R. Sekido

发表

Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation

R. Lovell-Badge, A. Cooney, D. Riethmacher, 2009, Cell.

Impairment of T Cell Development in δ EF1 Mutant Mice

H. Kikutani, K. Kawakami, H. Kondoh, 1997, The Journal of experimental medicine.

Identification of SOX3 as an XX male sex reversal gene in mice and humans.

James N. Hughes, A. Sinclair, R. Lovell-Badge, 2011, The Journal of clinical investigation.

Mechanisms of gonadal morphogenesis are not conserved between chick and mouse.

R. Lovell-Badge, R. Sekido, 2007, Developmental biology.

Fgf9 and Wnt4 Act as Antagonistic Signals to Regulate Mammalian Sex Determination

R. Lovell-Badge, J. Brennan, R. Behringer, 2006, PLoS biology.

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

R. Lovell-Badge, R. Sekido, 2008 .

Sex determination and SRY: down to a wink and a nudge?

R. Lovell-Badge, R. Sekido, 2009, Trends in genetics : TIG.

Genetic Control of Testis Development

R. Lovell-Badge, R. Sekido, 2012, Sexual Development.

Failure of SOX9 Regulation in 46XY Disorders of Sex Development with SRY, SOX9 and SF1 Mutations

R. Lovell-Badge, V. Harley, R. Sekido, 2011, PloS one.

The origin of the Mullerian duct in chick and mouse.

R. Lovell-Badge, R. Sekido, S. Guioli, 2007, Developmental biology.

Sex-determining genes in mice: building pathways.

R. Lovell-Badge, R. Sekido, C. Canning, 2002, Novartis Foundation symposium.

Two mechanisms in the action of repressor δEF1: binding site competition with an activator and active repression

H. Kondoh, K. Murai, R. Sekido, 1997, Genes to cells : devoted to molecular & cellular mechanisms.

The 8-Crystallin Enhancer-Binding Protein 6EF1 Is a Repressor of E2-Box-Mediated Gene Activation

Y. Nabeshima, R. Sekido, Y. Kamachi, 2022 .

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

R. Lovell-Badge, R. Sekido, 2008, Nature.

SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.

R. Lovell-Badge, G. Penny, R. Sekido, 2004, Developmental biology.

PRELP Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression

K. Tsumoto, R. Hamamoto, Ken Asada, 2022, Cancers.

Identification of the first promoter‐specific gain‐of‐function SOX9 missense variant (p.E50K) in a patient with 46,XX ovotesticular disorder of sex development

S. Takada, Y. Ogawa, R. Sekido, 2021, American journal of medical genetics. Part A.

Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development.

H. Kondoh, R. Sekido, Y. Kamachi, 2001, Genes & development.

Sex reversal following deletion of a single distal enhancer of Sox9

R. Lovell-Badge, Danielle M Maatouk, R. Sekido, 2018, Science.

Excess DAX1 leads to XY ovotesticular disorder of sex development (DSD) in mice by inhibiting steroidogenic factor-1 (SF1) activation of the testis enhancer of SRY-box-9 (Sox9).

R. Lovell-Badge, D. Wilhelm, V. Harley, 2012, Endocrinology.

Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues

S. Takada, T. Ogata, Y. Matsubara, 2016, Human mutation.

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

R. Lovell-Badge, R. Sekido, 2008, Nature.

The potential role of SRY in epigenetic gene regulation during brain sexual differentiation in mammals.

R. Sekido, 2014, Advances in genetics.

Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination

R. Lovell-Badge, K. Parker, B. Capel, 2007, Proceedings of the National Academy of Sciences.

Organization of the gene encoding transcriptional repressor deltaEF1 and cross-species conservation of its domains.

H. Kondoh, M. Okanami, R. Sekido, 1996, Gene.

Delta-crystallin enhancer binding protein delta EF1 is a zinc finger-homeodomain protein implicated in postgastrulation embryogenesis.

H. Kondoh, H. Kondoh, K. Murai, 1993, Development.

Identification of SOX 3 as an XX male sex reversal gene in mice and humans

James N. Hughes, A. Sinclair, R. Lovell-Badge, 2010 .

A MicroRNA (mmu-miR-124) Prevents Sox9 Expression in Developing Mouse Ovarian Cells1

R. Lovell-Badge, D. G. Lupiáñez, R. Sekido, 2013, Biology of reproduction.

Summary sentence: In vitro knock-down experiments show that miR-124 is responsible for SOX9 down-regulation in developing ovarian cells Keywords: microRNA, microarray, miR-124, sex determination, gonad development, ovary, cell transfection, gene expression, regulation of translation.

R. Lovell-Badge, D. G. Lupiáñez, R. Sekido, 2013 .

Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells

K. Docherty, R. Sekido, N. Owen, 2021, Communications Biology.

The delta-crystallin enhancer-binding protein delta EF1 is a repressor of E2-box-mediated gene activation

Y. Nabeshima, H. Kondoh, K. Murai, 1994, Molecular and cellular biology.

SRY: A transcriptional activator of mammalian testis determination.

R. Sekido, 2010, The international journal of biochemistry & cell biology.

Sox9 gene regulation and the loss of the XY/XX sex-determining mechanism in the mole vole Ellobius lutescens

R. Lovell-Badge, V. Harley, R. Sekido, 2012, Chromosome Research.

The role of the proteoglycans OMD and PRELP in the maintenance of brain vasculature

N. Sasai, R. Sekido, H. Davaapil, 2018 .

Impairment of T Cell Development in ␦ Ef1 Mutant Mice

R. Sekido, Y. Higashi, H. Moribe, 1997 .

Excess DAX1 leads to XY ovotesticular disorder of sex development (DSD) in mice by inhibiting steroidogenic factor-1 (SF1) activation of the testis enhancer of SRY-box-9 (Sox9).

R. Lovell-Badge, D. Wilhelm, V. Harley, 2012, Endocrinology.