J. Lafaille

发表

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

D. Littman, Liang Zhou, I. Ivanov, 2006, Cell.

Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?

M. A. Curotto de Lafaille, J. Lafaille, Maria A Curotto de Lafaille, 2009, Immunity.

Maternal-Fetal Immune Tolerance, Block by Block

J. Lafaille, M. Gobert, 2012, Cell.

Interleukin 2 Signaling Is Required for CD4+ Regulatory T Cell Function

J. Lafaille, G. Furtado, Gláucia C. Furtado, 2002, The Journal of experimental medicine.

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

Michael Loran Dustin, Yi Ding, A. Lino, 2006, The Journal of experimental medicine.

Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis.

M. A. Curotto de Lafaille, H. Fox, M. Marcondes, 2005, The American journal of pathology.

Control of homeostatic proliferation by regulatory T cells.

M. A. Curotto de Lafaille, C. Tadokoro, J. Lafaille, 2005, The Journal of clinical investigation.

CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion1

M. A. Curotto de Lafaille, A. Lino, J. Lafaille, 2004, The Journal of Immunology.

Regulatory T Cells by Peripheral Expansion + Foxp 3 + T Cells Generate CD 25 − CD 25 Kutchukhidze and

A. Lino, J. Lafaille, M. Lafaille, 2004 .

The role of regulatory T cells in allergy

M. A. Curotto de Lafaille, J. Lafaille, 2004, Springer Seminars in Immunopathology.

CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis.

S. Tonegawa, T. Mak, J. Penninger, 1999, Journal of immunology.

Hyper Immunoglobulin E Response in Mice with Monoclonal Populations of B and T Lymphocytes 〉

Y. Lei, M. Sunshine, J. Lafaille, 2001, The Journal of experimental medicine.

Regulatory T cells in spontaneous autoimmune encephalomyelitis

M. A. Curotto de Lafaille, J. Lafaille, Jo-Ann M. Latkowski, 2001, Immunological reviews.

A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions

J. Buxbaum, J. Schlessinger, M. Chao, 2002, Nature Genetics.

Against Liver Stages of Murine Malaria T Cell Responses + the Magnitude of CD8 Early Self-Regulatory Mechanisms Control

G. Milon, A. Morrot, J. Lafaille, 2003 .

Early Self-Regulatory Mechanisms Control the Magnitude of CD8+ T Cell Responses Against Liver Stages of Murine Malaria1

G. Milon, A. Morrot, J. Lafaille, 2003, The Journal of Immunology.

Early Self-Regulatory Mechanisms Control

G. Milon, A. Morrot, J. Lafaille, 2003 .

Focused Specificity of Intestinal Th17 Cells towards Commensal Bacterial Antigens

Jonathan L. Linehan, D. Littman, Yi Yang, 2014, Nature.

Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges

K. Cadwell, H. M. Silva, P. Cohen, 2019, The Journal of experimental medicine.

Vasculature-associated adipose tissue macrophages dynamically adapt to inflammatory and metabolic challenges

K. Cadwell, H. M. Silva, P. Cohen, 2018, bioRxiv.

Unique maturation program of the IgE response in vivo.

M. A. Curotto de Lafaille, J. Urban, J. Lafaille, 2007, Immunity.

Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system

X. Chen, L. Chess, A. Schmidt, 2003, Nature Medicine.

PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner

Chuan-ju Liu, Yuying Zhang, Wei Tang, 2014, Scientific Reports.

Interleukin 2 Signaling Is Required for CD4 (cid:2) Regulatory T Cell Function

J. Lafaille, G. Furtado, M. Lafaille, 2002 .

The T cell receptor repertoire of intestinal intraepithelial gammadelta T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci.

S. Tonegawa, P. Pereira, D. Gerber, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Diversity, Development, Ligands, and Probable Functions of γδ T Cells

S. Tonegawa, S. Itohara, C. Janeway, 1989 .

Peripheral expansion of thymus‐derived regulatory cells in anti‐myelin basic protein T cell receptor transgenic mice

A. Coutinho, M. Haury, J. Demengeot, 2002, European journal of immunology.

Homing of a gamma delta thymocyte subset with homogeneous T-cell receptors to mucosal epithelia.

S. Tonegawa, S. Itohara, M. Bonneville, 1990, Nature.

The Role of IFN-γ in the Production of Th2 Subpopulations: Implications for Variable Th2-Mediated Pathologies in Autoimmunity1

J. Lafaille, A. Wensky, Maria Cecília Garibaldi Marcondes, 2001, The Journal of Immunology.

The role of helper T cell subsets in autoimmune diseases.

J. Lafaille, 1998, Cytokine & growth factor reviews.

Mechanisms of tolerance and allergic sensitization in the airways and the lungs.

