P. Johansson

发表

Blood product ratio in acute traumatic coagulopathy - effect on mortality in a Scandinavian level 1 trauma centre

J. Dirks, Henrik Jørgensen, Carsten H Jensen, 2010, Scandinavian journal of trauma, resuscitation and emergency medicine.

Coagulation monitoring of the bleeding traumatized patient

P. Johansson, 2012, Current opinion in anaesthesiology.

Light-quark and gluon jet discrimination in pp collisions at √s=7 TeV with the ATLAS detector

J. T. Childers, Chang Wei Loh, H. S. Bansil, 2014, 1405.6583.

How I treat patients with massive hemorrhage.

C. Wade, J. Holcomb, S. Ostrowski, 2014, Blood.

Impact of Albumin on Coagulation Competence and Hemorrhage During Major Surgery

N. Secher, T. Pedersen, P. Johansson, 2016, Medicine.

Coagulopathy in patients with acute pulmonary embolism: a pilot study of whole blood coagulation and markers of endothelial damage

L. Bang, J. Carlsen, P. Olsen, 2017, Scandinavian journal of clinical and laboratory investigation.

Prediction of non-recovery from ventilator-demanding acute respiratory failure, ARDS and death using lung damage biomarkers: data from a 1200-patient critical care randomized trial

J. Vestbo, J. Lundgren, H. C. Boesen, 2016, Annals of Intensive Care.

Effects of red blood cell storage time on transfused patients in the ICU—protocol for a systematic review

J. Wetterslev, A. Perner, M. Madsen, 2017, Acta anaesthesiologica Scandinavica.

Red blood cell storage duration and long‐term mortality in patients undergoing cardiac intervention: a Danish register study

L. Lönn, T. Engstrøm, P. Johansson, 2017, Transfusion medicine.

Transfusion practice in hip arthroplasty – a nationwide study

H. Kehlet, P. Johansson, Z. Hussain, 2011, Vox sanguinis.

Assessment of coagulopathy, endothelial injury, and inflammation after traumatic brain injury and hemorrhage in a porcine model

L. Rasmussen, G. Velmahos, H. Alam, 2014, The journal of trauma and acute care surgery.

Reappraising the concept of massive transfusion in trauma

M. Cohen, J. Pittet, S. Stanworth, 2010, Critical care.

The central blood volume as measured by thoracic electrical impedance and plasma proANP is not compromised by donation of 900 mL of blood in men

N. Secher, N. Nordsborg, J. Goetze, 2020, Transfusion medicine.

Higher Thrombelastograph platelet reactivity in cardiac surgery patients than in blood donors

D. Steinbrüchel, P. Johansson, L. Bochsen, 2007, Scandinavian cardiovascular journal : SCJ.

An Untargeted Urine Metabolomics Approach for Autologous Blood Transfusion Detection

N. Secher, N. Nordsborg, L. Dragsted, 2020, Medicine and science in sports and exercise.

Anticoagulation, Resuscitation, and Hemostasis

P. Johansson, 2014 .

Coagulopathy and hemostatic monitoring in cardiac surgery: An update

S. Ostrowski, P. Johansson, J. Stensballe, 2012, Scandinavian cardiovascular journal : SCJ.

Current management of massive hemorrhage in trauma

S. Ostrowski, P. Johansson, J. Stensballe, 2012, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Definition and drivers of acute traumatic coagulopathy: clinical and experimental investigations

C. Thiemermann, M. Cohen, S. Stanworth, 2010, Journal of thrombosis and haemostasis : JTH.

Management of bleeding in major burn surgery.

S. Ostrowski, P. Johansson, J. White, 2019, Burns : journal of the International Society for Burn Injuries.

Data-driven Development of ROTEM and TEG Algorithms for the Management of Trauma Hemorrhage: A Prospective Observational Multicenter Study.

S. Stanworth, M. Maegele, K. Brohi, 2019, Annals of surgery.

Thrombelastography early amplitudes in bleeding and coagulopathic trauma patients: Results from a multicenter study

P. Naess, S. Ostrowski, P. Johansson, 2017, The journal of trauma and acute care surgery.

Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: an international prospective validation study

S. Stanworth, K. Brohi, P. Naess, 2015, Critical Care.

Damage control resuscitation using blood component therapy in standard doses has a limited effect on coagulopathy during trauma hemorrhage

S. Stanworth, K. Brohi, S. Glasgow, 2014, Intensive Care Medicine.

Changes in fibrinogen availability and utilization in an animal model of traumatic coagulopathy

C. Gaarder, Y. Gundersen, S. Ostrowski, 2013, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Trauma-induced coagulopathy: standard coagulation tests, biomarkers of coagulopathy, and endothelial damage in patients with traumatic brain injury.

L. Rasmussen, S. Ostrowski, P. Johansson, 2013, Journal of neurotrauma.

Hemostatic resuscitation with plasma and platelets in trauma

S. Ostrowski, P. Johansson, R. Oliveri, 2012, Journal of emergencies, trauma, and shock.

High circulating adrenaline levels at admission predict increased mortality after trauma

L. Rasmussen, S. Ostrowski, P. Johansson, 2012, The journal of trauma and acute care surgery.

Reduced clot strength upon admission, evaluated by thrombelastography (TEG), in trauma patients is independently associated with increased 30-day mortality

P. Johansson, K. Nystrup, N. A. Windeløv, 2011, Scandinavian journal of trauma, resuscitation and emergency medicine.

Effect of valproic acid and injury on lesion size and endothelial glycocalyx shedding in a rodent model of isolated traumatic brain injury

H. Alam, A. Perner, S. Ostrowski, 2014, The journal of trauma and acute care surgery.

Blood transfusion in the surgical treatment of adolescent idiopathic scoliosis—a single‐center experience of patient blood management in 210 cases

J. Dirks, P. Johansson, J. Stensballe, 2017, Transfusion.

Emerging treatment strategies for trauma‐induced coagulopathy (Br J Surg 2012; 99(Suppl 1): 40–50)

P. Johansson, P. Johansson, 2012, The British journal of surgery.

Hemostatic function of buffy coat platelets in additive solution treated with pathogen reduction technology

S. Ostrowski, P. Johansson, R. Goodrich, 2011, Transfusion.

The influence of platelets, plasma and red blood cells on functional haemostatic assays

A. Kristensen, G. Daugaard, S. Ostrowski, 2011, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Management of major blood loss: An update

N. Secher, S. Ostrowski, P. Johansson, 2010, Acta anaesthesiologica Scandinavica.

Transfusion practice in massively bleeding patients: time for a change?

