P. Gagnon

发表

Technology trends in antibody purification.

P. Gagnon, 2012, Journal of chromatography. A.

A simple and efficient purification platform for monoclonal antibody production based on chromatin-directed cell culture clarification integrated with precipitation and void-exclusion anion exchange chromatography.

M. Xian, Rui Nian, Haibo Zhang, 2016, Journal of biotechnology.

Histone-dependent IgG conservation in octanoic acid precipitation and its mechanism

M. Xian, Rui Nian, Haibo Zhang, 2016, Applied Microbiology and Biotechnology.

Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance.

Rui Nian, L. Tan, X. Bi, 2014, Journal of chromatography. A.

Cooperative multimodal retention of IgG, fragments, and aggregates on hydroxyapatite.

P. Gagnon, P. Yazaki, C. Cheung, 2009, Journal of separation science.

CHT Ceramic Hydroxyapatite — A New Dimension in Chromatography of Biological Molecules

P. Gagnon, T. Ogawa, Russ Frost, 2002 .

How to Choose an Industrial Cation Exchanger for IgG Purification

Pete Gagnon, P. Gagnon, 2010 .

Advance chromatin extraction enhances performance and productivity of cation exchange chromatography-based capture of Immunoglobulin G monoclonal antibodies.

Rui Nian, P. Gagnon, 2016, Journal of chromatography. A.

Mechanistic model for adsorption of immunoglobulin on hydroxyapatite.

P. Gagnon, P. Ng, Jie He, 2007, Journal of chromatography. A.

Solvent modulation of column chromatography.

D. Ejima, T. Arakawa, Y. Kita, 2008, Protein and peptide letters.

Antibody aggregate removal by hydroxyapatite chromatography.

P. Gagnon, K. Beam, 2009, Current pharmaceutical biotechnology.

High productivity purification of immunoglobulin G monoclonal antibodies on starch-coated magnetic nanoparticles by steric exclusion of polyethylene glycol.

P. Gagnon, P. Toh, Jeremy Lee, 2014, Journal of chromatography. A.

Conformational plasticity of IgG during protein A affinity chromatography.

Rui Nian, P. Gagnon, 2016, Journal of chromatography. A.

Minibodies and Multimodal Chromatography Methods: A Convergence of Challenge and Opportunity.

Paul J Yazaki, Anna M Wu, Pete Gagnon, 2010, BioProcess international.

Reverse calcium affinity purification of Fab with calcium derivatized hydroxyapatite.

P. Gagnon, P. Yazaki, C. Cheung, 2009, Journal of immunological methods.

Allantoin as a solid phase adsorbent for removing endotoxins.

Vincent Vagenende, P. Gagnon, Tim-Jang Ching, 2013, Journal of chromatography. A.

Suppression of IgM Proteolysis by Conformational Stabilization Through Excipients

P. Gagnon, Monika Mueller, Maybelle Q. T. Loh, 2015, Scientia pharmaceutica.

Characterization and removal of aggregates formed by nonspecific interaction of IgM monoclonal antibodies with chromatin catabolites during cell culture production.

P. Gagnon, Hui Theng Gan, Sarah Maria Abdul Latiff, 2013, Journal of chromatography. A.

Practical Strategies for Protein Contaminant Detection by High-Performance Hydrophobic Interaction Chromatography

P. Gagnon, 2005 .

The effects of hitchhiker antigens co-eluting with affinity-purified research antibodies.

M. Parseghian, P. Gagnon, V. Nguyen, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

PEG enhances viral clearance on ceramic hydroxyapatite.

P. Gagnon, P. Ng, M. Snyder, 2009, Journal of separation science.

Amide-mediated hydrogen bonding at organic crystal/water interfaces enables selective endotoxin binding with picomolar affinity.

Vincent Vagenende, P. Gagnon, Tim-Jang Ching, 2013, ACS applied materials & interfaces.

An adaptation of hydrophobic interaction chromatography for estimation of protein solubility optima.

Å. Danielsson, P. Gagnon, T. Mayes, 1997, Journal of pharmaceutical and biomedical analysis.

Dissociation of Antibody-Contaminant Complexes With Hydroxyapatite

P. Gagnon, 2011 .

Purification of IgM Monoclonal Antibodies : Manufacturing challenges surround the use of IgM monoclonal antibodies, but these can be overcome with current technology

P. Gagnon, F. Hensel, Richard A. Richieri, 2008 .

Principles and applications of steric exclusion chromatography.

Pete Gagnon, S. Ng, P. Gagnon, 2012, Journal of chromatography. A.

Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells

Yuansheng Yang, Xuezhi Bi, Rui Nian, 2015, mAbs.

Practical Strategies for Protein Contaminant Detection by High-Performance Ion-Exchange Chromatography

P. Gagnon, 2005 .

Chromatographic Purification of Virus Particles

P. Gagnon, 2009 .

Monoclonal antibody purification with hydroxyapatite.

Pete Gagnon, P. Gagnon, 2009, New biotechnology.

Accelerating AAV to the Clinic with Purification Improvements

P. Gagnon, 2019 .

Chromatographic behavior of IgM:DNA complexes.

