O. Ljunggren

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A TA-repeat polymorphism in the gene for the estrogen receptor alpha does not correlate with muscle strength or body composition in young adult Swedish women.

E. Grundberg, E. Ribom, H. Mallmin, 2005, Maturitas.

There is in elderly men a group difference between fallers and non-fallers in physical performance tests.

Ping Chung Leung, Claes Ohlsson, Mattias Lorentzon, 2011, Age and ageing.

Estimation of physical performance and measurements of habitual physical activity may capture men with high risk to fall--data from the Mr Os Sweden cohort.

Claes Ohlsson, Eric Orwoll, D. Mellström, 2009, Archives of gerontology and geriatrics.

Genetic variation in the human vitamin D receptor is associated with muscle strength, fat mass and body weight in Swedish women.

E. Grundberg, E. Ribom, H. Mallmin, 2004, European journal of endocrinology.

Low calcaneal bone mineral density and the risk of distal forearm fracture in women and men: a population-based case-control study.

D. Mellström, C. Ohlsson, H. Ahlborg, 2009, Bone.

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition.

David M. Evans, D. Kiel, A. Hofman, 2014, Bone.

A New fluorometric assay for determination of osteoblastic proliferation: Effects of glucocorticoids and insulin-like growth factor-I

S. Ljunghall, R. Larsson, O. Ljunggren, 2009, Calcified Tissue International.

Insulin-like growth factor I is a growth and survival factor in human multiple myeloma cell lines.

P. Georgii‐Hemming, K. Nilsson, O. Ljunggren, 1996, Blood.

Genetic Variants Associated with Circulating Fibroblast Growth Factor 23.

B. Kestenbaum, C. Robinson-Cohen, I. D. de Boer, 2018, Journal of the American Society of Nephrology : JASN.

Calcium and vitamin D for prevention of osteoporotic fractures

A. Avenell, B. Freyschuss, D. Mellstrom, 2007, The Lancet.

Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers.

H. Jüppner, T. Larsson, O. Ljunggren, 2003, Kidney international.

Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Reduced Serum Levels of the Growth Hormone- Dependent Insulin-Like Growth Factor Binding Protein and a Negative Bone Balance at the Level of Indiv

A. Lindahl, S. Ljunghall, W. Blum, 2022 .

Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia.

K. White, M. Econs, H. Jüppner, 2003, The New England journal of medicine.

Low serum testosterone and estradiol predict mortality in elderly men.

D. Mellström, C. Ohlsson, L. Vandenput, 2009, The Journal of clinical endocrinology and metabolism.

Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men. The MrOS Study in Sweden.

B. Fagerberg, B. Lernfelt, D. Mellström, 2007, Journal of the American College of Cardiology.

Associations of estradiol and testosterone with serum phosphorus in older men: the Osteoporotic Fractures in Men study.

E. Barrett-Connor, C. Ohlsson, M. Chonchol, 2010, Kidney international.

A Poly Adenosine Repeat in the Human Vitamin D Receptor Gene is Associated with Bone Mineral Density in Young Swedish Women

E. Grundberg, E. Ribom, H. Mallmin, 2003, Calcified Tissue International.

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

D. Mellström, C. Swanson, C. Ohlsson, 2007, The Journal of clinical endocrinology and metabolism.

The impact of estradiol on bone mineral density is modulated by the specific estrogen receptor-alpha cofactor retinoblastoma-interacting zinc finger protein-1 insertion/deletion polymorphism.

D. Mellström, C. Ohlsson, E. Grundberg, 2007, The Journal of clinical endocrinology and metabolism.

Disturbances of calcium homeostasis consistent with mild primary hyperparathyroidism in premenopausal women and associated morbidity.

J. Rastad, O. Ljunggren, E. Lundgren, 2008, The Journal of clinical endocrinology and metabolism.

Serum estradiol is associated with lean mass in elderly Swedish men.

D. Mellström, C. Ohlsson, L. Vandenput, 2010, European journal of endocrinology.

Osteoprotegerin secretion from prostate cancer is stimulated by cytokines, in vitro.

H. Brändström, O. Ljunggren, O. Nilsson, 2002, Biochemical and biophysical research communications.

Regulation of fibroblast growth factor-23 in chronic kidney disease.

