J. Ferrara

James Ferrara, Peter A Lachenbruch, Daniel Couriel, 2006, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Pathophysiology of graft-versus-host disease.

J. Ferrara, P. Reddy, 2006, Seminars in hematology.

J. Wingard, A. Tichelli, Stephanie J. Lee, 2006, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

The role of endotoxin and the innate immune response in the pathophysiology of acute graft versus host disease

K. Olkiewicz, J. Ferrara, K. Cooke, 2002, Journal of endotoxin research.

Graft-versus-host disease

E. Holler, J. Ferrara, J. Levine, 2009, The Lancet.

Graft-versus-host disease: the influence of type 1 and type 2 T cell cytokines.

J. Ferrara, W. Krenger, J. Ferrara, 1998, Transfusion medicine reviews.

The Pathophysiology of Graft‐Versus‐Host Disease

J. Ferrara, J. Antin, 2007 .

Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft-Versus-Host Disease

Thomas B. Sundberg, G. Glick, E. Gatza, 2011, Science Translational Medicine.

CD4+ beta islet cell-reactive T cell clones that suppress autoimmune diabetes in nonobese diabetic mice

J. Ferrara, J. Gold, L. Pan, 1995, The Journal of experimental medicine.

Blood and Marrow Transplant Clinical Trials Network: progress since the State of the Science Symposium 2007.

J. Ferrara, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease.

R. Kuick, S. Mineishi, S. Emerson, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents.

P. Mauch, S. Hellman, S. Neben, 1993, Experimental hematology.

Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect.

M. V. D. van den Brink, B. Kappel, J. Ferrara, 2001, Blood.

Immunobiology of acute graft-versus-host disease.

J. Ferrara, P. Reddy, 2003, Blood reviews.

Cytokine dysregulation and acute graft-versus-host disease.

J. Ferrara, J. Antin, Joseph, 1992, Blood.

Interleukin-1 is a critical effector molecule during cytokine dysregulation in graft versus host disease to minor histocompatibility antigens.

D. Gilliland, J. Ferrara, S. Abhyankar, 1993, Transplantation.

Polarized type 2 alloreactive CD4+ and CD8+ donor T cells fail to induce experimental acute graft-versus-host disease.

J. Ferrara, W. Krenger, K. Snyder, 1995, Journal of immunology.

Interferon-gamma suppresses T-cell proliferation to mitogen via the nitric oxide pathway during experimental acute graft-versus-host disease.

J. Ferrara, J. Delmonte, W. Krenger, 1996, Blood.

Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines.

J. Crawford, G. Hill, J. Ferrara, 1997, Blood.

Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.

J. Crawford, G. Hill, J. Keith, 1998, The Journal of clinical investigation.

Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease.

J. Crawford, G. Hill, D. Bungard, 1998, The Journal of clinical investigation.

Role of CXCR3-induced donor T-cell migration in acute GVHD.

S. Clouthier, U. Duffner, J. Ferrara, 2003, Experimental hematology.

Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect.

C. Dinarello, J. Ferrara, Y. Maeda, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Critical role of host γδ T cells in experimental acute graft-versus-host disease

J. Ferrara, Y. Maeda, D. Bishop, 2005 .

Critical role of host gammadelta T cells in experimental acute graft-versus-host disease.

J. Ferrara, Y. Maeda, D. Bishop, 2005, Blood.

A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responses

R. Korngold, J. Ferrara, Y. Maeda, 2005, Nature Medicine.

Essential Role for the P55 Tumor Necrosis Factor Receptor in Regulating Hematopoiesis at a Stem Cell Level

S. Lazo-Kallanian, G. Hill, J. Ferrara, 1999, The Journal of experimental medicine.

Looking toward the future: an individualized approach to allogeneic transplantation

J. Ferrara, C. Byersdorfer, 2013 .

IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation.

M. V. D. van den Brink, G. Hill, J. Ferrara, 1999, The Journal of clinical investigation.

232: A critical role of CD100 in allogeneic immune responses

G. Luker, A. Kumanogoh, J. Ferrara, 2007 .

A novel role for the semaphorin Sema4D in the induction of allo-responses.

