L. Bruckner-Tuderman

发表

Mapping health care of rare diseases: the example of epidermolysis bullosa in Germany

A. Reimer, L. Bruckner-Tuderman, H. Ott, 2018, Orphanet Journal of Rare Diseases.

Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling.

J. Jacków, Claus-Werner Franzke, L. Bruckner-Tuderman, 2016, The Journal of investigative dermatology.

Dystrophic Epidermolysis Bullosa Inversa with COL7A1 Mutations and Absence of GDA‐J/F3 Protein

J. Smolle, H. Scheffer, D. Metze, 2003, Pediatric dermatology.

Newer Treatment Modalities in Epidermolysis Bullosa

L. Bruckner-Tuderman, 2019, Indian dermatology online journal.

Absence of the Integrin α3 Subunit Induces an Activated Phenotype in Human Keratinocytes.

M. Boerries, H. Busch, C. Has, 2017, The Journal of investigative dermatology.

Junctional Epidermolysis Bullosa with Renal and Respiratory Involvement: Integrin α[Alpha]3 Mutations

C. Has, L. Bruckner-Tuderman, 2015 .

Disorders of the cutaneous basement membrane zone--the paradigm of epidermolysis bullosa.

C. Has, L. Bruckner-Tuderman, 2014, Matrix biology : journal of the International Society for Matrix Biology.

Integrin α3 mutations with kidney, lung, and skin disease.

Y. Anikster, F. Hildebrandt, V. Vega-Warner, 2012, The New England journal of medicine.

Versican is expressed in the proliferating zone in the epidermis and in association with the elastic network of the dermis

L. Bruckner-Tuderman, M. Dours-Zimmermann, D. Zimmermann, 1994, The Journal of cell biology.

Natural history of growth and anaemia in children with epidermolysis bullosa: a retrospective cohort study

C. Has, F. Schauer, A. Reimer, 2020, The British journal of dermatology.

Dermo‐epidermal separation is associated with induced tenascin expression in human skin

S. Schenk, R. Chiquet‐Ehrismann, L. Bruckner-Tuderman, 1995, The British journal of dermatology.

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

K. Horiuchi, C. Blobel, D. Threadgill, 2012, The Journal of experimental medicine.

Collagen XVI is expressed by human dermal fibroblasts and keratinocytes and is associated with the microfibrillar apparatus in the upper papillary dermis.

S. Grässel, L. Bruckner-Tuderman, H. Schäcke, 1999, Matrix biology : journal of the International Society for Matrix Biology.

Keratinocytes from patients lacking collagen XVII display a migratory phenotype.

K. Tasanen, M. Aumailley, L. Bruckner-Tuderman, 2004, The American journal of pathology.

Cleavage and Oligomerization of Gliomedin, a Transmembrane Collagen Required for Node of Ranvier Formation*

D. Keene, D. Greenspan, Claus-Werner Franzke, 2007, Journal of Biological Chemistry.

Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons

K. Poole, G. Lewin, M. Koch, 2011, Nature Neuroscience.

Latent TGF-beta binding protein LTBP-1 contains three potential extracellular matrix interacting domains.

J. Keski‐Oja, L. Bruckner-Tuderman, C. Unsöld, 2001, Journal of cell science.

UV-B-induced cutaneous inflammation and prospects for antioxidant treatment in Kindler syndrome.

T. Brummer, C. Has, L. Bruckner-Tuderman, 2016, Human Molecular Genetics.

Targeting of Cell Surface Proteolysis of Collagen XVII Impedes Squamous Cell Carcinoma Progression.

S. Lassmann, Claus-Werner Franzke, L. Bruckner-Tuderman, 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

Expanding the COL7A1 mutation database: novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa.

C. Has, J. Kohlhase, L. Bruckner-Tuderman, 2006, The Journal of investigative dermatology.

Immunohistochemical and mutation analyses demonstrate that procollagen VII is processed to collagen VII through removal of the NC-2 domain

L. Bruckner-Tuderman, M. Dours-Zimmermann, D. Zimmermann, 1995, The Journal of cell biology.

Proteinases of the Bone Morphogenetic Protein-1 Family Convert Procollagen VII to Mature Anchoring Fibril Collagen*

R. Timpl, Takako Sasaki, R. Burgeson, 2002, The Journal of Biological Chemistry.

Keratin-dependent thymic stromal lymphopoietin expression suggests a link between skin blistering and atopic disease.

T. Jakob, M. Behr, T. Magin, 2016, The Journal of allergy and clinical immunology.

Cytokines as genetic modifiers in K5–/– mice and in human epidermolysis bullosa simplex

T. Magin, L. Bruckner-Tuderman, W. Roth, 2009, Human mutation.

The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation

J. Höhfeld, R. Leube, C. Has, 2010, Human mutation.

Injury- and inflammation-driven skin fibrosis: The paradigm of epidermolysis bullosa.

L. Bruckner-Tuderman, A. Nyström, 2018, Matrix biology : journal of the International Society for Matrix Biology.

Collagenous Transmembrane Proteins: Recent Insights into Biology and Pathology*

Claus-Werner Franzke, L. Bruckner-Tuderman, P. Bruckner, 2005, Journal of Biological Chemistry.

Role of kindlin-2 in fibroblast functions: implications for wound healing.

C. Has, V. Schacht, L. Bruckner-Tuderman, 2011, The Journal of investigative dermatology.

The immunology of bullous oculo-muco-cutaneous disorders.

W. Sterry, U. Pleyer, C. Hartmann, 1996, Immunology today.

Laminin 332 in junctional epidermolysis bullosa

C. Has, L. Bruckner-Tuderman, D. Kiritsi, 2013, Cell adhesion & migration.

Chapter 147 – Epidermolysis Bullosa

C. Has, L. Bruckner-Tuderman, 2013 .

The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB.

E. Bauer, H. Shimizu, J. Uitto, 2008, Journal of the American Academy of Dermatology.

Epidermal and Epidermal-Dermal Cohesion

L. Bruckner-Tuderman, J. Stanley, 2007 .

Collagen XVII is expressed in human CNS neurons.

I. Alafuzoff, K. Majamaa, K. Tasanen, 2006, Matrix biology : journal of the International Society for Matrix Biology.

Discrete integration of collagen XVI into tissue-specific collagen fibrils or beaded microfibrils.

T. Aigner, S. Grässel, D. Reinhardt, 2003, Matrix biology : journal of the International Society for Matrix Biology.

7th European Conference on Rare Diseases and Orphan Products (ERCD 2014)

L. Bruckner-Tuderman, Daniela Kirstein, 2014 .

Digenic junctional epidermolysis bullosa: mutations in COL17A1 and LAMB3 genes.

L. Bruckner-Tuderman, M. Floeth, 1999, American journal of human genetics.

Loss of desmoglein 1 associated with palmoplantar keratoderma, dermatitis and multiple allergies

T. Jakob, C. Has, L. Bruckner-Tuderman, 2015, The British journal of dermatology.

Progress in epidermolysis bullosa research: toward treatment and cure.

J. Uitto, J. McGrath, U. Rodeck, 2010, The Journal of investigative dermatology.

APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa

E. Purdom, K. Tsai, E. Collisson, 2018, Science Translational Medicine.

Matrix molecules and skin biology.

L. Bruckner-Tuderman, A. Nyström, 2019, Seminars in cell & developmental biology.

Dystrophic Epidermolysis Bullosa: Secondary Disease Mechanisms and Disease Modifiers

L. Bruckner-Tuderman, A. Nyström, D. Kiritsi, 2021, Frontiers in Genetics.

Induction of phenotype modifying cytokines by FERMT1 mutations

T. Kurz, M. Boerries, H. Busch, 2011, Human mutation.

Imatinib mesylate as a novel treatment option for hypereosinophilic syndrome: two case reports and a comprehensive review of the literature

U. Martens, R. Mertelsmann, M. Lübbert, 2005, Annals of Hematology.

C-terminal Truncation Impairs Glycosylation of Transmembrane Collagen XVII and Leads to Intracellular Accumulation*

K. Tasanen, C. Has, Claus-Werner Franzke, 2006, Journal of Biological Chemistry.

Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases

S. Ricard-Blum, N. Thielens, M. Lacroix, 2017, Scientific Reports.

Phased‐array of microcoils allows MR microscopy of ex vivo human skin samples at 9.4 T

J. Hennig, J. Korvink, O. Gruschke, 2015, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

Delayed type hypersensitivity to fusidic acid in patients with chronic dermatitis

L. Bruckner-Tuderman, C. Riess, 1990, The Lancet.

Venous leg ulcers and apoptosis: a TIMP-3-mediated pathway?

