J. Simpson

发表

Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease.

L. Wood, P. Gibson, V. McDonald, 2011, American journal of respiratory and critical care medicine.

Airway monocyte modulation relates to tumour necrosis factor dysregulation in neutrophilic asthma

H. Scott, P. Gibson, K. Baines, 2021, ERJ Open Research.

Neutrophilic asthma features increased airway classical monocytes

H. Scott, P. Gibson, K. Baines, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

C. Jenkins, A. James, S. Hodge, 2017, The Lancet.

Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma

Jodie L Simpson, Katherine J Baines, Peter G Gibson, 2015, European Respiratory Journal.

Neutrophilic asthma is characterised by increased rhinosinusitis with sleep disturbance and GERD.

P. Gibson, K. Baines, N. Ryan, 2013, Asian Pacific journal of allergy and immunology.

Participant demographics and sputum cell counts from participants with neutrophilic , eosinophilic and paucigranulocytic asthma

P. Gibson, K. Baines, N. Ryan, 2014 .

Occupational exposures, smoking and airway inflammation in refractory asthma

M. Guest, M. Boggess, P. Gibson, 2014, BMC Pulmonary Medicine.

Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma

P. Gibson, L. Gunawardhana, H. Powell, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Oxidized vitamin E and glutathione as markers of clinical status in asthma.

L. Wood, M. Garg, P. Gibson, 2008, Clinical nutrition.

Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma

L. Wood, R. Scott, P. Gibson, 2011, Thorax.

Sputum transcriptomics implicates increased p38 signalling activity in severe asthma

L. Wood, P. Gibson, K. Baines, 2019, Respirology.

Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples.

Jodie L Simpson, Katherine J Baines, Rodney J Scott, 2011, The Journal of allergy and clinical immunology.

Inflammatory mediators in exhaled breath, induced sputum and saliva

L. Wood, P. Gibson, J. Simpson, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma

P. Gibson, S. Johnston, P. Gibson, 2002, European Respiratory Journal.

Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease

P. Foster, P. Gibson, M. Smyth, 2007, Nature Medicine.

Periostin levels and eosinophilic inflammation in poorly-controlled asthma

C. Jenkins, A. James, S. Hodge, 2016, BMC Pulmonary Medicine.

Sputum basophils are increased in eosinophilic asthma compared with non‐eosinophilic asthma phenotypes

J. Douwes, P. Gibson, I. Hermans, 2017, Allergy.

Soluble RAGE is deficient in neutrophilic asthma and COPD

L. Wood, P. Gibson, P. Gibson, 2011, European Respiratory Journal.

Full blood count parameters for the detection of asthma inflammatory phenotypes

P. Gibson, C. Jenkins, A. James, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Influence of Age, Past Smoking, and Disease Severity on TLR2, Neutrophilic Inflammation, and MMP-9 Levels in COPD

P. Gibson, K. Baines, V. McDonald, 2013, Mediators of inflammation.

Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: a randomized controlled trial.

P. McElduff, P. Gibson, N. Saltos, 2003, The Journal of allergy and clinical immunology.

Galectin-3: its role in asthma and potential as an anti-inflammatory target

P. Gibson, J. Simpson, Jie Zhang, 2013, Respiratory Research.

Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease

P. Foster, P. Gibson, P. Hansbro, 2011, PLoS pathogens.

COPD_A_222486 2517..2525

K. Baines, P. Wark, M. Fricker, 2019 .

Blood Neutrophils In COPD But Not Asthma Exhibit A Primed Phenotype With Downregulated CD62L Expression

K. Baines, P. Wark, M. Fricker, 2019, International journal of chronic obstructive pulmonary disease.

S100A12 provokes mast cell activation: a potential amplification pathway in asthma and innate immunity.

