J. Eckstein

发表

INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450

B. Ring, S. Wrighton, J. Rehmel, 2006, Drug Metabolism and Disposition.

Simultaneous profiling of multiple neurochemical pathways from a single cerebrospinal fluid sample using GC/MS/MS with electron capture detection.

J. Eckstein, Gina M. Ammerman, Jessica M. Reveles, 2008, Journal of mass spectrometry : JMS.

Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation.

M. Bard, M. Krieger, J. Eckstein, 1999, Proceedings of the National Academy of Sciences of the United States of America.

An assessment of udp-glucuronosyltransferase induction using primary human hepatocytes.

S. Wrighton, J. Eckstein, S. C. Kasper, 2004, Drug metabolism and disposition: the biological fate of chemicals.

N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a Novel Metabotropic Glutamate 2 Potentiator with Potential Anxiolytic/Antidepressant Properties: In Vivo Profiling Suggests a Link between Behavioral and Central Nervous System Neu

G. Marek, K. Perry, J. Witkin, 2011, Journal of Pharmacology and Experimental Therapeutics.

ffect of tadalafil on cytochrome P 450 A 4 – mediated clearance : Studies in vitro nd in vivo

J. Gillespie, S. Wrighton, M. Mitchell, 2004 .

COMPARATIVE METABOLIC CAPABILITIES OF CYP 3 A 4 , CYP 3 A 5 , AND CYP 3 A 7

B. Ring, S. Wrighton, S. Hall, 2002 .

Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans.

M. Bard, K. Barker, P. D. Rogers, 2004, The Journal of antimicrobial chemotherapy.

Ergosterol gene expression in wild-type and ergosterol-deficient mutants of Candida albicans.

M. Bard, J. Eckstein, C. Pierson, 2004, Medical mycology.

Candida albicans Sterol C-14 Reductase, Encoded by the ERG24 Gene, as a Potential Antifungal Target Site

M. Bard, N. Lees, J. Eckstein, 2002, Antimicrobial Agents and Chemotherapy.

Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase.

M. Bard, N. Lees, J. Eckstein, 2004, Medical Mycology.

Cloning and sequencing of the Candida albicans C-4 sterol methyl oxidase gene (ERG25) and expression of an ERG25 conditional lethal mutation in Saccharomyces cerevisiae

M. Bard, N. Lees, J. Eckstein, 2000, Lipids.

Identification of the human cytochromes p450 responsible for in vitro formation of R- and S-norfluoxetine.

S. Binkley, J. Gillespie, B. Ring, 2001, The Journal of pharmacology and experimental therapeutics.

Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.

B. Ring, S. Wrighton, S. Hall, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Sterol uptake in Candida glabrata: rescue of sterol auxotrophic strains.

M. Bard, N. Lees, J. Eckstein, 2005, Diagnostic microbiology and infectious disease.

Disruption of the Candida albicans CYB5 Gene Results in Increased Azole Sensitivity

M. Bard, N. Lees, J. Eckstein, 2004, Antimicrobial Agents and Chemotherapy.

Current applications of liquid chromatography/mass spectrometry in pharmaceutical discovery after a decade of innovation.

Bradley L Ackermann, A. Chaudhary, M. Berna, 2008, Annual review of analytical chemistry.

Determination of a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist (LY300164) and its N-acetyl metabolite in mouse, rat, dog, and monkey plasma using high-performance liquid chromatography with ultraviolet detection

J. Eckstein, S. Swanson, 1995 .

Analysis of glutamine, glutamate, pyroglutamate, and GABA in cerebrospinal fluid using ion pairing HPLC with positive electrospray LC/MS/MS

J. Eckstein, Gina M. Ammerman, Jessica M. Reveles, 2008, Journal of Neuroscience Methods.

Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.

M. Bard, A. Link, P. Espenshade, 2007, Cell metabolism.

Dap 1 / PGRMC 1 Binds and Regulates Cytochrome P 450 Enzymes

M. Bard, A. Link, P. Espenshade, 2022 .

Cumulative Mutations Affecting Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae Result in Synthetic Lethality That Is Suppressed by Alterations in Sphingolipid Profiles

Martin Bard, M. Bard, S. Sturley, 2006, Genetics.

Determination of dolasetron and its reduced metabolite in human plasma by GC-MS and LC.

T. Gillespie, J. Eckstein, J. Coutant, 1993, Journal of pharmaceutical and biomedical analysis.

A novel gene conserved from yeast to humans is involved in sterol biosynthesis.

M. Bard, J. Eckstein, R. Barbuch, 2001, Journal of lipid research.

Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules.

Bradley L Ackermann, J. Eckstein, B. Ackermann, 2012, Bioanalysis.

Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae.

M. Bard, B. Teske, S. Randall, 2008, Biochimica et biophysica acta.

Identification of the human cytochromes P450 responsible for atomoxetine metabolism.

J. Gillespie, B. Ring, S. Wrighton, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Effect of Tadalafil on Cytochrome P450 3A4–mediated Clearance: Studies in Vitro and in Vivo

J. Gillespie, B. Ring, S. Wrighton, 2005, Clinical pharmacology and therapeutics.

Effects of a novel mGlu2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid

R. Dean, K. Perry, D. McKinzie, 2012, Psychopharmacology.

Synthetically Lethal Interactions Involving Loss of the Yeast ERG24: The Sterol C-14 Reductase Gene

Martin Bard, M. Bard, J. Eckstein, 2007, Lipids.

Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans.

M. Bard, K. Barker, J. Eckstein, 2004, The Journal of antimicrobial chemotherapy.

Simultaneous profiling of multiple neurochemical pathways from a single cerebrospinal fluid sample using GC/MS/MS with electron capture detection.

J. Eckstein, Gina M. Ammerman, Jessica M. Reveles, 2008, Journal of mass spectrometry : JMS.

Effects of a novel mGlu2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid

R. Dean, K. Perry, D. McKinzie, 2011, Psychopharmacology.