F. Di Virgilio, M. Idzko, D. Ferrari, 2004, The Journal of investigative dermatology.

Collagen biosynthesis and type I and type III procollagen mRNA in lichen sclerosus et atrophicus

L. Bruckner-Tuderman, R. Panizzon, T. Vuorio, 2004, Archives of Dermatological Research.

Collagen XVII Is Destabilized by a Glycine Substitution Mutation in the Cell Adhesion Domain Col15*

K. Tasanen, M. Aumailley, L. Bruckner-Tuderman, 2000, The Journal of Biological Chemistry.

Kindlin-1 Is a Phosphoprotein Involved in Regulation of Polarity, Proliferation, and Motility of Epidermal Keratinocytes*

U. Schlötzer-Schrehardt, C. Herz, C. Has, 2006, Journal of Biological Chemistry.

Targeting epidermal lipids for treatment of Mendelian disorders of cornification

R. Happle, C. Has, F. Schauer, 2014, Orphanet Journal of Rare Diseases.

Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity.

C. Has, J. Kohlhase, L. Bruckner-Tuderman, 2011, Human molecular genetics.

Consistency of the Proteome in Primary Human Keratinocytes With Respect to Gender, Age, and Skin Localization*

M. Boerries, H. Busch, J. Dengjel, 2013, Molecular & Cellular Proteomics.

Two Forms of Collagen XVII in Keratinocytes

M. Raghunath, L. Bruckner-Tuderman, H. Schäcke, 1998, The Journal of Biological Chemistry.

Impaired lymphoid extracellular matrix impedes antibacterial immunity in epidermolysis bullosa

J. Dengjel, C. Gretzmeier, Kerstin Thriene, 2018, Proceedings of the National Academy of Sciences.

Loss of collagen VII is associated with reduced transglutaminase 2 abundance and activity.

J. Dengjel, C. Gretzmeier, L. Bruckner-Tuderman, 2014, The Journal of investigative dermatology.

Animal models of epidermolysis bullosa: update 2010.

J. Uitto, J. McGrath, L. Bruckner-Tuderman, 2010, The Journal of investigative dermatology.

Molecular consequences of deletion of the cytoplasmic domain of bullous pemphigoid 180 in a patient with predominant features of epidermolysis bullosa simplex.

A. Sonnenberg, J. Koster, D. Hohl, 2004, The Journal of investigative dermatology.

Mutation reports: epidermolysis bullosa simplex associated with severe mucous membrane involvement and novel mutations in the plectin gene.

J. Uitto, E. Bröcker, D. Zillikens, 2000, The Journal of investigative dermatology.

Mutations in the gene encoding the RER protein FKBP65 cause autosomal-recessive osteogenesis imperfecta.

P. Byers, Brendan H. Lee, D. Eyre, 2010, American journal of human genetics.

Differential Expression of Basement Membrane Components in Lymphatic Tissues

K. Tasanen, A. Liakka, L. Bruckner-Tuderman, 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Correction to Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation [The Journal of Experimental Medicine, 209, 6, (2012) 1105-1119]

K. Horiuchi, C. Blobel, D. Threadgill, 2012 .

Collagenous transmembrane proteins: collagen XVII as a prototype.

K. Tasanen, Claus-Werner Franzke, L. Bruckner-Tuderman, 2003, Matrix biology : journal of the International Society for Matrix Biology.

Novel K5 and K14 mutations in German patients with the Weber-Cockayne variant of epidermolysis bullosa simplex.

L. Bruckner-Tuderman, W. Küster, B. Korge, 1998, The Journal of investigative dermatology.

Epidermolysis bullosa simplex with mottled pigmentation.

S. Rüegger, B. Odermatt, O. Tönz, 1989, Journal of the American Academy of Dermatology.

GENERALIZED ATROPHIC BENIGN EPIDERMOLYSIS-BULLOSA - EITHER 180-KD BULLOUS PEMPHIGOID ANTIGEN (BP180) OR LAMININ-5 IS DEFICIENT

A. Sonnenberg, M. Meurer, H. Scheffer, 1995 .

Genetic diseases of the extracellular matrix: more than just connective tissue disorders

L. Bruckner-Tuderman, P. Bruckner, Peter Bruckner, 1998, Journal of Molecular Medicine.

Implications of intragenic marker homozygosity and haplotype sharing in a rare autosomal recessive disorder: the example of the collagen type XVII (COL17A1) locus in generalised atrophic benign epidermolysis bullosa

A. Sonnenberg, G. T. te Meerman, H. Scheffer, 1997, Human Genetics.

Frequency, function and CLA expression of CD4+CD25+FOXP3+ regulatory T cells in bullous pemphigoid

L. Bruckner-Tuderman, Stefan F Martin, Stefan F. Martin, 2007, Experimental dermatology.

A combination of a common splice site mutation and a frameshift mutation in the COL7A1 gene: absence of functional collagen VII in keratinocytes and skin.

J. Uitto, L. Pulkkinen, B. Pontz, 1997, The Journal of investigative dermatology.

Bullous pemphigoid autoantibodies preferentially recognize phosphoepitopes in collagen XVII.

L. Bruckner-Tuderman, C. Sitaru, J. Kern, 2008, The Journal of investigative dermatology.

Expression of the sweat‐derived innate defence antimicrobial peptide dermcidin is not impaired in Staphylococcus aureus colonization or recurrent skin infections

W. Kern, L. Bruckner-Tuderman, D. Jonas, 2014, Clinical and experimental dermatology.

Expression of innate defense antimicrobial peptides in hidradenitis suppurativa.

W. Kern, L. Bruckner-Tuderman, S. Rieg, 2012, Journal of the American Academy of Dermatology.

Recommendations for the use of rituximab (anti‐CD20 antibody) in the treatment of autoimmune bullous skin diseases §

D. Zillikens, R. Eming, M. Goebeler, 2008, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

Keratinocytes and fibroblasts from a patient with mutilating dystrophic epidermolysis bullosa synthesize drastically reduced amounts of collagen VII: lack of effect of transforming growth factor-beta.

L. Bruckner-Tuderman, J. Lauharanta, A. König, 1992, The Journal of investigative dermatology.

Substrate-specific Modulation of a Multisubstrate Proteinase

A. Oldberg, C. Moali, B. Font, 2005, Journal of Biological Chemistry.

The cutaneous microfibrillar apparatus contains latent transforming growth factor-beta binding protein-1 (LTBP-1) and is a repository for latent TGF-beta1.

M. Raghunath, U. Kubitscheck, R. Peters, 1998, The Journal of investigative dermatology.

Invariant natural killer T cells are enriched at the site of cutaneous inflammation in lupus erythematosus.

D. Isenberg, L. Bruckner-Tuderman, C. Mauri, 2013, Journal of dermatological science.

Plectin expression patterns determine two distinct subtypes of epidermolysis bullosa simplex

J. R. McMillan, M. Akiyama, H. Shimizu, 2010, Human mutation.

Severe mucous membrane involvement in epidermolysis bullosa simplex with muscular dystrophy due to a novel plectin gene mutation

J. Uitto, D. Zillikens, U. Schara, 2004, European Journal of Pediatrics.

Consensus reclassification of inherited epidermolysis bullosa and other disorders with skin fragility

C. Bodemer, J. Uitto, J. McGrath, 2020, The British journal of dermatology.

Cetuximab Therapy of Metastasizing Cutaneous Squamous Cell Carcinoma in a Patient with Severe Recessive Dystrophic Epidermolysis Bullosa

P. Itin, L. Bruckner-Tuderman, A. Arnold, 2009, Dermatology.

Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications.

M. Boerries, J. Dengjel, C. Gretzmeier, 2010, Molecular bioSystems.

Involvement of the ubiquitin‐proteasome system in the stabilization of cell–cell contacts in human keratinocytes

T. Magin, L. Bruckner-Tuderman, S. Löffek, 2012, Experimental dermatology.

Collagen XVII expression correlates with the invasion and metastasis of colorectal cancer.

K. Tasanen, N. Kokkonen, J. Väyrynen, 2015, Human pathology.

Epidermolysis bullosa simplex ogna revisited.

C. Has, J. Kohlhase, L. Bruckner-Tuderman, 2013, The Journal of investigative dermatology.

LAD-1 is absent in a subset of junctional epidermolysis bullosa patients.

Sudha K. Rao, M. Marinkovich, L. Bruckner-Tuderman, 1997, The Journal of investigative dermatology.

Nail changes in epidermolysis bullosa: clinical and pathogenetic considerations

L. Bruckner-Tuderman, R. Baran, U. Schnyder, 1995, The British journal of dermatology.

Pathogenesis of mechanobullous disorders

L. Bruckner-Tuderman, 1992, Experimental dermatology.

Distribution of basement membrane anchoring molecules in normal and transformed endometrium: Altered expression of laminin γ2 chain and collagen type XVII in endometrial adenocarcinomas

Y. Soini, K. Tasanen, A. Liakka, 2004, Journal of Molecular Histology.

IgG autoantibodies from bullous pemphigoid patients recognize multiple antigenic reactive sites located predominantly within the B and C subdomains of the COOH-terminus of BP230.

J. Saurat, L. Borradori, M. Hertl, 2000, The Journal of investigative dermatology.

Type 1 segmental Galli-Galli disease resulting from a previously unreported keratin 5 mutation.

