A. Cohen

发表

PURINE NUCLEOTIDE METABOLISM IN HUMAN NEUROBLASTOMA CELL LINES: 99

H. Yeger, C. Kaplinsky, J. Barankiewicz, 1985, Pediatric Research.

Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency.

D. Martin, A. Cohen, S. Polmar, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Establishment and characterization of adenosine deaminase-deficient human T cell lines.

W. Anderson, H. Mitsuya, D. Kohn, 1989, Journal of immunology.

Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies

A. Cohen, C. Roifman, E. Grunebaum, 2013, Current opinion in allergy and clinical immunology.

Autocrine and paracrine growth control by granulocyte-monocyte colony-stimulating factor of acute lymphoblastic leukemia cells.

Paulo N. Correa, M. Freedman, I. Dubé, 1993, Blood.

Autocrine and paracrine growth control by granulocyte-monocyte colony-stimulating factor of acute lymphoblastic leukemia cells

Paulo N. Correa, M. Freedman, I. Dubé, 1993 .

CD8/CD4 lineage commitment occurs by an instructional/default process followed by positive selection

A. Cohen, P. Benveniste, G. Knowles, 1996, European journal of immunology.

Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

David W. Martin, L. Gudas, A. Cohen, 1978, Cell.

Purine nucleotide metabolism in phytohemagglutinin-induced human T lymphocytes.

J. Barankiewicz, A. Cohen, 1987, Archives of biochemistry and biophysics.

Phorbol esters and CAMP differentially regulate the expression of CD4 and CD8 in human thymocytes

H. Martinez-Valdez, V. Madrid-Marina, A. Cohen, 2002, BMC Immunology.

Deoxyguanosine toxicity in a mouse T lymphoma: Relationship to purine nucleoside phosphorylase-associated immune dysfunction

David W. Martin, L. Gudas, A. Cohen, 1978, Cell.

Selective toxicity of deoxyguanosine and arabinosyl guanine for T-leukemic cells.

E. Gelfand, A. Cohen, J. W. Lee, 1983, Blood.

The expression of c-fos, c-jun, and c-myc genes is regulated by heat shock in human lymphoid cells.

M. Freedman, H. Martinez-Valdez, A. Cohen, 1990, Journal of immunology.

Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic disease

D. Martin, A. Cohen, B. Ullman, 1976, Cell.

Materials and Methods Brief Definitive Report Depletion of Cd8+ Cells in Human Thymic Medulla Results in Selective Immune Deficiency

P. Thorner, A. Cohen, C. Roifman, 2022 .

Two novel mutations in a purine nucleoside phosphorylase (PNP)‐deficient patient

A. Cohen, C. Roifman, I. Dalal, 2001, Clinical genetics.

Identification of an ionomycin/cyclosporin A‐responsive element within the human T cell receptor gamma enhancer

T. Hettmann, A. Cohen, 1995, European journal of immunology.

Deferoxamine: a reversible S-phase inhibitor of human lymphocyte proliferation

E. Gelfand, M. Freedman, H. Lederman, 1984 .

In vitro and in vivo effects of deferoxamine in neonatal acute leukemia

Z. Estrov, E. Gelfand, M. Freedman, 1987 .

Extracellular ATP Metabolism in B and T Lymphocytes

A. Cohen, J. Barankiewicz, 1990, Annals of the New York Academy of Sciences.

Absence of lymphocyte ecto-5'-nucleotidase in infants with reticuloendotheliosis and eosinophilia (Omenn's syndrome).

E. Gelfand, A. Cohen, C. P. Rao, 1984, Blood.

Absence of lymphocyte ecto-5'-nucleotidase in infants with reticuloendotheliosis and immunodeficiency.

N. Sigal, E. Gelfand, A. Cohen, 1984, Advances in experimental medicine and biology.

Abnormal purine metabolism and purine overproduction in a patient deficient in purine nucleoside phosphorylase.

D. Martin, A. Ammann, A. Cohen, 1976, The New England journal of medicine.

Central role of tumour necrosis factor, GM‐CSF, and interleukin 1 in the pathogenesis of juvenile chronic myelogenous leukaemia

Z. Estrov, M. Freedman, A. Cohen, 1992, British journal of haematology.

Analysis of adenosine-mediated pyrimidine starvation using cultured wild-type and mutant mouse T-lymphoma cells

D. Martin, L. Gudas, A. Cohen, 1978, Somatic cell genetics.

In vitro cytotoxicity of deferoxamine on human marrow haematopoietic progenitors.

Z. Estrov, M. Freedman, E. Gelfand, 1988, Toxicology in vitro : an international journal published in association with BIBRA.

