S. Ganapathy-Kanniappan

发表

Preclinical Benefit of Hypoxia-Activated Intra-arterial Therapy with Evofosfamide in Liver Cancer

Toby C. Cornish, J. Geschwind, MingDe Lin, 2016, Clinical Cancer Research.

Tumor glycolysis as a target for cancer therapy: progress and prospects

J. Geschwind, S. Ganapathy-Kanniappan, Jean-Francois H Geschwind, 2013, Molecular Cancer.

GAPDH with NAD+-binding site mutation competitively inhibits the wild-type and affects glucose metabolism in cancer.

S. Ganapathy-Kanniappan, R. Kunjithapatham, Shanmugasundaram Ganapathy-Kanniappan, 2018, Biochimica et biophysica acta. General subjects.

High-Resolution Ultrasound in Research of Mouse Orthotopic Glioma and Ultrasound-Guided Cell Implant

V. P. Chacko, J. Geschwind, MingDe Lin, 2011 .

Molecular intricacies of aerobic glycolysis in cancer: current insights into the classic metabolic phenotype

S. Ganapathy-Kanniappan, Shanmugasundaram Ganapathy-Kanniappan, 2018, Critical reviews in biochemistry and molecular biology.

The pyruvic acid analog 3-bromopyruvate interferes with the tetrazolium reagent MTS in the evaluation of cytotoxicity.

J. Geschwind, S. Ganapathy-Kanniappan, S. Ota, 2010, Assay and drug development technologies.

Editorial: Cancer Metabolism: Molecular Targeting and Implications for Therapy

S. Ganapathy-Kanniappan, 2017, Front. Oncol..

PFKP phenotype in lung cancer: prognostic potential and beyond.

S. Ganapathy-Kanniappan, 2020, Molecular biology reports.

3-Bromopyruvate induces endoplasmic reticulum stress, overcomes autophagy and causes apoptosis in human HCC cell lines.

J. Geschwind, R. Loffroy, S. Ganapathy-Kanniappan, 2010, Anticancer research.

Is There an Opportunity for Current Chemotherapeutics to Up-regulate MIC-A/B Ligands?

S. Ganapathy-Kanniappan, Kendel Quirk, 2017, Front. Pharmacol..

Isotopic Tracer Techniques in Preclinical Research

S. Ganapathy-Kanniappan, Shanmugasundaram Ganapathy-Kanniappan, 2022, Techniques in Life Science and Biomedicine for the Non-Expert.

Tumor cells and memory T cells converge at glycolysis

J. Geschwind, S. Ganapathy-Kanniappan, S. Karthikeyan, 2014, Cancer biology & therapy.

Spontaneous tumor regression in a syngeneic rat model of liver cancer: implications for survival studies.

J. Geschwind, S. Ganapathy-Kanniappan, S. Ota, 2012, Journal of vascular and interventional radiology : JVIR.

Systemic administration of 3-bromopyruvate reveals its interaction with serum proteins in a rat model

R. Cole, J. Geschwind, T. Boronina, 2013, BMC Research Notes.

Statins impair glucose uptake in tumor cells

J. Geschwind, S. Ganapathy-Kanniappan, R. Kunjithapatham, 2013, Cancer biology & therapy.

Anticancer efficacy of the metabolic blocker 3-bromopyruvate: specific molecular targeting.

J. Geschwind, S. Ganapathy-Kanniappan, R. Kunjithapatham, 2013, Anticancer research.

Selective Inhibition of Lactate Influx in Cancer: An Opportunity toAugment Therapeutic Targeting

S. Ganapathy-Kanniappan, 2016 .

Is the pathway of energy metabolism modified in advanced cirrhosis?

J. Geschwind, S. Ganapathy-Kanniappan, E. Mezey, 2014, Journal of hepatology.

3-bromopyruvate: a new targeted antiglycolytic agent and a promise for cancer therapy.

R. Loffroy, S. Ganapathy-Kanniappan, S. Ota, 2010, Current pharmaceutical biotechnology.

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death.