M. Stridsberg, T. Larsson, O. Ljunggren, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells.

G. Åkerström, Tijana Krajisnik, G. Westin, 2007, The Journal of endocrinology.

Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis.

C. Ohlsson, H. Jüppner, T. Larsson, 2004, Endocrinology.

The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting.

T. Spector, T. Meitinger, T. Strom, 2001, The Journal of clinical endocrinology and metabolism.

Studies on two new vitamin D analogs, EB 1089 and KH 1060: effects on bone resorption and osteoclast recruitment in vitro.

L. Binderup, S. Ljunghall, O. Ljunggren, 1995, Bone.

Tumor necrosis factor-alpha and -beta upregulate the levels of osteoprotegerin mRNA in human osteosarcoma MG-63 cells.

C. Ohlsson, S. Ljunghall, H. Brändström, 1998, Biochemical and biophysical research communications.

Osteoprotegerin mRNA is increased by interleukin-1 alpha in the human osteosarcoma cell line MG-63 and in human osteoblast-like cells.

K. Sjögren, C. Ohlsson, B. Eriksson, 1998, Biochemical and biophysical research communications.

Regulation of osteoprotegerin mRNA levels by prostaglandin E2 in human bone marrow stroma cells.

C. Ohlsson, S. Ljunghall, H. Brändström, 1998, Biochemical and biophysical research communications.

Immunohistochemical detection of FGF-23 protein in tumors that cause oncogenic osteomalacia.

H. Jüppner, R. Zahradnik, J. Lavigne, 2003, European journal of endocrinology.

Use of a Swedish T-score reference population for women causes a two-fold increase in the amount of postmenopausal Swedish patients that fulfill the WHO criteria for osteoporosis.

E. Ribom, H. Mallmin, O. Ljunggren, 2008, Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry.

Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells.

T. Björkman, H. Brändström, Ö. Ljunggren, 2001, Biochemical and biophysical research communications.

Heterozygosity for a coding SNP in COL1A2 confers a lower BMD and an increased stroke risk.

D. Mellström, C. Ohlsson, C. Rubin, 2009, Biochemical and biophysical research communications.

Three isolation techniques for primary culture of human osteoblast-like cells: a comparison.

S. Ljunghall, O. Ljunggren, O. Nilsson, 1999, Acta orthopaedica Scandinavica.

Interleukin-13 inhibits cell proliferation and stimulates interleukin-6 formation in isolated human osteoblasts.

C. Ohlsson, S. Ljunghall, H. Brändström, 1998, The Journal of clinical endocrinology and metabolism.

Interleukin (IL)-13 and IL-4 inhibit proliferation and stimulate IL-6 formation in human osteoblasts: evidence for involvement of receptor subunits IL-13R, IL-13Ralpha, and IL-4Ralpha.

S. Ljunghall, H. Brändström, Ö. Ljunggren, 2001, Bone.

Population genomics in a disease targeted primary cell model.

Daniel Sinnett, Fernando Rivadeneira, Claes Ohlsson, 2009, Genome research.

Interleukin-1 beta induces cyclic AMP formation in isolated human osteoblasts: a signalling mechanism that is not related to enhanced prostaglandin formation.

S. Ljunghall, K. Nilsson, O. Ljunggren, 1994, Bone and mineral.

Preoperative tumor localization by means of venous sampling for fibroblast growth factor-23 in a patient with tumor-induced osteomalacia.

H. Olauson, T. Larsson, O. Ljunggren, 2008, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23.

C. Ohlsson, H. Göransson, Tijana Krajisnik, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Fibroblast growth factor-23 is associated with parathyroid hormone and renal function in a population-based cohort of elderly men.

D. Mellström, C. Ohlsson, E. Grundberg, 2008, European journal of endocrinology.

Prostaglandin E 2 Causes a Transient Inhibition of Mineral Mobilization , Matrix Degradation , and Lysosomal Enzyme Release from Mouse Calvarial Bones In Vitro

U. Lerner, O. Ljunggren, M. Ransjo, 2022 .

Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts.

B. Fredholm, S. Ljunghall, U. Lerner, 1993, European journal of pharmacology.

On the role of polyamines in bone resorption induced by parathyroid hormone.

B. Fredholm, U. Lerner, O. Ljunggren, 1991, Acta physiologica Scandinavica.

Diagnosis of a patient with oncogenic osteomalacia using a phosphate uptake bioassay of serum and magnetic resonance imaging.