IMMUNODEFICIENCY CAUSED BY PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY

A. Cohen, C. Roifman, E. Grunebaum, 2000, Radiologic Clinics of North America.

Modification of ribonucleotide and deoxyribonucleotide metabolism in interferon-treated human B-lymphoblastoid cells.

C. Kaplinsky, J. Barankiewicz, A. Cohen, 1986, Journal of Interferon Research.

Role of adenosine deaminase and dATP levels in thymocyte apoptosis.

W. Zhu, A. Cohen, P. Benveniste, 1998, Advances in experimental medicine and biology.

p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.

A. Cohen, P. Benveniste, Patricia Benveniste, 1995, Proceedings of the National Academy of Sciences of the United States of America.

B-lineage lymphoid blast crisis in juvenile chronic myelogenous leukemia: II. Interleukin-1-mediated autocrine growth regulation of the lymphoblasts.

Z. Estrov, M. Freedman, A. Cohen, 1995, Leukemia.

Role of intracellular dTTP levels in fluorodeoxyuridine toxicity.

A. Cohen, B. Ullman, 1984, Biochemical pharmacology.

Adenosine Deaminase and Thymocyte Maturation

P. Thorner, J. Mulloy, A. Cohen, 1991, Scandinavian journal of immunology.

Selective toxicity of deoxyguanosine and arabinosyl guanine for T-leukemic cells.

E. Gelfand, A. Cohen, J. W. Lee, 1983, Blood.

Deoxyguanosine triphosphate as a possible toxic metabolite in the immunodeficiency associated with purine nucleoside phosphorylase deficiency.

D. Martin, A. Ammann, L. Gudas, 1978, The Journal of clinical investigation.

Interleukin 6 induces myeloid differentiation of a human biphenotypic leukemic cell line.

M. Freedman, A. Cohen, T. Grunberger, 1992, Leukemia research.

The effect of hydrocortisone on exportable enzyme accumulation in the differentiating chick pancreas.

H. Heller, R. G. Kulka, A. Cohen, 1972, Developmental biology.

In vitro and in vivo effects of deferoxamine in neonatal acute leukemia.

X. H. Wang, Z. Estrov, E. Gelfand, 1987, Blood.

Deferoxamine: a reversible S-phase inhibitor of human lymphocyte proliferation.

M. Freedman, E. Gelfand, H. Lederman, 1984, Blood.

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

A. Levitzki, M. Freedman, A. Gazit, 1996, Nature.

Coordinate regulation of mRNAs encoding adenosine deaminase, purine nucleoside phosphorylase, and terminal deoxynucleotidyltransferase by phorbol esters in human thymocytes.

A. Cohen, H. MARTINEZ‐VALDEZ, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of a mutant mouse lymphoma cell with deficient transport of purine and pyrimidine nucleosides.

D. Martin, A. Cohen, B. Ullman, 1979, The Journal of biological chemistry.

Characterization of mouse lymphoma cells with altered nucleoside transport

A. Cohen, E. Thompson, Changyee Leung, 1985, Journal of cellular physiology.

Selective protection of tubercidin toxicity by nitrobenzyl thioinosine in normal tissues but not in human neuroblastoma cells

Z. Estrov, M. Freedman, H. Yeger, 1986, Cancer Chemotherapy and Pharmacology.

Phorbol esters induce changes in adenosine deaminase, purine nucleoside phosphorylase, and terminal deoxynucleotidyl transferase messenger RNA levels in human leukemic cell lines.

V. Madrid-Marina, A. Cohen, H. MARTINEZ‐VALDEZ, 1990, Cancer research.

Relationship between extracellular and intracellular nucleotide metabolism in human lymphocytes.

H. Dosch, A. Cohen, R. Cheung, 1989 .

Analysis of the drug synergism between thymidine and arabinosyl cytosine using mouse S49 T lymphoma mutants

A. Cohen, B. Ullman, 2004, Cancer Chemotherapy and Pharmacology.

DNA repair in nondividing human lymphocytes: inhibition by deoxyadenosine.

A. Cohen, E. Thompson, 1986, Cancer research.

Association of a lymphocyte purine enzyme deficiency (5'-nucleotidase) with combined immunodeficiency.

H. Dosch, E. Gelfand, A. Cohen, 1980, Clinical immunology and immunopathology.

Mutations in the RNA component of RNase mitochondrial RNA processing might cause Omenn syndrome.

Yiping Gu, A. Cohen, C. Roifman, 2006, The Journal of allergy and clinical immunology.

Differential Response of Embryonic Chick Pancreas Enzymes to Glucocorticoids

H. Heller, R. Zelikson, R. G. Kulka, 1980 .

Mitochondrial Basis for Immune Deficiency: Evidence from Purine Nucleoside Phosphorylase–Deficient Mice

Pier Paolo Pandolfi, P. Pandolfi, M. Hershfield, 2000 .

