A. Wright

发表

Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins

J. Reed, M. Walters, K. Welsh, 2014, Journal of biomolecular screening.

The marine natural product Scalarin inhibits the receptor for advanced glycation end products (RAGE) and autophagy in the PANC-1 and MIA PaCa-2 pancreatic cancer cell lines

M. Diaz, A. Wright, E. Guzmán, 2018, Investigational New Drugs.

Antitumor tetrahydroisoquinoline alkaloids from the colonial ascidian Ecteinascidia turbinata

Frank Koehn, Amy E. Wright, F. Koehn, 1990 .

Natural Products from the Lithistida: A Review of the Literature since 2000

S. Pomponi, A. Wright, Priscilla L. Winder, 2011, Marine drugs.

Characterization of genetic markers for in vitro cell line identification of the marine sponge Axinella corrugata.

S. Pomponi, E. Enright, A. Wright, 2002, The Journal of heredity.

DEEP-WATER SINKHOLES AND BIOHERMS OF SOUTH FLORIDA AND THE POURTALÈS TERRACE — HABITAT AND FAUNA

S. Pomponi, C. Paull, A. Wright, 2005 .

Marine sponge bis(indole) alkaloids that displace ligand binding to α1 adrenergic receptors

S. Gunasekera, A. Wright, R. Ramos, 1996 .

In Vitro CuIture of the Tropical Sponge Axinella corrugata (Demospongiae): Effect of Food Cell Concentration on Growth, Clearance Rate, and Biosynthesis of Stevensine

S. Pomponi, A. Wright, A. Duckworth, 2003, Marine Biotechnology.

Discorhabdin P, a new enzyme inhibitor from a deep-water Caribbean sponge of the genus Batzella.

S. Pomponi, J. Clardy, S. Gunasekera, 1999, Journal of natural products.

Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.

A. Wright, I. Paterson, E. Guzmán, 2008, Bioorganic & Medicinal Chemistry Letters.

Dragmacidin, a new cytotoxic bis(indole) alkaloid from a deep water marine sponge, Dragmacidon sp

K. Rinehart, F. Koehn, Y. Kashman, 1988 .

Structure elucidation of a new antifungal sterol sulfate, Sch 575867, from a deep-water marine sponge (Family: Astroscleridae).

S. Pomponi, D. Loebenberg, A. Wright, 2003, The Journal of antibiotics.

Discovery of Survivin Inhibitors Part 1: Screening the Harbor Branch Pure Compound Library

A. Wright, E. Guzmán, T. Pitts, 2021, Marine drugs.

Plakinamine P, A Steroidal Alkaloid with Bactericidal Activity against Mycobacterium tuberculosis

S. Pomponi, M. Diaz, A. Wright, 2019, Marine drugs.

A systematic revision of the Central Atlantic Halichondrida (Demospongiae, Porifera). Part II. Patterns of distribution of secondary metabolites

S. Pomponi, M. Diaz, R. Soest, 1991 .

The Marine Natural Product Manzamine A Targets Vacuolar ATPases and Inhibits Autophagy in Pancreatic Cancer Cells

D. Hoepfner, A. Wright, E. Guzmán, 2013, Marine drugs.

Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin.

A. Wright, I. Paterson, E. Guzmán, 2010, Chemical communications.

High-Throughput Screening of a Marine Compound Library Identifies Anti-Cryptosporidium Activity of Leiodolide A

S. Pomponi, A. Wright, E. Guzmán, 2022, Marine drugs.

Molecular Approaches to Discover Marine Natural Product Anticancer Leads – An Update from a Drug Discovery Group Collaboration

W. Gerwick, K. Bair, P. Crews, 2003 .

Spongiatriol Inhibits Nuclear Factor Kappa B Activation and Induces Apoptosis in Pancreatic Cancer Cells

A. Wright, E. Guzmán, T. Pitts, 2013, Marine drugs.

Chemistry and Biology of the Discodermolides, Potent Mitotic Spindle Poisons

S. Gunasekera, A. Wright, 2005 .

Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.

A. Wright, I. Paterson, E. Guzmán, 2011, Chemistry, an Asian journal.

Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin.