J. Hogan, R. Mason, G. Åström, 2001, European journal of endocrinology.

Fibroblast growth factor-23 and mineral metabolism after unilateral nephrectomy.

T. Larsson, J. Wadström, O. Ljunggren, 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Systematic assessment of the human osteoblast transcriptome in resting and induced primary cells.

T. Pastinen, B. Ge, E. Harmsen, 2008, Physiological genomics.

Inflammatory cytokines regulate proliferation of cultured human osteoblasts.

O. Ljunggren, O. Nilsson, K. Jonsson, 1997, Acta orthopaedica Scandinavica.

Effectiveness of Teriparatide in Women Over 75 Years of Age with Severe Osteoporosis: 36-Month Results from the European Forsteo Observational Study (EFOS)

W. Lems, J. Walsh, A. Fahrleitner-Pammer, 2012, Calcified Tissue International.

Comparison of human interleukin-1 beta and its 163-171 peptide in bone resorption and the immune response.

F. Dewhirst, U. Lerner, D. Boraschi, 1991, Cytokine.

Stimulation of bone resorption in cultured mouse calvaria by Lys-bradykinin (kallidin), a potential mediator of bone resorption linking anaphylaxis processes to rarefying osteitis.

P. Boonekamp, U. Lerner, O. Ljunggren, 1986, Bone and mineral.

Bradykinin stimulates production of prostaglandin E2 and prostacyclin in murine osteoblasts.

U. Lerner, O. Ljunggren, M. Ransjö, 1989, Bone and mineral.

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.

D. Kiel, A. Hofman, A. Uitterlinden, 2014, Human molecular genetics.

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis.

D. Kiel, A. Hofman, A. Uitterlinden, 2008, JAMA.

Stimulation of bone resorption in cultured mouse calvaria by met-lys-bradykinin.

U. Lerner, O. Ljunggren, 1988, Journal of periodontal research.

A deletion polymorphism in the RIZ gene, a female sex steroid hormone receptor coactivator, exhibits decreased response to estrogen in vitro and associates with low bone mineral density in young Swedish women.

E. Grundberg, E. Ribom, T. Carling, 2004, The Journal of clinical endocrinology and metabolism.

Effects of teriparatide in postmenopausal women with osteoporosis pre-treated with bisphosphonates: 36-month results from the European Forsteo Observational Study

W. Lems, F. Jakob, J. Walsh, 2012, European Journal of Endocrinology.

Effects of teriparatide in postmenopausal women with osteoporosis pre-treated with bisphosphonates: 36-month results from the European Forsteo Observational Study

W. Lems, F. Jakob, J. Walsh, 2012, European journal of endocrinology.

Alendronate/vitamin D3 70 mg/2800 IU with and without additional 2800 IU vitamin D3 for osteoporosis: results from the 24-week extension of a 15-week randomized, controlled trial.

M. Holick, N. Binkley, H. Minne, 2009, Bone.

Addressing the Musculoskeletal Components of Fracture Risk with Calcium and Vitamin D: A Review of the Evidence

C. Cooper, S. Boonen, H. Bischoff-Ferrari, 2006, Calcified Tissue International.

Rats treated with AZD2858, a GSK3 inhibitor, heal fractures rapidly without endochondral bone formation.

S. Larsson, O. Ljunggren, O. Nilsson, 2013, Bone.

GSK-3 inhibition by an orally active small molecule increases bone mass in rats.

U. Andersson, S. Larsson, O. Ljunggren, 2012, Bone.

Thrombin, but not bradykinin, stimulates proliferation in isolated human osteoblasts, via a mechanism not dependent on endogenous prostaglandin formation.

S. Ljunghall, P. Ridefelt, O. Ljunggren, 1999, Acta orthopaedica Scandinavica.

Bone resorption induced by A23187 is abolished by indomethacin: implications for second messenger utilised by parathyroid hormone.

S. Ljunghall, O. Ljunggren, E. Bornefalk, 1998, European journal of pharmacology.

High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. The MrOS (Osteoporotic Fractures in Men) study in Sweden.