G. Luker, A. Kumanogoh, C. Rogers, 2007, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Phase I/II Trial of a Combination of Anti-CD3/CD7 Immunotoxins for Steroid-Refractory Acute Graft-versus-Host Disease.

M. Netea, J. Inthout, R. Masereeuw, 2019, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

CD11c+CD86+ cells with direct and indirect antigen-presenting function Allogeneic T cells induce rapid CD34+ cell differentiation into

N. Mahmud, R. Hoffman, D. Mahmud, 2013 .

Allogeneic T cells induce rapid CD34+ cell differentiation into CD11c+CD86+ cells with direct and indirect antigen-presenting function.

N. Mahmud, R. Hoffman, D. Mahmud, 2006, Blood.

Therapeutic targets and emerging treatment options in gastrointestinal acute graft-versus-host disease

J. Ferrara, J. Levine, A. Renteria, 2016, Expert opinion on orphan drugs.

Prognostic implications of declining plasma gelsolin levels after allogeneic stem cell transplantation.

T. Stossel, J. Ferrara, M. Dinubile, 2002, Blood.

Pathogenesis and management of graft-versus-host disease.

S. Choi, J. Ferrara, J. Levine, 2010, Immunology and allergy clinics of North America.

Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation

Robin R. Shields-Cutler, D. Longo, D. Knights, 2020, Science Translational Medicine.

Housing Deadline for Tandem BMT Meetings

J. Vose, J. Wingard, R. Negrin, 2002 .

Late tissue-specific toxicity of total body irradiation and busulfan in a murine bone marrow transplant model.

B. Yeap, P. Mauch, S. Hellman, 1989, International journal of radiation oncology, biology, physics.

A refined risk score for acute GVHD that predicts response to initial therapy, survival and transplant-related mortality

M. Robin, M. Pasquini, Richard J. Jones, 2015 .

Donor leukocyte infusion from immunized donors increases tumor vaccine efficacy after allogeneic bone marrow transplantation.

G. Dranoff, J. Ferrara, Chen Liu, 2002, Cancer research.

Reduced-intensity allogeneic hematopoietic stem cell transplantation for acute leukemias: ‘what is the best recipe?’

S. Mineishi, A. Kassim, J. Ferrara, 2005, Bone Marrow Transplantation.

The impact of soluble tumor necrosis factor receptor etanercept on the treatment of idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation.

T. Braun, E. White, G. Yanik, 2008, Blood.

Pathophysiologic mechanisms of acute graft-vs.-host disease.

N. Chao, J. Ferrara, R. Levy, 1999, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Pretransplant chemotherapy reduces inflammatory cytokine production and acute graft-versus-host disease after allogeneic bone marrow transplantation.

G. Hill, D. Bungard, J. Ferrara, 1999, Transplantation.

Pilot study of iodine-131-metaiodobenzylguanidine in combination with myeloablative chemotherapy and autologous stem-cell support for the treatment of neuroblastoma.

K. Matthay, G. Yanik, R. Hutchinson, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes.

Shaun Parsons, E. Guinan, P. Mauch, 1997, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Proteomic patterns predict acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

A. Ganser, A. Zander, E. Schiffer, 2007, Blood.

Comment on Pula et al , page 4035 Uncovering the dark side of PKC

J. Ferrara, 2006 .

Biomarkers in acute graft-versus-host disease: new insights

J. Ferrara, J. Levine, Hrishikesh K. Srinagesh, 2019, Therapeutic advances in hematology.

Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies.

R. Macklis, E. Guinan, D. Golan, 1991, Blood.

Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease.

R. Thompson, P. McCarthy, S. Neben, 1991, Blood.

The p55 TNF-α Receptor Plays a Critical Role in T Cell Alloreactivity1

G. Hill, J. Ferrara, V. I. Rebel, 2000, The Journal of Immunology.

The p 55 TNF-a Receptor Plays a Critical Role in T Cell Alloreactivity 1

G. Hill, J. Ferrara, V. I. Rebel, 1999 .

Biological characteristics of an immunoregulatory activity secreted by an autoreactive CD4+ T cell clone that suppresses autoimmune diabetes in non-obese diabetic mice.

