Vincent DiGiacomo

发表

Probing the mutational landscape of regulators of G protein signaling proteins in cancer

Vincent DiGiacomo, Marcin Maziarz, A. Luebbers, 2020, Science Signaling.

A biochemical and genetic discovery pipeline identifies PLC δ 4 b as a non-receptor activator of heterotrimeric G proteins

G. Baillie, J. Blanco-Canosa, Vincent DiGiacomo, 2018 .

Looking into laminin receptor: critical discussion regarding the non‐integrin 37/67‐kDa laminin receptor/RPSA protein

D. Meruelo, Vincent DiGiacomo, 2016, Biological reviews of the Cambridge Philosophical Society.

Enhanced Specific Delivery and Targeting of Oncolytic Sindbis Viral Vectors by Modulating Vascular Leakiness in Tumor

D. Meruelo, B. Levin, J. Tseng, 2009, Cancer Gene Therapy.

Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease

I. Dominguez, Anthony Leyme, Vincent DiGiacomo, 2016, Science Signaling.

The Gαi-GIV binding interface is a druggable protein-protein interaction

F. Blanco, Vincent DiGiacomo, M. Garcia-Marcos, 2017, Scientific Reports.

A biochemical and genetic discovery pipeline identifies PLC δ 4b as a non-receptor activator of heterotrimeric G proteins

G. Baillie, Vincent DiGiacomo, Marcin Maziarz, 2019 .

Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling*

Anthony Leyme, Vincent DiGiacomo, M. Garcia-Marcos, 2016, The Journal of Biological Chemistry.

The transition of the 37-kDa laminin receptor (RPSA) to higher molecular weight species: SUMOylation or artifact?

D. Meruelo, Ivan Gando, Vincent DiGiacomo, 2015, Cellular & molecular biology letters.

Mechanisms of aortic carboxypeptidase-like protein secretion and identification of an intracellularly retained variant associated with Ehlers–Danlos syndrome

Michael L. Smith, M. Layne, J. Wong, 2020, The Journal of Biological Chemistry.

Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression

A. Beeler, Vincent DiGiacomo, A. Luebbers, 2023, bioRxiv.

When Heterotrimeric G Proteins Are Not Activated by G Protein-Coupled Receptors: Structural Insights and Evolutionary Conservation.

Vincent DiGiacomo, M. Garcia-Marcos, A. Marivin, 2017, Biochemistry.

A biochemical and genetic discovery pipeline identifies PLCδ4b as a nonreceptor activator of heterotrimeric G-proteins

G. Baillie, J. Blanco-Canosa, Vincent DiGiacomo, 2018, The Journal of Biological Chemistry.

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

G. Baillie, F. Blanco, J. Blanco-Canosa, 2017, Nature Communications.

Evolutionary Conservation of a GPCR-Independent Mechanism of Trimeric G Protein Activation

M. Koelle, Vincent DiGiacomo, M. Garcia-Marcos, 2015, Molecular biology and evolution.

Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein

I. Dominguez, Anthony Leyme, Vincent DiGiacomo, 2017, Proceedings of the National Academy of Sciences.

DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi

E. Ross, J. Blanco-Canosa, Jingyi Zhao, 2020, The Journal of Biological Chemistry.

Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer

Aaron B. Beeler, Vincent DiGiacomo, A. Luebbers, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein

I. Dominguez, J. Blanco-Canosa, Anthony Leyme, 2017, Proceedings of the National Academy of Sciences.