F. Stewart

发表

Bidirectional Relationship between Functional Connectivity and Amyloid-β Deposition in Mouse Brain

Adam W. Bero, M. Raichle, D. Holtzman, 2012, The Journal of Neuroscience.

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

Guojun Bu, Steven Mennerick, David M. Holtzman, 2008, Neuron.

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

Jee Hoon Roh, Jin-Moo Lee, Marcus E. Raichle, 2011, Nature Neuroscience.

Human Apoe Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance Nih Public Access

David M Holtzman, Randall J Bateman, A. Fagan, 2022 .

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease

D. Holtzman, D. Holtzman, L. Lecea, 2014, The Journal of experimental medicine.

AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy

D. Holtzman, Hong Jiang, F. Stewart, 2017, The Journal of experimental medicine.

Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of β-Amyloid in Mice with Alzheimer’s Disease Pathology

Adam W. Bero, D. Holtzman, R. Bateman, 2012, Science Translational Medicine.

Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy

D. Holtzman, N. Cairns, A. Boxer, 2017, Science Translational Medicine.

Neuronal activity regulates extracellular tau in vivo

D. Holtzman, E. Mandelkow, J. Cirrito, 2014, The Journal of experimental medicine.

ApoE facilitates the microglial response to amyloid plaque pathology

D. Holtzman, K. Nilsson, M. Colonna, 2018, The Journal of experimental medicine.

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

D. Holtzman, M. Colonna, J. Ulrich, 2017, Proceedings of the National Academy of Sciences.

Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis

D. Holtzman, Hong Jiang, Jaekwang Kim, 2012, The Journal of experimental medicine.

Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP

Dean Nizetic, Andre Strydom, Henrik Zetterberg, 2018, Brain : a journal of neurology.

Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis

D. Holtzman, T. Esparza, J. Ulrich, 2017, Neuron.

Antisense Reduction of Tau in Adult Mice Protects against Seizures

D. Holtzman, F. Rigo, J. Cirrito, 2013, The Journal of Neuroscience.

Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer's disease.

D. Holtzman, K. Dikranian, F. Stewart, 2012, International journal of clinical and experimental pathology.

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease

D. Holtzman, D. Holtzman, L. Lecea, 2014, The Journal of experimental medicine.

In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice

D. Holtzman, V. Lee, E. Mandelkow, 2011, The Journal of Neuroscience.

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2

D. Holtzman, L. Piccio, M. Colonna, 2014, Molecular Neurodegeneration.

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis

Tim West, D. Holtzman, Andrew C. Paoletti, 2012, Proceedings of the National Academy of Sciences.

Analysis of in vivo turnover of tau in a mouse model of tauopathy

D. Holtzman, E. Mandelkow, Hong Jiang, 2015, Molecular Neurodegeneration.

Jee Hoon Roh in Mice with Alzheimer ' s Disease Pathology-Amyloid β Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of

Adam W. Bero, D. Holtzman, R. Bateman, 2013 .

Haploinsufficiency of Human APOE Reduces Amyloid Deposition in a Mouse Model of Amyloid-β Amyloidosis

D. Holtzman, Hong Jiang, Hyejin Yoon, 2011, The Journal of Neuroscience.

Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death

D. Holtzman, J. Milbrandt, J. Neil, 2011, Proceedings of the National Academy of Sciences.

Synaptic Transmission Dynamically Modulates Interstitial Fluid Amyloid-β Levels

D. Holtzman, J. Cirrito, S. Mennerick, 2008 .

Brief Definitive Report

D. Holtzman, B. J. Snider, M. Yanagisawa, 2003 .

Neuronal activity regulates extracellular tau in vivo.

D. Holtzman, E. Mandelkow, J. Cirrito, 2014, The Journal of experimental medicine.

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2

D. Holtzman, L. Piccio, M. Colonna, 2014, Molecular Neurodegeneration.

Neuronal activity regulates extracellular tau in vivo

D. Holtzman, D. Holtzman, E. Mandelkow, 2014, The Journal of experimental medicine.

β Peptide Clearance

A. Fagan, D. Holtzman, S. Paul, 2011 .

Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of β-Amyloid in Mice with Alzheimer’s Disease Pathology

Adam W. Bero, D. Holtzman, R. Bateman, 2012, Science Translational Medicine.

Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance

A. Fagan, D. Holtzman, S. Paul, 2011, Science Translational Medicine.