P. Itin, R. Happle, C. Has, 2012, The Journal of investigative dermatology.

Epidermolysis bullosa

J. McGrath, I. Chapple, C. Has, 2020, Nature Reviews Disease Primers.

In Memoriam Marcel Jonkman

L. Bruckner-Tuderman, J. Bauer, L. Borradori, 2019, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

Desmoplakin mutations with palmoplantar keratoderma, woolly hair and cardiomyopathy.

C. Has, R. Cosgarea, L. Bruckner-Tuderman, 2015, Acta dermato-venereologica.

Inherited Bullous Diseases

C. Has, L. Bruckner-Tuderman, 2010 .

Whole-exome sequencing in patients with ichthyosis reveals modifiers associated with increased IgE levels and allergic sensitizations To the

T. Jakob, J. Fischer, C. Has, 2014 .

Gas chromatography-mass spectrometry and molecular genetic studies in families with the Conradi-Hünermann-Happle syndrome.

U. Seedorf, C. Has, L. Bruckner-Tuderman, 2002, The Journal of investigative dermatology.

The Conradi-Hünermann-Happle syndrome (CDPX2) and emopamil binding protein: novel mutations, and somatic and gonadal mosaicism.

C. Has, D. Donnai, L. Bruckner-Tuderman, 2000, Human molecular genetics.

Transforming growth factor-beta stimulates collagen VII expression by cutaneous cells in vitro

A. König, L. Bruckner-Tuderman, A. König, 1992, The Journal of cell biology.

Diversity of Mechanisms Underlying Latent TGF-β Activation in Recessive Dystrophic Epidermolysis Bullosa.

L. Bruckner-Tuderman, A. Nyström, G. Sengle, 2020, The Journal of investigative dermatology.

Combined anti‐inflammatory and low‐dose antiproliferative therapy for squamous cell carcinomas in recessive dystrophic epidermolysis bullosa

C. Has, A. Reimer, L. Bruckner-Tuderman, 2020, Journal of the European Academy of Dermatology and Venereology : JEADV.

No evidence that human papillomavirus is responsible for the aggressive nature of recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma.

J. McGrath, C. Proby, H. Pfister, 2010, The Journal of investigative dermatology.

FERMT1 promoter mutations in patients with Kindler syndrome

L. Levati, C. Has, G. Zambruno, 2015, Clinical genetics.

Shedding of Collagen XVII Ectodomain Depends on Plasma Membrane Microenvironment*

Claus-Werner Franzke, L. Bruckner-Tuderman, E. Zimina, 2005, Journal of Biological Chemistry.

Deletion of the major bullous pemphigoid epitope region of collagen XVII induces blistering, autoimmunization, and itching in mice.

J. Jacków, K. Tasanen, N. Kokkonen, 2015, The Journal of investigative dermatology.

Bullous pemphigoid associated with hypereosinophilic syndrome: simultaneous response to imatinib.

M. Lübbert, L. Bruckner-Tuderman, A. Müller, 2007, Journal of the American Academy of Dermatology.

Ectodomain Shedding Generates Neoepitopes on Collagen XVII, the Major Autoantigen for Bullous Pemphigoid

J. Jacków, A. Schlosser, Claus-Werner Franzke, 2010, The Journal of Immunology.

Bullous Pemphigoid for on Collagen XVII, the Major Autoantigen Ectodomain Shedding Generates Neoepitopes

J. Jacków, A. Schlosser, Claus-Werner Franzke, 2010 .

The Flavonoid Luteolin Inhibits Fcγ-Dependent Respiratory Burst in Granulocytes, but Not Skin Blistering in a New Model of Pemphigoid in Adult Mice

T. Jakob, E. Oswald, Claus-Werner Franzke, 2012, PloS one.

Tissue form of type VII collagen from human skin and dermal fibroblasts in culture.

L. Bruckner-Tuderman, K. Winterhalter, P. Bruckner, 1987, European journal of biochemistry.

Kindlin-2 Mediates Mechanical Activation of Cardiac Myofibroblasts

B. Hinz, S. Clément, B. Wehrle-Haller, 2020, Cells.

Tissue-specific expression and long-term deposition of human collagen VII in the skin of transgenic mice: implications for gene therapy

E. Sat, K. Cheah, L. Bruckner-Tuderman, 2000, Gene Therapy.

Kindlin-1 and -2 have overlapping functions in epithelial cells implications for phenotype modification.

C. Has, L. Bruckner-Tuderman, Yinghong He, 2011, The American journal of pathology.

Amlexanox Enhances Premature Termination Codon Read-Through in COL7A1 and Expression of Full Length Type VII Collagen: Potential Therapy for Recessive Dystrophic Epidermolysis Bullosa.

J. Uitto, J. McGrath, M. Prisco, 2017, The Journal of investigative dermatology.

enhances premature termination codon read-through in COL7A1 and expression of full length type VII collagen: potential therapy for recessive dystrophic epidermolysis bullosa

J. Uitto, J. McGrath, M. Prisco, 2017 .

Intracellular accumulation of collagen VII in cultured keratinocytes from a patient with dominant dystrophic epidermolysis bullosa.

M. Raghunath, L. Bruckner-Tuderman, B. Steinmann, 1994, The Journal of investigative dermatology.

Systemic collagen VII replacement therapy for advanced recessive dystrophic epidermolysis bullosa.

C. Gretzmeier, Mei Chen, D. Woodley, 2021, The Journal of investigative dermatology.

Decorin counteracts disease progression in mice with recessive dystrophic epidermolysis bullosa.

P. Uva, G. Zambruno, D. Abeni, 2019, Matrix biology : journal of the International Society for Matrix Biology.

Plasmin plays a role in the in vitro generation of the linear IgA dermatosis antigen LADB97.

Claus-Werner Franzke, L. Bruckner-Tuderman, L. Sorokin, 2009, The Journal of investigative dermatology.

Tight junctions and compression therapy in chronic venous insufficiency.

M. Idzko, M. Jünger, J. Norgauer, 2006, International journal of molecular medicine.

Radiation-Associated Pemphigus Vulgaris in a Patient With Preceding Malignancy: Treatment With Rituximab as a Valuable Option

M. Mockenhaupt, T. Hashimoto, F. Schauer, 2020, Frontiers in Immunology.

Animal model for dermolytic mechanobullous disease: sheep with recessive dystrophic epidermolysis bullosa lack collagen VII.

F. Ehrensperger, F. Guscetti, L. Bruckner-Tuderman, 1991, The Journal of investigative dermatology.

Demonstration of epitope-spreading phenomena in bullous pemphigoid: results of a prospective multicenter study.

F. Sera, L. Borradori, G. Zambruno, 2011, The Journal of investigative dermatology.

Supramolecular Interactions in the Dermo-epidermal Junction Zone

M. Koch, L. Bruckner-Tuderman, P. Bruckner, 2008, Journal of Biological Chemistry.

Autoantibodies in a subgroup of patients with linear IgA disease react with the NC16A domain of BP1801.

E. Bröcker, D. Zillikens, L. Bruckner-Tuderman, 1998, The Journal of investigative dermatology.

Phenotypic spectrum of epidermolysis bullosa associated with α6β4 integrin mutations

A. Sieron, C. Has, L. Bruckner-Tuderman, 2013, The British journal of dermatology.

Overexpression of the Flii gene increases dermal–epidermal blistering in an autoimmune ColVII mouse model of epidermolysis bullosa acquisita

D. Zillikens, D. Murrell, R. Arkell, 2011, The Journal of pathology.

Transmembrane collagen XVII is a novel component of the glomerular filtration barrier

K. Tasanen, Jyri M. Moilanen, T. Hurskainen, 2012, Cell and Tissue Research.

Molecular mechanisms of phenotypic variability in junctional epidermolysis bullosa

C. Has, J. Kohlhase, L. Bruckner-Tuderman, 2011, Journal of Medical Genetics.

Altered expression of collagen XVII in ameloblastomas and basal cell carcinomas.

T. Salo, K. Tasanen, M. Parikka, 2001, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

The shed ectodomain of collagen XVII/BP180 is targeted by autoantibodies in different blistering skin diseases.

D. Zillikens, K. Tasanen, F. Wojnarowska, 2000, The American journal of pathology.

Novel homozygous and compound heterozygous COL17A1 mutations associated with junctional epidermolysis bullosa.

R. Trüeb, L. Bruckner-Tuderman, H. Schäcke, 1998, The Journal of investigative dermatology.

Three novel homozygous point mutations and a new polymorphism in the COL17A1 gene: relation to biological and clinical phenotypes of junctional epidermolysis bullosa.

J. Uitto, L. Pulkkinen, A. Mauviel, 1997, American journal of human genetics.

Genomic organization of the integrin beta 4 gene (ITGB4): a homozygous splice-site mutation in a patient with junctional epidermolysis bullosa associated with pyloric atresia.

J. Uitto, L. Pulkkinen, L. Bruckner-Tuderman, 1997, Laboratory investigation; a journal of technical methods and pathology.

