Yong Ai

发表

Nitrogen Mustards As Anticancer Chemotherapies: Historic Perspective, Current Developments, And Future Trends.

B. Diethelm‐Varela, Yong Ai, Dongdong Liang, 2019, Current topics in medicinal chemistry.

Attenuated Accumulation of Novel Fluorine (19F)-Labeled Bile Acid Analogues in Gallbladders of Fibroblast Growth Factor-15 (FGF15)-Deficient Mice.

J. Polli, J. Raufman, Su Xu, 2018, Molecular pharmaceutics.

Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM

Lili Niu, Yong Ai, L. Lan, 2017, Bioscience reports.

Novel hybrids derived from aspirin and chalcones potently suppress colorectal cancer in vitro and in vivo.

Yong Ai, Shan Lu, Obinna N Obianom, 2018, MedChemComm.

Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies.

S. Heyward, M. Xia, Linhao Li, 2019, European journal of medicinal chemistry.

Improving the solubility and antileukemia activity of Wnt/β-catenin signaling inhibitors by disrupting molecular planarity.

M. Xia, S. Sakamuru, Yong Ai, 2022, Bioorganic & medicinal chemistry.

Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 (BCL6) BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design

Alexander D. MacKerell, A. Melnick, T. Cierpicki, 2019 .

Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer.

Jide Tian, Yihua Zhang, C. Ren, 2016, Journal of medicinal chemistry.

BCL6 BTB‐specific inhibition via FX1 treatment reduces Tfh cells and reverses lymphoid follicle hyperplasia in Indian rhesus macaque (Macaca mulatta)

L. Montaner, R. Veazey, J. Salvino, 2020, Journal of medical primatology.

BCL6 Inhibitor-Mediated Downregulation of Phosphorylated SAMHD1 and T Cell Activation Are Associated with Decreased HIV Infection and Reactivation

L. Montaner, L. Azzoni, B. Howell, 2018, Journal of Virology.

Synthesis and in vitro antiproliferative evaluation of pyrimido[5,4-c]quinoline-4-(3H)-one derivatives.

Li-wu Fu, Yong‐ju Liang, Yong Ai, 2012, European journal of medicinal chemistry.

Synthesis and structure elucidation of five new pyrimido[5,4‐c]quinoline‐4(3H)‐one derivatives using 1D and 2D NMR spectroscopy

Yong Ai, Xinxiang Lei, Guangzhong Yang, 2010, Magnetic resonance in chemistry : MRC.

Synthesis and Biological Evaluation of Novel Olean-28,13β-lactams as Potential Antiprostate Cancer Agents.

Jide Tian, Yihua Zhang, H. Ji, 2015, Journal of medicinal chemistry.

Novel cinnamaldehyde-based aspirin derivatives for the treatment of colorectal cancer.

Yong Ai, Shan Lu, Obinna N Obianom, 2018, Bioorganic & medicinal chemistry letters.

Synthesis of CDDO-amino acid-nitric oxide donor trihybrids as potential antitumor agents against both drug-sensitive and drug-resistant colon cancer.

Jide Tian, Yihua Zhang, Yong Ai, 2015, Journal of medicinal chemistry.

Pyrazole-4-Carboxamide (YW2065): A Therapeutic Candidate for Colorectal Cancer via Dual Activities of Wnt/β-Catenin Signaling Inhibition and AMP-Activated Protein Kinase (AMPK) Activation.

M. Xia, S. Sakamuru, Hong Yang, 2019, Journal of medicinal chemistry.

Molecular Modeling Studies of 4,5-Dihydro-1H-pyrazolo[4,3-h] quinazoline Derivatives as Potent CDK2/Cyclin A Inhibitors Using 3D-QSAR and Docking

Yong Ai, Ping-Hua Sun, Shao-Teng Wang, 2010, International journal of molecular sciences.

Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.

Alexander D. MacKerell, A. Melnick, T. Cierpicki, 2018, Journal of medicinal chemistry.

Enhanced Tumor Selectivity of 5-Fluorouracil Using a Reactive Oxygen Species-Activated Prodrug Approach.

Yan Shu, Yue Li, Yong Ai, 2018, ACS medicinal chemistry letters.

Gallium (III) Salophen as a Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Acquisition.

A. Wilks, Yong Ai, F. Xue, 2020, ACS infectious diseases.

Triazole-Based Inhibitors of the Wnt/β-Catenin Signaling Pathway Improve Glucose and Lipid Metabolisms in Diet-Induced Obese Mice.

M. Xia, S. Sakamuru, Hong Yang, 2019, Journal of medicinal chemistry.

3D-QSAR and docking studies on pyridopyrazinones as BRAF inhibitors

Yong Ai, Ping-Hua Sun, Shao-Teng Wang, 2011, Medicinal Chemistry Research.

Progress toward B-Cell Lymphoma 6 BTB Domain Inhibitors for the Treatment of Diffuse Large B-Cell Lymphoma and Beyond.

A. Melnick, A. MacKerell, Yong Ai, 2021, Journal of medicinal chemistry.

Molecular Modeling Studies on 11H-Dibenz[b,e]azepine and Dibenz[b,f][1,4]oxazepine Derivatives as Potent Agonists of the Human TRPA1 Receptor

Qiang Sun, Yong Ai, Ping-Hua Sun, 2010, Molecules.

Triterpenoid from Lycopodium obscurum L.

Yong Ai, Guangzhong Yang, Yu Chen, 2009, Yao xue xue bao = Acta pharmaceutica Sinica.