M. B. Hansen, P. Johansson, Henrik Toft Sørensen, 2005, Vox sanguinis.

REVIEWS: Hemostatic resuscitation for massive bleeding: the paradigm of plasma and platelets—a review of the current literature

P. Johansson, J. Stensballe, 2009, Transfusion.

Hydroxyethyl Starch Reduces Coagulation Competence and Increases Blood Loss During Major Surgery: Results From a Randomized Controlled Trial

N. Secher, T. Pedersen, P. Johansson, 2014, Annals of surgery.

Effect of heat stress on cardiac output and systemic vascular conductance during simulated hemorrhage to presyncope in young men.

N. Secher, C. Crandall, M. S. Ganio, 2012, American journal of physiology. Heart and circulatory physiology.

Early activation of the coagulation system during lower body negative pressure

N. Secher, C. Crandall, L. Nielsen, 2009, Clinical physiology and functional imaging.

Understanding the Causes and Implications of Endothelial Metabolic Variation in Cardiovascular Disease through Genome-Scale Metabolic Modeling

Ó. Rolfsson, P. Johansson, S. McGarrity, 2016, Front. Cardiovasc. Med..

Flavor tagged time-dependent angular analysis of the B[0 over s] → J/ψϕ decay and extraction of ΔΓ[subscript s] and the weak phase ϕ[subscript s] in ATLAS

J. T. Childers, Chang Wei Loh, H. S. Bansil, 2014 .

The in vitro effect of recombinant factor VIIa on coated platelet formation and clot dynamics of stored platelet concentrates

A. Kristensen, P. Johansson, José A Salado-Jimena, 2009, Transfusion.

Investigation of the thrombin‐generating capacity, evaluated by thrombogram, and clot formation evaluated by thrombelastography of platelets stored in the blood bank for up to 7 days

J. Salado, A. Kristensen, P. Johansson, 2007, Vox sanguinis.

The Influence of Low Platelet Count on Whole Blood Aggregometry Assessed by Multiplate

S. Ostrowski, P. Johansson, N. Dridi, 2011, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Thrombelastographic haemostatic status and antiplatelet therapy after coronary artery bypass surgery (TEG-CABG trial): assessing and monitoring the antithrombotic effect of clopidogrel and aspirin versus aspirin alone in hypercoagulable patients: study protocol for a randomized controlled trial

K. Kofoed, M. Zacho, D. Steinbrüchel, 2012, Trials.

Detection of tPA-Induced Hyperfibrinolysis in Whole Blood by RapidTEG, KaolinTEG, and Functional FibrinogenTEG in Healthy Individuals

S. Ostrowski, P. Johansson, A. M. Sørensen, 2012, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Prehospital plasma is associated with distinct biomarker expression following injury.

F. Guyette, Y. Vodovotz, J. Sperry, 2020, JCI insight.

Towards patient‐specific management of trauma hemorrhage: the effect of resuscitation therapy on parameters of thromboelastometry

S. Stanworth, M. Maegele, K. Brohi, 2019, Journal of thrombosis and haemostasis : JTH.

Traumatic brain injury is associated with increased syndecan-1 shedding in severely injured patients

Ryan S. Kitagawa, J. Holcomb, C. Cox, 2018, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Traumatic Endotheliopathy: A Prospective Observational Study of 424 Severely Injured Patients

C. Wade, J. Holcomb, B. Cotton, 2016, Annals of surgery.

Early haemorrhage control and management of trauma-induced coagulopathy: the importance of goal-directed therapy

P. Johansson, J. Stensballe, H. H. Henriksen, 2017, Current opinion in critical care.

The use of viscoelastic haemostatic assays in goal-directing treatment with allogeneic blood products – A systematic review and meta-analysis

P. Johansson, R. Oliveri, Mathilde Fahrendorff, 2017, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Impact of blood products on platelet function in patients with traumatic injuries: a translational study.

E. Fox, C. Wade, J. Holcomb, 2017, The Journal of surgical research.

Haemostatic resuscitation in trauma: the next generation

S. Ostrowski, P. Johansson, J. Stensballe, 2016, Current opinion in critical care.

Hypercoagulability in patients undergoing coronary artery bypass grafting: prevalence, patient characteristics and postoperative outcome.

D. Steinbrüchel, S. Rafiq, S. Ostrowski, 2012, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Preoperative hemostatic testing and the risk of postoperative bleeding in coronary artery bypass surgery patients

K. Kofoed, D. Steinbrüchel, S. Rafiq, 2016, Journal of cardiac surgery.

Equally increased hypercoagulability irrespective of using minimized or conventional ECC systems

D. Steinbrüchel, S. Rafiq, P. Johansson, 2012, Scandinavian cardiovascular journal : SCJ.

Thrombelastographic hypercoagulability and antiplatelet therapy after coronary artery bypass surgery (TEG-CABG trial): a randomized controlled trial

K. Kofoed, D. Steinbrüchel, S. Rafiq, 2017, Platelets.

Coagulation competence and fluid recruitment after moderate blood loss in young men

N. Secher, F. Pott, P. Johansson, 2014, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The volume-expanding effects of autologous liquid stored plasma following hemorrhage

P. Johansson, U. Schött, P. Bentzer, 2012, Scandinavian journal of clinical and laboratory investigation.

Getting hit by the bus around the world – a global perspective on goal directed treatment of massive hemorrhage in trauma

P. Meybohm, E. Moore, K. Zacharowski, 2021, Current opinion in anaesthesiology.

Psychopharmacologic treatment and blood transfusion in fast‐track total hip and knee arthroplasty

H. Kehlet, A. Fink-Jensen, P. Johansson, 2017, Transfusion.

Measurement of isolated-photon plus two-jet production in pp collisions at √s=13 TeV with the ATLAS detector

Hoang Dai Nghia Nguyen, W. Y. Chan, A. S. Mete, 2020 .