K. Myrick, J. Ferrara, L. Pan, 1996, International immunology.

Acute graft-versus-host disease biomarkers measured during therapy can predict treatment outcomes: a Blood and Marrow Transplant Clinical Trials Network study.

J. Bolaños-Meade, Juan Wu, S. Paczesny, 2012, Blood.

Monoclonal antibody and receptor antagonist therapy for GVHD.

E. Holler, B. Blazar, J. Ferrara, 1999, Cancer treatment and research.

CD8+ T cells activated during the course of murine acute myelogenous leukemia elicit therapeutic responses to late B7 vaccines after cytoreductive treatment.

H. Weinstein, J. Ferrara, W. Krenger, 1997, Blood.

Effector T cells require fatty acid metabolism during murine graft-versus-host disease.

G. Glick, V. Tkachev, J. Ferrara, 2013, Blood.

Extracorporeal photopheresis reverses experimental graft-versus-host disease through regulatory T cells.

E. Gatza, C. Rogers, S. Clouthier, 2008, Blood.

Low Paneth cell numbers at onset of gastrointestinal graft-versus-host disease identify patients at high risk for nonrelapse mortality.

T. Braun, J. Greenson, E. Holler, 2013, Blood.

Advances in predicting acute GVHD

J. Ferrara, J. Levine, Andrew C. Harris, 2013, British journal of haematology.

Initiate Acute Graft-versus-Host Disease Host Dendritic Cells Alone Are Sufficient to

U. Duffner, J. Ferrara, Y. Maeda, 2004 .

Host Dendritic Cells Alone Are Sufficient to Initiate Acute Graft-versus-Host Disease1

U. Duffner, J. Ferrara, Y. Maeda, 2004, The Journal of Immunology.

Flt 3 ligand therapy for recipients of allogeneic bone marrow transplants expands host CD 8 a 1 dendritic cells and reduces experimental acute graft-versus-host disease

J. Ferrara, P. Reddy, Chen Liu, 2002 .

Flt3 ligand therapy for recipients of allogeneic bone marrow transplants expands host CD8 alpha(+) dendritic cells and reduces experimental acute graft-versus-host disease.

J. Ferrara, P. Reddy, Chen Liu, 2002, Blood.

T cell receptor (β chain) transgenic mice have selective deficits in γδ T cell subpopulations

J. Seidman, D. Fruman, I. Orme, 1994 .

A delicate balance: tweaking IL-2 immunotherapy

T. Malek, J. Ferrara, 2012, Nature Medicine.

Differential roles of IL-1 and TNF-α on graft-versus-host disease and graft versus leukemia

J. Crawford, G. Hill, J. Ferrara, 1999 .

Mouse models of graft-versus-host disease

J. Ferrara, P. Reddy, 2009 .

The Pathophysiology of Acute Graft-versus-Host Disease

J. Ferrara, T. Teshima, K. Cooke, 2003, International journal of hematology.

Dysregulation of cytokines during graft-versus-host disease.

J. Ferrara, W. Krenger, 1996, Journal of hematotherapy.

SHORT COMMUNICATION Relationship of the Genes for Chediak-Higashi Syndrome (Beige) and the T-Cell Receptor y Chain in Mouse and Man

A. Fauci, B. Taylor, R. Leavitt, 1987 .

Tumor cell vaccine elicits potent antitumor immunity after allogeneic T-cell-depleted bone marrow transplantation.

G. Dranoff, G. Hill, S. Gillessen, 2001, Cancer research.

Immunotherapy through T-cell receptor gene transfer induces severe graft-versus-host disease.