Keratinocytes from junctional epidermolysis bullosa do adhere and migrate on the basement membrane protein nicein through alpha 3 beta 1 integrin.

D. Schmitt, P. Verrando, J. Lissitzky, 1994, Laboratory investigation; a journal of technical methods and pathology.

Basement membrane antibodies in sera of haematopoietic cell recipients are associated with graft‐versus‐host disease

L. Bruckner-Tuderman, H. Bertz, S. Hofmann, 2010, Journal of the European Academy of Dermatology and Venereology : JEADV.

Cell interactions with the extracellular matrix

K. Unsicker, T. Pihlajaniemi, K. Mark, 2009, Cell and Tissue Research.

The Epidermal Basement Membrane Is a Composite of Separate Laminin- or Collagen IV-containing Networks Connected by Aggregated Perlecan, but Not by Nidogens*

H. Robenek, M. Koch, L. Bruckner-Tuderman, 2012, The Journal of Biological Chemistry.

Collagen XVII promotes integrin-mediated squamous cell carcinoma transmigration--a novel role for alphaIIb integrin and tirofiban.

T. Salo, J. Heino, K. Tasanen, 2006, Experimental cell research.

Prolonged Untreated and Treated Course of a Malignant Melanoma

D. Nashan, L. Bruckner-Tuderman, M. Haufs, 2005, Dermatology.

Contact dermatitis due to use of Octenisept® in wound care

T. Jakob, L. Bruckner-Tuderman, H. Schumann, 2009, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

Mastix, a known herbal allergen, as causative agent in occupation‐related dermatitis

L. Bruckner-Tuderman, A. Volz, P. Radny, 2006, Contact dermatitis.

Ichthyosis bullosa and Bullous Congenital

P. Itin, J. Uitto, J. Benhattar, 2009 .

Autoantibodies in a subgroup of patients with linear IgA disease react with the NC16A domain of BP1801.

E. Bröcker, D. Zillikens, L. Bruckner-Tuderman, 1998, The Journal of investigative dermatology.

Lichen planus pemphigoides: another paraneoplastic bullous disease?

H. Gollnick, C. Zouboulis, L. Bruckner-Tuderman, 1997 .

Epidermolysis bullosa acquisita antigen is the globular carboxyl terminus of type VII procollagen.

R. Burgeson, D. Woodley, M. Reese, 1988, The Journal of clinical investigation.

Hemizygosity for a glycine substitution in collagen XVII: unfolding and degradation of the ectodomain.

K. Tasanen, L. Bruckner-Tuderman, H. Schumann, 2000, The Journal of investigative dermatology.

Cylindroma overexpresses collagen VII, the major anchoring fibril protein.

M. Pfaltz, L. Bruckner-Tuderman, L Bruckner-Tuderman, 1991, The Journal of investigative dermatology.

Some epidermolysis bullosa acquisita sera react with epitopes within the triple‐helical collagenous domain as indicated by immunoelectron microscopy

T. Hashimoto, L. Bruckner-Tuderman, N. Ishii, 2009, The British journal of dermatology.

Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid.

F. Sera, L. Borradori, G. Zambruno, 2008, Clinical immunology.

Development of an ELISA for sensitive and specific detection of IgA autoantibodies against BP180 in pemphigoid diseases

T. Hashimoto, M. Hertl, L. Bruckner-Tuderman, 2011, Orphanet journal of rare diseases.

A single‐center open‐label long‐term comparison of tacrolimus ointment and topical corticosteroids for treatment of atopic dermatitis

M. Mockenhaupt, L. Bruckner-Tuderman, Dorothee Amtage, 2008, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

One goal, different strategies – molecular and cellular approaches for the treatment of inherited skin fragility disorders

M. Röcken, R. Handgretinger, L. Bruckner-Tuderman, 2013, Experimental dermatology.

Laminin 5 mutations in junctional epidermolysis bullosa: molecular basis of Herlitz vs non-Herlitz phenotypes

J. Uitto, L. Pulkkinen, D. Murrell, 2001, Human Genetics.

Overlap of IgA pemphigus and linear IgA dermatosis in a patient with ulcerative colitis: a mere coincidence?

W. Kreisel, M. Hertl, L. Bruckner-Tuderman, 2014, Acta dermato-venereologica.

Epidermolysis bullosa acquisita, a rare late complication of allogeneic bone marrow transplantation?

L. Bruckner-Tuderman, J. Gmür, J. Burger, 1992, Bone marrow transplantation.

Definitions and outcome measures for mucous membrane pemphigoid: recommendations of an international panel of experts.

E. Sprecher, D. Zillikens, D. Fivenson, 2015, Journal of the American Academy of Dermatology.

Dynamic interactions of epidermal collagen XVII with the extracellular matrix: laminin 332 as a major binding partner.

L. Bruckner-Tuderman, A. Nyström, D. Kiritsi, 2011, The American journal of pathology.

Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases

Takashi Hashimoto, Markus F Neurath, Jonas Mudter, 2012, BMC Immunology.

Memory B cells specific for the NC16A domain of the 180 kDa bullous pemphigoid autoantigen can be detected in peripheral blood of bullous pemphigoid patients and induced in vitro to synthesize autoantibodies.

D. Zillikens, K. Tasanen, N. Hunzelmann, 2003, The Journal of investigative dermatology.

Kindler syndrome: Extension of FERMT1 mutational spectrum and natural history

M. del Río, P. Itin, J. Fischer, 2011, Human mutation.

Acitretin in the symptomatic therapy for severe recessive x-linked ichthyosis.

J. Geiger, L. Bruckner-Tuderman, S. Gilardi, 1988, Archives of dermatology.

Revised classification system for inherited epidermolysis bullosa: Report of the Second International Consensus Meeting on diagnosis and classification of epidermolysis bullosa.

E. Bauer, H. Shimizu, J. Uitto, 2000, Journal of the American Academy of Dermatology.

Chronic colitis due to an epithelial barrier defect: the role of kindlin‐1 isoforms

E. Haan, C. Herz, O. Opitz, 2007, The Journal of pathology.

Why human pemphigoid autoantibodies do not trigger disease by the passive transfer into mice?

E. Oswald, L. Bruckner-Tuderman, M. Chiriac, 2012, Immunology letters.

Type VII collagen is a component of cylindroma basement membrane zone

M. Pfaltz, L. Bruckner-Tuderman, U. Schnyder, 1989, Journal of cutaneous pathology.

Recalcitrant Pemphigus Vulgaris Responding to Systemic Tacrolimus

L. Bruckner-Tuderman, J. Kern, S. Hofmann, 2010, Dermatology.

Inherited epidermolysis bullosa: updated recommendations on diagnosis and classification.

E. Bauer, H. Shimizu, J. Uitto, 2014, Journal of the American Academy of Dermatology.

Collagen XVII and BPAG1 expression in the retina: Evidence for an anchoring complex in the central nervous system

K. Tasanen, T. Claudepierre, L. Bruckner-Tuderman, 2005, The Journal of comparative neurology.

Localized sclerosis of the scalp (alopecia porphyrinica) as predominant presentation of porphyria cutanea tarda

D. Nashan, M. Braun‐Falco, L. Bruckner-Tuderman, 2007, Journal of the European Academy of Dermatology and Venereology : JEADV.

Type VII collagen is expressed but anchoring fibrils are defective in dystrophic epidermolysis bullosa inversa

T. Reunala, M. Kero, L. Bruckner-Tuderman, 1990, The British journal of dermatology.

Anchoring fibrils and type VII collagen are absent from skin in severe recessive dystrophic epidermolysis bullosa.

L. Bruckner-Tuderman, P. Bruckner, Y. Mitsuhashi, 1989, The Journal of investigative dermatology.

Rat Model for Dominant Dystrophic Epidermolysis Bullosa: Glycine Substitution Reduces Collagen VII Stability and Shows Gene-Dosage Effect

M. Bader, L. Bruckner-Tuderman, C. Özcelik, 2013, PloS one.

Dominant-negative Effects of COL7A1 Mutations Can be Rescued by Controlled Overexpression of Normal Collagen VII*

S. Spassov, A. Schlosser, L. Bruckner-Tuderman, 2009, The Journal of Biological Chemistry.

Mechanisms of fibroblast cell therapy for dystrophic epidermolysis bullosa: high stability of collagen VII favors long-term skin integrity.

O. Paul, P. Ruther, T. Magin, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy.

T. Bley, R. Fässler, M. Erlacher, 2008, The Journal of clinical investigation.

Patients with recessive dystrophic epidermolysis bullosa develop squamous-cell carcinoma regardless of type VII collagen expression.

J. McGrath, I. Leigh, H. Fassihi, 2007, The Journal of investigative dermatology.

Molecular mechanisms of junctional epidermolysis bullosa: Col 15 domain mutations decrease the thermal stability of collagen XVII.