P. Hart, P. Gibson, C. Geczy, 2007, The Journal of allergy and clinical immunology.

Combination Inhaled Corticosteroids and Long-Acting Beta2-Agonists for Children and Adults with Bronchiectasis

A. Chang, P. Gibson, K. Baines, 2014 .

The European Network For Understanding Mechanisms Of Severe Asthma study

P. Gibson, J. Simpson, 2004, European Respiratory Journal.

Acute Asthma

P. Wark, J. Simpson, Alistair Cook, 2021, Reference Module in Biomedical Sciences.

The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma

C. Jenkins, A. James, G. Marks, 2020, European Respiratory Journal.

Patterns of azithromycin use in obstructive airway diseases: a real‐world observational study

P. Gibson, V. McDonald, J. Simpson, 2021, Internal medicine journal.

The Effect of Azithromycin in Adults with Stable Neutrophilic COPD: A Double Blind Randomised, Placebo Controlled Trial

H. Coxson, P. Gibson, K. Baines, 2014, PloS one.

Serum prednisolone levels as a marker of oral corticosteroid adherence in severe asthma

P. Wark, J. Simpson, R. Niven, 2020, BMC Pulmonary Medicine.

Airway inflammation in COPD: Is it worth measuring and is it clinically meaningful?

J. Simpson, 2020, Respirology.

Absence of airway inflammation in a large proportion of adolescents with asthma

J. Douwes, N. Pearce, P. Gibson, 2016, Respirology.

Assessment and Reproducibility of Non-Eosinophilic Asthma Using Induced Sputum

P. McElduff, P. Gibson, J. Simpson, 2009, Respiration.

Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis

K. Schroder, I. Masters, A. Chang, 2018, ERJ Open Research.

Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma

H. Scott, P. Gibson, K. Baines, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Characterization of innate immune signalling receptors in virus‐induced acute asthma

L. Wood, P. Gibson, P. Wark, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Eosinophilia as a treatable trait in three patients with asthma and COPD

P. Wark, J. Simpson, J. Ramsahai, 2018, Respirology case reports.

Neutrophilic asthma features increased airway classical monocytes

H. Scott, P. Gibson, K. Baines, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Blood cytotoxic/inflammatory mediators in non‐eosinophilic asthma

P. Gibson, A. James, S. Hodge, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Role for NLRP3 Inflammasome‐mediated, IL‐1&bgr;‐Dependent Responses in Severe, Steroid‐Resistant Asthma

L. Wood, P. Gibson, K. Baines, 2017, American journal of respiratory and critical care medicine.

Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD

P. Jones, P. Gibson, K. Baines, 2016, International journal of chronic obstructive pulmonary disease.

Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts

L. Wood, K. Chung, P. Gibson, 2022, Respirology.

New insights in neutrophilic asthma

S. Seys, D. Bullens, J. Simpson, 2019, Current opinion in pulmonary medicine.

Heterogeneity of airway inflammation in persistent asthma : evidence of neutrophilic inflammation and increased sputum interleukin-8.

P. Gibson, N. Saltos, J. Simpson, 2001, Chest.

Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma.

P. Gibson, R. Henry, M. Z. Norzila, 2000, American journal of respiratory and critical care medicine.

Pattern of airway inflammation and its determinants in children with acute severe asthma

P. Gibson, R. Henry, M. Z. Norzila, 1999, Pediatric pulmonology.

The role of exhaled nitric oxide and exhaled breath condensates in evaluating airway inflammation in asthma.

P. Wark, J. Simpson, 2008, Expert opinion on medical diagnostics.

Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease

P. Gibson, K. Baines, V. McDonald, 2021, Allergy.

Differential gene expression and cytokine production from neutrophils in asthma phenotypes

R. Scott, P. Gibson, K. Baines, 2009, European Respiratory Journal.

Induced sputum 8-isoprostane concentrations in inflammatory airway diseases.

L. Wood, M. Garg, Trevor A. Mori, 2005, American journal of respiratory and critical care medicine.

TNF-α and Macrophages Are Critical for Respiratory Syncytial Virus–Induced Exacerbations in a Mouse Model of Allergic Airways Disease

P. Foster, P. Gibson, K. Baines, 2016, The Journal of Immunology.

Different inflammatory phenotypes in adults and children with acute asthma

P. Gibson, K. Baines, L. Gunawardhana, 2011, European Respiratory Journal.

Airway inflammation in thunderstorm asthma

P. Gibson, P. Wark, M. Hensley, 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Alternatives to induced sputum for identifying inflammatory subtypes of asthma

M. Bafadhel, J. Simpson, 2017, Respirology.

Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma

P. Foster, P. Gibson, R. Kim, 2015, Thorax.

Impaired macrophage phagocytosis in non‐eosinophilic asthma

P. Gibson, A. James, J. Upham, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

A survey of specialist opinions on biomarker use in severe asthma in Australia: scepticism but hope?