S. Paczesny, J. Ferrara, P. Reddy, 2010, Immunotherapy.

Acute graft-versus-host disease does not require alloantigen expression on host epithelium

J. Ferrara, P. Reddy, Chen Liu, 2002, Nature Medicine.

Anaplerotic Metabolism of Alloreactive T Cells Provides a Metabolic Approach To Treat Graft-Versus-Host Disease

L. Boros, C. Lyssiotis, R. Rossignol, 2014, The Journal of Pharmacology and Experimental Therapeutics.

West Nile virus encephalitis causing fatal CNS toxicity after hematopoietic stem cell transplantation

J. Ferrara, V. Ratanatharathorn, P. Reddy, 2004, Bone Marrow Transplantation.

T Cell-Mediated Rejection of Human CD34+ Cells Is Prevented by Costimulatory Blockade in a Xenograft Model.

N. Mahmud, D. Mahmud, J. Ferrara, 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Pilot trial on the use of etanercept and methylprednisolone as primary treatment for acute graft-versus-host disease.

T. Braun, M. Becker, G. Yanik, 2005, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Induction of graft-versus-host disease as immunotherapy for relapsed chronic myeloid leukemia.

D. Porter, J. Ferrara, J. Antin, 1994, The New England journal of medicine.

Tumor Necrosis Factor – a Production to Lipopolysaccharide Stimulation by Donor Cells Predicts the Severity of Experimental Acute Graft-Versus-Host Disease

J. Crawford, G. Hill, D. Bungard, 1998 .

hematopoietic stem cell transplantation treatment of idiopathic pneumonia syndrome after allogeneic The impact of soluble tumor necrosis factor receptor etanercept on the

T. Braun, E. White, G. Yanik, 2011 .

Biomarkers for Chronic Graft-versus-Host isease : National Institutes of Health Consensus evelopment Project on Criteria for Clinical Trials n Chronic Graft-versus-Host Disease : III . Biomarker orking Group Report

P. Lachenbruch, D. Miklos, E. Holler, 2006 .

Acute cutaneous graft-versus-host disease to minor histocompatibility antigens in a murine model. Evidence that large granular lymphocytes are effector cells in the immune response.

W. Hancock, G. Murphy, D. Messadi, 1986, Laboratory investigation; a journal of technical methods and pathology.

MAGIC biomarkers of acute graft-versus-host disease: Biology and clinical application.

J. Ferrara, Hrishikesh K. Srinagesh, H. Srinagesh, 2019, Best practice & research. Clinical haematology.

Plasma elevations of tumor necrosis factor-receptor-1 at day 7 postallogeneic transplant correlate with graft-versus-host disease severity and overall survival in pediatric patients.

T. Braun, S. Choi, S. Paczesny, 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Developmental regulation of erythropoiesis by hematopoietic growth factors: analysis on populations of BFU-E from bone marrow, peripheral blood, and fetal liver

S. Emerson, J. Ferrara, J. Greenstein, 1989 .

Developmental regulation of erythropoiesis by hematopoietic growth factors: analysis on populations of BFU-E from bone marrow, peripheral blood, and fetal liver.

S. Emerson, J. Ferrara, J. Greenstein, 1989, Blood.

Paradoxical effects of interleukin-18 on the severity of acute graft-versus-host disease mediated by CD4+ and CD8+ T-cell subsets after experimental allogeneic bone marrow transplantation.

S. Clouthier, J. Ferrara, C. Min, 2004, Blood.

Paradoxical effects of interleukin-18 on the severity of acute graft-versus-host disease mediated by CD4 (cid:1) and CD8 (cid:1) T-cell subsets after experimental allogeneic bone marrow transplantation

S. Clouthier, J. Ferrara, C. Min, 2004 .

Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity.

M. V. D. van den Brink, J. Ferrara, S. Burakoff, 2000, Transplantation.

ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death.

T. Braun, S. Hanash, J. Ritz, 2013, The New England journal of medicine.

Etanercept (Enbrel) administration for idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation.

B. Hellerstedt, G. Yanik, R. Hutchinson, 2002, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Understanding the alloresponse: new approaches to graft-versus-host disease prevention.

J. Ferrara, T. Teshima, 2002, Seminars in hematology.

Biodistribution studies of anti-Thy 1.2 IgM immunoconjugates: implications for radioimmunotherapy.

