Jin Jiang

发表

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

C. Chien, B. Wang, Qing Zhang, 2006, Developmental cell.

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system

Y. Xiong, Yun Zhao, Jin Jiang, 2017, PLoS biology.

Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway.

B. Wang, Jin Jiang, Yuhong Han, 2016, Developmental cell.

Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase

B. Wang, Chao Tong, Jin Jiang, 2016, PLoS biology.

Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activator

Jin Jiang, Shuangxi Li, Shuang Li, 2014, Proceedings of the National Academy of Sciences.

Hedgehog-Regulated Ubiquitination Controls Smoothened Trafficking and Cell Surface Expression in Drosophila

B. Wang, Jin Jiang, Shuang Li, 2012, PLoS biology.

Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened

J. Briscoe, J. Jia, N. Sasai, 2011, PLoS biology.

G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila.

B. Wang, Yun Zhao, Chao Tong, 2010, Genes & development.

Using immunoprecipitation to study protein-protein interactions in the Hedgehog-signaling pathway.

Chao Tong, Jin Jiang, 2007, Methods in molecular biology.

Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation.

J. Jia, Yajuan Liu, Jin Jiang, 2007, Genes & development.

Phosphorylation by Double-Time/CKIε and CKIα Targets Cubitus Interruptus for Slimb/β-TRCP-Mediated Proteolytic Processing

B. Wang, Chao Tong, J. Jia, 2005 .

Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail.

Chao Tong, J. Jia, Jin Jiang, 2003, Genes & development.

Protein kinase A and hedgehog signaling in drosophila limb development

G. Struhl, Jin Jiang, Gary Struhl, 1995, Cell.

Degrading Ci: who is Cul-pable?

Jin Jiang, 2002, Genes & development.

Hedgehog signaling in development and cancer.

Chi-Chung Hui, C. Hui, Jin Jiang, 2008, Developmental cell.

Multisite interaction with Sufu regulates Ci/Gli activity through distinct mechanisms in Hh signal transduction

Jin Jiang, Yuhong Han, Qing Shi, 2015, Proceedings of the National Academy of Sciences.

SCYL 1 BP 1 has Tumor-suppressive Functions in Human Lung Squamous Carcinoma Cells by Regulating Degradation of MDM 2

Jin Jiang, Zhi-Ping Yang, Yong-Hong Xie, 2014 .

SCYL1BP1 has tumor-suppressive functions in human lung squamous carcinoma cells by regulating degradation of MDM2.

Jin Jiang, Zhi-Ping Yang, Yong-Hong Xie, 2014, Asian Pacific journal of cancer prevention : APJCP.

Hippo signaling pathway and organ size control

Lei Zhang, Jin Jiang, Tao Yue, 2009, Fly.

CK1 in Developmental Signaling: Hedgehog and Wnt.

Jin Jiang, 2017, Current topics in developmental biology.

Regulation of Hh/Gli Signaling by Dual Ubiquitin Pathways

Jin Jiang, 2006, Cell cycle.

Phosphorylation by double-time/CKIepsilon and CKIalpha targets cubitus interruptus for Slimb/beta-TRCP-mediated proteolytic processing.

B. Wang, Chao Tong, J. Jia, 2005, Developmental cell.

Converse Conformational Control of Smoothened Activity by Structurally Related Small Molecules*

Shuo Lin, Song Li, James K. Chen, 2009, The Journal of Biological Chemistry.

Fem1b promotes ubiquitylation and suppresses transcriptional activity of Gli1.

A. S. Gilder, Jin Jiang, Yongbin Chen, 2013, Biochemical and biophysical research communications.

Gilgamesh (Gish)/CK1γ regulates tissue homeostasis and aging in adult Drosophila midgut

Jin Jiang, Yuhong Han, Shuang Li, 2020, The Journal of cell biology.

Dual role of BMP signaling in the regulation of Drosophila intestinal stem cell self-renewal

Jin Jiang, Aiguo Tian, 2017, Fly.

Intestinal stem cell response to injury: lessons from Drosophila

Jin Jiang, Aiguo Tian, Huaqi Jiang, 2016, Cellular and Molecular Life Sciences.

Tristetraprolin-dependent Post-transcriptional Regulation of Inflammatory Cytokine mRNA Expression by Apolipoprotein A-I

X. Deng, Chao-ke Tang, Kai Yin, 2011, The Journal of Biological Chemistry.

Up-regulation of cyclooxygenase-2 gene expression correlates with tumor angiogenesis in human breast cancer

Z. Dai, Xi-jing Wang, Huafeng Kang, 2003 .

Gli Phosphorylation Code in Hedgehog Signal Transduction

Jin Jiang, Mengmeng Zhou, 2022, Frontiers in Cell and Developmental Biology.

Transducing the Hedgehog Signal Across the Plasma Membrane

Yun Zhao, Chao Tong, Jin Jiang, 2007, Fly.

