J. Leathart

发表

The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease.

S. Friedman, G. Narla, H. Reeves, 2008, Gastroenterology.

A randomized trial of genotype-guided dosing of warfarin.

N. Eriksson, M. Pirmohamed, P. Williamson, 2013, The New England journal of medicine.

Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes.

G. Aithal, C. Day, J. Leathart, 2007, Gastroenterology.

Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn’s disease in a British population

M. Hudson, J. Leathart, G. Aithal, 2001, Genes and Immunity.

Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide

P. Neuvonen, M. Niemi, J. Backman, 2003, Clinical pharmacology and therapeutics.

Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity

G. Alexander, J. Caldwell, G. Aithal, 2004, Hepatology.

Analysis of Escherichia coli Strains Causing Bacteriuria during Pregnancy: Selection for Strains That Do Not Express Type 1 Fimbriae

D. Gally, J. Pearson, J. Leathart, 2001, Infection and Immunity.

Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease

G. Alexander, M. Allison, H. Yki-Jărvinen, 2014, Cell cycle.

The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies.

L. Valenti, S. Fargion, Q. Anstee, 2012, Journal of hepatology.

No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease.

H. Friess, A. Kolb, D. Schuppan, 2008, Alcoholism, clinical and experimental research.

Genotyping for cytochrome P450 polymorphisms.

J. Leathart, A. Daly, B. King, 2006, Methods in molecular biology.

Cyclooxygenase-2 Polymorphisms and Pancreatic Cancer Susceptibility

G. Özhan, J. Leathart, A. Daly, 2010, Pancreas.

CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes.

G. Mannens, J. Leathart, A. Daly, 2002, Biochemical pharmacology.

CYP3A5 phenotype-genotype correlations in a British population.

J. Leathart, A. Daly, F. Williams, 2003, British journal of clinical pharmacology.

Interaction of FimB and FimE with the fim switch that controls the phase variation of type 1 fimbriae in Escherichia coli K‐12

I. Blomfield, D. Gally, J. Leathart, 1996, Molecular microbiology.

Analysis of Escherichia coli Strains Causing Bacteriuria during Pregnancy: Selection for Strains That Do Not Express Type 1 Fimbriae

D. Gally, J. Leathart, S. J. Keegan, 2001, Infection and Immunity.

Regulation of type 1 fimbrial expression in uropathogenic Escherichia coli : heterogeneity of expression through sequence changes in the fim switch region

D. Gally, J. Leathart, 1998, Molecular microbiology.

The mitochondrial superoxide dismutase 2 (SOD2) targeting sequence polymorphism is associated with fibrotic NAFLD: Consistent evidence from case-control and intra-familial allelic association studies

A. Alisi, M. Manco, C. Day, 2007 .

Genetic evidence for a role for gut flora in the pathogenesis of NASH in humans

C. Mathew, C. Day, J. Leathart, 2006 .

Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease

David C. Jones, M. Vidali, R. Rolla, 2003, Hepatology.

Manganese dependent superoxide dismutase (SOD2) targeting sequence polymorphism is associated with advanced fibrosis in patients with non-alcoholic fatty liver disease

C. Day, J. Leathart, A. Daly, 2003 .

VKORC1 and CYP2C9 genotype and patient characteristics explain a large proportion of the variability in warfarin dose requirement among children.

F. Kamali, L. Brandão, E. Chalmers, 2012, Blood.

Polymorphic Organic Anion Transporting Polypeptide 1B1 is a Major Determinant of Repaglinide Pharmacokinetics

Mikko Niemi, Michel Eichelbaum, P. Neuvonen, 2005, Clinical pharmacology and therapeutics.

large proportion of the variability in warfarin dose requirement among genotype and patient characteristics explain a CYP 2 C 9 and VKORC

F. Kamali, L. Brandão, J. Hanley, 2012 .

Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma.

J. Dufour, H. Reeves, A. Burt, 2014, Journal of hepatology.

Genotyping for CYP2C9 and VKORC1 alleles by a novel point of care assay with HyBeacon® probes.

A. H. Maitland‐van der Zee, M. Wadelius, J. Leathart, 2011, Clinica chimica acta; international journal of clinical chemistry.

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

K. Clément, G. Alexander, M. Allison, 2014, Nature Communications.

TM6SF2 rs58542926 influences hepatic fibrosis

K. Clément, G. Alexander, M. Allison, 2015 .

TM 6 SF 2 rs 58542926 Influences Hepatic Fibrosis Progression in Patients with Non-Alcoholic Fatty Liver Disease

K. Clément, G. Alexander, M. Allison, 2014 .

British Association for the Study of the Liver

A. Perelson, C. Dejong, Y. Ma, 1991 .

Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease

L. N. Valenti, G. Marchesini, M. Zappa, 2010, Gut.

Mitochondrial DNA does not contribute to the heritability of non-alcoholic fatty liver disease.

P. Chinnery, G. Hudson, G. Aithal, 2011, Mitochondrion.

Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis.

M. Vidali, R. Rolla, D. Vay, 2002, Hepatology.

Valine‐alanine manganese superoxide dismutase polymorphism is not associated with alcohol‐induced oxidative stress or liver fibrosis

M. Vidali, R. Rolla, D. Vay, 2002 .

Flucloxacillin-induced liver injury: the extended MHC 57.1 haplotype as a major risk factor

M. Pirmohamed, P. Donaldson, G. Aithal, 2008 .

The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver.

M. Zappa, S. Fargion, C. Day, 2011, Journal of hepatology.

Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis.

G. Aithal, C. Day, J. Leathart, 2000, Pharmacogenetics.

patients with non-alcoholic fatty liver disease are associated with the severity of liver damage in Genetic variants regulating insulin receptor signalling

G. Marchesini, M. Zappa, L. Valenti, 2022 .

Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County.

S. London, W. Navidi, J. Idle, 1997, Carcinogenesis.

Genome-Wide Association Analysis Confirms Importance of PNPLA3 and Identifies Novel Variants Associated With Histologically Progressive Steatohepatitis in NAFLD

K. Clément, J. Rotter, H. Cordell, 2012 .