D. Shepherd

发表

Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells.

R. Strausberg, L. Olsen, V. Cerundolo, 2016, Cancer research.

Some lessons from the systematic production and structural analysis of soluble (alpha)(beta) T-cell receptors.

S. Sainsbury, R. Owens, D. Stuart, 2009, Journal of immunological methods.

Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation

P. Cresswell, G. Besra, V. Cerundolo, 2013, Proceedings of the National Academy of Sciences.

Structure of human CD1b with bound ligands at 2.3 Å, a maze for alkyl chains

Gerd Ritter, Richard R. Schmidt, Dawn Shepherd, 2002, Nature Immunology.

The crystal structure of human CD1d with and without α-galactosylceramide

A. Fersht, G. Besra, V. Cerundolo, 2005, Nature Immunology.

glycolipid-specific T cells

E. Jones, A. Karadimitris, N. Dulphy, 2003 .

Generation of CD1 tetramers as a tool to monitor glycolipid-specific T cells.

V. Cerundolo, E. Jones, A. Karadimitris, 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Cutting Edge: Nonglycosidic CD1d Lipid Ligands Activate Human and Murine Invariant NKT Cells1

G. Besra, V. Cerundolo, James Brown, 2008, The Journal of Immunology.

Dendritic Cell Function Can Be Modulated through Cooperative Actions of TLR Ligands and Invariant NKT Cells1

V. Cerundolo, I. Hermans, M. Salio, 2007, The Journal of Immunology.

A Shift in the Phenotype of Melan-A-Specific CTL Identifies Melanoma Patients with an Active Tumor-Specific Immune Response1

A. Harris, F. Sallusto, A. Lanzavecchia, 2000, The Journal of Immunology.

Structure and binding kinetics of three different human CD1d–α-galactosylceramide–specific T cell receptors

D. Stuart, B. Jakobsen, V. Cerundolo, 2006, The Journal of experimental medicine.

Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence

A. Harris, V. Cerundolo, P. Coulie, 2005, International journal of cancer.

University of Birmingham The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells

G. Besra, J. A. Torreño-Pina, M. Garcia-Parajo, 2016 .

The Processed Amino-Terminal Fragment of Human TLR7 Acts as a Chaperone To Direct Human TLR7 into Endosomes

V. Cerundolo, C. Reis e Sousa, D. Shepherd, 2015, The Journal of Immunology.

Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes.

N. Seidah, V. Cerundolo, B. Kessler, 2013, Immunity.

Mature Dendritic Cells Prime Functionally Superior Melan-A-Specific CD8+ Lymphocytes as Compared with Nonprofessional APC1

V. Cerundolo, M. Salio, P. Dunbar, 2001, The Journal of Immunology.

Nonprofessional APC Lymphocytes as Compared with + Superior MelanA-Specific CD 8 Mature Dendritic Cells Prime Functionally

V. Cerundolo, M. Salio, P. Dunbar, 2001 .

of three diff erent human CD1d-α- galactosylceramide-specifi c T cell receptors

D. Stuart, B. Jakobsen, V. Cerundolo, 2006 .

Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice.

M. Smyth, D. Godfrey, A. Baxter, 2001, International immunology.

Essential role for autophagy during invariant NKT cell development

G. Besra, V. Cerundolo, A. Simon, 2014, Proceedings of the National Academy of Sciences.

This information is current as Human TLR 7 into Endosomes DirectHuman TLR 7 Acts as a Chaperone To The Processed Amino-Terminal Fragment of Waithe

C. Sousa, D. Shepherd, D. Waithe, 2015 .

Active Tumor-Specific Immune Response CTL Identifies Melanoma Patients with an A Shift in the Phenotype of Melan-A-Specific

A. Harris, F. Sallusto, V. Cerundolo, 2000 .

Expression of MHC Class I–Related Chain B (MICB) Molecules on Renal Transplant Biopsies

S. Fuggle, V. Cerundolo, M. Salio, 2006, Transplantation.

High Frequency of Cytolytic 21-Hydroxylase–Specific CD8+ T Cells in Autoimmune Addison’s Disease Patients

K. Badenhoop, V. Cerundolo, S. Pearce, 2014, Journal of Immunology.

Diverse Endogenous Antigens for Mouse NKT Cells: Self-Antigens That Are Not Glycosphingolipids

Anneliese O. Speak, A. Speak, V. Cerundolo, 2011, The Journal of Immunology.

GlycosphingolipidsNKT Cells: Self-Antigens That Are Not Diverse Endogenous Antigens for Mouse

V. Cerundolo, F. Platt, Kronenberg, 2010 .

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy.

A. Harris, V. Cerundolo, I. Stratford, 2004, The Journal of clinical investigation.

Defective iron homeostasis and hematological abnormalities in Niemann-Pick disease type C1

F. Platt, F. Porter, A. Abdul-Sada, 2022, Wellcome open research.

and Invariant NKT Cells Ligands through Cooperative Actions of TLR Dendritic Cell Function Can Be Modulated

V. Cerundolo, I. Hermans, M. Salio, 2013 .

Inhibition of the Niemann-Pick C1 protein is a conserved feature of multiple strains of pathogenic mycobacteria

G. Larrouy-Maumus, F. Platt, B. Robertson, 2022, Nature Communications.

Regulation of natural killer cell activity by anti-I-region monoclonal antibodies.

