M. Walther

发表

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

L. Coin, D. Conway, T. Otto, 2017, Science Translational Medicine.

Distinct Roles for FOXP3+ and FOXP3− CD4+ T Cells in Regulating Cellular Immunity to Uncomplicated and Severe Plasmodium falciparum Malaria

D. Conway, E. Riley, Ian H Cheeseman, 2009, PLoS pathogens.

Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial.

Erin E Gabriel, Michael P Fay, Sumana Chakravarty, 2017, The Lancet. Infectious diseases.

Quantitative detection of Plasmodium falciparum DNA in saliva, blood, and urine.

D. Conway, D. Nwakanma, M. Walther, 2009, The Journal of infectious diseases.

A Decline in the Incidence of Invasive Non-Typhoidal Salmonella Infection in the Gambia Temporally Associated with a Decline in Malaria Infection

D. Conway, K. Bojang, R. Adegbola, 2010, PloS one.

Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection.

R. Sinden, P. Bejon, E. Riley, 2005, Immunity.

Calculation of liver-to-blood inocula, parasite growth rates, and preerythrocytic vaccine efficacy, from serial quantitative polymerase chain reaction studies of volunteers challenged with malaria sporozoites.

D. Webster, T. Peto, P. Bejon, 2005, The Journal of infectious diseases.

Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis

D. Conway, O. Billker, A. Cunnington, 2015, PLoS pathogens.

Killer-cell immunoglobulin-like receptors and malaria caused by Plasmodium falciparum in The Gambia

D. Conway, M. Jallow, P. Aka, 2012, Tissue antigens.

Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate

D. Conway, K. Tracey, P. Kaye, 2010, PloS one.

The Breadth, but Not the Magnitude, of Circulating Memory B Cell Responses to P. falciparum Increases with Age/Exposure in an Area of Low Transmission

D. Conway, E. Riley, E. Remarque, 2011, PloS one.

Early Gamma Interferon and Interleukin-2 Responses to Vaccination Predict the Late Resting Memory in Malaria-Naïve and Malaria-Exposed Individuals

D. Carucci, K. Marsh, T. Lang, 2006, Infection and Immunity.

Safety, Immunogenicity, and Efficacy of Prime-Boost Immunization with Recombinant Poxvirus FP9 and Modified Vaccinia Virus Ankara Encoding the Full-Length Plasmodium falciparum Circumsporozoite Protein

R. Sinden, A. Hill, G. Butcher, 2006, Infection and Immunity.

Innate Immune Responses to Human Malaria: Heterogeneous Cytokine Responses to Blood-Stage Plasmodium falciparum Correlate with Parasitological and Clinical Outcomes1

R. Sinden, P. Bejon, E. Riley, 2006, The Journal of Immunology.

Innate Immune Responses to Human Malaria: Heterogeneous Cytokine Responses to Blood-Stage Plasmodium falciparum Correlate with Parasitological and Clinical Outcomes

P. Bejon, E. Riley, S. Gilbert, 2006 .

Correlate with Parasitological and Clinical Plasmodium falciparum to Blood-Stage Malaria : Heterogeneous Cytokine Responses Innate Immune Responses to Human Sinden

P. Bejon, E. Riley, A. Hill, 2006 .

What does it take to control malaria?

M. Walther, B. Walther, 2007, Annals of tropical medicine and parasitology.

Prolonged Neutrophil Dysfunction after Plasmodium falciparum Malaria Is Related to Hemolysis and Heme Oxygenase-1 Induction

E. Riley, A. Cunnington, S. Correa, 2012, The Journal of Immunology.

Hemolysis and Heme Oxygenase-1 Induction Malaria Is Related to Plasmodium falciparum Prolonged Neutrophil Dysfunction after

E. Riley, A. Cunnington, S. Correa, 2012 .

Building better T‐cell‐inducing malaria vaccines

S. Todryk, M. Walther, 2005, Immunology.

Estimating parasite load dynamics to reveal novel resistance mechanisms to human malaria

L. Coin, D. Conway, A. Ghani, 2018, bioRxiv.

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

Q. Bassat, N. Anstey, A. Ghani, 2020, PLoS medicine.

Distinct Roles for FOXP 3 + and FOXP 3 2 CD 4 + T Cells in Regulating Cellular Immunity to Uncomplicated and Severe Plasmodium falciparum Malaria

D. Conway, E. Riley, E. Lawrence, 2017 .

Comparison of parasite sequestration in uncomplicated and severe childhood Plasmodium falciparum malaria☆

E. Riley, A. Cunnington, M. Bretscher, 2013, The Journal of infection.

Clinical Features of Severe Malaria Associated with Death: A 13-Year Observational Study in The Gambia

D. Kwiatkowski, D. Conway, M. Jallow, 2012, PloS one.

Revisiting the Effect of Acute P. falciparum Malaria on Epstein-Barr Virus: Host Balance in the Setting of Reduced Malaria Endemicity

S. Rowland-Jones, H. Whittle, A. Rickinson, 2012, PloS one.

Safety of recombinant fowlpox strain FP9 and modified vaccinia virus Ankara vaccines against liver-stage P. falciparum malaria in non-immune volunteers.