K. Tasanen, T. Hurskainen, C. Has, 2005, The Journal of investigative dermatology.

Compound heterozygosity for silent and dominant glycine substitution mutations in COL7A1 leads to a marked transient intracytoplasmic retention of procollagen VII and a moderately severe dystrophic epidermolysis bullosa phenotype.

H. Shimizu, T. Nishikawa, L. Bruckner-Tuderman, 1999, The Journal of investigative dermatology.

Clustering of COL7A1 mutations in exon 73: implications for mutation analysis in dystrophic epidermolysis bullosa.

L. Bruckner-Tuderman, W. Küster, H. Schumann, 1999, The Journal of investigative dermatology.

Transient bullous dermolysis of the newborn associated with compound heterozygosity for recessive and dominant COL7A1 mutations.

M. Raghunath, L. Bruckner-Tuderman, W. Küster, 1998, The Journal of investigative dermatology.

Compound heterozygosity for a recessive glycine substitution and a splice site mutation in the COL7A1 gene causes an unusually mild form of localized recessive dystrophic epidermolysis bullosa.

F. Atzori, G. Zambruno, L. Bruckner-Tuderman, 1998, The Journal of investigative dermatology.

Some, but Not All, Glycine Substitution Mutations inCOL7A1 Result in Intracellular Accumulation of Collagen VII, Loss of Anchoring Fibrils, and Skin Blistering*

M. Raghunath, T. Luger, L. Bruckner-Tuderman, 1998, The Journal of Biological Chemistry.

Modulation of disease severity of dystrophic epidermolysis bullosa by a splice site mutation in combination with a missense mutation in the COL7A1 gene.

P. Krajči, S. Naylor, M. Zimmermann, 1997, Human molecular genetics.

Progress in Epidermolysis bullosa research: summary of DEBRA International Research Conference 2012.

J. Uitto, J. McGrath, L. Bruckner-Tuderman, 2013, The Journal of investigative dermatology.

Cutaneous metastases of visceral tumours: a review

D. Nashan, M. Braun‐Falco, R. Szeimies, 2008, Journal of Cancer Research and Clinical Oncology.

Trigeminal trophic syndrome with extensive ulceration following herpes zoster.

L. Bruckner-Tuderman, C. Schempp, O. Kautz, 2009, European journal of dermatology : EJD.

Scalp dermatitis, distinctive hair abnormalities and atopic disease in the ectrodactyly—ectodermal dysplasia—clefting syndrome

B. Wüthrich, G. Burg, L. Bruckner-Tuderman, 1995, The British journal of dermatology.

Ectrodactyly-ectodermal dysplasia-clefting syndrome with scalp dermatitis.

G. Burg, R. Trüeb, L. Bruckner-Tuderman, 1993, Journal of the American Academy of Dermatology.

Increased abundance of Cbl E3 ligases alters PDGFR signaling in recessive dystrophic epidermolysis bullosa.

J. Dengjel, Esther Martínez-Martínez, C. Gretzmeier, 2021, Matrix biology : journal of the International Society for Matrix Biology.

Increased abundance of Cbl E3 ligases alters PDGFR signaling in recessive dystrophic epidermolysis bullosa

J. Dengjel, Esther Martínez-Martínez, C. Gretzmeier, 2021, bioRxiv.

Dystrophic epidermolysis bullosa: pathogenesis and clinical features.

L. Bruckner-Tuderman, Leena Bruckner-Tuderman, 2010, Dermatologic clinics.

Immunohistochemical, ultrastructural, and molecular features of Kindler syndrome distinguish it from dystrophic epidermolysis bullosa.

R. Burgeson, H. Shimizu, T. Nishikawa, 1997, Archives of dermatology.

Anchoring fibrils, collagen VII, and neutral metalloproteases in recessive dystrophic epidermolysis bullosa inversa.

T Gedde-Dahl, L. Bruckner-Tuderman, L Bruckner-Tuderman, 1992, The Journal of investigative dermatology.

Esophageal stenosis in childhood: dystrophic epidermolysis bullosa without skin blistering due to collagen VII mutations.

K. Zimmer, L. Bruckner-Tuderman, H. Schumann, 2002, Gastroenterology.

Plantar involvement correlates with obesity, pain and impaired mobility in epidermolysis bullosa simplex: a retrospective cohort study

J. Fischer, C. Has, Antonia Reimer-Taschenbrecker, 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

Generalized atrophic benign epidermolysis bullosa. Either 180-kd bullous pemphigoid antigen or laminin-5 deficiency.

A. Sonnenberg, M. Meurer, L. Bruckner-Tuderman, 1996, Archives of dermatology.

Increased gene expression of matrix metalloproteinase-3 (stromelysin) in skin fibroblasts from patients with severe recessive dystrophic epidermolysis bullosa.

Y. Okada, I. Hashimoto, L. Bruckner-Tuderman, 1991, Biochemical and biophysical research communications.

Epithelial-mesenchymal interactions enhance expression of collagen VII in vitro.

L. Bruckner-Tuderman, A. König, 1990, The Journal of investigative dermatology.

Investigation of Components of the Dermal-Epidermal Junction Zone In Vitro: Effect of Transforming Growth Factor-beta on Collagen VII Expression

L. Bruckner-Tuderman, A. König, 1993 .

Evidence for a structural abnormality of collagen VII in a patient with dystrophic epidermolysis bullosa inversa.

T. Reunala, L. Bruckner-Tuderman, I. Rantala, 1992, The Journal of investigative dermatology.

Epidermolysis Bullosa Dystrophica Inversa in a Child

M. Pfaltz, L. Bruckner-Tuderman, U. Schnyder, 1990, Pediatric dermatology.

Lack of type VII collagen in unaffected skin of patients with severe recessive dystrophic epidermolysis bullosa.

S. Rüegger, B. Odermatt, L. Bruckner-Tuderman, 1988, Dermatologica.

Network epidermolysis bullosa: molecular pathomechanisms and novel therapeutic approaches

C. Has, L. Bruckner-Tuderman, A. Volz, 2007, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

Epidermolysis bullosa: Molecular pathology of connective tissue components in the cutaneous basement membrane zone.

J. Uitto, C. Has, L. Bruckner-Tuderman, 2018, Matrix biology : journal of the International Society for Matrix Biology.

Molecular diagnostics facilitate distinction between lethal and non-lethal subtypes of junctional epidermolysis bullosa: a case report and review of the literature

C. Garbe, G. Rassner, J. Bauer, 2002, European Journal of Pediatrics.

Deletions within COL7A1 exons distant from consensus splice sites alter splicing and produce shortened polypeptides in dominant dystrophic epidermolysis bullosa.

C. Bodemer, M. Lathrop, Y. Barrandon, 1998, American journal of human genetics.

Heterogeneity of severe dystrophic epidermolysis bullosa: overexpression of collagen VII by cutaneous cells from a patient with mutilating disease.

L. Bruckner-Tuderman, T. Gedde-Dahl, J. Winberg, 1994, The Journal of investigative dermatology.

Collagen VII in severe recessive dystrophic epidermolysis bullosa: expression of mRNA but lack of intact protein product in skin and cutaneous cells in vitro.

J. Uitto, A. Christiano, L. Bruckner-Tuderman, 1994, The Journal of investigative dermatology.

Epidemiology of rare diseases is important

L. Bruckner-Tuderman, 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

Molecular basis of inherited skin-blistering disorders, and therapeutic implications

C. Has, M. Aumailley, L. Bruckner-Tuderman, 2006, Expert Reviews in Molecular Medicine.

[Andrologic studies in patients with X-chromosome recessive ichthyosis].

L. Bruckner-Tuderman, J. Meyer, S. Gilardi, 1988, Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete.

Molecular Heterogeneity of Blistering Disorders: The Paradigm of Epidermolysis Bullosa.

C. Has, L. Bruckner-Tuderman, 2012, The Journal of investigative dermatology.

Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells

J. Bauer, L. Bruckner-Tuderman, U. Koller, 2011, Molecular Cancer Therapeutics.

A simplified laminin nomenclature.

J. Sanes, Takako Sasaki, K. Sekiguchi, 2005, Matrix biology : journal of the International Society for Matrix Biology.

[Erythema annulare centrifugum Darier. Successful therapy with topical calcitriol and 311 nm-ultraviolet B narrow band phototherapy].

M. Braun‐Falco, L. Bruckner-Tuderman, C. Termeer, 2007, Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete.

A Novel Marker of Tissue Junctions, Collagen XXII*

R. Burgeson, D. Keene, M. Koch, 2004, Journal of Biological Chemistry.

[Expression of the extracellular matrix proteoglycan, versican, in human skin].

P. Heitz, L. Bruckner-Tuderman, M. Dours-Zimmermann, 1994, Verhandlungen der Deutschen Gesellschaft fur Pathologie.

TGM5 mutations impact epidermal differentiation in acral peeling skin syndrome.

