Elizabeth Frias

发表

Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers

C. Roberts, V. Myer, C. Mickanin, 2014, Proceedings of the National Academy of Sciences.

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

John A. Tallarico, R. Xavier, C. Mickanin, 2016, eLife.

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells

Gregory McAllister, Sven Schuierer, Gregory R. Hoffman, 2017, Scientific Reports.

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer

Henry W. Long, W. Sellers, Myles A Brown, 2018, Cell reports.

Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes.

Robert C. Altshuler, R. Dolmetsch, A. Kaykas, 2019, Cell reports.

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

Antoine de Weck, Joshua M. Korn, Eric Billy, 2017, Cell.

DNA Repair Profiling Reve als Nonrandom Outcomes at Cas 9-Mediated Breaks Graphical Abstract Highlights

Daniel Capurso, Gregory R. Hoffman, A. May, 2016 .

Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer.

J. Korn, Sreenath V. Sharma, D. Ruddy, 2015, Cancer research.

Genome-Scale CRISPR Screening Identifies Novel Human Pluripotent Gene Networks

R. Dolmetsch, A. Kaykas, M. Salick, 2018, bioRxiv.

DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.

A. May, Jiashun Zheng, D. Capurso, 2016, Molecular cell.

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

Gregory McAllister, Zuncai Wang, Gregory R. Hoffman, 2015, Proceedings of the National Academy of Sciences.

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

Gregory McAllister, Ranjit Randhawa, William Forrester, 2018, Nature Medicine.

P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells

R. Dolmetsch, A. Kaykas, W. Forrester, 2017, bioRxiv.

Engineering digitizer circuits for chemical and genetic screens in human cells

M. Hild, W. Wong, Elizabeth Frias, 2021, Nature Communications.

p 53 inhibits CRISPR – Cas 9 engineering in human pluripotent stem cells

R. Dolmetsch, A. Kaykas, W. Forrester, 2018 .

Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes.

Robert C. Altshuler, R. Dolmetsch, A. Kaykas, 2019, Cell Reports.

Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer.

Joshua M. Korn, Sreenath V. Sharma, D. Ruddy, 2015, Cancer Research.