R. Macklis, A. Kassis, B. Kinsey, 1988, International journal of radiation oncology, biology, physics.

Double dose-intensive chemotherapy with autologous stem cell support for relapsed and refractory testicular cancer: the University of Michigan experience and literature review

T. Braun, J. Ferrara, E. R. Broun, 2001, Bone Marrow Transplantation.

Evidence that anti-asialo GM1 in vivo improves engraftment of T cell-depleted bone marrow in hybrid recipients.

J. Ferrara, S. Burakoff, K. Crosier, 1990, Transplantation.

Cellular and cytokine effectors of acute graft versus host disease

J. Ferrara, 2002, International journal of hematology.

Pathogenic mechanisms of Acute Graft versus Host Disease

J. Ferrara, 2002 .

Hyporesponsiveness of Donor Cells to Lipopolysaccharide Stimulation Reduces the Severity of Experimental Idiopathic Pneumonia Syndrome: Potential Role for a Gut-Lung Axis of Inflammation1

J. Crawford, L. Kobzik, G. Hill, 2000, The Journal of Immunology.

Gut-Lung Axis of Inflammation Pneumonia Syndrome : Potential Role for a Severity of Experimental Idiopathic Lipopolysaccharide Stimulation Reduces the Hyporesponsiveness of Donor Cells to Brewer and

J. Crawford, G. Hill, T. Martin, 2000 .

Role of interleukin-18 in acute graft-vs-host disease.

J. Ferrara, P. Reddy, 2003, The Journal of laboratory and clinical medicine.

The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity.

G. Hill, J. Ferrara, V. I. Rebel, 2000, Journal of immunology.

EBMT—NIH—CIBMTR Task Force position statement on standardized terminology & guidance for graft-versus-host disease assessment

E. Holler, H. Greinix, Stephanie J. Lee, 2018, Bone Marrow Transplantation.

International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium.

D. Porter, F. Locatelli, E. Holler, 2016, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Have we made progress in the treatment of GVHD?

J. Ferrara, J. Levine, Andrew C. Harris, 2012, Best practice & research. Clinical haematology.

Long-term follow-up of a phase I/II randomized, placebo-controlled trial of palifermin to prevent graft-versus-host disease (GVHD) after related donor allogeneic hematopoietic cell transplantation (HCT).

D. Weisdorf, B. Blazar, J. Ferrara, 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Phase 1/2 randomized, placebo-control trial of palifermin to prevent graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT).

T. Braun, D. Weisdorf, B. Blazar, 2006, Blood.

Adoptive immunotherapy with donor mononuclear cell infusions to treat relapse of acute leukemia or myelodysplasia after allogeneic bone marrow transplantation.

D. Porter, J. Ferrara, J. Antin, 1996, Bone marrow transplantation.

MAGIC biomarkers predict long-term outcomes for steroid-resistant acute GVHD.

N. Kröger, E. Holler, Y. Efebera, 2018, Blood.

An early-biomarker algorithm predicts lethal graft-versus-host disease and survival.

N. Kröger, F. Locatelli, E. Holler, 2017, JCI insight.

Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines.

G. Dranoff, B. Bierer, H. Weinstein, 1998, Blood.

Acute Graft Versus Host Disease

J. Ferrara, J. Levine, A. Renteria, 2019, Mount Sinai Expert Guides.

Development of a biomarker scoring system for use in graft-versus-host disease.

J. Ferrara, J. Levine, A. Renteria, 2016, Biomarkers in medicine.

A prognostic score for acute graft-versus-host disease based on biomarkers: a multicentre study.

T. Braun, J. Bolaños-Meade, E. Holler, 2015, The Lancet. Haematology.

Assessment of systemic and gastrointestinal tissue damage biomarkers for GVHD risk stratification

E. Holler, Z. DeFilipp, Jung-Yi Lin, 2022, Blood advances.

Improved accuracy of acute graft-versus-host disease staging among multiple centers.