Transfusion therapy in paediatric trauma patients: a review of the literature

S. Ostrowski, P. Johansson, J. Stensballe, 2015, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

How I Treat How I treat patients with massive hemorrhage

C. Wade, J. Holcomb, S. Ostrowski, 2014 .

Pre-hospital transfusion of plasma in hemorrhaging trauma patients independently improves hemostatic competence and acidosis

C. Wade, J. Holcomb, B. Cotton, 2016, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Intraoperative platelet and plasma improves survival in patients operated for a rAAA: a follow-up evaluation.

N. Secher, P. Johansson, F. Swiatek, 2008, European Journal of Vascular and Endovascular Surgery.

Use of red blood cells in Danish intensive care units: A population‐based register study

J. Anhøj, A. Perner, M. Møller, 2019, Acta anaesthesiologica Scandinavica.

Sympathoadrenal Activation and Endothelial Damage Are Inter Correlated and Predict Increased Mortality in Patients Resuscitated after Out-Of-Hospital Cardiac Arrest. A Post Hoc Sub-Study of Patients from the TTM-Trial

C. Hassager, J. Bro-Jeppesen, J. Kjaergaard, 2015, PloS one.

Effects of shorter versus longer storage time of transfused red blood cells in adult ICU patients: a systematic review with meta-analysis and Trial Sequential Analysis

J. Wetterslev, A. Perner, M. Madsen, 2018, Intensive Care Medicine.

A retrospective cohort study of blood hemoglobin levels in blood donors and competitive rowers

H. Ullum, N. Secher, P. Johansson, 2008, Scandinavian journal of medicine & science in sports.

The prognostic value of thrombelastography in identifying neurosurgical patients with worse prognosis

S. Ostrowski, P. Johansson, K. Welling, 2011, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

In-vitro comparison of free oscillation rheometry (ReoRox) and rotational thromboelastometry (ROTEM) in trauma patients upon hospital admission

S. Ostrowski, P. Johansson, J. Nielsen, 2012, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Evidence supporting the use of recombinant activated factor VII in congenital bleeding disorders

S. Ostrowski, P. Johansson, 2010, Drug design, development and therapy.

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine Thrombelastography and Tromboelastometry in Assessing Coagulopathy in Trauma

S. Ostrowski, P. Johansson, L. Bochsen, 2022 .

Thromboelastographic evaluation of hemostatic function in dogs with disseminated intravascular coagulation.

A. L. Jensen, A. Kristensen, P. Johansson, 2008, Journal of veterinary internal medicine.

Perioperative transfusion threshold and ambulation after hip revision surgery – a randomized trial

L. Rasmussen, P. Johansson, J. Børglum, 2014, BMC Anesthesiology.

Intraoperative transfusion threshold and tissue oxygenation: a randomised trial

L. Rasmussen, L. Rasmussen, S. Henneberg, 2012, Transfusion medicine.

Hypercoagulability in relation to coronary artery bypass graft patency and clinical outcome

M. Nielsen, K. Kofoed, H. Kelbæk, 2013, Scandinavian cardiovascular journal : SCJ.

Massive haemorrhage: a current perspective

S. Ostrowski, P. Johansson, 2012 .

The haematocrit--an important factor causing impaired haemostasis in patients with cyanotic congenital heart disease.

K. Sørensen, P. Johansson, L. Søndergaard, 2013, International journal of cardiology.

Fresh-frozen plasma resuscitation after traumatic brain injury and shock attenuates extracellular nucleosome levels and deoxyribonuclease 1 depletion.

L. Rasmussen, H. Alam, H. Albadawi, 2013, Surgery.

Successful pulmonary administration of activated recombinant factor VII in diffuse alveolar hemorrhage

H. Sengeløv, M. Levi, L. Heslet, 2006, Critical care.

Exploratory Investigation of the Plasma Proteome Associated with the Endotheliopathy of Trauma

Ó. Rolfsson, C. Pedroza, P. Johansson, 2022, International journal of molecular sciences.

Association between biomarkers of endothelial injury and hypocoagulability in patients with severe sepsis: a prospective study

A. Perner, F. Pott, M. Møller, 2015, Critical Care.

Viscoelastic guidance of resuscitation

S. Ostrowski, P. Johansson, J. Stensballe, 2014, Current opinion in anaesthesiology.

Coagulopathy, catecholamines, and biomarkers of endothelial damage in experimental human endotoxemia and in patients with severe sepsis: a prospective study.

K. Møller, S. Ostrowski, P. Johansson, 2013, Journal of critical care.

Rescue treatment with recombinant factor VIIa is effective in patients with life-threatening bleedings secondary to major wound excision: a report of four cases.

P. Johansson, B. Alsbjørn, K. Eriksen, 2006, The Journal of trauma.

The use of recombinant activated factor VII in patients undergoing major burn surgery: experiences from a single center

P. Johansson, B. Alsbjørn, K. Eriksen, 2006 .

Tailored antiplatelet therapy to improve prognosis in patients exhibiting clopidogrel low-response prior to percutaneous coronary intervention for stable angina or non-ST elevation acute coronary syndrome

T. Engstrøm, L. Holmvang, M. Radu, 2015, Platelets.

Off‐label use of recombinant factor VIIa for treatment of haemorrhage: results from randomized clinical trials

P. Johansson, P. Johansson, 2008, Vox sanguinis.

Evaluation of the TEG® platelet mapping™ assay in blood donors

D. Steinbrüchel, M. Kjelgaard‐Hansen, P. Johansson, 2007, Thrombosis Journal.

Absences of Endothelial Microvesicle Changes in the Presence of the Endotheliopathy of Trauma

C. Wade, J. Holcomb, B. Cotton, 2019, Shock.

Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

K. Nakahira, M. McGeachie, A. Rogers, 2018, Critical Care.

Blood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after trauma

L. Rasmussen, S. Ostrowski, P. Johansson, 2013, Journal of emergencies, trauma, and shock.

The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients.