R. Cole, J. Geschwind, Irina Tchernyshyov, 2009, Anticancer research.

Analysis of GAPDH Enzyme Activity: A Quantitative and Qualitative Approach

S. Ganapathy-Kanniappan, 2017 .

Occurrence of a multimeric high-molecular-weight glyceraldehyde-3-phosphate dehydrogenase in human serum.

R. Cole, J. Geschwind, M. Torbenson, 2015, Journal of proteome research.

pI Determination of Native Proteins In Biological Samples

S. Ganapathy-Kanniappan, Shanmugasundaram Ganapathy-Kanniappan, 2019, Current protocols in protein science.

Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists.

J. Geschwind, M. Torbenson, K. Carson, 2012, Radiology.

Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer

B. Vogelstein, G. Semenza, P. Tran, 2014, Clinical Cancer Research.

Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma

J. Geschwind, S. Ganapathy-Kanniappan, R. Kunjithapatham, 2012, Oncotarget.

Evolution of GAPDH as a druggable target of tumor glycolysis?

S. Ganapathy-Kanniappan, 2018, Expert opinion on therapeutic targets.

Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model

J. Geschwind, D. Fu, S. Ganapathy-Kanniappan, 2014, Scientific Reports.

Ultrasound-guided direct delivery of 3-bromopyruvate blocks tumor progression in an orthotopic mouse model of human pancreatic cancer

J. Geschwind, S. Ganapathy-Kanniappan, S. Ota, 2013, Targeted Oncology.

Elevated mitochondrial activity distinguishes fibrogenic hepatic stellate cells and sensitizes for selective inhibition by mitotropic doxorubicin

K. Hong, A. Lavasanifar, S. Ganapathy-Kanniappan, 2018, Journal of cellular and molecular medicine.

Rac1 repression reverses chemoresistance by targeting tumor metabolism

S. Ganapathy-Kanniappan, 2020, Cancer biology & therapy.

Purification of GAPDH

S. Ganapathy-Kanniappan, 2017 .

Metabolic perturbation sensitizes human breast cancer to NK cell-mediated cytotoxicity by increasing the expression of MHC class I chain-related A/B

J. Geschwind, D. Fu, S. Ganapathy-Kanniappan, 2015, Oncoimmunology.

Linking tumor glycolysis and immune evasion in cancer: Emerging concepts and therapeutic opportunities.

S. Ganapathy-Kanniappan, Shanmugasundaram Ganapathy-Kanniappan, 2017, Biochimica et biophysica acta. Reviews on cancer.

Targeting Glycolytic Adaptations of Cancer Cells: From Molecular Mechanisms to Therapeutic Opportunities

S. Ganapathy-Kanniappan, Shanmugasundaram Ganapathy-Kanniappan, 2015 .

Taming Tumor Glycolysis and Potential Implications for Immunotherapy

S. Ganapathy-Kanniappan, Shanmugasundaram Ganapathy-Kanniappan, 2017, Front. Oncol..

A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia

M. McDevitt, L. Leng, R. Bucala, 2015, The Journal of experimental medicine.

Analysis of Subcellular and Extracellular GAPDH

S. Ganapathy-Kanniappan, 2017 .

Analysis of GAPDH and Protein Interaction

S. Ganapathy-Kanniappan, 2017 .

Cancer Therapy : Preclinical Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer

B. Vogelstein, G. Semenza, P. Tran, 2014 .

Turning cancer's metabolic plasticity into fragility- an evolving paradigm

S. Ganapathy-Kanniappan, Shanmugasundaram Ganapathy-Kanniappan, 2018, Cancer biology & therapy.

Augmented Liver Uptake of the Membrane Voltage Sensor Tetraphenylphosphonium Distinguishes Early Fibrosis in a Mouse Model

S. Ganapathy-Kanniappan, E. Mezey, Himanshi Pandita, 2021, Frontiers in Physiology.

Targeting tumor glycolysis by a mitotropic agent

S. Ganapathy-Kanniappan, 2016, Expert opinion on therapeutic targets.

Deregulation of energy metabolism promotes antifibrotic effects in human hepatic stellate cells and prevents liver fibrosis in a mouse model.

K. Kinzler, B. Vogelstein, J. Geschwind, 2016, Biochemical and biophysical research communications.