E. Barrett-Connor, D. Mellström, C. Ohlsson, 2011, Journal of the American College of Cardiology.

Thrombin increases cytoplasmic Ca2+ and stimulates formation of prostaglandin E2 in the osteoblastic cell line MC3T3-El.

S. Ljunghall, U. Lerner, O. Ljunggren, 1991, Bone and mineral.

Androgens and glucuronidated androgen metabolites are associated with metabolic risk factors in men.

L. Lönn, D. Mellström, C. Swanson, 2007, The Journal of clinical endocrinology and metabolism.

Serum insulin-like growth factor-I concentration is associated with leukocyte telomere length in a population-based cohort of elderly men.

D. Mellström, S. Movérare-Skrtic, C. Ohlsson, 2009, The Journal of clinical endocrinology and metabolism.

Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.

S. Cummings, A. Syvänen, D. Mellström, 2009, The Journal of clinical endocrinology and metabolism.

Six months of hormone replacement therapy does not influence muscle strength in postmenopausal women.

E. Ribom, S. Ljunghall, K. Piehl-Aulin, 2002, Maturitas.

Low body mass index and use of corticosteroids, but not cholestasis, are risk factors for osteoporosis in patients with chronic liver disease.

H. Mallmin, O. Ljunggren, L. Lööf, 1999, Journal of hepatology.

Risk of imminent fracture following a previous fracture in a Swedish database study

K. Åkesson, Ö. Ljunggren, O. Ljunggren, 2019, Osteoporosis International.

Inferior physical performance test results of 10,998 men in the MrOS Study is associated with high fracture risk.

E. Barrett-Connor, D. Mellström, C. Ohlsson, 2012, Age and ageing.

The COMT val158met polymorphism is associated with prevalent fractures in Swedish men.

I. Redlund‐Johnell, D. Mellström, C. Ohlsson, 2008, Bone.

Parathyroid hormone is able to enhance cyclic adenosine monophosphate formation without causing an increase in cytoplasmic Ca2+ in osteoblasts.

S. Ljunghall, U. Lerner, P. Ridefelt, 1993, Acta endocrinologica.

Haptoglobin synergistically potentiates bradykinin and thrombin induced prostaglandin biosynthesis in isolated osteoblasts.

U. Lerner, O. Ljunggren, N. Fröhlander, 1991, Biochemical and biophysical research communications.

Allele-specific gene silencing in osteogenesis imperfecta.

C. Rubin, A. Kindmark, O. Ljunggren, 2011, Endocrine development.

Effectiveness of Teriparatide in Women Over 75 Years of Age with Severe Osteoporosis: 36-Month Results from the European Forsteo Observational Study (EFOS)

W. Lems, F. Jakob, J. Walsh, 2012, Calcified Tissue International.

Bradykinin-2 receptor-mediated release of 3H-arachidonic acid and formation of prostaglandin E2 in human gingival fibroblasts.

U. Lerner, O. Ljunggren, T. Modéer, 1990, Journal of periodontal research.

Thrombin and bradykinin enhance prostaglandin production in human peripheral blood monocytes.

U. Lerner, O. Ljunggren, K. Sahlberg, 1989, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Forskolin sensitizes parathyroid hormone-induced cyclic AMP response, but not the bone resorptive effect, in mouse calvarial bones.

B. Fredholm, U. Lerner, O. Ljunggren, 1989, Bone and mineral.

Low serum levels of dehydroepiandrosterone sulfate predict all-cause and cardiovascular mortality in elderly Swedish men.

E. Barrett-Connor, D. Mellström, C. Ohlsson, 2010, The Journal of clinical endocrinology and metabolism.

Ga3+ inhibits parathyroid hormone release without interacting with the Ca2+ receptor of the parathyroid cell.

J. Rastad, G. Åkerström, S. Ljunghall, 1992, Biochemical and biophysical research communications.

Parathyroid hormone stimulates prostanoid formation in mouse calvarial bones.

U. Lerner, O. Ljunggren, 1989, Acta endocrinologica.

Serum estradiol is associated with lean mass in elderly Swedish men.

D. Mellström, C. Ohlsson, L. Vandenput, 2010, European journal of endocrinology.

Regulation of fibroblast growth factor-23 in chronic kidney disease.

M. Stridsberg, T. Larsson, O. Ljunggren, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis.

D. Kiel, J. V. van Meurs, J. Ioannidis, 2008, JAMA.