Y. Efebera, S. Devine, W. Hogan, 2014, Best practice & research. Clinical haematology.

Frequency of CD4 + CD25 hi FOXP3 + Regulatory T Cells Has Diagnostic and Prognostic Value as a Biomarker for Acute Graft-Versus-Host Disease.

T. Braun, S. Mineishi, S. Choi, 2009 .

Assessing the potential role of photopheresis in hematopoietic stem cell transplant

M. Albert, E. Holler, H. Greinix, 2006, Bone Marrow Transplantation.

Late acute graft-versus-host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors.

W. Wood, B. Storer, J. Pidala, 2016, Blood.

Allogeneic Hematopoietic Stem Cell Transplantation with Clofarabine/Busulfan × 4 (CloBu4) Conditioning Exhibits Significant Anti-Tumor Activity In Non - Remission Hematologic Malignancies, Especially In AML

S. Mineishi, S. Choi, G. Yanik, 2010 .

Acute GVHD: New approaches to clinical trial monitoring.

J. Ferrara, J. Levine, Nikolaos Spyrou, 2022, Best practice & research. Clinical haematology.

The role of cytokines in acute graft-versus-host disease.

G. Hill, J. Ferrara, W. Krenger, 1997, Cytokines, cellular & molecular therapy.

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.

Simon C Watkins, T. Junt, S. Nakae, 2015, Blood.

A Phase I/II Randomized, Placebo-Control Trial of Palifermin to Prevent Graft-Versus- Host Disease (GVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Running head: Palifermin to prevent GVHD

T. Braun, D. Weisdorf, B. Blazar, 2006 .

Both perforin and Fas ligand are required for the regulation of alloreactive CD8+ T cells during acute graft-versus-host disease.

S. Clouthier, J. Ferrara, R. Levy, 2005, Blood.

CD4 + /3 Islet Cell-reactive T Cell Clones That Suppress Autoimmune Diabetes in Nonobese Diabetic Mice By Irfan Akhtar,* Jennifer p. Gold,* Lu-Ying Pan,*

James I. Kim, J. Ferrara, Xiao-Dong Yang, 1995 .

Metagenomic analysis of the stool microbiome in patients receiving allogeneic SCT: Loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal GvHD

R. Spang, P. Oefner, E. Holler, 2014 .

Chronic graft-versus-host disease after granulocyte colony-stimulating factor-mobilized allogeneic stem cell transplantation: the role of donor T-cell dose and differentiation.

G. Hill, A. Clouston, K. MacDonald, 2004, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Immunobiology of acute graft-versus-host disease Immunobiology of acute graft-versus-host disease

J. Ferrara, P. Reddy, 2003 .

Pathogenesis and prevention of graft-versus-host disease

J. Ferrara, T. Teshima, 2001 .

Cytokine Dysregulation in Acute Graft-versus-Host Disease.

G. Hill, J. Ferrara, W. Krenger, 1997, Hematology.

Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease.

J. Crawford, S. Sonis, J. Ferrara, 1996, Transplantation.

EFFECTS OF EXOGENOUS INTERLEUKIN‐10 IN A MURINE MODEL OF GRAFT‐VERSUS-HOST DISEASE TO MINOR HISTOCOMPATIBILITY ANTIGENS

J. Ferrara, W. Krenger, K. Snyder, 1994, Transplantation.

Keratinocyte Growth Factor Separates Graft-Versus-Leukemia Effects From Graft-Versus-Host Disease

J. Crawford, G. Hill, J. Ferrara, 1999 .

Keratinocyte growth factor separates graft-versus-leukemia effects from graft-versus-host disease.

J. Crawford, G. Hill, J. Ferrara, 1999, Blood.

Cytokine storm of graft-versus-host disease: a critical effector role for interleukin-1.

J. Ferrara, S. Abhyankar, D. Gilliland, 1993, Transplantation proceedings.

Syngeneic graft-vs-host disease.

J. Ferrara, 1987, Archives of dermatology.

Cytokines and the regulation of tolerance.

J. Ferrara, 2000, The Journal of clinical investigation.

Antigen-induced unresponsiveness results in altered T cell signaling.