P. Wark, L. Heaney, J. Simpson, 2020, ERJ Open Research.

Relationship between airway neutrophilia and ageing in asthmatics and non‐asthmatics

J. Douwes, P. Gibson, J. Simpson, 2013, Respirology.

Safety of sputum induction with isotonic saline in adults with acute severe asthma

P. Gibson, M. Hensley, J. Simpson, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Airway abundance of Haemophilus influenzae predicts response to azithromycin in adults with persistent uncontrolled asthma

P. Gibson, S. Taylor, G. Rogers, 2020, European Respiratory Journal.

Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study.

F. Blasi, J. Elborn, G. Rogers, 2021, The Lancet. Respiratory medicine.

Airway eosinophilia is associated with wheeze but is uncommon in children with persistent cough and frequent chest colds.

Anita C. Chalmers, P. Gibson, P. Wark, 2001, American journal of respiratory and critical care medicine.

COPD is characterized by increased detection of Haemophilus influenzae, Streptococcus pneumoniae and a deficiency of Bacillus species

P. Gibson, K. Baines, V. McDonald, 2016, Respirology.

Biology of neutrophils

P. Gibson, K. Baines, J. Simpson, 2009 .

Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: an exploratory study

K. Baines, P. Wark, J. Simpson, 2019, BMJ Open.

Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

Meilan K. Han, G. Washko, B. Suki, 2022, The Lancet.

COPD_A_245519 1577..1590

P. Gibson, K. Baines, V. McDonald, 2020 .

Effect of saliva contamination on induced sputum cell counts, IL‐8 and eosinophil cationic protein levels

P. Gibson, N. Timmins, J. Simpson, 2004, European Respiratory Journal.

Optimization of sputum‐processing methods for the measurement of interleukin‐5: Effects of protease inhibition

P. Gibson, P. Wark, P. Wark, 2002, Respirology.

Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy

P. Gibson, K. Baines, L. Gunawardhana, 2014, Pediatric pulmonology.

IMMUNE RESPONSES OF AIRWAY NEUTROPHILS ARE IMPAIRED IN ASTHMA

R. Scott, P. Gibson, K. Baines, 2009, Experimental lung research.

The tolerability, safety, and success of sputum induction and combined hypertonic saline challenge in children.

P. Gibson, R. Henry, J. Simpson, 2001, American journal of respiratory and critical care medicine.

Use of induced sputum for the diagnosis of influenza and infections in asthma: a comparison of diagnostic techniques

S. Johnston, P. Gibson, P. Wark, 2002, Journal of Clinical Virology.

Measurement of Cytokines in Induced Sputum

P. Gibson, J. Simpson, 2001 .

Mechanisms of cough

P. Gibson, A. Vertigan, N. Ryan, 2014, Current opinion in allergy and clinical immunology.

The overlap syndrome of asthma and COPD: what are its features and how important is it?

P. Gibson, J. Simpson, 2009, Thorax.

What does the increasing prevalence of obesity mean for the management of asthma and airways disease?

H. Scott, J. Simpson, 2020, Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia.

Sexually dimorphic production of interleukin‐6 in respiratory disease

V. McDonald, B. Oliver, J. Simpson, 2020, Physiological reports.

Sputum mast cell subtypes relate to inflammatory phenotype and steroid response of asthma

L. Wood, P. Gibson, K. Baines, 2016 .

Potentially pathogenic bacteria cultured from the sputum of stable asthmatics are associated with increased 8-isoprostane and airway neutrophilia

L. Wood, P. Gibson, P. Hansbro, 2010, Free radical research.

Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β

C. Jenkins, A. James, S. Hodge, 2015, Respiratory Research.

Outcomes of protracted bacterial bronchitis in children: A 5‐year prospective cohort study

I. Masters, A. Chang, S. Hodge, 2020, Respirology.

Relationship between induced sputum eosinophils and the clinical pattern of childhood asthma

P. Gibson, R. Henry, H. Powell, 2003, Thorax.

Combined Haemophilus influenzae respiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma

P. Foster, P. Gibson, P. Hansbro, 2012, Thorax.

Elevated expression of the NLRP3 inflammasome in neutrophilic asthma

S. Phipps, P. Gibson, K. Baines, 2013, European Respiratory Journal.

Add-on azithromycin reduces sputum cytokines in non-eosinophilic asthma: an AMAZES substudy

A. James, S. Hodge, P. Reynolds, 2021, Thorax.

Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma

L. Wood, P. Foster, D. Knight, 2017, Immunological reviews.

Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma.

