S. Chappell

发表

Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease

D. Hernandez, A. Singleton, J. Hardy, 2018, Neurobiology of Aging.

Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease

K. Morgan, J. Roca, W. MacNee, 2006 .

Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease

K. Morgan, J. Roca, W. MacNee, 2006, Human mutation.

Running Title: EPHX1 and GCL variation in COPD

K. Morgan, J. Roca, W. MacNee, 2008 .

The New Genetics and Chronic Obstructive Pulmonary Disease

N. Kalsheker, S. Chappell, 2008, COPD.

Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism.

K. Morgan, R. Bucala, C. Gallagher, 2005, American journal of respiratory and critical care medicine.

A polymorphism of the alpha1‐antitrypsin gene represents a risk factor for liver disease

K. Morgan, R. Stockley, N. Kalsheker, 2007, Hepatology.

Haplotypes of the alpha‐1 antitrypsin gene in healthy controls and Z deficiency patients

K. Morgan, W. MacNee, N. Kalsheker, 2004, Human mutation.

Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD

K. Morgan, J. Roca, W. MacNee, 2007, European Respiratory Journal.

Title : Polygenic risk score in post-mortem diagnosed sporadic early onset Alzheimer ’ s disease

D. Hernandez, A. Singleton, J. Hardy, 2018 .

Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease

K. Morgan, J. Roca, W. MacNee, 2006, Human mutation.

Altered transmission of maternal angiotensin II receptor haplotypes in fetal growth restriction

N. Kalsheker, P. Baker, S. Chappell, 2006, Human mutation.

PROTEINASE INHIBITORS | Antichymotrypsin

K. Morgan, N. Kalsheker, S. Chappell, 2006 .

Polygenic risk score in post-mortem diagnosed sporadic early onset Alzheimer’s disease

D. Hernandez, K. Morgan, J. Bras, 2017 .

The SERPINE2 gene and chronic obstructive pulmonary disease.

K. Morgan, J. Roca, W. MacNee, 2006, American journal of human genetics.

Screening Exon 16 and 17 of the Amyloid Precursor Protein Gene in Sporadic Early-Onset Alzheimer’s Disease (sEOAD)

A. Singleton, K. Morgan, D. Mann, 2016 .

Investigating Splicing Variants Uncovered by Next-Generation Sequencing the Alzheimer’s Disease Candidate Genes, CLU, PICALM, CR1, ABCA7, BIN1, the MS4A Locus, CD2AP, EPHA1 and CD33

K. Morgan, P. Passmore, D. Mann, 2016 .

The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

K. Morgan, J. Roca, W. MacNee, 2011, BMC Medical Genetics.

The alpha-1-antitrypsin gene promoter in human A549 lung derived cells, and a novel transcription initiation site.

K. Morgan, N. Kalsheker, S. Chappell, 2009, The international journal of biochemistry & cell biology.

Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population

K. Morgan, J. Roca, W. MacNee, 2010, BMC Medical Genetics.

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

D. Lawlor, U. Thorsteinsdóttir, K. Stefánsson, 2017 .

Copy Number Variation of the Beta-Defensin Genes in Europeans: No Supporting Evidence for Association with Lung Function, Chronic Obstructive Pulmonary Disease or Asthma

L. Wain, I. Sayers, M. Tobin, 2014, PloS one.

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array

D. Hernandez, A. Singleton, J. Hardy, 2017, Neurobiology of Aging.

Scavenger receptor class B type I genetic variants associated with disease severity in chronic hepatitis C virus infection

K. Morgan, A. Tarr, J. Ball, 2022, Journal of medical virology.

Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset

D. Hernandez, A. Singleton, D. Neary, 2015 .

Searching for genetic clues to the causes of pre-eclampsia.

S. Chappell, L. Morgan, 2006, Clinical science.

Methylation Profiling RIN3 and MEF2C Identifies Epigenetic Marks Associated with Sporadic Early Onset Alzheimer’s Disease

K. Morgan, J. Craigon, G. Seymour, 2017, Journal of Alzheimer's disease reports.

Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene and the rate of cognitive decline in Alzheimer's disease.

K. Morgan, D. Warden, N. Kalsheker, 2007, Human molecular genetics.

The hydroxy-methyl-glutaryl CoA reductase promoter polymorphism is associated with Alzheimer's risk and cognitive deterioration

M. Franceschi, K. Morgan, E. Porcellini, 2007, Neuroscience Letters.

Effects of Alzheimer's peptide and alpha1-antichymotrypsin on astrocyte gene expression.

K. Morgan, L. Minthon, N. Kalsheker, 2007, Neurobiology of aging.

Molecular Genetics of Chronic Obstructive Pulmonary Disease

N. Kalsheker, S. Chappell, 2010 .

Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD

K. Morgan, J. Roca, W. MacNee, 2008, European Respiratory Journal.

A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD

A. Ritchie, K. Morgan, A. Smith, 2008, Neurobiology of Aging.

Transforming growth factor beta1 regulates angiotensin II type I receptor gene expression in the extravillous trophoblast cell line SGHPL-4.

K. Morgan, N. Kalsheker, P. Baker, 2005, Molecular human reproduction.

Observations of extensive gene expression differences in the cerebellum and potential relevance to Alzheimer’s disease

K. Morgan, P. Francis, K. Brookes, 2018, BMC Research Notes.

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12

Blair H. Smith, L. Wain, I. Ntalla, 2016, Thorax.

Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population

K. Morgan, J. Roca, W. MacNee, 2010, BMC Medical Genetics.

in MOCS 3 , IFIT 3 and SERPINA 12

Blair H. Smith, L. Wain, I. Ntalla, 2016 .

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

D. Lawlor, U. Thorsteinsdóttir, K. Stefánsson, 2017, Nature Genetics.

Angiotensinogen gene variants and small‐for‐gestational‐age infants

N. Kalsheker, P. Baker, S. Chappell, 2006, BJOG : an international journal of obstetrics and gynaecology.

Effects of Alzheimer ' s peptide and alpha 1-antichymotrypsin on astrocyte gene expression

L. Minthon, N. Kalsheker, S. Chappell, 2016 .

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array

D. Warden, C. Medway, H. Kölsch, 2017, Neurobiology of Aging.

Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease

D. Neary, P. Passmore, J. Snowden, 2016, Neurobiology of Aging.

Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's

C. Medway, H. Kölsch, A. Richardson, 2015 .

Polymorphism in the endoplasmic reticulum mannosidase I (MAN1B1) gene is not associated with liver disease in individuals homozygous for the Z variant of the alpha1‐antitrypsin protease inhibitor (PiZZ individuals)

R. Stockley, N. Kalsheker, N. Hadžić, 2009, Hepatology.

Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population

S. Monti, S. Chappell, J. Lotya, 2010, BMC Medical Genetics.

Edinburgh Research Explorer Association of MMP-12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population

S. Monti, M. Miniati, S. Chappell, 2022 .

Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population

S. Monti, S. Chappell, J. Lotya, 2010, BMC Medical Genetics.