T. Jones, M. Maegele, K. Brohi, 2019, Annals of surgery.

Thromboembolic Complications in Fontan Patients: Population-Based Prevalence and Exploration of the Etiology

K. Sørensen, S. Ostrowski, P. Johansson, 2013, Pediatric Cardiology.

DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors

H. Ullum, J. Olesen, T. Werge, 2019, BMJ Open.

The anticoagulant effect of therapeutic levels of dabigatran in atrial fibrillation evaluated by thrombelastography (TEG®), Hemoclot Thrombin Inhibitor (HTI) assay and Ecarin Clotting Time (ECT)

S. Ostrowski, P. Johansson, J. Stensballe, 2018, Scandinavian journal of clinical and laboratory investigation.

Thromboelastography on plasma reveals delayed clot formation and accelerated clot lyses in HIV-1 infected persons compared with healthy controls

H. Ullum, S. Ostrowski, P. Johansson, 2015, BMC Infectious Diseases.

Abnormalities of laboratory coagulation tests versus clinically evident coagulopathic bleeding: results from the prehospital resuscitation on helicopters study (PROHS)

Thomas J Greene, P. Rhee, G. van Belle, 2018, Surgery.

Transfusion packages for massively bleeding patients: the effect on clot formation and stability as evaluated by Thrombelastograph (TEG).

N. Secher, P. Johansson, J. Stensballe, 2008, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

Investigation of the effect of kaolin and tissue factor–activated citrated whole blood, on clot forming variables, as evaluated by thromboelastography

D. Viuff, P. Johansson, L. Bochsen, 2008, Transfusion.

The blood bank: from provider to partner in treatment of massively bleeding patients

P. Johansson, P. Johansson, 2007, Transfusion.

Treatment of massively bleeding patients: introducing real‐time monitoring, transfusion packages and thrombelastography (TEG®)

P. Johansson, P. Johansson, Pär I. Johansson, 2007 .

Differential clot stabilising effects of rFVIIa and rFXIII‐A2 in whole blood from thrombocytopenic patients and healthy volunteers

D. Viuff, P. Johansson, L. C. Petersen, 2008, British journal of haematology.

Effect of acute hypobaric hypoxia on the endothelial glycocalyx and digital reactive hyperemia in humans

N. Nordsborg, S. Ostrowski, P. Johansson, 2014, Front. Physiol..

Severe mesenteric traction syndrome is associated with increased systemic inflammatory response, endothelial dysfunction, and major postoperative morbidity

M. Achiam, P. Johansson, L. Svendsen, 2021, Langenbeck's Archives of Surgery.

Metabolic systems analysis identifies a novel mechanism contributing to shock in patients with endotheliopathy of trauma (EoT) involving thromboxane A2 and LTC4

C. Wade, I. Marín de Mas, P. Johansson, 2022, Matrix biology plus.

Orthostatic intolerance during early mobilization after fast-track hip arthroplasty.

H. Kehlet, P. Johansson, Ø. Jans, 2012, British journal of anaesthesia.

Transfusion of 7‐day‐old amotosalen photochemically treated buffy‐coat platelets to patients with thrombocytopenia: a pilot study

P. Johansson, N. Borregaard, Lily Lin, 2006, Transfusion.

Fibrinogen function is impaired in whole blood from patients with cyanotic congenital heart disease.

K. Sørensen, P. Johansson, L. Søndergaard, 2013, International journal of cardiology.

Hyaluronic Acid Is a Biomarker for Allograft Dysfunction and Predicts 1-Year Graft Loss After Liver Transplantation.

J. Lundgren, S. Ostrowski, P. Johansson, 2018, Transplantation proceedings.

Discrepant Fibrinolytic Response in Plasma and Whole Blood during Experimental Endotoxemia in Healthy Volunteers

K. Møller, S. Ostrowski, P. Johansson, 2013, PloS one.

Acute myocardial infarction is associated with endothelial glycocalyx and cell damage and a parallel increase in circulating catecholamines

S. Pedersen, J. Jensen, S. Ostrowski, 2013, Critical Care.

Resuscitation speed affects brain injury in a large animal model of traumatic brain injury and shock

H. Alam, P. Johansson, G. Jin, 2014, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Estimating the effect of donor sex on red blood cell transfused patient mortality: A retrospective cohort study using a targeted learning and emulated trials-based approach

S. Brunak, P. Andersen, K. Banasik, 2022, EClinicalMedicine.

Effects of nucleotides and nucleosides on coagulation

J. Rosenmeier, P. Johansson, P. Thaning, 2010, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Transfusion requirements and clinical outcome in intensive care patients receiving continuous renal replacement therapy: comparison of prostacyclin vs. heparin prefilter administration

A. Perner, S. Ostrowski, P. Johansson, 2010, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Platelet aggregation following trauma: a prospective study

L. Rasmussen, A. Perner, S. Ostrowski, 2014, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Real-life experiences with goal-directed prohemostatic therapy with fibrinogen concentrate, prothrombin complex concentrate, and recombinant factor VIIa: a retrospective study of 287 consecutive patients

P. Johansson, J. Stensballe, Martin Vigstedt, 2022, Scandinavian journal of clinical and laboratory investigation.

A review of the clinical utility of INR to monitor and guide administration of prothrombin complex concentrate to orally anticoagulated patients

S. Ostrowski, P. Johansson, Sacha Sølbeck, 2012, Thrombosis Journal.

O R I G I N a L C L I N I C a L I N V E S T I G a T I O N Open Access

S. Ostrowski, P. Johansson, Sacha Sølbeck, 2022 .

Platelet increment is not associated with endothelial damage in haematological patients: a prospective observational study

S. Ostrowski, P. Johansson, U. Schött, 2019, Scandinavian journal of clinical and laboratory investigation.

Lipidomic Signatures Align with Inflammatory Patterns and Outcomes in Critical Illness

Upendra K. Kar, C. Callaway, A. Cyr, 2021, Nature Communications.