C. Jenkins, A. James, S. Wesselingh, 2019, American journal of respiratory and critical care medicine.

Induced sputum IL-8 gene expression, neutrophil influx and MMP-9 in allergic bronchopulmonary aspergillosis

P. Gibson, N. Saltos, C. Meldrum, 2003, European Respiratory Journal.

Neutrophils in asthma: the good, the bad and the bacteria

E. Sapey, S. Taylor, G. Rogers, 2021, Thorax.

Sputum colour can identify patients with neutrophilic inflammation in asthma

L. Wood, P. Gibson, K. Baines, 2017, BMJ Open Respiratory Research.

Neutrophil extracellular traps are associated with inflammation in chronic airway disease

P. Gibson, K. Baines, V. McDonald, 2016, Respirology.

The Role of Lower Airway Dysbiosis in Asthma: Dysbiosis and Asthma

Shiji Wang, Zhong-min Liu, Jingtong Zheng, 2017, Mediators of inflammation.

Sputum ADAM8 expression is increased in severe asthma and COPD

L. Wood, P. Gibson, V. McDonald, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

Nabil T. Fadai, D. V. Nicolau, P. Barnes, 2021, The Lancet Respiratory Medicine.

Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice.

S. Akira, S. Phipps, P. Foster, 2013, The Journal of allergy and clinical immunology.

Innate immune activation in neutrophilic asthma and bronchiectasis

J. Douwes, R. Scott, P. Gibson, 2007, Thorax.

Inflammatory subtypes in asthma: Assessment and identification using induced sputum

R. Scott, P. Gibson, J. Simpson, 2006, Respirology.

Transcriptomics of biopsies identifies novel genes and pathways linked to neutrophilic inflammation in severe asthma

K. Baines, P. Wark, J. Simpson, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Innate Immune Responses Are Increased in Chronic Obstructive Pulmonary Disease

P. Gibson, K. Baines, J. Simpson, 2011, PloS one.

Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease

T. Coenye, A. Willems, M. Tunney, 2021, European Respiratory Journal.

Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma

L. Wood, P. Gibson, K. Baines, 2021, Thorax.

An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype

L. Wood, K. Chung, H. Scott, 2021, Allergy.

Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a mechanistic analysis

D. V. Nicolau, P. Barnes, L. Donnelly, 2022, The Lancet Respiratory Medicine.

Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma

M. Benton, R. Lea, P. Gibson, 2014, Epigenetics.

Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes.

L. Wood, R. Scott, P. Gibson, 2014, The Journal of allergy and clinical immunology.

Older peoples’ perception of tests used in the assessment and management of COPD and asthma

P. McElduff, P. Gibson, V. McDonald, 2013, The clinical respiratory journal.

Multidimensional assessment of older people with asthma and COPD: clinical management and health status.

P. Gibson, V. McDonald, I. Higgins, 2011, Age and ageing.

Heterogeneity of paucigranulocytic asthma: A prospective cohort study with hierarchical cluster analysis.

G. Wang, P. Gibson, M. Xie, 2021, The journal of allergy and clinical immunology. In practice.

A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD

P. Gibson, K. Baines, V. McDonald, 2020, International journal of chronic obstructive pulmonary disease.

Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma

K. Baines, P. Wark, J. Simpson, 2020, Immunity, inflammation and disease.

A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma.

C. Jenkins, A. James, G. Marks, 2019, The Journal of allergy and clinical immunology.

Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

C. Jenkins, A. James, S. Wesselingh, 2018, The Journal of allergy and clinical immunology.

Reduced Antiviral Interferon Production in Poorly Controlled Asthma Is Associated With Neutrophilic Inflammation and High-Dose Inhaled Corticosteroids.

A. James, S. Hodge, P. Reynolds, 2016, Chest.

Altered sputum granzyme B and granzyme B/proteinase inhibitor‐9 in patients with non‐eosinophilic asthma

A. James, S. Hodge, P. Reynolds, 2014, Respirology.

Neutrophilic asthma has different radiographic features to COPD and smokers.

