A. Silver

发表

Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.

J. Bond, Y. Takeuchi, A. Neville, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A major breakpoint cluster domain in murine radiation‐induced acute myeloid leukemia *

R. Cox, J. Haines, J. Moody, 2002, Molecular carcinogenesis.

Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene.

R. Okayasu, R. Ullrich, Y. Yu, 2001, Cancer research.

Interleukin‐1 Beta Gene Deregulation Associated With Chromosomal Rearrangement: A Candidate Initiating Event for Murine Radiation‐Myeloid Leukemogenesis?

R. Cox, A. Shaw, J. Boultwood, 1989, Molecular carcinogenesis.

Adenoma multiplicity in irradiated Apc(Min) mice is modified by chromosome 16 segments from BALB/c.

R. Cox, J. Haines, M. Weil, 2003, Cancer research.

A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse.

R. Okayasu, R. Ullrich, J. Bedford, 2000, Cancer research.

Role of telomeric sequences in murine radiation‐induced myeloid leukaemia

E. van Kampen, S. Bouffler, R. Cox, 1996, Genes, chromosomes & cancer.

Induction of DNA strand breaks by reduced nitroimidazoles. Implications for DNA base damage.

T. C. Jenkins, A. Silver, P. O'Neill, 1986, Biochemical pharmacology.

Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia

A. Rowan, I. Tomlinson, J. Fitzgibbon, 2005, Oncogene.

The phosphate-group of DNA as a potential target for RSU-1069, a nitroimidazole-aziridine radiosensitizer.

T. C. Jenkins, A. Silver, P. O'Neill, 1986, International journal of radiation oncology, biology, physics.

Elongated telomeres in scid mice.

P. Lansdorp, S. Bouffler, P. V. van Buul, 1999, Genomics.

TheIL-1α and β genes are closely linked (<70 kb) on mouse chromosome 2

R. Cox, A. Silver, J. Adam, 1990 .

Mechanism of action of some bioreducible 2-nitroimidazoles: comparison of in vitro cytotoxicity and ability to induce DNA strand breakage.

G. Adams, I. Stratford, T. C. Jenkins, 1987, Anti-cancer drug design.

A biochemical mechanism of resistance to pirimicarb in two glasshouse clones of Aphis gossypii.

A. Silver, M. Battersby, H. Emden, 1995 .

Induction of DNA strand breaks by RSU-1069, a nitroimidazole-aziridine radiosensitizer. Role of binding of both unreduced and radiation-reduced forms to DNA, in vitro.

T. C. Jenkins, A. Silver, P. O'Neill, 1985, Biochemical pharmacology.

Studies on the mechanisms of the radiosensitizing and cytotoxic properties of RSU-1069 and its analogues.

G. Adams, I. Stratford, T. C. Jenkins, 1986, International journal of radiation oncology, biology, physics.

Interaction of the aziridine moiety of RSU-1069 with nucleotides and inorganic phosphate. Implications for alkylation of DNA.

A. Silver, P. O'Neill, 1986, Biochemical pharmacology.

RSU 1069, a nitroimidazole containing an aziridine group. Bioreduction greatly increases cytotoxicity under hypoxic conditions.

G. Adams, I. Stratford, A. Silver, 1986, Biochemical pharmacology.

Mechanistic and genetic studies of radiation tumorigenesis in the mouse--implications for low dose risk estimation.

S. Bouffler, R. Cox, A. Silver, 2002, Journal of radiological protection : official journal of the Society for Radiological Protection.

Loss of heterozygosity in spontaneous and x‐ray–induced intestinal tumors arising in F1 hybrid Min mice: Evidence for sequential loss of Apc+ and Dpc4 in tumor development

R. Cox, J. Haines, J. Moody, 2000, Genes, chromosomes & cancer.

The role of DNA repeats and associated secondary structures in genomic instability and neoplasia

S. Bouffler, R. Cox, A. Silver, 1993, BioEssays : news and reviews in molecular, cellular and developmental biology.

Functional evidence from microcell‐mediated chromosome transfer of myeloid leukemia suppressor genes on human chromosomes 7 and 11

J. Wilding, R. Cox, C. Parris, 2002, Genes, chromosomes & cancer.

Analysis of loss of heterozygosity in lymphoma and leukaemia arising in F1 hybrid mice locates a common region of chromosome 4 loss

J. Wilding, S. Bouffler, R. Cox, 2001, Genes, chromosomes & cancer.

Preliminary molecular studies on two chromosome 2 encoded genes, c-abl and beta 2M, in radiation-induced murine myeloid leukaemias.

R. Cox, A. Silver, W. Masson, 1988, International journal of radiation biology and related studies in physics, chemistry, and medicine.

Murine radiation myeloid leukaemogenesis: Relationship between interstitial telomere‐like sequences and chromosome 2 fragile sites

S. Bouffler, R. Cox, A. Silver, 1993, Genes, chromosomes & cancer.

Radiation-induced chromosome 2 breakage and the initiation of murine radiation acute myeloid leukaemogenesis.

R. Cox, A. Silver, G. Breckon, 1991, Journal of radiation research.

Microsatellite analysis of recurrent chromosome 2 deletions in acute myeloid leukaemia induced by radiation in FI hybrid mice

S. Bouffler, R. Cox, C. Skidmore, 1996, Genes, chromosomes & cancer.

Molecular mapping of chromosome 2 deletions in murine radiation‐induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11–12

P. Finnon, S. Bouffler, R. Cox, 1999, Genes, chromosomes & cancer.

DNA Methylation Changes in the IL‐I (2F) Chromosomal Region of Some Radiation‐Induced Acute Myeloid Leukaemias Carrying Chromosome 2 Rearrangements

R. Cox, A. Silver, J. Adam, 1991, Genes, chromosomes & cancer.

Chromosomal changes: Radiation sensitive sites on chromosome 2 and their role in radiation myeloid leukaemogenesis in the mouse

R. Cox, A. Silver, G. Breckon, 1991, Radiation and environmental biophysics.

Long but dysfunctional telomeres correlate with chromosomal radiosensitivity in a mouse AML cell line

P. Finnon, S. Bouffler, P. Slijepcevic, 2001, International journal of radiation biology.

Upregulation of telomerase activity by X-irradiation in mouse leukaemia cells is independent of Tert, Terc, Tnks and Myc transcription.

P. Finnon, S. Bouffler, A. Silver, 2000, Carcinogenesis.

The opposing roles of Wnt-5a in cancer

A. Silver, A. Silver, S L McDonald, 2009, British Journal of Cancer.

The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action.

I. Stratford, A. Silver, J. Walling, 1986, British Journal of Cancer.

Advances in Brief A Deficiency in DNA Repair and DNA-PKcs Expression in the Radiosensitive BALB / c Mouse 1

R. Okayasu, R. Ullrich, J. Bedford, 2000 .

Somatic cell hybrids for high‐density mapping of chromosome 2 breakpoints in radiation‐induced myeloid leukemia cell lines from inbred mice

S. Bouffler, S. Pazzaglia, A. Saran, 2000, Molecular carcinogenesis.

A telomere-independent senescence mechanism is the sole barrier to Syrian hamster cell immortalization

D. Griffin, A. Silver, A. Cuthbert, 1998, Oncogene.