Mitochondrial Basis for Immune Deficiency

Pier Paolo Pandolfi, Michael Hershfield, P. Pandolfi, 2000, The Journal of experimental medicine.

Nucleotide metabolism in cultured T cells and in cells of patients deficient in adenosine deaminase and purine nucleoside phosphorylase.

D. Martin, L. Gudas, A. Cohen, 1978, Ciba Foundation symposium.

Induction of chymotrypsinogen by hydrocortisone in embryonic chick pancreas in vitro.

R. G. Kulka, A. Cohen, 1974, The Journal of biological chemistry.

Metabolic consequences of DNA damage: alteration in purine metabolism following poly(ADP ribosyl)ation in human T-lymphoblasts.

J. Barankiewicz, A. Cohen, 1987, Archives of biochemistry and biophysics.

Effects of purine nucleoside phosphorylase deficiency on thymocyte development.

C. Ackerley, A. Cohen, C. Roifman, 2011, The Journal of allergy and clinical immunology.

Sensitivity of T-leukemic cells to deoxyguanosine and arabinosyl guanine.

E. Gelfand, A. Cohen, J. W. Lee, 1984, Advances in experimental medicine and biology.

Effect of IGF‐1 on the balance between autophagy of dysfunctional mitochondria and apoptosis

Yiping Gu, A. Cohen, Chunjie Wang, 2004, FEBS letters.

Expression of the human T cell receptor Vβ repertoire

S. Ho, S. Kamel‐Reid, A. Cohen, 1991 .

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking Zap-70 kinase

A. Cohen, H. Dadi, M. Shahar, 1994, Cell.

Identification of a T cell-specific transcriptional enhancer 3' of the human T cell receptor gamma locus.

T. Hettmann, A. Cohen, 1994, Molecular immunology.

Constitutive expression and role in growth regulation of interleukin-1 and multiple cytokine receptors in a biphenotypic leukemic cell line.

M. Freedman, M. Letarte, I. Dubé, 1991, Blood.

Inhibition of suppressor T-cell development following deoxyguanosine administration

E. Gelfand, H. Dosch, A. Cohen, 1980, Nature.

Evidence for distinct catabolic pathways of adenine ribonucleotides and deoxyribonucleotides in human T lymphoblastoid cells.

J. Barankiewicz, A. Cohen, 1984, The Journal of biological chemistry.

Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism.

E. Gelfand, H. Lederman, J. Barankiewicz, 1983, The Journal of biological chemistry.

Relationship of steroid structure to induction of chymotrypsinogen in embryonic chick pancreas in vitro.

R. G. Kulka, A. Cohen, 1975, Endocrinology.

Purine nucleotide metabolism in resident and activated rat macrophages in vitro

A. Cohen, J. Barankiewicz, 1985, European journal of immunology.

Effect of deferoxamine on DNA synthesis, DNA repair, cell proliferation, and differentiation of HL-60 cells.

Z. Estrov, E. Gelfand, M. Freedman, 1987, Leukemia.

The expression of deoxyguanosine toxicity in T lymphocytes at different stages of maturation.

H. Dosch, E. Gelfand, A. Cohen, 1980, Journal of immunology.

Expansion of CD3+ CD4− CD8− T cell population expressing high levels of IL‐5 in Omenn's syndrome

A. Cohen, I. Melamed, C. Roifman, 1994, Clinical and experimental immunology.

Orotic aciduria in two unrelated patients with inherited deficiencies of purine nucleoside phosphorylase.

D. Martin, A. Ammann, A. Cohen, 1977, The Journal of clinical investigation.

Interference with thymocyte differentiation by an inhibitor of S-adenosylhomocysteine hydrolase.

W. Zhu, A. Cohen, Weimin Zhu, 1995, Journal of immunology.

Induction of ecto-5'-nucleotidase activity in human thymocytes.

E. Gelfand, H. Dosch, A. Cohen, 1981, Clinical immunology and immunopathology.

Coordinate transcriptional regulation of alpha and delta chains of the T-cell antigen receptors by phorbol esters and cyclic adenosine 5'-monophosphate in human thymocytes.

H. Martinez-Valdez, A. Cohen, H. MARTINEZ‐VALDEZ, 1988, The Journal of biological chemistry.

Extracellular nucleotide catabolism in human B and T lymphocytes. The source of adenosine production.

H. Dosch, J. Barankiewicz, A. Cohen, 1988, The Journal of biological chemistry.

Role of MHC Class I in Immune Surveillance of Mitochondrial DNA Integrity1

Yiping Gu, A. Cohen, C. Roifman, 2003, The Journal of Immunology.

