S. Galic

发表

Macrophage Deletion of SOCS1 Increases Sensitivity to LPS and Palmitic Acid and Results in Systemic Inflammation and Hepatic Insulin Resistance

T. Kay, G. Steinberg, Nirupa Sachithanandan, 2011, Diabetes.

Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.

T. Kay, G. Steinberg, Nirupa Sachithanandan, 2014, The Biochemical journal.

Molecular Mechanisms Underlying the Beneficial Effects of Exercise on Brain Function and Neurological Disorders

J. W. Scott, W. Smiles, A. Gundlach, 2021, International journal of molecular sciences.

Regulation of Pancreatic β-cell Function by the NPY System.

J. W. Scott, S. Galic, J. Oakhill, 2021, Endocrinology.

TCPTP-deficiency in muscle does not alter insulin signalling and glucose homeostasis.

B. Neel, Zhon-Yin Zhang, M. Watt, 2012 .

T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice

B. Neel, M. Watt, T. Tiganis, 2012, Diabetologia.

Coordinated Regulation of Insulin Signaling by the Protein Tyrosine Phosphatases PTP1B and TCPTP

F. Haj, B. Neel, N. Tonks, 2005, Molecular and Cellular Biology.

AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis

B. Kemp, G. Steinberg, Z. Andrews, 2018, eLife.

The myokine meteorin‐like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2

B. Kemp, Min-Jeong Shin, K. Song, 2020, The FEBS journal.

Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice

B. Kemp, H. Thomas, T. Kay, 2017, Cell Death and Differentiation.

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity

D. Eizirik, M. Igoillo-Esteve, J. D. de Haan, 2017, Diabetes.

Meteorin-like (Metrnl) adipomyokine improves glucose tolerance in type 2 diabetes via AMPK pathway

B. Kemp, Min-Jeong Shin, K. Song, 2018, bioRxiv.

Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

B. Kemp, Z. Andrews, M. Lemus, 2016, The Journal of Neuroscience.

AMPK b 1 reduces tumor progression and improves survival in p 53 null mice

P. Muti, B. Kemp, G. Blandino, 2017 .

Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis

P. Meikle, A. Murphy, B. Kemp, 2022, Molecular metabolism.

12 0537 Palanivel_for TYPESETTING

R. Palanivel, G. Steinberg, S. Galic, 2012 .

Absence of the β1 subunit of AMP‐activated protein kinase reduces myofibroblast infiltration of the kidneys in early diabetes

D. Power, B. Kemp, S. Fraser, 2019, International journal of experimental pathology.

Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.

D. Power, B. Kemp, M. Katerelos, 2018, Journal of the American Society of Nephrology : JASN.

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

N. Birnberg, B. Kemp, H. Thomas, 2015, Chemistry & biology.

AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice

Melissa M. Thomas, B. Kemp, T. Pulinilkunnil, 2014, Diabetologia.

Reduced Socs3 expression in adipose tissue protects female mice against obesity-induced insulin resistance

R. Palanivel, S. Jørgensen, G. Steinberg, 2012, Diabetologia.

Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism

Nolan J. Hoffman, B. Kemp, J. Hawley, 2020, Molecular metabolism.

Activation of AMPK reduces the co-transporter activity of NKCC1

D. Power, B. Kemp, S. Fraser, 2014, Molecular membrane biology.

Inhibition of Adenosine Monophosphate–Activated Protein Kinase–3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance

P. Meikle, B. Kemp, G. Steinberg, 2018, Hepatology communications.

The loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability.

A. Bröer, S. Bröer, J. Deitmer, 2003, The Biochemical journal.

AMPK β1 reduces tumor progression and improves survival in p53 null mice

P. Muti, B. Kemp, G. Blandino, 2017, Molecular oncology.

An AMPKα2-specific phospho-switch controls lysosomal targeting for activation.

B. Kemp, J. Petersen, W. Smiles, 2022, Cell reports.

Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator

Nolan J. Hoffman, J. Baell, B. Kemp, 2022, The Biochemical journal.

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins

B. Kemp, M. Parker, C. Langendorf, 2020, The Journal of Biological Chemistry.

Functional analysis of an R311C variant of Ca2+‐calmodulin‐dependent protein kinase kinase‐2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder

B. Kemp, C. Langendorf, A. Gundlach, 2020, Bipolar disorders.

Reactive oxygen species enhance insulin sensitivity.