J. Remington, S. Sharma, D. Shepherd, 1984, Cellular immunology.

Amide Analogues of CD1d Agonists Modulate iNKT-Cell-Mediated Cytokine Production

G. Besra, V. Cerundolo, H. Ghadbane, 2012, ACS chemical biology.

Phage display‐derived recombinant antibodies with TCR‐like specificity against α‐galactosylceramide and its analogues in complex with human CD1d molecules

G. Besra, V. Cerundolo, P. Dellabona, 2008, European journal of immunology.

Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants

V. Cerundolo, M. Salio, J. Silk, 2009, ChemMedChem.

Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann‐Pick disease type C

Anneliese O. Speak, A. Speak, G. Besra, 2012, European journal of immunology.

Molecular basis for a new bovine model of Niemann-Pick type C disease

Benjamin T. Porebski, B. T. Porebski, D. Priestman, 2020, PloS one.

Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection

Tao Dong, Nathalie Rufer, Susan Little, 2004, PLoS biology.

Combined functional and kinetic measurements to address the role of saposins in loading CD1d molecules with iNKT cell agonists

P. Cresswell, G. Besra, M. Salio, 2012 .

The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

G. Besra, V. Cerundolo, E. Jones, 2007, The Journal of experimental medicine.

Non‐glycosidic compounds can stimulate both human and mouse iNKT cells

G. Besra, V. Cerundolo, H. Ghadbane, 2016, European journal of immunology.

The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid

A. Fersht, G. Besra, V. Cerundolo, 2004 .

Unbiased yeast screens identify cellular pathways affected in Niemann–Pick disease type C

M. Schuldiner, F. Platt, S. Chuartzman, 2020, Life Science Alliance.

Modulation of human natural killer T cell ligands on TLR-mediated antigen-presenting cell activation

Anneliese O. Speak, A. Speak, G. Besra, 2007, Proceedings of the National Academy of Sciences.

MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A

G. Besra, E. Newell, K. Teng, 2018, Nature Communications.

Diverse Streptococcus pneumoniae Strains Drive a Mucosal-Associated Invariant T-Cell Response Through Major Histocompatibility Complex class I–Related Molecule–Dependent and Cytokine-Driven Pathways

Andries J. van Tonder, P. Klenerman, V. Cerundolo, 2017, The Journal of infectious diseases.

Diverse Streptococcus pneumoniae strains drive a MAIT cell response through MR1-dependent and cytokine-driven pathways

Andries J. van Tonder, P. Klenerman, V. Cerundolo, 2017, bioRxiv.

Release of acidic store calcium is required for effective priming of the NLRP3 inflammasome

A. Galione, G. Churchill, F. Platt, 2022, bioRxiv.

Generation and characterization of HLA-A2 transgenic mice expressing the human TCR 1G4 specific for the HLA-A2 restricted NY-ESO-1157-165 tumor-specific peptide

J. Yewdell, V. Cerundolo, Gennaro Prota, 2021, Journal for ImmunoTherapy of Cancer.

Plasmacytoid dendritic cells prime IFN‐γ‐secreting melanoma‐specific CD8 lymphocytes and are found in primary melanoma lesions

V. Cerundolo, M. Colonna, M. Cella, 2003, European journal of immunology.

The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid12

Alan R. Fersht, Dawn Shepherd, Nathan R. Zaccai, 2003, The Journal of Immunology.

Bound Bacterial Glycolipid The Crystal Structure of Human CD 1 b with a

A. Fersht, G. Besra, V. Cerundolo, 2004 .

Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection.

Yuetsu Tanaka, Dawn Shepherd, Vincenzo Cerundolo, 2006, Blood.

Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1–Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor

S. Hutchinson, A. Sewell, A. Galione, 2010, The Journal of Immunology.

Coreceptor TCR and by the Use of the CD 8 Cells Is Modulated by the Affinity of Reticulum of NY-ESO-1 Specific T Release from the Endoplasmic 2 + Ca

Linda, S. Hutchinson, A. Sewell, 2010 .

The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells

G. Besra, M. Garcia-Parajo, C. Manzo, 2016, Proceedings of the National Academy of Sciences.

Lipid mediated inhibition of Niemann-Pick C1 protein is an evolutionary conserved feature of multiple Mycobacterium lineages and non-tubercular mycobacteria

G. Larrouy-Maumus, F. Platt, B. Robertson, 2021 .

Binding Strength and Dynamics of Invariant Natural Killer Cell T Cell Receptor/CD1d-Glycosphingolipid Interaction on Living Cells by Single Molecule Force Spectroscopy*

V. Cerundolo, R. Zhu, P. Hinterdorfer, 2011, The Journal of Biological Chemistry.

The crystal structure of human CD1d with and without alpha-galactosylceramide.

Gerd Ritter, Michael Koch, Dawn Shepherd, 2005, Nature immunology.

Leukocytes and mediators in bronchoalveolar lavage during allergen-induced late-phase asthmatic reactions.

S. Durham, A. Kay, G. Gleich, 1989, The American review of respiratory disease.

Grafting of Cyclodextrin to Theranostic Nanoparticles Improves Blood-Brain Barrier Model Crossing

E. Reimhult, A. Puglisi, D. Shepherd, 2023, Biomolecules.

Structure and binding kinetics of three different human CD1d–α-galactosylceramide–specific T cell receptors

K. Harlos, D. Shepherd, N. Lissin, 2006, The Journal of experimental medicine.