The effect of intraoperative and 6-h postoperative intravenous administration of low-dose prostacyclin on the endothelium, hemostasis, and hemodynamics in patients undergoing a pancreaticoduodenoctemy: a randomized-controlled pilot study

C. Hansen, S. Ostrowski, P. Johansson, 2017, European journal of gastroenterology & hepatology.

The effect of prostacyclin infusion on markers of endothelial activation and damage in mechanically ventilated patients with SARS-CoV-2 infection

T. Lange, A. Perner, M. Bestle, 2022, Journal of Critical Care.

Managing the bleeding emergency in a patient with red cell antibodies

P. Johansson, M. Dziegiel, K. Rieneck, 2016 .

Profound Endothelial Damage Predicts Impending Organ Failure and Death in Sepsis

J. Lundgren, J. Jensen, M. Bestle, 2015, Seminars in Thrombosis & Hemostasis.

Evaluation of the systemic inflammatory response, endothelial cell dysfunction, and postoperative morbidity in patients, receiving perioperative corticosteroid, developing severe mesenteric traction syndrome — an exploratory study

M. Achiam, P. Johansson, L. Svendsen, 2022, Langenbeck's Archives of Surgery.

Rethinking platelet function: thrombocytopenia induced immunodeficiency in critical illness.

S. Ostrowski, P. Johansson, 2011, Medical hypotheses.

Low dose Iloprost effect on platelet aggregation in comatose out-of-hospital cardiac arrest patients: A predefined sub-study of the ENDO-RCA randomized -phase 2- trial.

C. Hassager, S. Ostrowski, P. Johansson, 2019, Journal of critical care.

Platelet hyperreactivity in response to on- and off-pump coronary artery bypass grafting.

D. Steinbrüchel, P. Johansson, L. Bochsen, 2009, The journal of extra-corporeal technology.

Is a more aggressive antithrombotic therapy warranted after coronary artery bypass grafting?: O-06

D. Steinbrüchel, P. Johansson, L. Bochsen, 2007 .

Transfusion requirements in elective cardiopulmonary bypass surgery patients: predictive value of Multiplate and Thromboelastography (TEG) Platelet Mapping Assay

S. Ostrowski, P. Johansson, H. Ravn, 2017, Scandinavian journal of clinical and laboratory investigation.

Dabigatran and its reversal with recombinant factor VIIa and prothrombin complex concentrate: A Sonoclot in vitro study

S. Ostrowski, P. Johansson, M. Engström, 2014, Scandinavian journal of clinical and laboratory investigation.

Monitoring of dabigatran anticoagulation and its reversal in vitro by thrombelastography.

B. Cotton, S. Ostrowski, P. Johansson, 2014, International journal of cardiology.

Hemostatic strategies for minimizing mortality in surgery with major blood loss

P. Johansson, 2009, Current opinion in hematology.

Influence of cardiopulmonary bypass on the interaction of recombinant factor VIIa with activated platelets.

P. Johansson, M. Kjalke, R. Røjkjaer, 2009, The journal of extra-corporeal technology.

Level of systemic inflammation and endothelial injury is associated with cardiovascular dysfunction and vasopressor support in post-cardiac arrest patients.

C. Hassager, J. Bro-Jeppesen, J. Kjaergaard, 2017, Resuscitation.

effect of targeted temperature management on coagulation arameters and bleeding events after out-of-hospital cardiac arrest of resumed cardiac cause

C. Hassager, J. Bro-Jeppesen, S. Ostrowski, 2015 .

Effect of delayed onset prostacyclin on markers of endothelial function and damage after subarachnoid hemorrhage

S. Ostrowski, P. Johansson, J. Stensballe, 2017, Acta Neurochirurgica.

Lower versus higher hemoglobin threshold for transfusion in septic shock.

V. Pettilä, J. Wernerman, J. Wetterslev, 2014, The New England journal of medicine.

Thrombelastography (TEG® 6s) early amplitudes predict maximum amplitude in severely injured trauma patients

M. Maegele, K. Brohi, C. Gaarder, 2022, Scandinavian journal of clinical and laboratory investigation.

Monitoring compliance with transfusion guidelines in hospital departments by electronic data capture.

P. Johansson, A. Nørgaard, Trine Honnens De Lichtenberg, 2014, Blood transfusion = Trasfusione del sangue.

Resuscitation with Pooled and Pathogen-Reduced Plasma Attenuates the Increase in Brain Water Content following Traumatic Brain Injury and Hemorrhagic Shock in Rats.

S. Ostrowski, P. Johansson, P. Bentzer, 2017, Journal of neurotrauma.

Fibrinogen in trauma, an evaluation of thrombelastography and rotational thromboelastometry fibrinogen assays.

C. Wade, J. Holcomb, S. Ostrowski, 2015, The Journal of surgical research.

High Plasma Levels of Neuropeptide Y Correlate With Good Clinical Outcome But are not Correlated to Cerebral Blood Flow or Vasospasm After Subarachnoid Hemorrhage

J. Skjøth-Rasmussen, S. Ostrowski, P. Johansson, 2016, Journal of neurosurgical anesthesiology.

Hepcidin and Erythroferrone Complement the Athlete Biological Passport in the Detection of Autologous Blood Transfusion

N. Secher, N. Nordsborg, T. Ganz, 2022, Medicine and science in sports and exercise.

In vitro efficacy of RiaSTAP after rapid reconstitution.

C. Wade, J. Holcomb, B. Cotton, 2014, The Journal of surgical research.

Interindividual variation in platelets and the cardiovascular response to haemorrhage in the pig

N. Secher, P. Rasmussen, P. Johansson, 2011, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Vox Sanguinis International Forum on the use of prehospital blood products and pharmaceuticals in the treatment of patients with traumatic haemorrhage

H. Russcher, D. Jenkins, H. Doughty, 2018, Vox sanguinis.

A High Admission Syndecan-1 Level, A Marker of Endothelial Glycocalyx Degradation, Is Associated With Inflammation, Protein C Depletion, Fibrinolysis, and Increased Mortality in Trauma Patients

L. Rasmussen, S. Ostrowski, P. Johansson, 2011, Annals of surgery.

Acute coagulopathy of trauma: balancing progressive catecholamine induced endothelial activation and damage by fluid phase anticoagulation.

