Chun‐Hung Chan

发表

The IDeaS initiative: pilot study to assess the impact of rare diseases on patients and healthcare systems

M. Haendel, J. Rutter, A. Pariser, 2021, Orphanet Journal of Rare Diseases.

Osmotic Stress Changes the Expression and Subcellular Localization of the Batten Disease Protein CLN3

D. Pearce, Chun‐Hung Chan, A. Kovács, 2013, PloS one.

BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution

D. Pearce, Chun‐Hung Chan, S. Padilla-Lopez, 2011, Disease Models & Mechanisms.

A porcine model of neurofibromatosis type 1 that mimics the human disease.

D. Meyerholz, D. Quelle, B. Darbro, 2018, JCI insight.

The role of nonsense-mediated decay in neuronal ceroid lipofuscinosis.

D. Pearce, Chun‐Hung Chan, Jake N. Miller, 2013, Human molecular genetics.

Neurodevelopmental delay in the Cln3Δex7/8 mouse model for Batten disease

B. Sampaio-Marques, N. Osório, D. Pearce, 2009, Genes, brain, and behavior.

Transcript and in silico analysis of CLN3 in juvenile neuronal ceroid lipofuscinosis and associated mouse models.

H. Mitchison, D. Pearce, Chun‐Hung Chan, 2008, Human molecular genetics.

Plasma biomarkers for neuronal ceroid lipofuscinosis

Chun‐Hung Chan, David A. Pearce, Samantha L. Hersrud, 2016, The FEBS journal.

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease

J. Cooper, T. Gillingwater, M. Sands, 2009, Human molecular genetics.

A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease.

D. Meyerholz, B. Darbro, Xiao-jun Wang, 2015, Human molecular genetics.

Recommendations from the IRDiRC Working Group on methodologies to assess the impact of diagnoses and therapies on rare disease patients

Chun‐Hung Chan, David A. Pearce, G. Zanello, 2022, Orphanet Journal of Rare Diseases.

Immunosuppression alters disease severity in juvenile Batten disease mice

J. Cooper, D. Pearce, Chun‐Hung Chan, 2011, Journal of Neuroimmunology.

Enhanced GABAA Receptor‐Mediated Activity Following Activation of NMDA Receptors in Cajal‐Retzius Cells in the Developing Mouse Neocortex

H. Yeh, Chun‐Hung Chan, 2003, The Journal of physiology.

Altered arginine metabolism in the central nervous system (CNS) of the Cln3−/− mouse model of juvenile Batten disease

D. Pearce, Chun‐Hung Chan, D. Ramirez-Montealegre, 2009, Neuropathology and applied neurobiology.

Delivering Precision Oncology in a Community Cancer Program: Results From a Prospective Observational Study.

P. Thompson, M. Mazurczak, S. Powell, 2018, JCO precision oncology.

COVID-19 and rare diseases: reflections and recommendations by the International Rare Diseases Research Consortium

D. Julkowska, Lucia Monaco, C. M. Wang, 2021, Rare Disease and Orphan Drugs Journal.

Area identity shifts in the early cerebral cortex of Emx2−/− mutant mice

Luca Muzio, Edoardo Boncinelli, E. Boncinelli, 2000, Nature Neuroscience.

Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones

David J Mooney, D. Mooney, Chun‐Hung Chan, 2010, Proceedings of the National Academy of Sciences.

Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus

Z. Molnár, G. López-Bendito, J. Parnavelas, 2002, The Journal of comparative neurology.

Targeting shared molecular etiologies to accelerate drug development for rare diseases

P. J. Brooks, R. Nabbout, Chun‐Hung Chan, 2023, EMBO molecular medicine.

A porcine model of neurofibromatosis type 1 that mimics the human disease.

D. Meyerholz, D. Quelle, B. Darbro, 2018, JCI insight.

Immunosuppression alters disease severity in juvenile Batten disease mice

J. Cooper, D. Pearce, Chun‐Hung Chan, 2011, Journal of Neuroimmunology.