M. A. Curotto de Lafaille, L. Graça, J. Lafaille, 2010, Current opinion in immunology.

Swift Development of Protective Effector Functions in Naive Cd8+ T Cells against Malaria Liver Stages

R. Abe, A. Morrot, J. Lafaille, 2001, The Journal of experimental medicine.

A Developmental Role for Microglial Presenilin 1 in Memory

P. Greengard, J. Friedman, B. Stevens, 2021, bioRxiv.

IFN-γ Determines Distinct Clinical Outcomes in Autoimmune Encephalomyelitis1

Shaohua Chen, D. Zagzag, S. Lira, 2005, The Journal of Immunology.

IFN-gamma determines distinct clinical outcomes in autoimmune encephalomyelitis.

Shaohua Chen, D. Zagzag, S. Lira, 2005, Journal of immunology.

Tissue adaptation of regulatory and intraepithelial CD4+ T cells controls gut inflammation

H. M. Silva, T. Buch, J. Lafaille, 2016, Science.

Immunological Yin-Yang

D. Mathis, J. Lafaille, 2002 .

Th 2-Mediated Pathologies in Autoimmunity Subpopulations : Implications for Variable in the Production of Th 2 γ The Role of IFN-J .

M. Marcondes, J. Lafaille, A. Wensky, 2001 .

EncephalomyelitisDevelopment of Spontaneous Autoimmune CD28 Costimulation Is Crucial for the

S. Tonegawa, T. Mak, J. Penninger, 1999 .

Lipid phosphate phosphatase 3 enables efficient thymic egress

R. Adams, A. Morris, J. Lafaille, 2011, The Journal of experimental medicine.

T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes.

S. Tonegawa, S. Itohara, P. Mombaerts, 1993, Cell.

Characterization of Two Distinct Lymphoproliferative Diseases Caused by Ectopic Expression of the Notch Ligand DLL4 on T Cells

Jie Shen, C. Tadokoro, J. Lafaille, 2013, PloS one.

c-MAF–dependent perivascular macrophages regulate diet-induced metabolic syndrome

D. Littman, M. Bozza, J. Lafaille, 2021, Science Immunology.

c-MAF dependent perivascular macrophages regulate diet induced metabolic syndrome

D. Littman, M. Bozza, H. M. Silva, 2021, bioRxiv.

Structure and expression of two Trypanosoma cruzi genes encoding antigenic proteins bearing repetitive epitopes.

J. Linss, S. Goldenberg, W. de Souza, 1989, Molecular and biochemical parasitology.

Cutting Edge: Intrathymic Differentiation of Adaptive Foxp3+ Regulatory T Cells upon Peripheral Proinflammatory Immunization

S. Zelenay, J. Demengeot, M. Bergman, 2010, The Journal of Immunology.

Peripheral Proinflammatory Immunization Regulatory T Cells upon + Adaptive Foxp3 Cutting Edge: Intrathymic Differentiation of

S. Zelenay, J. Demengeot, M. Bergman, 2022 .

Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells.

M. Serrano, M. Badura, Jie Shen, 2007, Blood.

Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8 (cid:1) T cells

M. Serrano, M. Badura, C. Tadokoro, 2007 .

Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

S. Tonegawa, C. Raine, J. Lafaille, 1997, The Journal of experimental medicine.

Adjuvant facilitates tolerance induction to factor VIII in hemophilic mice through a Foxp3-independent mechanism that relies on IL-10.

M. A. Curotto de Lafaille, V. Oliveira, L. Graça, 2013, Blood.

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

Susumu Tonegawa, S. Tonegawa, M. Katsuki, 1994, Cell.

Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23.

J. Faith, R. DeVita, S. Lira, 2021, Cell metabolism.

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

Dan R. Littman, Maria Ciofani, Fabio R. Santori, 2011, Nature.

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

D. Littman, Liang Zhou, I. Ivanov, 2006, Cell.

Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites.

R. Ransohoff, Michael Loran Dustin, Jiyun V Kim, 2010, Journal of immunological methods.

Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia

S. Tonegawa, S. Itohara, M. Bonneville, 1990, Nature.

Induced CD4+Foxp3+ regulatory T cells in immune tolerance.

J. Lafaille, Angelina M. Bilate, 2012, Annual review of immunology.

Diet Modifies Colonic Microbiota and CD4+ T-Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-Cell Expression of Interleukin 23.

R. Sachidanandam, J. Clemente, J. Faith, 2018, Gastroenterology.

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

J. Yates, W. Gan, Guang Yang, 2013, Cell.

CD4(+) regulatory T cells in autoimmunity and allergy.