T. Strom, H. Irie, Yongsheng Li, 1999, Journal of immunology.

Immunodeficiency in graft-versus-host disease. I. Mechanism of immune suppression.

A. Abbas, J. Ferrara, S. Burakoff, 1988, Journal of immunology.

Etanercept plus methylprednisolone as initial therapy for acute graft-versus-host disease.

T. Braun, S. Mineishi, S. Choi, 2007, Blood.

Treatment of chronic graft-versus-host disease with anti-CD20 chimeric monoclonal antibody.

M. Becker, J. Ferrara, V. Ratanatharathorn, 2003, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Anti-CD20 Chimeric Monoclonal Antibody Treatment of Refractory Immune-Mediated Thrombocytopenia in a Patient with Chronic Graft-versus-Host Disease

G. Yanik, J. Ferrara, V. Ratanatharathorn, 2000, Annals of Internal Medicine.

Tacrolimus (FK506) and methotrexate as prophylaxis for acute graft-versus-host disease in pediatric allogeneic stem cell transplantation

G. Yanik, R. Hutchinson, J. Ferrara, 2000, Bone Marrow Transplantation.

Reply to “Is alloantigen expression by host epithelium required for acute graft-versus-host disease?”

J. Ferrara, T. Teshima, 2003, Nature Medicine.

Acute graft versus host disease: pathophysiology, risk factors, and prevention strategies.

G. Yanik, J. Ferrara, 2005, Clinical advances in hematology & oncology : H&O.

Granulocyte colony-stimulating factor-mobilized allogeneic stem cell transplantation maintains graft-versus-leukemia effects through a perforin-dependent pathway while preventing graft-versus-host disease.

G. Hill, D. Bungard, J. Ferrara, 1999, Blood.

RAPID COMMUNICATION Granulocyte Colony-Stimulating Factor–Mobilized Allogeneic Stem Cell Transplantation Maintains Graft-Versus-Leukemia Effects Through a Perforin-Dependent Pathway While Preventing Graft-Versus-Host Disease

G. Hill, D. Bungard, J. Ferrara, 2022 .

Novel strategies for the treatment and diagnosis of graft-versus-host-disease.

J. Ferrara, 2007, Best practice & research. Clinical haematology.

Prevention of transfusion-associated graft-versus-host disease by photochemical treatment.

L. Corash, J. Ferrara, L. Lin, 1999, Blood.

Cytokine cascades in acute graft-versus-host disease.

G. Hill, J. Ferrara, W. Krenger, 1997, Transplantation.

Graft-versus-host disease in the 21st century: new perspectives on an old problem.

J. Ferrara, J. Levine, 2006, Seminars in hematology.

TNF-inhibition with etanercept for graft-versus-host disease prevention in high-risk HCT: lower TNFR1 levels correlate with better outcomes.

Scott E. Smith, T. Braun, D. Hanauer, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Three Biomarker Panel at Day 7 and 14 Can Predict Development of Grade II-IV Acute Graft-Versus-Host Disease

T. Braun, S. Hanash, S. Mineishi, 2010 .

Allogeneic Stem Cell Transplantation Prognostic Implications of Declining Plasma Gelsolin Levels After

T. Stossel, J. Ferrara, M. Dinubile, 2002 .

Combination Therapy for Graft-versus-Host Disease Prophylaxis with Etanercept and Extracorporeal Photopheresis: Results of a Phase II Clinical Trial.

T. Braun, S. Choi, D. Couriel, 2016, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Graft vs. Host Disease, Third Edition

J. Ferrara, H. Deeg, K. Cooke, 2004 .

A Biomarker-Based Grading System At Onset Of GvHD Predicts NRM Better Than The Modified Glucksberg Grading System

T. Braun, J. Magenau, J. Ferrara, 2013 .

Effect of graft-versus-host disease on hematopoiesis after bone marrow transplantation in mice.

J. Crawford, J. Ferrara, J. Wimperis, 1991, Blood.

The use of laparoscopic liver biopsies in pediatric patients with hepatic dysfunction following allogeneic hematopoietic stem cell transplantation

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