P. Gagnon, F. Hensel, S. Lee, 2011, Journal of chromatography. A.

Method for obtaining unique selectivities in ion-exchange chromatography by addition of organic polymers to the mobile phase

P. Gagnon, Bill Godfrey, D. Ladd, 1996 .

Self-assembly of lipopolysaccharide layers on allantoin crystals.

Vincent Vagenende, P. Gagnon, Tim-Jang Ching, 2014, Colloids and surfaces. B, Biointerfaces.

Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G.

Rui Nian, L. Tan, P. Gagnon, 2014, Journal of chromatography. A.

Multiple-Monitor HPLC Assays for Rapid Process Development, In-Process Monitoring, and Validation of AAV Production and Purification

P. Gagnon, Nina Mencin, Sebastijan Peljhan, 2021, Pharmaceutics.

Building Process Control into Chromatographic Purification of Viruses , Part 2 Purification As a Tool for Enhancing Process Control

P. Gagnon, D. Gavin, 2006 .

Advance chromatin extraction improves capture performance of protein A affinity chromatography.

Yuansheng Yang, Pete Gagnon, Rui Nian, 2016, Journal of chromatography. A.

Recent Advances in Endotoxin Removal An Upgrade to a Traditional Method and a New Adsorption Chemistry

P. Gagnon, 2017 .

Non-immunospecific association of immunoglobulin G with chromatin during elution from protein A inflates host contamination, aggregate content, and antibody loss.

Rui Nian, P. Gagnon, Yuansheng Yang, 2015, Journal of chromatography. A.

A tribute to Dr. Serge N. Timasheff, our mentor

G. Somero, T. Arakawa, R. Bhat, 2021, Biophysical Reviews.

Purification of monomeric mAb from associated aggregates using selective desorption chromatography in hydroxyapatite systems

S. Cramer, P. Gagnon, C. J. Morrison, 2011, Biotechnology and bioengineering.

Guanidine improves DEAE anion exchange‐based analytical separation of plasmid DNA

P. Gagnon, U. Černigoj, Nina Mencin, 2021, Electrophoresis.

IgG aggregate removal by charged-hydrophobic mixed mode chromatography.

Pete Gagnon, P. Gagnon, 2009, Current pharmaceutical biotechnology.

Excluded Cosolvent in Chromatography.

Pete Gagnon, T. Arakawa, P. Gagnon, 2018, Journal of pharmaceutical sciences.

Removal of empty capsids from adeno-associated virus preparations by multimodal metal affinity chromatography.

P. Gagnon, A. Raspor, Sebastijan Peljhan, 2021, Journal of chromatography. A.

Immunoglobulins M survive low-pH conditions used for virus inactivation and for elution from bioaffinity columns.

M. Bardor, Do Yun Kim, P. Gagnon, 2013, Journal of pharmaceutical sciences.

Unique selectivity windows using selective displacers/eluents and mobile phase modifiers on hydroxyapatite.

S. Cramer, P. Gagnon, C. J. Morrison, 2010, Journal of chromatography. A.

Transient conformational modification of immunoglobulin G during purification by protein A affinity chromatography.

Rui Nian, P. Gagnon, Aina Hoi, 2015, Journal of chromatography. A.

Use of Hydrophobic Interaction Chromatography with a Non-Salt Buffer System for Impr oving Process Economics in Purification of Monoclonal Antibodies

P. Gagnon, 2000 .

Improved antibody aggregate removal by hydroxyapatite chromatography in the presence of polyethylene glycol.

Pete Gagnon, P. Gagnon, 2008, Journal of immunological methods.

PURIFICATION OF MONOCLONAL ANTIBODIES BY MIXED‐MODE CHROMATOGRAPHY

Pete Gagnon, P. Gagnon, 2008 .

IgM Purification with Hydroxyapatite

W. Lau, P. Gagnon, Sarah Maria Abdul Latiff, 2014 .

Void exclusion of antibodies by grafted-ligand porous particle anion exchangers.

Rui Nian, Vincent Vagenende, P. Gagnon, 2013, Journal of chromatography. A.

Chromatographic purification with CIMmultus™ Oligo dT increases mRNA stability

M. Korenč, P. Gagnon, R. Sekirnik, 2021, Cell and Gene Therapy Insights.

Characterization of DNA in cell culture supernatant by fluorescence-detection size-exclusion chromatography

L. Tan, P. Gagnon, Yuansheng Yang, 2015, Analytical and Bioanalytical Chemistry.

Technology trends in antibody purification.

P. Gagnon, 2012, Journal of chromatography. A.

Large-scale process development for hydrophobic interaction chromatography. II: Controlling process variation

P. Gagnon, E. Grund, Torgny Lindbäck, 1995 .

Large-scale process development for hydrophobic interaction chromatography. I: Gel selection and development of binding conditions

P. Gagnon, P. Gagnon, E. Grund, 1995 .

Separation of Empty and Full Adeno-Associated Virus Capsids from a Weak Anion Exchanger by Elution with an Ascending pH Gradient at Low Ionic Strength

P. Gagnon, Blaž Goričar, A. Štrancar, 2021 .