D. Webster, T. Peto, A. Hill, 2006, Vaccine.

Diagnosis of human filariases (except onchocerciasis).

R. Muller, M. Walther, 2003, Advances in parasitology.

Erythrocyte invasion and merozoite ligand gene expression in severe and mild Plasmodium falciparum malaria.

D. Conway, M. Walther, A. Amambua-Ngwa, 2010, The Journal of infectious diseases.

Epigenetic dysregulation of virulence gene expression in severe Plasmodium falciparum malaria.

C. Huttenhower, D. Conway, C. Buckee, 2012, The Journal of infectious diseases.

Induction of Strain-Transcending Antibodies Against Group A PfEMP1 Surface Antigens from Virulent Malaria Parasites

D. Conway, O. Doumbo, J. Rowe, 2012, PLoS pathogens.

Prescribing practice for malaria following introduction of artemether-lumefantrine in an urban area with declining endemicity in West Africa

D. Conway, D. Schellenberg, M. Walther, 2010, Malaria Journal.

Continued Decline of Malaria in The Gambia with Implications for Elimination

D. Conway, K. Bojang, D. Nwakanma, 2010, PloS one.

A DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccine Encoding Thrombospondin-Related Adhesion Protein but Not Circumsporozoite Protein Partially Protects Healthy Malaria-Naive Adults against Plasmodium falciparum Sporozoite Challenge

D. Webster, D. Carucci, R. Sinden, 2006, Infection and Immunity.

Multiple functions of human T cells generated by experimental malaria challenge

P. Bejon, A. Hill, S. Todryk, 2009, European journal of immunology.

Regulatory T cells in malaria--friend or foe?

E. Riley, M. Walther, O. Finney, 2010, Trends in immunology.

Evaluating the frequency of bacterial co-infections in children recruited into a malaria pathogenesis study in The Gambia, West Africa using molecular methods.

M. Walther, S. Burr, G. Morris, 2012, Molecular and cellular probes.

HMOX1 Gene Promoter Alleles and High HO-1 Levels Are Associated with Severe Malaria in Gambian Children

Scott M. Williams, G. Sirugo, D. Conway, 2012, PLoS pathogens.

Bioactive TGF-beta levels can be preserved in plasma samples collected into heparin but not EDTA.

D. Jeffries, M. Walther, B. Walther, 2009, Cytokine.

Phenotypic analysis of human peripheral blood regulatory T cells (CD4+FOXP3+CD127lo/–) ex vivo and after in vitro restimulation with malaria antigens

E. Riley, M. Walther, O. Finney, 2009, European journal of immunology.

Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission

D. Conway, E. Riley, D. Nwakanma, 2009, European journal of immunology.

Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720.

D. Webster, R. Sinden, A. Schmidt, 2005, Vaccine.

Piecing Together the Puzzle of Severe Malaria

E. Riley, A. Cunnington, M. Walther, 2013, Science Translational Medicine.

A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS.

D. Webster, R. Sinden, P. Bejon, 2006, Vaccine.

Comparison of surveillance methods applied to a situation of low malaria prevalence at rural sites in The Gambia and Guinea Bissau

D. Conway, C. Drakeley, P. Corran, 2009, Malaria Journal.

G6PD A- deficiency and severe malaria in The Gambia: heterozygote advantage and possible homozygote disadvantage.

Scott M. Williams, G. Sirugo, I. Predazzi, 2014, The American journal of tropical medicine and hygiene.

Freeze-thaw lysates of Plasmodium falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells

E. Riley, E. Lawrence, M. Walther, 2012, European journal of immunology.

Comparison of Modeling Methods to Determine Liver-to-blood Inocula and Parasite Multiplication Rates During Controlled Human Malaria Infection

D. Webster, P. Bejon, A. Hill, 2013, The Journal of infectious diseases.

Stuck in a rut? Reconsidering the role of parasite sequestration in severe malaria syndromes.

E. Riley, A. Cunnington, M. Walther, 2013, Trends in parasitology.

Complement Factor H Levels Associate With Plasmodium falciparum Malaria Susceptibility and Severity

D. Conway, S. Anderson, M. Levin, 2018, Open forum infectious diseases.

PfHPRT: a new biomarker candidate of acute Plasmodium falciparum infection.

D. Conway, R. Fischer, B. Kessler, 2013, Journal of proteome research.

Advances in vaccine development against the pre-erythrocytic stage of Plasmodium falciparum malaria

M. Walther, 2006, Expert review of vaccines.

Microvascular dysfunction in severe Plasmodium falciparum Malaria.

E. Riley, A. Cunnington, M. Walther, 2013, The Journal of infectious diseases.

Predictors of hyperlactataemia among children presenting with malaria in a low transmission area in The Gambia

K. Bhaskaran, M. Walther, A. Ebonyi, 2013, Malaria Journal.

Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions

L. Coin, D. Conway, A. Ghani, 2019, Nature Microbiology.

Modelling pathogen load dynamics to elucidate mechanistic determinants 1 of host- Plasmodium falciparum interactions 2

L. Coin, D. Conway, A. Ghani, 2019 .

Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature.

Colin G Fink, L. Coin, S. Anderson, 2023, Med.