Fabian Higel

发表

Small scale affinity purification and high sensitivity reversed phase nanoLC-MS N-glycan characterization of mAbs and fusion proteins

F. Sörgel, W. Friess, Andreas Seidl, 2014, mAbs.

N‐glycans of complex glycosylated biopharmaceuticals and their impact on protein clearance

F. Sörgel, W. Friess, Andreas Seidl, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Pharmacokinetic profiling of therapeutic proteins and variants by mass spectrometry

Fabian Higel, 2014 .

N-glycan PK Profiling Using a High Sensitivity nanoLCMS Work-Flow with Heavy Stable Isotope Labeled Internal Standard and Application to a Preclinical Study of an IgG1 Biopharmaceutical

F. Sörgel, W. Friess, U. Kronthaler, 2015, Pharmaceutical Research.

Shedding of glycan‐modifying enzymes by signal peptide peptidase‐like 3 (SPPL3) regulates cellular N‐glycosylation

R. Obst, B. Schröder, C. Haass, 2014, The EMBO journal.

N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins.

Wolfgang Friess, Fritz Sörgel, F. Sörgel, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The structure-function relationship of disulfide bonds in etanercept

J. Holzmann, C. Fritsch, Andreas Seidl, 2017, Scientific Reports.

Yersinia enterocolitica Infection and tcaA-Dependent Killing of Caenorhabditis elegans

T. Fuchs, S. Scherer, Fabian Higel, 2010, Applied and Environmental Microbiology.

Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals

F. Sörgel, W. Friess, Andreas Seidl, 2013, Analytical and Bioanalytical Chemistry.

Towards Maximum Acceleration of Monoclonal Antibody Development: Leveraging Transposase-Mediated Cell Line Generation to Enable GMP Manufacturing within 3 Months using a Stable Pool.

P. Schulz, Simon Fischer, Valerie Schmieder, 2022, Journal of biotechnology.

High-selectivity profiling of released and labeled N-glycans via polar-embedded reversed-phase chromatography

Fabian Higel, Marco Dehling, Johannes G. Wilhelm, 2018, Analytical and Bioanalytical Chemistry.

Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals

F. Sörgel, W. Friess, Andreas Seidl, 2013 .

N-glycan PK Profiling Using a High Sensitivity nanoLCMS Work-Flow with Heavy Stable Isotope Labeled Internal Standard and Application to a Preclinical Study of an IgG1 Biopharmaceutical

F. Sörgel, W. Friess, U. Kronthaler, 2015, Pharmaceutical Research.

N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins.

F. Sörgel, W. Friess, Andreas Seidl, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.