M. A. Curotto de Lafaille, J. Lafaille, Maria A Curotto de Lafaille, 2002, Current opinion in immunology.

Trypanosoma Cruzi Flagellar Repetitive Antigen Expression by Recombinant Baculovirus: Towards an Improved Diagnostics Reagent for Chagas' Disease

S. Goldenberg, M. Krieger, J. Lafaille, 1992, Bio/Technology.

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

S. Tonegawa, M. Rudnicki, R. Jaenisch, 1992, Nature.

Single-Cell RNA Sequencing of Visceral Adipose Tissue Leukocytes Reveals that Caloric Restriction Following Obesity Promotes the Accumulation of a Distinct Macrophage Population with Features of Phagocytic Cells

K. Moore, E. Fisher, Ada Weinstock, 2019, Immunometabolism.

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages.

M. Rudnicki, R. Jaenisch, S. Itohara, 1992, Nature.

CD3δ deficiency arrests development of the αβ but not the γδ T cell lineage

S. Tonegawa, B. Alarcón, A. De La Hera, 1997 .

Transcriptomic analysis of loss of Gli1 in neural stem cells responding to demyelination in the mouse brain

J. Salzer, H. M. Silva, J. Lafaille, 2021, Scientific Data.

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

R. Satija, D. Littman, A. Kimmelman, 2019, Cell.

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

R. Satija, D. Littman, A. Kimmelman, 2019, Cell.

T-cell receptor transgenic mice in the study of autoimmune diseases.

J. Lafaille, 2004, Journal of autoimmunity.

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

J. Weiss, A. Rudensky, Michael Loran Dustin, 2012, The Journal of experimental medicine.

Regulatory T Cells in Immune Tolerance

J. Lafaille, Angelina M. Bilate, 2012 .

Use of recombinant antigens for the accurate immunodiagnosis of Chagas' disease.

S. Goldenberg, M. Krieger, J. Lafaille, 1992, The American journal of tropical medicine and hygiene.

Latent TGF‐β1‐transduced CD4+ T cells suppress the progression of allergic encephalomyelitis

J. Salzer, M. Murano, J. Lafaille, 2006, Journal of leukocyte biology.

Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

Sudha Kumari, S. Abramson, Michael Loran Dustin, 2012, Proceedings of the National Academy of Sciences.

Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining

Susumu Tonegawa, Marc Bonneville, S. Tonegawa, 1989, Cell.

Multifaceted influence of pre-mitotic cytotoxicity of primed CD8 T cells on immunity and infection

Michael Loran Dustin, V. Mayya, J. Lafaille, 2018 .

Positive selection of γδ T cells

S. Tonegawa, A. Coutinho, J. Lafaille, 1990 .

Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination

G. Fishell, J. Salzer, H. M. Silva, 2015, Nature.

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

Susumu Tonegawa, Shigeyoshi Itohara, Alan R. Clarke, 1993, Cell.

Biology of IgE production: IgE cell differentiation and the memory of IgE responses.

Sriram Narayanan, W. Ho, M. A. Curotto de Lafaille, 2015, Current topics in microbiology and immunology.

It takes two to tango.

J. Lafaille, Angelina M. Bilate, 2011, Immunity.

Sequential class switching is required for the generation of high affinity IgE antibodies

M. Wabl, M. A. Curotto de Lafaille, J. Lafaille, 2012, The Journal of experimental medicine.

Protein Kinase C-θ Mediates Negative Feedback on Regulatory T Cell Function

Sudha Kumari, S. Abramson, Michael Loran Dustin, 2010, Science.

Increased generation of Foxp3+ regulatory T cells by manipulating antigen presentation in the thymus

Michael Loran Dustin, Yongwon Choi, H. M. Silva, 2016, Nature Communications.

Do Regulatory T Cells Play a Role in the Control of Homeostatic Proliferation?

J. Lafaille, D. Olivares-Villagómez, Shiqian Shen, 2005, International reviews of immunology.

TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizes

J. Lafaille, Shiqian Shen, M. Leung, 2009, The Journal of experimental medicine.

A subpopulation of high IL-21-producing CD4+ T cells in Peyer’s Patches is induced by the microbiota and regulates germinal centers

K. Srinivasan, K. Honda, W. Ho, 2016, Scientific Reports.

Regulatory Cd4 Ϩ T Cells Expressing Endogenous T Cell Receptor Chains Protect Myelin Basic Protein–specific Transgenic Mice from Spontaneous Autoimmune Encephalomyelitis

J. Lafaille, D. Olivares-Villagómez, Yijie Wang, 1998 .

Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression

K. Moore, P. Loke, E. Fisher, 2020, Circulation research.

Oral tolerance in the absence of naturally occurring Tregs.

M. A. Curotto de Lafaille, M. Russo, J. Lafaille, 2005, The Journal of clinical investigation.

Route of Antigen Presentation Can Determine the Selection of Foxp3-Dependent or Foxp3-Independent Dominant Immune Tolerance

J. Demengeot, V. Oliveira, L. Graça, 2018, The Journal of Immunology.

CX3CR1+ monocytes modulate learning and learning-dependent dendritic spine remodeling via TNFα

Guang Yang, H. M. Silva, J. M. Garré, 2017, Nature Medicine.

