J. Pitcher

发表

Mechanisms of beta-adrenergic receptor desensitization and resensitization.

R. Lefkowitz, Y. Daaka, J. Pitcher, 1998, Advances in pharmacology.

Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79*

Julie A. Pitcher, Robert J. Lefkowitz, Liaoyuan A. Hu, 2001, The Journal of Biological Chemistry.

The b 2-adrenergic receptor interactswith the Na + / H +-exchanger regulatory factor tocontrol Na + / H + exchange

S. Shenolikar, R. Stoffel, S. Grinstein, 2022 .

Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry.

B. Gibson, D. Williams, C. Holmes, 1988, European journal of biochemistry.

The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

S. Shenolikar, R. Stoffel, S. Grinstein, 1998, Nature.

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton.

J. Pitcher, S. H. Cant, 2005, Molecular biology of the cell.

Purification, crystallization and preliminary X-ray diffraction studies of a complex between G protein-coupled receptor kinase 2 and Gbeta1gamma2.

R. Lefkowitz, D. Lodowski, W. D. Capel, 2003, Acta crystallographica. Section D, Biological crystallography.

Glycogenin is the priming glucosyltransferase required for the initiation of glycogen biogenesis in rabbit skeletal muscle.

P. Cohen, C. Smythe, J. Pitcher, 1988, European journal of biochemistry.

Adrenergic receptors: recent insights into their mechanism of activation and desensitization.

M. Caron, R. Lefkowitz, James Inglese, 1993, Advances in second messenger and phosphoprotein research.

Binding of G protein beta gamma-subunits to pleckstrin homology domains.

R. Lefkowitz, James Inglese, G. Shaw, 1994, The Journal of biological chemistry.

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

David M. Harris, B. DeGeorge, W. Koch, 2008, Proceedings of the National Academy of Sciences.

The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity.

R. Lefkowitz, A. Depaoli-Roach, J. Pitcher, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Maximal activities of enzymes involved in adenosine metabolism in muscle and adipose tissue of rats under conditions of variations in insulin sensitivity

E. Newsholme, E. Blomstrand, J. Pitcher, 1985, FEBS letters.

Effects of adenosine deaminase on the sensitivity of glucose transport, glycolysis and glycogen synthesis to insulin in muscles of the rat.

E. Newsholme, R. Challiss, I. Vlachonikolis, 1988, The International journal of biochemistry.

G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins.

M. Caron, R. Lefkowitz, James Inglese, 1992, Cold Spring Harbor symposia on quantitative biology.

Localization Sequence Contains a DNA-Binding Nuclear G Protein-Coupled Receptor Kinase 5

M. Scott, L. R. Johnson, J. Pitcher, 2004 .

Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases.

R. Stoffel, R. Lefkowitz, Y. Daaka, 1997, Proceedings of the National Academy of Sciences of the United States of America.

alpha-Actinin is a potent regulator of G protein-coupled receptor kinase activity and substrate specificity in vitro.

R. Lefkowitz, V. Bennett, J. Pitcher, 2000, FEBS letters.

The G Protein-coupled Receptor Kinase 2 Is a Microtubule-associated Protein Kinase That Phosphorylates Tubulin*

M. Caron, R. Lefkowitz, Y. Daaka, 1998, The Journal of Biological Chemistry.

Distinct Structural Features of G Protein-Coupled Receptor Kinase 5 (GRK5) Regulate Its Nuclear Localization and DNA-Binding Ability

James D. Robinson, L. R. Johnson, J. Pitcher, 2013, PloS one.

Distinct functional outputs of PTEN signalling are controlled by dynamic association with β‐arrestins

G. Baillie, S. Etienne-Manneville, C. Boularan, 2011, The EMBO journal.

G protein-coupled receptor kinases.

R. Lefkowitz, J. Pitcher, N. Freedman, 1998, Annual review of biochemistry.

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.

J. B. Higgins, M. Caron, P. Casey, 1992, Science.

Targeting G protein-coupled receptor kinases to their receptor substrates

R. Stoffel, R. Lefkowitz, J. Pitcher, 1997, The Journal of Membrane Biology.

- βARK: β-Adrenergic receptor kinases (vertebrates)

R. Lefkowitz, James Inglese, W. Koch, 1995 .

The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange.

S. Shenolikar, R. Stoffel, S. Grinstein, 1998, Nature.

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems.

M. Caron, R. Lefkowitz, M. Lohse, 1992, The Journal of biological chemistry.

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms.

M. Caron, R. Lefkowitz, M. Lohse, 1992, Biochemistry.

Pleckstrin Homology Domain-mediated Membrane Association and Activation of the -Adrenergic Receptor Kinase Requires Coordinate Interaction with G Subunits and Lipid(*)

Julie A. Pitcher, Robert J. Lefkowitz, R. Lefkowitz, 1995, The Journal of Biological Chemistry.

Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor.

Liaoyuan A. Hu, R. Lefkowitz, N. Ringstad, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Identification of NSF as a β-Arrestin1-binding Protein

R. Lefkowitz, R. Premont, F. Lin, 1999, The Journal of Biological Chemistry.

The G protein-coupled receptor phosphatase

Julie A. Pitcher, Robert J. Lefkowitz, R. Lefkowitz, 2000 .

The Role of Sequestration in G Protein-coupled Receptor Resensitization

Julie A. Pitcher, Robert J. Lefkowitz, R. Lefkowitz, 1997, The Journal of Biological Chemistry.

Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ

R. Lefkowitz, D. Lodowski, W. D. Capel, 2003, Science.

of Globo H and SSEA3 in breast cancer stem cells and the involvement of trans-ferases in

David M. Harris, A. Eckhart, L. Vinge, 2008 .

G Protein-coupled Receptor Kinase 6A Phosphorylates the Na+/H+ Exchanger Regulatory Factor via a PDZ Domain-mediated Interaction*

R. Lefkowitz, R. Premont, J. Pitcher, 1999, The Journal of Biological Chemistry.

Regulation of G protein-coupled Receptor Kinase 5 (GRK5) by Actin*

T. Pollard, R. Lefkowitz, J. Pitcher, 1998, Journal of Biological Chemistry.

Phosphatidylinositol 4,5-Bisphosphate (PIP2)-enhanced G Protein-coupled Receptor Kinase (GRK) Activity: LOCATION, STRUCTURE, AND REGULATION OF THE PIP2 BINDING SITE DISTINGUISHES THE GRK SUBFAMILIES*

R. Stoffel, R. Lefkowitz, W. Koch, 1996, The Journal of Biological Chemistry.

Identification of the G Protein-coupled Receptor Kinase Phosphorylation Sites in the Human β2-Adrenergic Receptor*

R. Lefkowitz, J. Pitcher, Z. Fredericks, 1996, The Journal of Biological Chemistry.

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

R. Lefkowitz, J. Moss, N. Vitale, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the G Protein-coupled Receptor Kinase GRK4

M. MacDonald, R. Stoffel, R. Lefkowitz, 1996, The Journal of Biological Chemistry.

Phosphorylation and Chronic Agonist Treatment Atypically Modulate GABAB Receptor Cell Surface Stability*

M. Pangalos, S. Moss, B. Fairfax, 2004, Journal of Biological Chemistry.

Clathrin-mediated Endocytosis of the β-Adrenergic Receptor Is Regulated by Phosphorylation/Dephosphorylation of β-Arrestin1*

R. Lefkowitz, Y. Daaka, F. Lin, 1997, The Journal of Biological Chemistry.

Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration.

M. Cotton, N. Vitale, J. Pitcher, 2006, Molecular biology of the cell.

Identification of the 38-kDa subunit of rabbit skeletal muscle glycogen synthase as glycogenin.

P. Cohen, C. Smythe, D. Campbell, 1987, European journal of biochemistry.

G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade.

James D. Robinson, J. Pitcher, J. Robinson, 2013, Cellular signalling.

Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.

M. Caron, R. Lefkowitz, S. Parsons, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Cooperative Regulation of Extracellular Signal-Regulated Kinase Activation and Cell Shape Change by Filamin A and β-Arrestins

S. Marullo, M. Scott, O. Muntaner, 2006, Molecular and Cellular Biology.

Feedback Inhibition of G Protein-coupled Receptor Kinase 2 (GRK2) Activity by Extracellular Signal-regulated Kinases*

Julie A. Pitcher, Robert J. Lefkowitz, R. Lefkowitz, 1999, The Journal of Biological Chemistry.

Identification of NSF as a beta-arrestin1-binding protein. Implications for beta2-adrenergic receptor regulation.

R. Lefkowitz, R. Premont, F. Lin, 1999, The Journal of biological chemistry.

of Globo H and SSEA3 in breast cancer stem cells and the involvement of trans-ferases in

David M. Harris, A. Eckhart, L. Vinge, 2008 .

The diverse roles of G protein-coupled receptor kinase 2 (GRK2): a focus on regulation of receptor tyrosine kinases (RTKs)

James D. Robinson, J. Pitcher, J. Robinson, 2014 .

G Protein-Coupled Receptor Kinase 5 Contains a DNA-Binding Nuclear Localization Sequence

M. Scott, L. R. Johnson, J. Pitcher, 2004, Molecular and Cellular Biology.

Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2.

R. Lefkowitz, P. Gonzalo, J. Lavergne, 2002, Biochemistry.