P. Gibson, D. Milne, J. Simpson, 2009, Respiratory medicine.

Inhaled budesonide in the treatment of early COVID-19 illness: a randomised controlled trial

Nabil T. Fadai, D. V. Nicolau, T. Bengtsson, 2021, medRxiv.

ONCOSTATIN M (OSM) IS INCREASED IN ASTHMA WITH INCOMPLETELY REVERSIBLE AIRFLOW OBSTRUCTION

Jodie L Simpson, Katherine J Baines, Michael J Boyle, 2009, Experimental lung research.

Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD

P. Gibson, K. Baines, P. Hansbro, 2018, ERJ Open Research.

Clarithromycin targets neutrophilic airway inflammation in refractory asthma.

R. Scott, P. Gibson, H. Powell, 2008, American journal of respiratory and critical care medicine.

Randomised controlled trial for the titration of oral corticosteroids using markers of inflammation in severe asthma

P. Gibson, V. McDonald, P. Wark, 2023, Thorax.

The contribution of respiratory microbiome analysis to a treatable traits model of care

I. Yang, S. Taylor, G. Rogers, 2018, Respirology.

Longitudinal Changes in Clinical Outcomes in Older Patients with Asthma, COPD and Asthma-COPD Overlap Syndrome

P. Gibson, V. McDonald, J. Simpson, 2013, Respiration.

Efficacy of azithromycin in severe asthma from the AMAZES randomised trial

C. Jenkins, A. James, G. Marks, 2019, ERJ Open Research.

Systemic Inflammation in Older Adults With Asthma-COPD Overlap Syndrome

P. Gibson, V. McDonald, J. Simpson, 2012, Allergy, asthma & immunology research.

Inflammatory mechanisms and treatment of obstructive airway diseases with neutrophilic bronchitis.

S. Phipps, P. Gibson, J. Simpson, 2009, Pharmacology & therapeutics.

Innate immunity in asthma.

Jodie L Simpson, Jeroen Douwes, J. Douwes, 2008, Paediatric respiratory reviews.

Hip fracture risk and subsequent mortality among Alzheimer ’ s disease patients in the United Kingdom , 1988 – 2007

P. Gibson, V. McDonald, I. Higgins, 2010 .

Saturated fatty acids, obesity, and the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome in asthmatic patients

L. Wood, H. Scott, P. Gibson, 2019, The Journal of allergy and clinical immunology.

Saturated fatty acids, obesity and the NLRP3 inflammasome in asthma

L. Wood, H. Scott, P. Gibson, 2018 .

Hypoxia‐inducible factor and bacterial infections in chronic obstructive pulmonary disease

S. Keely, E. Walters, S. Shukla, 2020, Respirology.

The Expression of IL-6, TNF-α, and MCP-1 in Respiratory Viral Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

P. Gibson, Jingtong Zheng, Junying Lu, 2017, Journal of immunology research.

The influence of early-life microbial exposures on long-term respiratory health.

S. Taylor, G. Rogers, J. Simpson, 2021, Paediatric Respiratory Reviews.

Induced sputum eosinophils and neutrophils and bronchiectasis severity in allergic bronchopulmonary aspergillosis.

P. Gibson, N. Saltos, P. Wark, 2000, The European respiratory journal.

Severity of Lung Function Impairment Drives Transcriptional Phenotypes of COPD and Relates to Immune and Metabolic Processes

P. Gibson, K. Baines, V. McDonald, 2023, International journal of chronic obstructive pulmonary disease.

Dampening of the respiratory cytokine storm is promoted by inhaled budesonide in patients with early COVID-19

D. V. Nicolau, L. Donnelly, M. Bafadhel, 2021, medRxiv.

Sputum mast cell subtypes relate to eosinophilia and corticosteroid response in asthma

G. Wang, L. Wood, P. Gibson, 2015, European Respiratory Journal.

Dysregulation of sputum columnar epithelial cells and products in distinct asthma phenotypes

L. Wood, P. Gibson, K. Baines, 2019, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Treatment burden, clinical outcomes, and comorbidities in COPD: an examination of the utility of medication regimen complexity index in COPD

P. Gibson, V. McDonald, P. Wark, 2017, International journal of chronic obstructive pulmonary disease.

Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma

K. Baines, L. Donnelly, A. Karlsson, 2019, Respiratory Research.

Is Alveolar Macrophage Phagocytic Dysfunction in Children With Protracted Bacterial Bronchitis a Forerunner to Bronchiectasis?