S. Pomponi, R. Isbrucker, A. Wright, 2003, Biochemical pharmacology.

Selective cytotoxic activity of the marine-derived batzelline compounds against pancreatic cancer cell lines

S. Gunasekera, A. Wright, E. Guzmán, 2009, Anti-cancer drugs.

Cytotoxin production by a merineLyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor

A. Wright, K. Janda, J. Armstrong, 1991, Journal of Applied Phycology.

Antiplasmodial Compounds from Deep-Water Marine Invertebrates

S. Pomponi, D. Chakrabarti, M. Diaz, 2021, Marine drugs.

A new bis-(indole) alkaloid from a deep-water marine sponge of the genus Spongosorites

S. Pomponi, A. Wright, P. McCarthy, 1992 .

Metabolites from the marine-derived fungus Chromocleista sp. isolated from a deep-water sediment sample collected in the Gulf of Mexico.

S. Gunasekera, A. Wright, P. McCarthy, 2006, Journal of natural products.

A new bicyclic guanidine alkaloid, Sch 575948, from a marine sponge, Ptilocaulis spiculifer.

S. Pomponi, A. Wright, B. Pramanik, 2003, The Journal of antibiotics.

Discorhabdins S, T, and U, new cytotoxic pyrroloiminoquinones from a deep-water Caribbean sponge of the genus Batzella.

S. Pomponi, Ignacio A Zuleta, S. Gunasekera, 2003, Journal of natural products.

Microxine, a new cdc2 kinase inhibitor from the Australian marine sponge Microxina species.

A. Wright, J. Hooper, K. Killday, 2001, Journal of natural products.

Secobatzellines A and B, two new enzyme inhibitors from a deep-water Caribbean sponge of the genus Batzella.

S. Pomponi, S. Gunasekera, A. Wright, 1999, Journal of natural products.

Diterpene metabolites from two chemotypes of the marine sponge Myrmekioderma styx.

S. Pomponi, A. Wright, S. Sennett, 1992, Journal of natural products.

Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.

Ó. Delgado, A. Wright, I. Paterson, 2004, Chemical communications.

Lateral root inducing compounds from the bacterium Erwinia quercina: Isolation, structure and synthesis

A. Wright, S. Midland, J. J. Sims, 1989 .

Duryne, a new cytotoxic agent from the marine sponge Cribrochalinadura

O. Mcconnell, A. Wright, K. Snader, 1987 .

A new sterol sulfate, Sch 572423, from a marine sponge, Topsentia sp.

S. Pomponi, J. Lachowicz, A. Wright, 2003, Bioorganic & medicinal chemistry letters.

Isolation and structure elucidation of perthamide B, a novel peptide from the sponge Theonella sp.

S. Pomponi, A. Wright, N. Gulavita, 1994 .

Cytotoxic cembranoids from the gorgonian pseudopterogorgia bipinnata

N. Burres, G. Schulte, A. Wright, 1989 .

Analogues of the Potent Antitumor Compound Leiodermatolide from a Deep-Water Sponge of the Genus Leiodermatium.

S. Pomponi, A. Wright, E. Guzmán, 2017, Journal of natural products.

Eryloside E from an atlantic sponge Erylus goffrilleri

M. Kelly-Borges, A. Wright, R. Longley, 1994 .

(+)-Curcuphenol and (+)-Curcudiol, Sesquiterpene Phenols from Shallow and Deep Water Collections of the Marine Sponge Didiscus flavus

S. Pomponi, O. Mcconnell, A. Wright, 1987 .

Isolation and structure elucidation of 34-sulfatobastadin 13, an inhibitor of the endothelin A receptor, from a marine sponge of the genus Ianthella.

M. Kelly-Borges, S. Pomponi, A. Wright, 1993, Journal of natural products.

Lipid reserves and immune defense in healthy and diseased migrating monarchs Danaus plexippus

S. Altizer, A. Wright, Dara A. Satterfield, 2013 .

Interspecific differences in fouling of two congeneric ascidians (Eudistoma olivaceum and E. capsulatum): is surface acidity an effective defense?

A. Davis, A. Wright, 1989 .

In Vitro Production of Marine-Derived Antitumor Compounds

S. Pomponi, A. Wright, R. Willoughby, 1998 .

Inhibition of larval settlement by natural products from the ascidian,Eudistoma olivaceum (Van Name)

A. Davis, A. Wright, 1990, Journal of Chemical Ecology.

Three new peroxides from the sponge Plakinastrella species.

S. Pomponi, C. Selitrennikoff, A. Wright, 2001, Journal of natural products.

Synthetic analogues of the microtubule-stabilizing agent (+)-discodermolide: preparation and biological activity.