The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation

J. Jia, Jin Jiang, Shuang Li, 2011, Development.

Casein Kinase 2 Promotes Hedgehog Signaling by Regulating both Smoothened and Cubitus Interruptus*

Chao Tong, J. Jia, Yajuan Liu, 2010, The Journal of Biological Chemistry.

Phosphorylation of Ci/Gli by Fused Family Kinases Promotes Hedgehog Signaling.

B. Wang, Jin Jiang, Yuhong Han, 2019, Developmental cell.

YAP antagonizes TEAD-mediated AR signaling and prostate cancer growth

Jin Jiang, Yingzi Yang, Yuchen Liu, 2022, bioRxiv.

Secreted Hedgehog (Hh) proteins control many aspects of growth and patterning

Jin Jiang, K. Amanai, 2001 .

Regulation of wingless signaling by the CKI family in Drosophila limb development.

B. Wang, J. Jia, Lei Zhang, 2006, Developmental biology.

Ci/Gli Phosphorylation by the Fused/Ulk Family Kinases.

Jin Jiang, Yuhong Han, 2022, Methods in molecular biology.

Cell-Based Assays for Smoothened Ubiquitination and Sumoylation.

Jin Jiang, Yuhong Han, 2022, Methods in molecular biology.

Regulation of Smoothened Trafficking in Hedgehog Signal Transduction Cell Signaling

Jin Jiang, Shuang Li, 2019 .

Expression and purification of fused kinase from insect cells for in vitro kinase assay

Jin Jiang, Yuhong Han, 2021, STAR protocols.

Misshapen Connects Food, Mechanosensing, and Intestinal Growth.

Jin Jiang, 2018, Developmental cell.

Damage‐induced regeneration of the intestinal stem cell pool through enteroblast mitosis in the Drosophila midgut

W. Deng, Yi-Chun Huang, Jin Jiang, 2022, The EMBO journal.

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

G. Struhl, Jin Jiang, Gary Struhl, 1998, Nature.

Tissue damage-induced intestinal stem cell division in Drosophila.

Y. Ip, Jin Jiang, A. Amcheslavsky, 2009, Cell stem cell.

Injury-stimulated and self-restrained BMP signaling dynamically regulates stem cell pool size during Drosophila midgut regeneration

B. Wang, Jin Jiang, Aiguo Tian, 2017, Proceedings of the National Academy of Sciences.

Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime

I. Edery, H. Ko, Jin Jiang, 2002, Nature.

Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization

Xuewu Zhang, C. Cowan, Jin Jiang, 2012, Science Signaling.

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

Michael Levine, M. Levine, Jin Jiang, 1993, Cell.

γ-Secretase-regulated Proteolysis of the Notch Receptor by Mitochondrial Intermediate Peptidase*

Daniel R. Dries, Yun Wang, Bing Wang, 2011, The Journal of Biological Chemistry.

Decoding the phosphorylation code in Hedgehog signal transduction

Jin Jiang, Yongbin Chen, 2013, Cell Research.

Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2

Jin Jiang, Cuiping Yang, Yongbin Chen, 2012, Cell Research.

Identification of Domains Responsible for Ubiquitin-Dependent Degradation of dMyc by Glycogen Synthase Kinase 3β and Casein Kinase 1 Kinases

P. Pelicci, F. Serras, D. Grifoni, 2009, Molecular and Cellular Biology.

Overlapping functions of the MAP4K family kinases Hppy and Msn in Hippo signaling

Y. Ip, Jin Jiang, Shuangxi Li, 2015, Cell Discovery.

The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila.

Y. Ip, Lan Xu, S. Kaneko, 2014, Developmental cell.

The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control.

B. Wang, Qing Zhang, Lei Zhang, 2008, Developmental cell.

Dimerization and Cytoplasmic Localization Regulate Hippo Kinase Signaling Activity in Organ Size Control*

Zhaocai Zhou, Yi Lu, Wenqing Wu, 2012, The Journal of Biological Chemistry.

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

B. Wang, J. Jia, Jiong Tang, 2002, Nature.

Hedgehog signaling mechanism and role in cancer.

Jin Jiang, 2021, Seminars in cancer biology.

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

Mark G. F. Sun, D. Rowitch, Kyuho Han, 2009, Proceedings of the National Academy of Sciences.

The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway.

Jin Jiang, Tao Yue, Aiguo Tian, 2012, Developmental cell.

Suppression of KIF22 Inhibits Cell Proliferation and Xenograft Tumor Growth in Tongue Squamous Cell Carcinoma

G. Ren, Jin Jiang, Yi Liu, 2020, BioMed research international.

Hedgehog regulates smoothened activity by inducing a conformational switch

Yun Zhao, Chao Tong, Jin Jiang, 2007, Nature.

Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors.

Chien-Hsiang Wang, Cheng-Ting Chien, C. Chien, 2007, Developmental biology.

The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis.

B. Wang, J. Jia, Jin Jiang, 2003, Genes & development.

Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.

