.

Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3

V. Moskvina, R. Houlston, D. Evans, 2008, Gut.

Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Carney Complex, Peutz-Jeghers Syndrome, Cowden Disease, and Bannayan-Zonana Syndrome Share Cutaneous and Endocrine Manifestations, But Not Genetic

I. Tomlinson, C. Basson, C. Eng, 2022 .

Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.

D. Bishop, R. Scott, D. Evans, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Primary Clear Cell Microcystic Adenoma of the Sinonasal Cavity: Pathological or Fortuitous Association?

A. Bateman, R. Cooper, G. Crawford, 2017, Case reports in pathology.

Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD

C. Turnbull, J. Ware, N. Whiffin, 2021, Genetics in medicine : official journal of the American College of Medical Genetics.

Familial Adenomatous Polyposis-Associated Desmoids Display Significantly More Genetic Changes than Sporadic Desmoids

B. Alman, P. Devilee, P. Radice, 2011, PloS one.

Adenomatous polyposis coli and a cytogenetic deletion of chromosome 5 resulting from a maternal intrachromosomal insertion.

J. Barber, J. Delhanty, D. Eccles, 1994, Journal of medical genetics.

Loss of maternal chromosome 11 is a signature event in SDHAF2, SDHD, and VHL-related paragangliomas, but less significant in SDHB-related paragangliomas

E. Jordanova, P. Devilee, E. Korpershoek, 2017, Oncotarget.

BRCA1 mutation and neuronal migration defect: implications for chemoprevention

B. Castle, D. Eccles, D. Bunyan, 2005, Journal of Medical Genetics.

Neuronal migration defect in a BRCA1 gene carrier: possible focal nullisomy?

D. Pilz, D. Eccles, C. Kennedy, 2003, Journal of medical genetics.

Genotype-phenotype correlations of new causative APC gene mutations in patients with familial adenomatous polyposis.

D. Eccles, D. Bunyan, D. Finnis, 1995, Journal of medical genetics.

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

D. Bishop, R. Scott, D. Evans, 2013 .

Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene.

J. Barber, D. Eccles, R. Fodde, 1996, American journal of human genetics.

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study

Katherine M. Tucker, L. Kiemeney, H. Grönberg, 2011, BJU international.

Non-uptake of predictive genetic testing for BRCA1/2 among relatives of known carriers: attributes, cancer worry, and barriers to testing in a multicenter clinical cohort.

S. Ashley, R. Eeles, D. Evans, 2004, Genetic testing.

p53 mutation is a common genetic event in ovarian carcinoma.

H. Kitchener, D. Eccles, N. Haites, 1993, Cancer research.

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

D. Bishop, A. Lindblom, J. Lubiński, 2011 .

A novel 3' mutation in the APC gene in a family presenting with a desmoid tumour.

A. Bateman, D. Eccles, F. Ross, 2001, Journal of medical genetics.

Segregation analysis of ovarian cancer using diathesis to include other cancers

N. Morton, D. Bishop, D. Eccles, 1997, Annals of human genetics.

Polymorphic variation in CYP19 and the risk of breast cancer.

D. Eccles, I. Campbell, S. Baxter, 2001, Carcinogenesis.

A Randomized Placebo-Controlled Prevention Trial of Aspirin and/or Resistant Starch in Young People with Familial Adenomatous Polyposis

D. Bishop, J. Mathers, R. Fodde, 2011, Cancer Prevention Research.

Genotype-phenotype correlations of new causative APC gene mutations in patients with familial adenomatous polyposis.

D. Eccles, D. Bunyan, D. Finnis, 1995, Journal of medical genetics.

DIAGNOSIS AND MANAGEMENT OF HAEMOCHROMATOSIS SINCE THE DISCOVERY OF THE HFE GENE: A EUROPEAN EXPERIENCE

Robson, P. Gasparini, C. Patch, 2000, British journal of haematology.

6000 Aspirin prevents cancer in Lynch syndrome

J. Mathers, J. Mecklin, J. Burn, 2009 .