S. Gunasekera, A. Wright, T. Pitts, 2001, Journal of natural products.

Selective Killing of Dormant Mycobacterium tuberculosis by Marine Natural Products

S. Pomponi, M. Diaz, A. Wright, 2017, Antimicrobial Agents and Chemotherapy.

Tubercidin, A Cytotoxic Agent from the Marine Sponge Caulospongia biflabellata

S. Pomponi, S. Gunasekera, A. Wright, 2002 .

Two new cytotoxic linderazulenes from a deep-sea gorgonian of the genus Paramuricea.

A. Wright, R. Longley, J. Reed, 2005, Journal of natural products.

Bis(sulfato)-cyclosiphonodictyol A, a new disulfated sesquiterpene-hydroquinone from a deep water collection of the Marine sponge Siphonodictyon coralliphagum.

A. Wright, K. Killday, M. Sills, 1995, Journal of natural products.

The Marine Natural Product Furospinulosin 1 Induces Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cell Spheroids, But Not in Cells Grown Traditionally with Longer Treatment

A. Wright, E. Guzmán, T. Pitts, 2021, Marine drugs.

Lasonolides C-g, five new lasonolide compounds from the sponge Forcepia sp.

S. Pomponi, A. Wright, T. Pitts, 2004, Journal of natural products.

The discovery and characterization of an interleukin 6 cytokine family antagonist protein from a marine sponge, Callyspongia sp.

S. Pomponi, L. Wennogle, A. Wright, 2001, Advances in experimental medicine and biology.

Characterization of an Interleukin 6 Cytokine Family Antagonist Protein from a Marine Sponge, Callyspongia sp.(*)

S. Pomponi, A. Wright, J. Peppard, 1996, The Journal of Biological Chemistry.

Dynamics of microcystins and saxitoxin in the Indian River Lagoon, Florida.

B. Lapointe, A. E. Laureano-Rosario, M. Twardowski, 2021, Harmful algae.

Bioactivity of Marine Organisms: Relationships with Taxonomy, Geography and Depth

S. Pomponi, A. Wright, T. Pitts, 1998 .

Eryloside F, a novel penasterol disaccharide possessing potent thrombin receptor antagonist activity.

P. S. Robinson, S. Pomponi, N. Pike, 2000, Bioorganic & medicinal chemistry letters.

Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima.

S. Pomponi, M. Diaz, A. Wright, 2011, Bioorganic & medicinal chemistry.

Gymnochromes E and F, cytotoxic phenanthroperylenequinones from a deep-water crinoid, Holopus rangii.

A. Wright, J. Reed, A. Wood, 2010, Journal of natural products.

The Lithistida: important sources of compounds useful in biomedical research.

A. Wright, 2010, Current opinion in biotechnology.

An antiviral sesquiterpene hydroquinone from the marine sponge Strongylophora hartmani.

A. Wright, S. Cross, S. Rueth, 1991, Journal of natural products.

Early Effects of Lasonolide A on Pancreatic Cancer Cells

R. Isbrucker, A. Wright, E. Guzmán, 2009, Journal of Pharmacology and Experimental Therapeutics.

Isolation of Marine Natural Products

A. Wright, 1998 .

Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.

R. Isbrucker, D. Divlianska, A. Wright, 2011, Angewandte Chemie.

Dragmacidin G, a Bioactive Bis-Indole Alkaloid from a Deep-Water Sponge of the Genus Spongosorites

S. Pomponi, D. Chakrabarti, A. Wright, 2017, Marine drugs.

Stereochemical Determination of Dictyostatin, a Novel Microtubule‐Stabilizing Macrolide from the Marine Sponge Corallistidae sp.

Ó. Delgado, A. Wright, I. Paterson, 2004 .

Inhibition of IL-8 secretion on BxPC-3 and MIA PaCa-2 cells and induction of cytotoxicity in pancreatic cancer cells with marine natural products

A. Wright, Yi Yu, E. Guzmán, 2017, Anti-cancer drugs.

Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae.

Peter J McCarthy, S. Pomponi, J. Botelho, 2007, Journal of natural products.

The Bis(Indolyl)Imidazole Alkaloid Nortopsentin A Exhibits Antiplasmodial Activity

D. Chakrabarti, A. Wright, Stephenie Alvarado, 2013, Antimicrobial Agents and Chemotherapy.

Total synthesis and biological evaluation of novel C2-C6 region analogues of dictyostatin.