S. Ostrowski, P. Johansson, 2010, Medical hypotheses.

Sympathoadrenal activation and endotheliopathy are drivers of hypocoagulability and hyperfibrinolysis in trauma: A prospective observational study of 404 severely injured patients

C. Wade, J. Holcomb, B. Cotton, 2017, The journal of trauma and acute care surgery.

Fibrinogen concentrates in bleeding trauma patients

P. Johansson, P. Johansson, M. Meyer, 2012 .

Endothelial glycocalyx degradation induces endogenous heparinization in patients with severe injury and early traumatic coagulopathy

S. Ostrowski, P. Johansson, 2012, The journal of trauma and acute care surgery.

High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality

M. Wanscher, A. Perner, S. Ostrowski, 2012, Journal of thrombosis and haemostasis : JTH.

High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

A. Perner, S. Ostrowski, P. Johansson, 2012, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

In vitro cell quality of buffy coat platelets in additive solution treated with pathogen reduction technology

H. Ullum, S. Ostrowski, P. Johansson, 2010, Transfusion.

Thrombelastography and biomarker profiles in acute coagulopathy of trauma: a prospective study

S. Ostrowski, P. Johansson, A. M. Sørensen, 2011, Scandinavian journal of trauma, resuscitation and emergency medicine.

Managing patients on direct factor Xa inhibitors with rapid thrombelastography

P. Johansson, M. Dziegiel, J. Stensballe, 2021, Scandinavian journal of clinical and laboratory investigation.

Efficacy and safety of iloprost in trauma patients with haemorrhagic shock‐induced endotheliopathy—Protocol for the multicentre randomized, placebo‐controlled, blinded, investigator‐initiated shine‐trauma trial

T. Lange, H. Kirkegaard, C. Gaarder, 2021, Acta anaesthesiologica Scandinavica.

Circulating levels of platelet α-granule cytokines in trauma patients

L. Rasmussen, S. Ostrowski, P. Johansson, 2015, Inflammation Research.

Treatment with a histone deacetylase inhibitor, valproic acid, is associated with increased platelet activation in a large animal model of traumatic brain injury and hemorrhagic shock.

H. Alam, C. Boer, P. Johansson, 2014, The Journal of surgical research.

Coagulopathy Underlying Rotational Thromboelastometry Derangements in Trauma Patients: A Prospective Observational Multicenter Study

M. Maegele, K. Brohi, C. Gaarder, 2022, Anesthesiology.

Shock-Driven Endotheliopathy in Trauma Patients Is Associated with Leucocyte Derived Extracellular Vesicles

R. Nieuwland, E. van der Pol, M. Maegele, 2022, International journal of molecular sciences.

Recombinant FVIIa decreases perioperative blood transfusion requirement in burn patients undergoing excision and skin grafting--results of a single centre pilot study.

S. Nielsen, P. Johansson, B. Alsbjørn, 2007, Burns : journal of the International Society for Burn Injuries.

Hypercoagulability in response to elevated body temperature and central hypovolemia.

N. Secher, C. Crandall, S. Ostrowski, 2013, The Journal of surgical research.

Goal-directed hemostatic resuscitation for massively bleeding patients: the Copenhagen concept.

P. Johansson, 2010, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

Effects of fresh frozen plasma, Ringer’s acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats

P. Johansson, U. Schött, P. Bentzer, 2016, Intensive Care Medicine Experimental.

Tissue factor activated thromboelastography correlates to clinical signs of bleeding in dogs.

A. L. Jensen, M. Kjelgaard‐Hansen, A. Kristensen, 2009, Veterinary journal.

Endothelial Damage Signals Refractory Acute Kidney Injury in Critically Ill Patients

J. Lundgren, J. Jensen, M. Bestle, 2017, Shock.

A randomized trial of the effect of low dose epinephrine infusion in addition to tranexamic acid on blood loss during total hip arthroplasty.

H. Kehlet, P. Johansson, H. Mandøe, 2016, British journal of anaesthesia.

Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism

S. Ostrowski, P. Johansson, J. Stensballe, 2017, Critical Care.

Validation of human recombinant tissue factor-activated thromboelastography on citrated whole blood from clinically healthy dogs.

A. L. Jensen, M. Kjelgaard‐Hansen, A. Kristensen, 2005, Veterinary clinical pathology.

Plasma as a resuscitation fluid for volume‐depleted shock: Potential benefits and risks

Kimberly A. Thomas, J. Sperry, P. Spinella, 2021, Transfusion.

Pilot Randomized trial of Fibrinogen in Trauma Haemorrhage (PRooF-iTH): study protocol for a randomized controlled trial

Theis Lange, T. Lange, J. Steinmetz, 2016, Trials.

The wound healing effect of local leukocyte platelet‐rich plasma after total hip arthroplasty: A randomized controlled trial

J. R. Andersen, P. Johansson, M. Ågren, 2021, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Syndecan-1: A Quantitative Marker for the Endotheliopathy of Trauma.

C. Wade, J. Holcomb, B. Cotton, 2017, Journal of the American College of Surgeons.

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

J. Holcomb, S. Ostrowski, P. Johansson, 2015, Journal of Translational Medicine.

The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients.

T. Jones, M. Maegele, K. Brohi, 2019, Annals of surgery.

A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome

H. Stefánsson, D. Gudbjartsson, T. Thorgeirsson, 2022, Nature Communications.

Study on biological variation of haemostatic parameters in clinically healthy dogs.

A. L. Jensen, M. Kjelgaard‐Hansen, A. Kristensen, 2007, Veterinary journal.

Thrombelastography and rotational thromboelastometry early amplitudes in 182 trauma patients with clinical suspicion of severe injury

L. Rasmussen, C. Wade, J. Holcomb, 2014, The journal of trauma and acute care surgery.

Low hemorrhage‐related mortality in trauma patients in a Level I trauma center employing transfusion packages and early thromboelastography‐directed hemostatic resuscitation with plasma and platelets

A. Perner, S. Ostrowski, P. Johansson, 2013, Transfusion.

Evaluation of TEG(®) and RoTEM(®) inter-changeability in trauma patients.

M. Cohen, J. Røislien, Morten Hestnes, 2013, Injury.

Effect of Haemostatic Control Resuscitation on mortality in massively bleeding patients: a before and after study

P. Johansson, J. Stensballe, 2008, Vox sanguinis.

Consecutive thrombelastography clot strength profiles in patients with severe sepsis and their association with 28-day mortality: a prospective study.