C. Has, L. Bruckner-Tuderman, Cristina Cobzaru, 2012, The Journal of investigative dermatology.

Conradi–Hünermann–Happle syndrome in males vs. MEND syndrome (male EBP disorder with neurological defects)

R. Happle, C. Has, L. Bruckner-Tuderman, 2012, The British journal of dermatology.

Basement membranes and human disease

L. Bruckner-Tuderman, T. Van Agtmael, Tom Van Agtmael, 2009, Cell and Tissue Research.

Compound heterozygous desmoplakin mutations result in a phenotype with a combination of myocardial, skin, hair, and enamel abnormalities.

J. Uitto, S. Peltonen, J. Peltonen, 2010, The Journal of investigative dermatology.

Successful Treatment of Refractory Pityriasis Rubra Pilaris With Secukinumab.

D. Schuster, L. Bruckner-Tuderman, C. Schempp, 2016, JAMA dermatology.

Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds.

Jay W Fox, J. Fox, T. Krieg, 2010, Journal of proteome research.

Cross-linking of the dermo-epidermal junction of skin regenerating from keratinocyte autografts. Anchoring fibrils are a target for tissue transglutaminase.

M. Raghunath, D. Aeschlimann, M. Meuli, 1996, The Journal of clinical investigation.

Collagen XVII and Its Role in Junctional Epidermolysis Bullosa

C. Has, L. Bruckner-Tuderman, 2015 .

Extracellular Phosphorylation of Collagen XVII by Ecto-Casein Kinase 2 Inhibits Ectodomain Shedding*

B. Schermer, T. Benzing, L. Bruckner-Tuderman, 2007, Journal of Biological Chemistry.

Molecular basis of Kindler syndrome in Italy: novel and recurrent Alu/Alu recombination, splice site, nonsense, and frameshift mutations in the KIND1 gene.

J. McGrath, C. Has, G. Zambruno, 2006, The Journal of investigative dermatology.

Poikiloderma with neutropenia: a novel C16orf57 mutation and clinical diagnostic criteria

P. Itin, C. Has, L. Bruckner-Tuderman, 2010, The British journal of dermatology.

Skin proteomics – analysis of the extracellular matrix in health and disease

J. Dengjel, L. Bruckner-Tuderman, A. Nyström, 2020, Expert review of proteomics.

Altered MCM Protein Levels and Autophagic Flux in Aged and Systemic Sclerosis Dermal Fibroblasts

S. Jimenez, J. Uitto, J. Dengjel, 2014, The Journal of investigative dermatology.

A Deep-Intronic FERMT1 Mutation Causes Kindler Syndrome: An Explanation for Genetically Unsolved Cases.

C. Has, J. Kohlhase, L. Bruckner-Tuderman, 2015, The Journal of investigative dermatology.

Fibrillin and elastin expression in skin regenerating from cultured keratinocyte autografts: morphogenesis of microfibrils begins at the dermo-epidermal junction and precedes elastic fiber formation.

M. Raghunath, T. Bächi, M. Meuli, 1996, The Journal of investigative dermatology.

Petechiae on the fingertips as presenting symptom of dermatitis herpetiformis Duhring

D. Nashan, L. Bruckner-Tuderman, S. Hofmann, 2009, Journal of the European Academy of Dermatology and Venereology : JEADV.

Idiopathic eruptive macular pigmentation in a 7‐year‐old girl: case report and discussion of differences from erythema dyschromicum perstans

D. Metze, D. Nashan, L. Bruckner-Tuderman, 2007, The British journal of dermatology.

Results of a survey of German dermatologists on the therapeutic approaches to pemphigus and bullous pemphigoid

D. Zillikens, M. Sticherling, M. Hertl, 2009, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

Verrucous carcinoma in epidermolysis bullosa simplex is possibly associated with a novel mutation in the keratin 5 gene

C. Has, T. Magin, L. Bruckner-Tuderman, 2012, The British journal of dermatology.

Pro‐inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang‐(1‐7)

B. Hinz, J. Dengjel, C. Gretzmeier, 2021, EMBO molecular medicine.

Global remodelling of cellular microenvironment due to loss of collagen VII

H. Busch, O. Schilling, J. Dengjel, 2013, Molecular systems biology.

Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression.

W. Römer, L. Bruckner-Tuderman, J. Madl, 2016, Cancer research.

Genetically corrected iPSCs as cell therapy for recessive dystrophic epidermolysis bullosa

J. Penninger, D. Wenzel, A. Meixner, 2014, Science Translational Medicine.

Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

J. McGrath, C. Mein, J. Bourdon, 2011, Oncogene.

Alterations of Collagen XVII Expression During Transformation of Oral Epithelium to Dysplasia and Carcinoma

T. Salo, K. Tasanen, M. Parikka, 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors.

J. Ortonne, O. Danos, L. Bruckner-Tuderman, 2003, Human molecular genetics.

A microinjected COL7A1-PAC vector restores synthesis of intact procollagen VII in a dystrophic epidermolysis bullosa keratinocyte cell line.

Y. Barrandon, A. Hovnanian, J. E. Mejía, 2002, Human gene therapy.

Stable integration of large (>100 kb) PAC constructs in HaCaT keratinocytes using an integrin-targeting peptide delivery system

Y. Barrandon, A. Hovnanian, S. Hart, 2000, Gene Therapy.

EB2017-Progress in Epidermolysis Bullosa Research toward Treatment and Cure.

J. Uitto, J. McGrath, L. Bruckner-Tuderman, 2018, The Journal of investigative dermatology.

Molecular pathology of the basement membrane zone in heritable blistering diseases:: The paradigm of epidermolysis bullosa.

J. Uitto, C. Has, L. Bruckner-Tuderman, 2017, Matrix biology : journal of the International Society for Matrix Biology.

Genotype, Clinical Course, and Therapeutic Decision Making in 76 Infants with Severe Generalized Junctional Epidermolysis Bullosa.

H. Schneider, C. Has, S. Söder, 2016, The Journal of investigative dermatology.

High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis Bullosa.

R. Handgretinger, L. Bruckner-Tuderman, I. Hausser, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms

J. Dengjel, Kerstin Thriene, L. Bruckner-Tuderman, 2015, EMBO molecular medicine.

Can type VII collagen injections cure dystrophic epidermolysis bullosa?

L. Bruckner-Tuderman, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

The genetics of skin fragility.

C. Has, L. Bruckner-Tuderman, 2014, Annual review of genomics and human genetics.

Coiled Coils Ensure the Physiological Ectodomain Shedding of Collagen XVII*

J. Jacków, Claus-Werner Franzke, L. Bruckner-Tuderman, 2012, The Journal of Biological Chemistry.

Dystroglycan in skin and cutaneous cells: beta-subunit is shed from the cell surface.

U. Schlötzer-Schrehardt, R. Fässler, C. Has, 2004, The Journal of investigative dermatology.

Pemphigoid gestationis autoantigen, transmembrane collagen XVII, promotes the migration of cytotrophoblastic cells of placenta and is a structural component of fetal membranes.

K. Tasanen, T. Hurskainen, M. Ilves, 2008, Matrix biology : journal of the International Society for Matrix Biology.

Disruption of ERBB2IP is not associated with dystrophic epidermolysis bullosa in both father and son carrying a balanced 5;13 translocation.

K. Kutsche, C. Has, L. Bruckner-Tuderman, 2005, The Journal of investigative dermatology.

Characterization of a 50-kDa Component of Epithelial Basement Membranes Using GDA-J/F3 Monoclonal Antibody*

M. Aumailley, L. Bruckner-Tuderman, A. Jassim, 1997, The Journal of Biological Chemistry.

A familial case of tricho‐rhino‐phalangeal syndrome type III with a novel missense mutation in exon 6 of the TRPS1 gene

D. Nashan, L. Bruckner-Tuderman, H. Lüdecke, 2010, Journal of the European Academy of Dermatology and Venereology : JEADV.

RhoA activation by CNFy restores cell–cell adhesion in kindlin‐2‐deficient keratinocytes

J. Dengjel, C. Has, L. Bruckner-Tuderman, 2014, The Journal of pathology.

Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs

F. Fahrenholz, David C. Lee, S. Sunnarborg, 2002, The EMBO journal.

Epithelial and Mesenchymal Cell Biology Kindlin-1 Is Required for RhoGTPase-Mediated Lamellipodia Formation in Keratinocytes

C. Herz, C. Has, M. Aumailley, 2010 .

The autoantigen in anti-p200 pemphigoid is synthesized by keratinocytes and fibroblasts and is distinct from nidogen-2.

Takako Sasaki, R. Trüeb, L. Bruckner-Tuderman, 2008, The Journal of investigative dermatology.

Novel and recurrent mutations in the laminin-5 genes causing lethal junctional epidermolysis bullosa: molecular basis and clinical course of Herlitz disease

L. Bruckner-Tuderman, H. Schneider, C. Mühle, 2004, Human Genetics.

Identification of novel and known KRT5 and KRT14 mutations in 53 patients with epidermolysis bullosa simplex: correlation between genotype and phenotype

T. Krieg, C. Has, L. Bruckner-Tuderman, 2010, The British journal of dermatology.

Novel and recurrent mutations in keratin KRT5 and KRT14 genes in epidermolysis bullosa simplex: implications for disease phenotype and keratin filament assembly

T. Krieg, L. Bruckner-Tuderman, W. Küster, 2006, Human mutation.

Novel and recurrent AAGAB mutations: clinical variability and molecular consequences.

