P. Kakadia

发表

Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.

C. Print, S. Bohlander, N. Senzer, 2018, JCI insight.

Functional CRISPR and shRNA Screens Identify Involvement of Mitochondrial Electron Transport in the Activation of Evofosfamide

C. Print, S. Bohlander, T. Ketela, 2019, Molecular Pharmacology.

An ETV6-ABL1 fusion in a patient with chronic myeloproliferative neoplasm: Initial response to Imatinib followed by rapid transformation into ALL

S. Bohlander, K. Spiekermann, R. Schmidmaier, 2016, Leukemia Research Reports.

Combined molecular and clinical prognostic index for relapse and survival in cytogenetically normal acute myeloid leukemia.

Guido Marcucci, Christian Buske, Michael Unterhalt, 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

W. Hiddemann, S. Bohlander, H. Blum, 2012, Blood.

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.

W. Hiddemann, S. Bohlander, C. Buske, 2006, Cancer cell.

Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22‐23 in chronic lymphocytic leukemia—unexpected expression pattern of the RHO GTPase activator ARHGAP20

W. Hiddemann, S. Bohlander, C. Buske, 2011, Genes, chromosomes & cancer.

Single cell genotyping of matched bone marrow and peripheral blood cells in treatment naive and AZA-treated MDS and CMML

Alba Rodriguez-Meira, A. Mead, S. Bohlander, 2022, bioRxiv.

Mutations in SEC24D, encoding a component of the COPII machinery, cause a syndromic form of osteogenesis imperfecta.

S. Bohlander, K. Kagan, Filippo Beleggia, 2015, American journal of human genetics.

High Frequency of GATA2 Mutations in Cytogenetically Normal Acute Myeloid Leukemia with Biallelic CEBPA Mutations Identified by Exome Sequencing

W. Hiddemann, S. Bohlander, H. Blum, 2011 .

Aplastic anemia and Klinefelter syndrome.

S. Bhatt, P. Kakadia, S. Shukla, 2004, Cancer genetics and cytogenetics.

Loss of sex chromosome in acute myeloid leukemia

S. Bhatt, P. Kakadia, S. Shukla, 2004 .

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis.

Ulrich Mansmann, Sebastian Vosberg, Wolfgang Hiddemann, 2014, Blood.

Rapid and sensitive screening for CEBPA mutations in acute myeloid leukaemia

W. Hiddemann, S. Bohlander, K. Spiekermann, 2008, British journal of haematology.

DNA Repair and Chromosomal Translocations.

S. Bohlander, P. Kakadia, 2015, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Unexpected variation in leukemia stem cell frequency and genetic heterogeneity in two murine leukemia models initiated by AML1/ETO9a and CALM/AF10

S. Bohlander, P. Browett, M. Chopra, 2019, Leukemia.

Development of capability for genome-scale CRISPR-Cas9 knockout screens in New Zealand

C. Print, S. Bohlander, W. Wilson, 2018 .

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.

S. Bohlander, C. Buske, Guoliang Xu, 2009, Blood.

Characterization of a familial small supernumerary marker chromosome in a patient with adult-onset tongue cancer

B. Dave, P. Kakadia, S. Bakshi, 2008, Cytogenetic and Genome Research.

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM / AF 10-positive leukemia

W. Hiddemann, S. Bohlander, C. Buske, 2022 .

Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients

E. Hoster, W. Hiddemann, S. Bohlander, 2012, Annals of Hematology.

RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes

Wolfgang Hiddemann, Tobias Herold, Karsten Spiekermann, 2012, Haematologica.

GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.

E. Hoster, W. Hiddemann, S. Bohlander, 2012, Blood.

Running title : GATA 2 mutations in bi CEBPA AML 1 GATA 2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia *

E. Hoster, W. Hiddemann, S. Bohlander, 2012 .

The FLT3ITD mRNA level has a high prognostic impact in NPM1 mutated, but not in NPM1 unmutated, AML with a normal karyotype.