Atsushi Fukushima, Sofianos Andrikopoulos, M. Febbraio, 2009, Cell metabolism.

T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis

M. Tremblay, M. Watt, S. Andrikopoulos, 2010, Diabetes.

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.

M. Tremblay, D. Godfrey, T. Tiganis, 2011, The Journal of clinical investigation.

Adipose tissue as an endocrine organ

G. Steinberg, S. Galic, Sandra Galic, 2010, Molecular and Cellular Endocrinology.

ATP synthase inhibitory factor 1 (IF1), a novel myokine, regulates glucose metabolism by AMPK and Akt dual pathways

R. Krauss, C. Mantzoros, B. Kemp, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Regulation of Insulin Signaling through Reversible Oxidation of the Protein-tyrosine Phosphatases TC45 and PTP1B*

N. Tonks, D. Buckley, T. Tiganis, 2004, Journal of Biological Chemistry.

Regulation of Insulin Receptor Signaling by the Protein Tyrosine Phosphatase TCPTP

N. Tonks, T. Tiganis, S. Galic, 2003, Molecular and Cellular Biology.

Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis.

P. Muti, B. Kemp, G. Blandino, 2015, The Biochemical journal.

Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity

Ian A. Trounce, R. Palanivel, S. Jørgensen, 2012, Diabetes.

Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.

D. Power, B. Kemp, S. Fraser, 2014, American journal of physiology. Renal physiology.

AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965

B. Kemp, L. Furic, C. Langendorf, 2018, The Journal of Biological Chemistry.

Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1-isoforms

B. Kemp, T. Nero, M. Parker, 2020, Nature Metabolism.

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin–sensitizing effects of metformin

J. Dyck, B. Kemp, D. Hardie, 2013, Nature Medicine.

Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise

J. Dyck, B. Kemp, T. Pulinilkunnil, 2015, Physiological reports.

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity.

B. Kemp, J. Schertzer, D. Izon, 2011, The Journal of clinical investigation.

Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity*

B. Kemp, S. Jørgensen, J. Schertzer, 2010, The Journal of Biological Chemistry.

Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs.

S. Galic, J. Moreira, J. Oakhill, 2019, Biochemical Society transactions.

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

B. Viollet, B. Kemp, K. Sakamoto, 2017, Nature Communications.

Exercise reverses age‐related vulnerability of the retina to injury by preventing complement‐mediated synapse elimination via a BDNF‐dependent pathway

J. Crowston, G. Steinberg, P. van Wijngaarden, 2016, Aging cell.

Significance of Short Chain Fatty Acid Transport by Members of the Monocarboxylate Transporter Family (MCT)

S. Bröer, F. Lang, I. Moschén, 2012, Neurochemical Research.

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.

B. Neel, B. Kahn, N. Sims, 2011, Cell metabolism.

Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.

B. Kemp, G. Steinberg, C. Langendorf, 2014, Chemistry & biology.

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

B. Viollet, B. Kemp, K. Sakamoto, 2017, Nature Communications.

TCPTP attenuates STAT 3 and insulin signaling in the liver to regulate gluconeogenesis

M. Tremblay, M. Watt, S. Andrikopoulos, 2010 .

Liver‐specific suppressor of cytokine signaling‐3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity 1

Sofianos Andrikopoulos, A. Hevener, T. Kay, 2010, Hepatology.

AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance*

A. Hevener, B. Kemp, S. Jørgensen, 2009, The Journal of Biological Chemistry.

Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis.

B. Kemp, R. Brink, G. Steinberg, 2022, Cell reports.

Novel torin1-sensitive phosphorylation sites on the metabolic regulator AMPK revealed by label-free mass spectrometry

B. Kemp, W. Smiles, C. Langendorf, 2021, bioRxiv.

Adipose tissue as an endocrine organ

G. Steinberg, S. Galic, J. Oakhill, 2010, Molecular and Cellular Endocrinology.

Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes

H. Thomas, H. Herzog, Yanchuan Shi, 2021, Molecular metabolism.

Elevated Neuropeptide Y1 Receptor Signaling Contributes to β-cell Dysfunction and Failure in Type 2 Diabetes

H. Thomas, H. Herzog, Yanchuan Shi, 2021, bioRxiv.