Ethanol induced nucleotide catabolism in mouse T lymphoblastoid cells in vitro.

J. Barankiewicz, A. Cohen, 1986, Advances in experimental medicine and biology.

Nucleotide catabolism and nucleoside cycles in human thymocytes. Role of orthophosphate.

J. Barankiewicz, A. Cohen, 1984, The Biochemical journal.

Abnormal regulation of de novo purine synthesis and purine salvage in a cultured mouse T‐cell lymphoma mutant partially deficient in adenylosuccinate synthetase

D. Martin, L. Gudas, A. Cohen, 1979, Journal of cellular physiology.

Embryonic and Adult Chymotrypsinogens of Chicken Pancreas

R. G. Kulka, A. Cohen, R. G. KULKA, 1973, Nature.

Phorbol esters and calcium ionophores differentially regulate the transcription of gamma-T-cell antigen receptor gene in human thymocytes.

H. Martinez-Valdez, A. Cohen, H. MARTINEZ‐VALDEZ, 1988, The Journal of biological chemistry.

Synergistic Antiproliferative Effects on HL‐60 Cells: Deferoxamine Enhances Cytosine Arabinoside, Methotrexate, and Daunorubicin Cytotoxicity

Z. Estrov, E. Gelfand, M. Freedman, 1988, The American journal of pediatric hematology/oncology.

Impairment of nucleotide metabolism by iron-chelating deferoxamine.

J. Barankiewicz, A. Cohen, 1987, Biochemical Pharmacology.

ATP-induced activation of human B lymphocytes via P2-purinoceptors.

A. Cohen, C. Roifman, S. Padeh, 1991, Journal of immunology.

Purine metabolism in human T lymphocytes: role of the purine nucleoside cycle.

E. Gelfand, H. Lederman, J. Barankiewicz, 1984, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.

Roles of Alternative Synthetic and Catabolic Purine Pathways in T Lymphocyte Differentiation a

E. Gelfand, A. Cohen, J. Barankiewicz, 1985, Annals of the New York Academy of Sciences.

Functional characterization of human thymocyte subpopulations separated by density gradient centrifugation.

E. Gelfand, H. Lederman, A. Cohen, 1984, Clinical and experimental immunology.

The human T cell receptor gamma genes are transcribed from TATA-less promoters containing a conserved heptamer sequence.

T. Hettmann, A. Cohen, P. Doherty, 1992, Molecular immunology.

Single Cell RNA Sequencing in Patients Enrolled in a Selinexor Clinical Trial Reveals Overexpression of Alternative Nuclear Export Pathways Associated with Resistance to Selinexor in Refractory Multiple Myeloma

I. Amit, A. Weiner, M. Leiba, 2021, Blood.

Purine metabolism in rat macrophages.

J. Barankiewicz, A. Cohen, 1984, Advances in experimental medicine and biology.

Differential regulation of γ and δ T cell antigen receptor gene expression by phorbol esters and Ca2+ ionophores in the acute lymphocyte leukemia DND41 cell line

M. Minden, H. Martinez-Valdez, A. Cohen, 1991 .

Effect of purine nucleosides on rat macrophage function.

A. Cohen, 1984, Advances in experimental medicine and biology.

Purine ribonucleotide and deoxyribonucleotide catabolism in lymphocytes.

J. Barankiewicz, A. Cohen, 1986, Advances in experimental medicine and biology.

Guanosine triphosphate catabolism in purine nucleoside phosphorylase deficient human B lymphoblastoid cells

L. Stein, J. Barankiewicz, A. Cohen, 1984, FEBS letters.

8 RELATIONSHIP BETWEEN EXTRACELLULAR AND INTRACELLULAR NUCLEOTIDE METABOLISM IN HUMAN LYMPHOCYTES

H. Dosch, A. Cohen, R. Cheung, 1988, Pediatric Research.

Differential expression of ecto-nucleotide metabolic enzymes during immunoglobulin gene rearrangements in human pre-B-cells.

H. Dosch, J. Barankiewicz, A. Cohen, 1989, Advances in Experimental Medicine and Biology.

The effect of interferon on cells deficient in nucleoside transport or lacking thymidine kinase activity.

B. Williams, D. Gewert, A. Cohen, 1984, Biochemical and biophysical research communications.

Alteration of ribonucleotide and deoxyribonucleotide metabolism by interferon in human B-lymphoblastoid cells.

C. Kaplinsky, A. Cohen, J. Barankiewicz, 1986 .

Inosine uptake by cultured fibroblasts from normal and purine nucleoside phosphorylase-deficient humans.

D. Martin, A. Cohen, 1977, The Journal of biological chemistry.