A. Perner, S. Ostrowski, P. Johansson, 2013, Journal of critical care.

Hypocoagulability, as evaluated by thrombelastography, at admission to the ICU is associated with increased 30-day mortality

A. Perner, K. Espersen, P. Johansson, 2010, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificity.

A. L. Jensen, M. Kjelgaard‐Hansen, A. Kristensen, 2010, Veterinary journal.

Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification

Ó. Rolfsson, A. Bergmann, S. Halldorsson, 2018, Scientific Reports.

The Potential of Antimicrobials to Induce Thrombocytopenia in Critically Ill Patients: Data from a Randomized Controlled Trial

J. Lundgren, J. Jensen, M. Bestle, 2013, PloS one.

Role of preoperative anemia for risk of transfusion and postoperative morbidity in fast‐track hip and knee arthroplasty

H. Kehlet, P. Johansson, Ø. Jans, 2014, Transfusion.

Endothelial glycocalyx shedding in patients with burns.

C. Wade, P. Johansson, J. Stensballe, 2019, Burns : journal of the International Society for Burn Injuries.

Redefining massive transfusion

J. Pittet, S. Stanworth, M. Maegele, 2009, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial

M. Maegele, K. Brohi, C. Gaarder, 2020, Intensive Care Medicine.

ESICM LIVES 2016: part two

A. M. Cavalheiro, H. S. King, M. M. Moraes, 2016, Intensive Care Medicine Experimental.

Early Identification of the Patient with Endotheliopathy of Trauma by Arrival Serum Albumin

C. Wade, J. Holcomb, B. Cotton, 2017, Shock.

Normal saline influences coagulation and endothelial function after traumatic brain injury and hemorrhagic shock in pigs.

H. Alam, C. Boer, P. Johansson, 2014, Surgery.

How biomarkers reflect the prognosis and treatment of necrotising soft tissue infections and the effects of hyperbaric oxygen therapy: the protocol of the prospective cohort PROTREAT study conducted at a tertiary hospital in Copenhagen, Denmark

O. Hyldegaard, P. Johansson, Peter Polzik, 2017, BMJ Open.

High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)

K. Abel, M. Leist, A. Kirkeby, 2008, Thrombosis and Haemostasis.

A pilot study to assess the hemostatic function of pathogen‐reduced platelets in patients with thrombocytopenia

S. Ostrowski, P. Johansson, R. Goodrich, 2013, Transfusion.

Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology

Laurent F. Thomas, J. V. van Meurs, R. Mägi, 2022, Nature Communications.

Intervening on the storage time of RBC units and its effects on adverse recipient outcomes using real-world data

S. Brunak, P. Andersen, K. Banasik, 2022, Blood.

ABO blood types and sepsis mortality

J. Lundgren, D. Sessler, A. Khanna, 2021, Annals of Intensive Care.

Plasma Concentration of Biomarkers Reflecting Endothelial Cell- and Glycocalyx Damage are Increased in Patients With Suspected ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock

C. Hassager, J. Kjaergaard, L. Holmvang, 2018, Shock.

Markers of endothelial damage and coagulation impairment in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs Ringer acetate.

J. Wetterslev, A. Perner, S. Ostrowski, 2016, Journal of critical care.

Sympathoadrenal activation and endothelial damage in patients with varying degrees of acute infectious disease: an observational study.

C. Pedersen, S. Ostrowski, P. Johansson, 2015, Journal of critical care.

Association between sympathoadrenal activation, fibrinolysis, and endothelial damage in septic patients: a prospective study.

Anders Perner, Nicolai Haase, A. Perner, 2014, Journal of critical care.

Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses

Upendra K. Kar, S. Wisniewski, A. Cyr, 2021, Cell reports. Medicine.

A Systemic Storm in Critically Injured Humans Revealed by Longitudinal Multi-Omics

Upendra K. Kar, S. Wisniewski, A. Cyr, 2021 .

Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases

L. Lönn, M. Nielsen, P. Johansson, 2014, European Spine Journal.

Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy

A. Schubert, N. Juffermans, M. Maegele, 2017, The British journal of surgery.

Hypercoagulation Assessed by Thromboelastography is Neither Related to Infarct Size nor to Clinical Outcome After Primary Percutaneous Coronary Intervention

T. Engstrøm, L. Holmvang, M. Radu, 2014, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Metabolic Response in Endothelial Cells to Catecholamine Stimulation Associated with Increased Vascular Permeability

Ó. Rolfsson, A. Bergmann, C. Wade, 2022, International journal of molecular sciences.

High syndecan-1 levels in acute myeloid leukemia are associated with bleeding, thrombocytopathy, endothelial cell damage, and leukocytosis.

H. Birgens, S. Ostrowski, P. Johansson, 2013, Leukemia research.

Erratum to: Shock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanism

S. Ostrowski, P. Johansson, J. Stensballe, 2017, Critical Care.

Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat

S. Ostrowski, P. Johansson, M. Hansen, 2018, The journal of trauma and acute care surgery.

Platelet activation and dysfunction in a large‐animal model of traumatic brain injury and hemorrhage

L. Rasmussen, G. Velmahos, Michael J. Duggan, 2013, The journal of trauma and acute care surgery.

II. Bringing flow into haemostasis diagnostics.

P. Johansson, U. Schött, Pär I. Johansson, 2013, British journal of anaesthesia.

Fresh frozen plasma resuscitation attenuates platelet dysfunction compared with normal saline in a large animal model of multisystem trauma

L. Rasmussen, G. Velmahos, Michael J. Duggan, 2014, The journal of trauma and acute care surgery.

Endothelial dysfunction and thromboembolism in children, adolescents, and young adults with acute lymphoblastic leukemia

K. Schmiegelow, R. Tuckuviene, Ó. Jónsson, 2021, Leukemia.

Postoperative anemia and early functional outcomes after fast‐track hip arthroplasty: a prospective cohort study

H. Kehlet, T. Bandholm, P. Johansson, 2016, Transfusion.

Higher vs. lower haemoglobin threshold for transfusion in septic shock: subgroup analyses of the TRISS trial

J. Wetterslev, A. Perner, P. Johansson, 2017, Acta anaesthesiologica Scandinavica.

Proactive administration of platelets and plasma for patients with a ruptured abdominal aortic aneurysm: evaluating a change in transfusion practice

N. Secher, P. Johansson, J. Stensballe, 2007, Transfusion.

Plasma Resuscitation Improved Survival in a Cecal Ligation and Puncture Rat Model of Sepsis