E. Hoster, W. Hiddemann, S. Bohlander, 2012, Blood.

Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations

S. Bohlander, M. Askarian-Amiri, B. Baguley, 2018, Front. Oncol..

Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients.

W. Hiddemann, R. Yeh, S. Bohlander, 2013, Blood.

Inactivation of TP 53 correlates with disease progression and low miR-34 a expression in previously treated chronic lymphocytic leukemia patients

W. Hiddemann, R. Yeh, S. Bohlander, 2013 .

Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML)

E. Hoster, W. Hiddemann, S. Bohlander, 2011, Annals of Hematology.

High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature

W. Hiddemann, K. Metzeler, S. Bohlander, 2013, Leukemia & lymphoma.

An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia

Anne-Laure Boulesteix, Ulrich Mansmann, Klaus H. Metzeler, 2011, Leukemia.

Original Communication Loss of sex chromosome in acute myeloid leukemia

S. Bhatt, P. Kakadia, S. Shukla, 2004 .

Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1

S. Bohlander, D. Wojcik, P. Browett, 2019, Blood Cancer Journal.

Analysis of Cooperating Genetic Events in MLLT3-MLL Rearranged Acute Myeloid Leukemia (AML) by Targeted Next-Generation Sequencing of 16 Leukemia-Related Genes Reveals Frequent Mutations Affecting Growth Factor Signalling Pathways and Provides Evidence for Clonal Heterogeneity

W. Hiddemann, K. Metzeler, S. Bohlander, 2012 .

A fluorescence in situ hybridization‐based screen allows rapid detection of adverse cytogenetic alterations in patients with acute myeloid leukemia

W. Hiddemann, K. Metzeler, S. Bohlander, 2017, Genes, chromosomes & cancer.

Acute Myeloid Leukemia With Isolated Trisomy 13 Is a Genetically Homogenous Entity With a High Frequency Of Mutations In Genes Encoding Components Of The Splicing Machinery and Extremely Poor Prognosis

W. Hiddemann, K. Metzeler, S. Bohlander, 2013 .

Efficient identification of somatic mutations in acute myeloid leukaemia using whole exome sequencing of fingernail derived DNA as germline control

S. Bohlander, P. Browett, P. Kakadia, 2018, Scientific Reports.

Efficient identification of somatic mutations in acute myeloid leukaemia using whole exome sequencing of fingernail derived DNA as germline control

S. Bohlander, P. Browett, P. Kakadia, 2018, Scientific Reports.

Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study

S. Bohlander, J. Reynolds, A. Roberts, 2019, Blood.

Laboratory quality assessment of candidate gene panel testing for acute myeloid leukaemia: a joint ALLG / RCPAQAP initiative.

Anna L. Brown, S. Bohlander, M. Horan, 2020, Pathology.

Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia

H. Leonhardt, K. Spiekermann, S. Bohlander, 2011, Leukemia.

Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients

E. Hoster, W. Hiddemann, S. Bohlander, 2012, Annals of Hematology.

Early assessment of minimal residual disease in AML by flow cytometry during aplasia identifies patients at increased risk of relapse

E. Hoster, W. Hiddemann, S. Bohlander, 2014, Leukemia.

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

W. Hiddemann, S. Bohlander, H. Blum, 2012, Blood.

Biallelic ATP2B1 variants as a likely cause of a novel neurodevelopmental malformation syndrome with primary hypoparathyroidism

P. Kakadia, L. Riley, Meer Jacob Rahimi, 2023, European journal of human genetics : EJHG.

The FLT3ITD mRNA level has a high prognostic impact in NPM1 mutated, but not in NPM1 unmutated, AML with a normal karyotype.

E. Hoster, W. Hiddemann, S. Bohlander, 2012, Blood.

TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells

J. Pimanda, J. Thoms, P. Kakadia, 2024, Nature communications.