A. Wright, I. Paterson, E. Guzmán, 2009, Bioorganic & medicinal chemistry.

Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.

A. Wright, I. Paterson, Guy J. Naylor, 2008, Chemical communications.

Synthesis and biological evaluation of novel analogues of dictyostatin.

A. Wright, I. Paterson, N. Gardner, 2007, Bioorganic & medicinal chemistry letters.

A new sterol sulfate, Sch 572423, from a marine sponge, Topsentia sp.

S. Pomponi, J. Lachowicz, A. Wright, 2003, Bioorganic & medicinal chemistry letters.

Use of Real-Time qPCR to Quantify Members of the Unculturable Heterotrophic Bacterial Community in a Deep Sea Marine Sponge, Vetulina sp

S. Pomponi, A. Wright, R. Winegar, 2008, Microbial Ecology.

A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis

A. Wright, E. Guzmán, Jacob D. Johnson, 2011, Investigational New Drugs.

Isospongiadiol, a Cytotoxic and Antiviral Diterpene from a Caribbean Deep Water Marine Sponge, Spongia sp.

O. Mcconnell, A. Wright, S. Kohmoto, 1987 .

The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells

A. Wright, E. Guzmán, K. Maers, 2015, Investigational New Drugs.

AUV-Based Environmental Characterization of Deepwater Coral Mounds in the Straits of Florida

S. Pomponi, G. Eberli, M. Grasmueck, 2007 .

New bioactive peroxides from marine sponges of the family plakiniidae.

S. Pomponi, C. Selitrennikoff, A. Wright, 2002, Journal of natural products.

Indolo[3,2-a]carbazoles from a Deep-Water Sponge of the Genus Asteropus

S. Pomponi, A. Wright, P. McCarthy, 2013, Journal of natural products.

Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived Nocardiopsis sp. HB-J378

Haining Zhu, Keshav K. Nepal, Guojun Wang, 2018, Synthetic and systems biotechnology.

Marine Microbiome as a Source of Antimalarials

D. Chakrabarti, A. Carbonell, A. Wright, 2019, Tropical medicine and infectious disease.

Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity

Qunli Xu, A. Wright, Karen Tendyke, 2016, International journal of cancer.

Synthesis and biological evaluation of 10,11-dihydrodictyostatin, a potent analogue of the marine anticancer agent dictyostatin.

Ian Paterson, A. Wright, I. Paterson, 2008, Journal of natural products.

Brominated and Sulfur-Containing Angucyclines Derived from a Single Pathway: Identification of Nocardiopsistins D-F.

Guojun Wang, A. Wright, E. Guzmán, 2022, Organic letters.

In vitro culture of the ascidian Ecteinascidia turbinata to supply the antitumor compounds ecteinascidins

S. Pomponi, A. Wright, A. Duckworth, 2004 .

Puupehenone, a cytotoxic metabolite from a deep water marine sponge, Stronglyophora hartmani.

F. Koehn, A. Wright, O. Mcconnell, 1987, Journal of natural products.

Novel steroidal saponins, Sch 725737 and Sch 725739, from a marine starfish, Novodinia antillensis.

J. Crona, A. Wright, B. Pramanik, 2007, Bioorganic & Medicinal Chemistry Letters.

A new sesterterpene, Sch 599473, from a marine sponge, Ircinia sp.

S. Pomponi, A. Wright, B. Pramanik, 2003, The Journal of antibiotics.

Isolation and Structure Elucidation of Perthamide B, a Novel Peptide from the Sponge Theonella sp.

S. Pomponi, A. Wright, N. Gulavita, 1995 .

Aplysillin A, a thrombin receptor antagonist from the marine sponge Aplysina fistularis fulva.

S. Pomponi, A. Wright, N. Gulavita, 1995, Journal of Natural Products.

Sulfircin: a new sesterterpene sulfate from a deep-water sponge of the genus Ircinia

G. Schulte, A. Wright, P. McCarthy, 1989 .

3-Amino-1-(2-Aminoimidazolyl)-prop-1-ene from the Marine Sponges Teichaxinella morchella and Ptilocaulis walpersi

A. Wright, S. Cross, S. A. Chiles, 1991 .

Characterization and optimization of in vitro assay conditions for (1,3)beta-glucan synthase activity from Aspergillus fumigatus and Candida albicans for enzyme inhibition screening.

S. Pomponi, C. Selitrennikoff, A. Wright, 1998, The Journal of antibiotics.