T. Jakob, C. Has, L. Bruckner-Tuderman, 2013, The Journal of investigative dermatology.

Molecular and diagnostic aspects of genetic skin fragility.

C. Has, L. Bruckner-Tuderman, 2006, Journal of dermatological science.

Collagen VII plays a dual role in wound healing.

L. Bruckner-Tuderman, A. Nyström, J. Kern, 2013, The Journal of clinical investigation.

Junctional epidermolysis bullosa with LAMB3 splice-site mutations.

K. Tasanen, N. Kokkonen, C. Has, 2015, Acta dermato-venereologica.

Shedding of Collagen XVII/BP180 in Skin Depends on Both ADAM10 and ADAM9*

C. Blobel, Claus-Werner Franzke, L. Bruckner-Tuderman, 2009, The Journal of Biological Chemistry.

Shedding of Collagen XXIII Is Mediated by Furin and Depends on the Plasma Membrane Microenvironment*

Claus-Werner Franzke, M. Koch, L. Bruckner-Tuderman, 2007, Journal of Biological Chemistry.

Collagen VII Half-Life at the Dermal-Epidermal Junction Zone: Implications for Mechanisms and Therapy of Genodermatoses.

L. Guey, R. Handgretinger, L. Bruckner-Tuderman, 2016, The Journal of investigative dermatology.

Acral peeling skin syndrome with TGM5 gene mutations may resemble epidermolysis bullosa simplex in young individuals.

C. Has, Claus-Werner Franzke, J. Kohlhase, 2010, The Journal of investigative dermatology.

Acral Peeling Skin Syndrome Resembling Epidermolysis Bullosa Simplex in a 10-Month-Old Boy

C. Has, L. Bruckner-Tuderman, I. Yordanova, 2013, Case Reports in Dermatology.

Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders

Richard C. Gerum, B. Fabry, J. Dengjel, 2019, EBioMedicine.

Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes*

T. Reinheckel, R. Backofen, J. Dengjel, 2018, Molecular & Cellular Proteomics.

Mild Clinical Phenotype of Kindler Syndrome Associated with Late Diagnosis and Skin Cancer

P. Itin, C. Has, L. Bruckner-Tuderman, 2010, Dermatology.

A novel large FERMT1 (KIND1) gene deletion in Kindler syndrome.

C. Herz, C. Has, J. Kohlhase, 2008, Journal of dermatological science.

Mechanisms of natural gene therapy in dystrophic epidermolysis bullosa.

M. del Río, Marta García, María José Escamez, 2014, The Journal of investigative dermatology.

The international dystrophic epidermolysis bullosa patient registry: An online database of dystrophic epidermolysis bullosa patients and their COL7A1 mutations

Morris A Swertz, Cristina Has, Trebor Rengaw, 2011, Human mutation.

Novel and recurrent KIND1 mutations in two patients with Kindler syndrome and severe mucosal involvement.

C. Herz, C. Has, L. Bruckner-Tuderman, 2007, Acta dermato-venereologica.

A novel nonsense mutation in Kindler syndrome.

C. Has, L. Bruckner-Tuderman, 2004, The Journal of investigative dermatology.

Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination.

R. Happle, C. Has, L. Bruckner-Tuderman, 2012, The Journal of clinical investigation.

C‐terminally truncated kindlin‐1 leads to abnormal adhesion and migration of keratinocytes

C. Herz, S. Ussar, C. Has, 2008, The British journal of dermatology.

Forty‐two novel COL7A1 mutations and the role of a frequent single nucleotide polymorphism in the MMP1 promoter in modulation of disease severity in a large European dystrophic epidermolysis bullosa cohort

C. Has, S. Emmert, L. Bruckner-Tuderman, 2009, The British journal of dermatology.

The Cell Adhesion Domain of Type XVII Collagen Promotes Integrin-mediated Cell Spreading by a Novel Mechanism*

J. Heino, K. Tasanen, J. Käpylä, 2001, The Journal of Biological Chemistry.

Epidermolysis bullosa

C. Has, L. Bruckner-Tuderman, 2011, Der Hautarzt.

Transmembrane collagen XVII is a novel component of the glomerular filtration barrier

K. Tasanen, Jyri M. Moilanen, T. Hurskainen, 2012, Cell and Tissue Research.

Natural history and clinical outcome of junctional epidermolysis bullosa generalized intermediate due to a LAMA3 mutation

H. Schneider, C. Has, F. Schauer, 2018, The British journal of dermatology.

The extracellular domain of BP180 binds laminin-5

L. Bruckner-Tuderman, G. Giudice, H. Tran, 1998 .

Short Communication Kindlin-1 and -2 Have Overlapping Functions in

Leena Bruckner-Tuderman, Yinghong He, Philipp R. Esser, 2011 .

Introduction of diagnosis-related groups in Germany: evaluation of impact on in-patient care in a dermatological setting.

N. Roeder, T. Luger, S. Beissert, 2008, European journal of public health.

A new clinical variant of acquired reactive perforating dermatosis‐like bullous pemphigoid

H. Shimizu, F. Schauer, L. Bruckner-Tuderman, 2018, The British journal of dermatology.

Immunomapping of EBA sera to multiple epitopes on collagen VII: further evidence that anchoring fibrils originate and terminate in the lamina densa

J. R. McMillan, H. Shimizu, T. Hashimoto, 2003, Experimental dermatology.

An Acquired Bullous Dermatosis of Childhood with Autoantibodies against the Triple-helical Domain of Type VII Collagen.

H. Iizuka, T. Hashimoto, Toshihiro Tanaka, 1999 .

Conceptualization and Implementation of the Central Information Portal on Rare Diseases: Protocol for a Qualitative Study

Ana Babac, Svenja Litzkendorf, Martin Frank, 2018, JMIR research protocols.

Transmembrane Collagen XVII Modulates Integrin Dependent Keratinocyte Migration via PI3K/Rac1 Signaling

O. Schilling, J. Jacków, K. Tasanen, 2014, PloS one.

The missense mutation p.R1303Q in type XVII collagen underlies junctional epidermolysis bullosa resembling Kindler syndrome.

M. Simpson, P. Itin, J. McGrath, 2014, The Journal of investigative dermatology.

Deletion of the cytoplasmatic domain of BP180/collagen XVII causes a phenotype with predominant features of epidermolysis bullosa simplex.

E. Lane, D. Hohl, M. Huber, 2002, The Journal of investigative dermatology.

EGFR inhibition for metastasized cutaneous squamous cell carcinoma in dystrophic epidermolysis bullosa

J. Ruf, L. Bruckner-Tuderman, C. Pfannenberg, 2019, Orphanet Journal of Rare Diseases.

Generation of a Functional Non-Shedding Collagen XVII Mouse Model: Relevance of Collagen XVII Shedding in Wound Healing.

J. Jacków, K. Tasanen, A. Schlosser, 2016, Journal of Investigative Dermatology.

Shedding of Collagen XVII/BP180

K. Tasanen, L. Borradori, Claus-Werner Franzke, 2004, Journal of Biological Chemistry.

179 Systemic administration of HMGB1 peptide drastically improves survival of the RDEB model mice by mobilizing multipotent stem/progenitor cells from bone marrow

Y. Kaneda, J. Uitto, K. Tamai, 2017 .

Grey spots in a patient with dystrophic epidermolysis bullosa

L. Bruckner-Tuderman, F. Meiss, D. Kiritsi, 2010, The British journal of dermatology.

Extensive postzygotic mosaicism for a novel keratin 10 mutation in epidermolytic ichthyosis.

R. Happle, C. Has, J. Kohlhase, 2014, Acta dermato-venereologica.

Multidisciplinary care of epidermolysis bullosa during the COVID-19 pandemic—Consensus: Recommendations by an international panel of experts

C. Bodemer, J. Uitto, E. Sprecher, 2020, Journal of the American Academy of Dermatology.

Skin Fragility: Perspectives on Evidence-based Therapies

L. Bruckner-Tuderman, 2020, Acta dermato-venereologica.

Progress in molecular dermatology.

J. Uitto, L. Bruckner-Tuderman, 2001, Acta Dermato-Venereologica.

Cell‐based therapies for epidermolysis bullosa – from bench to bedside

J. Uitto, C. Has, L. Bruckner-Tuderman, 2012, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

Childhood epidermolysis bullosa acquisita with autoantibodies against all 3 structural domains of type VII collagen.

H. Asada, T. Hashimoto, S. Miyagawa, 2004, Journal of the American Academy of Dermatology.

Most anchoring fibrils in human skin originate and terminate in the lamina densa.