C. Wade, J. Holcomb, M. Schreiber, 2018, Shock.

Endotheliopathy is associated with slower liberation from mechanical ventilation: a cohort study

M. Bestle, P. Johansson, T. Itenov, 2022, Critical Care.

Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients

N. Secher, Ó. Rolfsson, I. Marín de Mas, 2023, International journal of molecular sciences.

Identified metabolic signature for assessing red blood cell unit quality is associated with endothelial damage markers and clinical outcomes

B. Palsson, A. Bordbar, Ó. Rolfsson, 2016, Transfusion.

Metabolic Systems Analysis of Shock-Induced Endotheliopathy (SHINE) in Trauma

B. Palsson, Ó. Rolfsson, C. Wade, 2019, Annals of surgery.

Long-term outcomes in patients with septic shock transfused at a lower versus a higher haemoglobin threshold: the TRISS randomised, multicentre clinical trial

J. Wernerman, J. Wetterslev, A. Perner, 2016, Intensive Care Medicine.

Thrombelastography detects dabigatran at therapeutic concentrations in vitro to the same extent as gold-standard tests.

S. Ostrowski, P. Johansson, J. Stensballe, 2016, International journal of cardiology.

Storage time of red blood cells among ICU patients with septic shock

H. Ullum, T. Lange, J. Wetterslev, 2019, Acta anaesthesiologica Scandinavica.

Recombinant erythropoietin acutely decreases renal perfusion and decouples the renin‐angiotensin‐aldosterone system

P. Oturai, N. Holstein-Rathlou, P. Johansson, 2018, Physiological reports.

Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study

T. Eken, M. Cohen, J. Røislien, 2014, Critical Care.

Prasugrel or double-dose clopidogrel to overcome clopidogrel low-response – The TAILOR (Thrombocytes And IndividuaLization of ORal antiplatelet therapy in percutaneous coronary intervention) randomized trial

T. Engstrøm, L. Holmvang, M. Radu, 2014, Platelets.

Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study

Anders Perner, A. Perner, S. Ostrowski, 2011, Critical care.

Resuscitation of Endotheliopathy and Bleeding in Thoracic Aortic Dissections: The VIPER-OCTA Randomized Clinical Pilot Trial

P. Olsen, S. Ostrowski, P. Johansson, 2018, Anesthesia and analgesia.

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

C. Wade, J. Holcomb, R. Bruhn, 2015, Journal of Translational Medicine.

Major open abdominal surgery is associated with increased levels of endothelial damage and interleukin-6.

M. Achiam, P. Johansson, H. Sørensen, 2023, Microvascular research.

Transfusion requirements in septic shock (TRISS) trial - comparing the effects and safety of liberal versus restrictive red blood cell transfusion in septic shock patients in the ICU: protocol for a randomised controlled trial

V. Pettilä, J. Wernerman, N. Nielsen, 2013, Trials.

A randomised double-blind pilot trial comparing a mean arterial pressure target of 65 mm Hg versus 72 mm Hg after out-of-hospital cardiac arrest

C. Hassager, J. Kjaergaard, S. Ostrowski, 2020, European heart journal. Acute cardiovascular care.

Three‐year follow‐up of implementation of evidence‐based transfusion practice in a tertiary hospital

H. Sillesen, L. Kjeldsen, A. Perner, 2017, Vox Sanguinis.

Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity

A. Perner, S. Ostrowski, P. Johansson, 2012, Critical care medicine.

Efficacy and safety of iloprost in patients with septic shock‐induced endotheliopathy—Protocol for the multicenter randomized, placebo‐controlled, blinded, investigator‐initiated trial

T. Lange, A. Perner, M. Bestle, 2020, Acta anaesthesiologica Scandinavica.

Endothelial activation/injury and associations with severity of post-cardiac arrest syndrome and mortality after out-of-hospital cardiac arrest.

C. Hassager, J. Bro-Jeppesen, J. Kjaergaard, 2016, Resuscitation.

High Levels of Methylarginines Were Associated With Increased Mortality in Patients With Severe Sepsis

A. Perner, M. Bestle, S. Ostrowski, 2016, Shock.

Mild induced hypothermia: effects on sepsis-related coagulopathy--results from a randomized controlled trial.

J. Lundgren, J. Jensen, M. Bestle, 2015, Thrombosis research.

Thromboelastography in patients with severe sepsis: a prospective cohort study

T. Lange, J. Wetterslev, A. Perner, 2014, Intensive Care Medicine.

Administration of platelets to ruptured abdominal aortic aneurysm patients before open surgery: a prospective, single‐blinded, randomised study

N. Secher, H. Sillesen, P. Johansson, 2018, Transfusion medicine.

Low level of procoagulant platelet microparticles is associated with impaired coagulation and transfusion requirements in trauma patients

L. Rasmussen, A. Perner, S. Ostrowski, 2014, The journal of trauma and acute care surgery.

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine Thrombelastography and Tromboelastometry in Assessing Coagulopathy in Trauma

S. Ostrowski, P. Johansson, L. Bochsen, 2022 .

Reduced clot strength upon admission, evaluated by thrombelastography (TEG), in trauma patients is independently associated with increased 30-day mortality

P. Johansson, K. Nystrup, N. A. Windeløv, 2011, Scandinavian journal of trauma, resuscitation and emergency medicine.

A Protocol for the Automatic Construction of Highly Curated Genome-Scale Models of Human Metabolism

L. K. Nielsen, I. Marín de Mas, P. Johansson, 2023, Bioengineering.

Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification

Ó. Rolfsson, A. Bergmann, S. Halldorsson, 2018, Scientific Reports.

High-dimensional proteomics identifies organ injury patterns associated with outcomes in human trauma

Upendra K. Kar, J. Sperry, T. Billiar, 2023, The journal of trauma and acute care surgery.

Prevention and treatment of coagulopathy in patients receiving massive transfusions

S. Bélisle, C. Samama, R. Rossaint, 2011, Vox sanguinis.

Lipidomic signatures align with inflammatory patterns and outcomes in critical illness

Upendra K. Kar, F. Guyette, Y. Vodovotz, 2022, Nature communications.