A. Chang, S. Hodge, G. Hodge, 2016, Chest.

Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment

C. Jenkins, A. James, G. Marks, 2021, Allergy.

Mepolizumab asthma treatment failure due to refractory airway eosinophilia, which responded to benralizumab

P. Wark, J. Simpson, J. Harrington, 2021, Respirology case reports.

Inflammatory phenotypes in stable and acute childhood asthma.

J. Simpson, F. Wang, Xiao-yan He, 2011, Paediatric respiratory reviews.

Differential cell counts using center-point networks achieves human-level accuracy and efficiency over segmentation

L. Garratt, D. Uminsky, J. Simpson, 2021, Scientific Reports.

The importance of clinical management problems in older people with COPD and asthma: do patients and physicians agree?

P. Gibson, V. McDonald, I. Higgins, 2011, Primary care respiratory journal : journal of the General Practice Airways Group.

Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma.

R. Scott, P. Gibson, J. Simpson, 2005, American journal of respiratory and critical care medicine.

Neutrophil Extracellular Traps are Increased in Severe Bronchiectasis and Reduced by Long-Term Azithromycin Treatment

F. Blasi, G. Rogers, O. Sibila, 2020 .

Mediators of neutrophil function in children with protracted bacterial bronchitis.

A. Chang, P. Gibson, K. Baines, 2014, Chest.

Cough, airway inflammation, and mild asthma exacerbation

I. Masters, A. Chang, P. Gibson, 2002, Archives of disease in childhood.

Airway β-Defensin-1 Protein Is Elevated in COPD and Severe Asthma

L. Wood, P. Gibson, K. Baines, 2015, Mediators of inflammation.

Immune Responses to Nontypeable Haemophilus Influenzae in Protracted Bacterial Bronchitis

A. Chang, S. Hodge, G. Hodge, 2015 .

Hemopexin: A Novel Anti-inflammatory Marker for Distinguishing COPD From Asthma

P. Gibson, V. McDonald, P. Wark, 2021, Allergy, asthma & immunology research.

Efficacy of azithromycin in severe asthma from the AMAZES randomised trial

C. Jenkins, A. James, G. Marks, 2019, ERJ Open Research.

IL-27 and asthma endotypes- Is there a connection

P. Foster, P. Gibson, K. Baines, 2017 .

Blood cytotoxic/inflammatory mediators in non‐eosinophilic asthma

A. James, S. Hodge, G. Hodge, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Sputum and Serum Periostin Levels Are Associated With, But Do Not Predict Sputum Eosinophil Proportion in Severe Asthma

C. Jenkins, A. James, S. Hodge, 2015 .

The role of exhaled nitric oxide and exhaled breath condensates in evaluating airway inflammation in asthma.

P. Wark, J. Simpson, 2008, Expert opinion on medical diagnostics.

The overlap syndrome of asthma and COPD: what are its features and how important is it?

P. Gibson, J. Simpson, 2009, Thorax.

Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease.

L. Wood, P. Gibson, V. McDonald, 2011, American journal of respiratory and critical care medicine.

Combined Haemophilus influenzae respiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma

P. Foster, P. Gibson, P. Hansbro, 2012, Thorax.

Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma

P. Gibson, P. Wark, S. Johnston, 2002, European Respiratory Journal.

Sputum ADAM8 expression is increased in severe asthma and COPD

K. Baines, V. McDonald, J. Simpson, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Impaired macrophage phagocytosis in non‐eosinophilic asthma

S. Hodge, J. Upham, J. Simpson, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD

K. Baines, V. McDonald, J. Simpson, 2016 .

Acute Asthma

P. Wark, J. Simpson, Alistair Cook, 2021, Reference Module in Biomedical Sciences.

COPD is characterized by increased detection of Haemophilus influenzae, Streptococcus pneumoniae and a deficiency of Bacillus species

P. Gibson, K. Baines, V. McDonald, 2016, Respirology.

Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma

L. Wood, P. Gibson, K. Baines, 2011, Thorax.

Longitudinal Changes in Clinical Outcomes in Older Patients with Asthma, COPD and Asthma-COPD Overlap Syndrome

P. Gibson, V. McDonald, J. Simpson, 2013, Respiration.