H. Shimizu, T. Nishikawa, L. Bruckner-Tuderman, 1997, Laboratory investigation; a journal of technical methods and pathology.

Point mutations in the regions of the COL7A1 gene coding for the NC-1 and NC-2 domains of collagen VII in patients with recessive epidermolysis bullosa dystrophica (R-EBD)

J. Uitto, L. Bruckner-Tuderman, J. Lauharanta, 1994 .

A case of epidermolysis bullosa acquisita with clinical features of Brunsting-Perry pemphigoid showing an excellent response to colchicine.

T. Dainichi, T. Hashimoto, B. Ohyama, 2009, Journal of the American Academy of Dermatology.

Uniparental Disomy of Chromosome 2 Unmasks New ITGA6 Recessive Mutation and Results in a Lethal Junctional Epidermolysis Bullosa in a Newborn

L. French, M. Schaller, E. Guenova, 2019, Acta dermato-venereologica.

Dystrophic epidermolysis bullosa pruriginosa is not associated with frequent FLG gene mutations

C. Has, L. Bruckner-Tuderman, J. Kohlhase, 2008, The British journal of dermatology.

Junctional epidermolysis bullosa gravis (Herlitz): diagnostic and genetic aspects

U. Wollina, L. Bruckner-Tuderman, R. Hauschild, 2001, Journal of the European Academy of Dermatology and Venereology : JEADV.

Flightless I, a contributing factor to skin blistering in Kindler syndrome patients?

C. Has, Z. Kopecki, A. Cowin, 2020, Journal of cutaneous pathology.

Conditional collagen VII inactivation allows analysis of anchoring fibril stability and function in vivo and reveals a major role of fibroblasts in collagen VII expression

R. Fässler, L. Bruckner-Tuderman, J. Kern, 2009 .

Transforming growth factor-beta promotes deposition of collagen VII in a modified organotypic skin model.

L. Bruckner-Tuderman, A. König, 1994, Laboratory investigation; a journal of technical methods and pathology.

Lipid Rafts and Bullous Diseases

L. Bruckner-Tuderman, E. Zimina, 2009 .

Incontinentia pigmenti in a newborn with a novel nonsense mutation in the NEMO gene

C. Has, L. Bruckner-Tuderman, A. Volz, 2007, The British journal of dermatology.

Novel keratin 14 mutations in patients with severe recessive epidermolysis bullosa simplex.

Yow-Ren Chang, C. Has, J. Kohlhase, 2006, The Journal of investigative dermatology.

Cloning of genes for basement membrane proteins and discovery of mutations in epidermolysis bullosa.

L. Bruckner-Tuderman, 2008, The Journal of investigative dermatology.

Molecular heterogeneity of epidermolysis bullosa simplex: contribution of EXPH5 mutations.

C. Has, J. Kohlhase, L. Bruckner-Tuderman, 2014, The Journal of investigative dermatology.

Molecular heterogeneity of blistering disorders: the paradigm of epidermolysis bullosa.

C. Has, L. Bruckner-Tuderman, 2012, Journal of Investigative Dermatology.

Reduced numbers of circulating γδ T cells in patients with bullous pemphigoid

T. Jakob, E. Oswald, P. Fisch, 2009, Experimental dermatology.

Lupus vulgaris–a case diagnosed more than 20 years after onset

A. Sammain, L. Bruckner-Tuderman, C. Schempp, 2006, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

Biology of anchoring fibrils: lessons from dystrophic epidermolysis bullosa.

L. Bruckner-Tuderman, L. Bruckner-Tuderman, B. Höpfner, 1999, Matrix biology : journal of the International Society for Matrix Biology.

Guidelines on the use of extracorporeal photopheresis

A. Enk, C. Klemke, H. Pehamberger, 2013, Journal of the European Academy of Dermatology and Venereology : JEADV.

Whole-exome sequencing in patients with ichthyosis reveals modifiers associated with increased IgE levels and allergic sensitizations.

T. Jakob, J. Fischer, C. Has, 2015, The Journal of allergy and clinical immunology.

Proteomic profiling of fibroblasts isolated from chronic wounds identifies disease-relevant signaling pathways.

J. Dengjel, C. Gretzmeier, Kerstin Thriene, 2020, The Journal of investigative dermatology.

Antibodies to tissue transglutaminase as serologic markers in patients with dermatitis herpetiformis.

D. Schuppan, T. Zágoni, T. Reunala, 1999, The Journal of investigative dermatology.

Dystrophic epidermolysis bullosa complicated by cutaneous squamous cell carcinoma and pulmonary and renal amyloidosis

L. Bruckner-Tuderman, L. Bruckner-Tuderman, Z. Szalai, 2003, Clinical and experimental dermatology.

Epidermotropic scrotal metastasis of colorectal cancer

M. Braun‐Falco, L. Bruckner-Tuderman, J. Reuter, 2007, International Journal of Colorectal Disease.

Progress Towards Treatment and Cure of Epidermolysis Bullosa: Summary of the DEBRA International Research Symposium EB2015

J. Uitto, J. McGrath, A. Christiano, 2015, The Journal of investigative dermatology.

Global proteome analyses of SILAC-labeled skin cells.

J. Dengjel, L. Bruckner-Tuderman, Victoria Küttner, 2013, Methods in molecular biology.

Pyoderma gangraenosum of the Eyelids

L. Bruckner-Tuderman, Schnyder Uw, 1989 .

Expression of type VII collagen, the major anchoring fibril component, in normal and neoplastic human nervous system

I. Leigh, W. Paulus, L. Bruckner-Tuderman, 2004, Virchows Archiv.

STAT3 targeting in dystrophic epidermolysis bullosa

C. Gretzmeier, C. Gaggioli, L. Bruckner-Tuderman, 2019, The British journal of dermatology.

Injury- and inflammation-driven skin fibrosis: The paradigm of epidermolysis bullosa.

L. Bruckner-Tuderman, A. Nyström, 2018, Matrix biology : journal of the International Society for Matrix Biology.

Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes*

T. Reinheckel, R. Backofen, J. Dengjel, 2018, Molecular & Cellular Proteomics.

Molecular Heterogeneity of Blistering Disorders: The Paradigm of Epidermolysis Bullosa.

C. Has, L. Bruckner-Tuderman, 2012, The Journal of investigative dermatology.

Integrin α3 mutations with kidney, lung, and skin disease.

Y. Anikster, F. Hildebrandt, V. Vega-Warner, 2012, The New England journal of medicine.

Perifollicular protrusions – mid‐dermal elastolysis

M. Braun‐Falco, L. Bruckner-Tuderman, A. Volz, 2009, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.

The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation

J. Höhfeld, R. Leube, C. Has, 2010, Human mutation.

Supramolecular Interactions in the Dermo-epidermal Junction Zone

M. Koch, L. Bruckner-Tuderman, P. Bruckner, 2008, Journal of Biological Chemistry.

The Status Quo of Rare Diseases Centres for the Development of a Clinical Decision Support System - A Cross-Sectional Study

Holger Storf, Thomas Ganslandt, Martin Boeker, 2020, dHealth.

Basement membrane antibodies in sera of haematopoietic cell recipients are associated with graft‐versus‐host disease

L. Bruckner-Tuderman, H. Bertz, S. Hofmann, 2010, Journal of the European Academy of Dermatology and Venereology : JEADV.

Progress in Epidermolysis bullosa research: summary of DEBRA International Research Conference 2012.

J. Uitto, L. Bruckner-Tuderman, E. Robinson, 2013, Journal of Investigative Dermatology.

Childhood epidermolysis bullosa acquisita

L. Bruckner-Tuderman, L. Bruckner-Tuderman, L. Braathen, 1994, The British journal of dermatology.

Epidermolysis bullosa

C. Has, J. Mellerio, L. Bruckner-Tuderman, 2020, Nature Reviews Disease Primers.

Systemic therapy for a genetic skin disease.

L. Bruckner-Tuderman, 2010, The New England journal of medicine.

Isolated NC16a-ELISA testing is of little value to identify bullous pemphigoid in elderly patients with chronic pruritus.

L. Borradori, L. Bruckner-Tuderman, S. Hofmann, 2009, European journal of dermatology : EJD.

Small-molecule therapies for genetic skin fragility.

L. Bruckner-Tuderman, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Acral peeling skin syndrome with TGM5 gene mutations may resemble epidermolysis bullosa simplex in young individuals.

C. Has, Claus-Werner Franzke, J. Kohlhase, 2010, The Journal of investigative dermatology.

Induction of phenotype modifying cytokines by FERMT1 mutations

T. Kurz, M. Boerries, H. Busch, 2011, Human mutation.

Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications.

M. Boerries, J. Dengjel, C. Gretzmeier, 2010, Molecular bioSystems.

Amlexanox Enhances Premature Termination Codon Read-Through in COL7A1 and Expression of Full Length Type VII Collagen: Potential Therapy for Recessive Dystrophic Epidermolysis Bullosa.

J. Uitto, J. McGrath, M. Prisco, 2017, The Journal of investigative dermatology.