Y. Xiong, Yun Zhao, Qing Zhang, 2015, Developmental cell.

Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I

Liping Luo, B. Wang, Chao Tong, 2004, Nature.

Changing potency by spontaneous fusion

B. Wang, J. Jia, Jiong Tang, 2022 .

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

R. M. Simpson, Cun-Yu Wang, L. Topol, 2010, Proceedings of the National Academy of Sciences.

CDK7 regulates organ size and tumor growth by safeguarding the Hippo pathway effector Yki/Yap/Taz in the nucleus

Jin Jiang, Yingzi Yang, Yuhong Han, 2019, Genes & development.

Drosophila Casein Kinase 2 (CK2) Promotes Warts Protein to Suppress Yorkie Protein Activity for Growth Control*

Rong Zeng, Yi Lu, Mengxin Yin, 2014, The Journal of Biological Chemistry.

Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms.

Lei Zhang, Jin Jiang, Fangfang Ren, 2010, Developmental biology.

Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways

Y. Ip, B. Wang, E. Yun, 2010, Proceedings of the National Academy of Sciences.

Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis

Xiang-yi Ma, Fei Li, Dan-feng Luo, 2017, Oncotarget.

Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail network in the gastrulating embryo

Y. Ip, Jin Jiang, Atish Ganguly, 2005, Development.

Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus.

B. Wang, Yun Zhao, Chao Tong, 2005, Developmental cell.

Overview of Hedgehog Signaling Pathway

C. Hui, Jin Jiang, 2011 .

Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination

Qing Zhang, Jin Jiang, 2021, International Journal of Molecular Sciences.

Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells.

Junling Liu, Hua-Bing Li, Jin Jiang, 2019, Cell metabolism.

Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci

Geng Wu, Yun Zhao, J. Jia, 2013, Nature Communications.

Re-entry into mitosis and regeneration of intestinal stem cells through enteroblast dedifferentiation in Drosophila midguts

W. Deng, Yi-Chun Huang, Jin Jiang, 2021, bioRxiv.

Regulation of Smoothened ubiquitylation and cell surface expression through a Cul4–DDB1–Gβ E3 ubiquitin ligase complex

Jin Jiang, Shuang Li, Y. Cho, 2018, Journal of Cell Science.

Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases

Jin Jiang, Shuang Li, Bing Wang, 2018, Science Signaling.

Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation

B. Wang, Jin Jiang, Guoqiang Ma, 2014, Science Signaling.

Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kap&bgr;2 in Hedgehog signaling

Jin Jiang, Yuhong Han, Qing Shi, 2014, Journal of Cell Science.

Trn/Kapβ2 in Hedgehog signaling

Jin Jiang, Yuhong Han, Qing Shi, 2014 .

Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1

Wenyi Wei, Yunsuk Jeung, K. Chung, 2019, Proceedings of the National Academy of Sciences.

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

Hua-Bing Li, Jing Yi, Jinke Cheng, 2018, Nature Communications.

Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A

Ping Chen, Qing Zhang, Jin Jiang, 2017, Scientific Reports.

Regulation of Smoothened Trafficking and Abundance in Hedgehog Signaling

J. Jia, Jin Jiang, 2022, Frontiers in Cell and Developmental Biology.

Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut

Jin Jiang, Aiguo Tian, 2014, eLife.

Hippo-Independent Regulation of Yki/Yap/Taz: A Non-canonical View

Jin Jiang, Y. Cho, 2021, Frontiers in Cell and Developmental Biology.

Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in Drosophila

K. Jiang, Junkai Fan, J. Jia, 2014, Proceedings of the National Academy of Sciences.

Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration

Y. Ip, Jin Jiang, Yongbin Chen, 2013, Cell Research.

Complementary and Mutually Exclusive Activities of Decapentaplegic and Wingless Organize Axial Patterning during Drosophila Leg Development

G. Struhl, Jin Jiang, 1996, Cell.

Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila

Qing Zhang, Jin Jiang, Cunjie Chang, 2014, Cell Research.

Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis

Yun Zhao, Lei Zhang, Jin Jiang, 2013, Cell Research.

Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K

B. Wang, Jin Jiang, Yuhong Han, 2018, Nature Communications.

Intestinal stem cell response to injury: lessons from Drosophila

Jin Jiang, Aiguo Tian, Huaqi Jiang, 2016, Cellular and Molecular Life Sciences.

Characterization of Smoothened Phosphorylation and Activation.

J. Jia, Jin Jiang, Yuhong Han, 2022, Methods in molecular biology.

Receptor Modifications in Hedgehog Regulation

Jin Jiang, Qing Shi, 2014 .

Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms.

Jin Jiang, Gelin Wang, 2004, Developmental biology.

Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K

B. Wang, Jin Jiang, Yuhong Han, 2018, Nature Communications.

Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus.

J. Jiang, Jin Jiang, K. Amanai, 2000, Genes & development.

Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells

Jin Jiang, Shuang Li, Aiguo Tian, 2015 .