The Orphan Nuclear Receptor ROR g t Directs the Differentiation Program of Proinflammatory IL-17 + T Helper Cells

D. Littman, Liang Zhou, I. Ivanov, 2014 .

CSF1R Inhibition Depletes Tumor-Associated Macrophages and Attenuates Tumor Progression in a Mouse Sonic Hedgehog-Medulloblastoma Model

A. Joyner, M. Merad, D. Turnbull, 2020, Oncogene.

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

Yi Ding, A. Lino, J. Lafaille, 2008, Nature Medicine.

The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate.

A. Morris, Manjula Sunkara, J. Lafaille, 2012, Cell reports.

What is unique about the IgE response?

M. A. Curotto de Lafaille, J. Lafaille, Huizhong Xiong, 2012, Advances in immunology.

The Biology of IgE: The Generation of High-Affinity IgE Antibodies

J. Lafaille, M. Lafaille, 2010 .

P2X7 receptor inhibition ameliorates dendritic spine pathology and social behavioral deficits in Rett syndrome mice

H. M. Silva, J. M. Garré, J. Lafaille, 2020, Nature Communications.

Corrigendum: A subpopulation of high IL-21-producing CD4+ T cells in Peyer’s Patches is induced by the microbiota and regulates germinal centers

K. Srinivasan, K. Honda, W. Ho, 2016, Scientific reports.

Repertoire Requirements of CD4+ T Cells That Prevent Spontaneous Autoimmune Encephalomyelitis1

J. Lafaille, D. Olivares-Villagómez, A. Wensky, 2000, The Journal of Immunology.

Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation.

H. Yee, M. A. Curotto de Lafaille, Yi Ding, 2008, Immunity.

IgE Antibodies: Generation and Function

J. Lafaille, M. Lafaille, 2015, Current Topics in Microbiology and Immunology.

Diet Modifies Colonic Microbiota and CD4+ T Cell Repertoire to Trigger Flares in a Novel Model of Colitis Induced by IL-23

R. Sachidanandam, J. Clemente, J. Faith, 2018, bioRxiv.

Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.

S. Tonegawa, M. Bonneville, J. Lafaille, 1989, Cell.

The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response

Sriram Narayanan, M. A. Curotto de Lafaille, M. Meyer-Hermann, 2013, The Journal of experimental medicine.

Swift Entry of Myelin-Specific T Lymphocytes into the Central Nervous System in Spontaneous Autoimmune Encephalomyelitis1

J. Lafaille, G. Furtado, A. Wensky, 2008, The Journal of Immunology.

Learning‐dependent dendritic spine plasticity is impaired in spontaneous autoimmune encephalomyelitis

Guang Yang, J. Lafaille, Lianyan Huang, 2021, Developmental neurobiology.

Can TNF-α boost regulatory T cells?

J. Lafaille, Angelina M. Bilate, 2010, The Journal of clinical investigation.

Spleen plays a major role in DLL4-driven acute T-cell lymphoblastic leukemia

Hossein Khiabanian, D. Herranz, G. Gómez-López, 2021, Theranostics.

IgG1 memory B cells keep the memory of IgE responses

K. Srinivasan, V. Narang, M. A. Curotto de Lafaille, 2017, Nature Communications.

Corrigendum: A subpopulation of high IL-21-producing CD4+ T cells in Peyer’s Patches is induced by the microbiota and regulates germinal centers

K. Srinivasan, K. Honda, W. Ho, 2016, Scientific Reports.

P2X7 receptor inhibition ameliorates dendritic spine pathology and social behavioral deficits in Rett syndrome mice

Guang Yang, H. M. Silva, J. M. Garré, 2020, Nature Communications.

Cloning of Trypanosoma cruzi stage specific genes

S. Aymerich, J. Linss, S. Goldenberg, 1987 .

The Orphan Nuclear Receptor ROR g t Directs the Differentiation Program of Proinﬂammatory IL-17 + T Helper Cells

D. Littman, I. Ivanov, B. McKenzie, 2022 .

CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.

S. Tonegawa, B. Alarcón, A. De La Hera, 1997, The EMBO journal.

On the differentiation of mouse IgE+ cells

J. Lafaille, Huizhong Xiong, M. Lafaille, 2012, Nature Immunology.

Pillars article: High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell. 1994. 78: 399-408.

S. Tonegawa, M. Katsuki, K. Nagashima, 2013, Journal of immunology.

Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?

M. A. Curotto de Lafaille, J. Lafaille, 2009, Immunity.

Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites.

R. Ransohoff, Michael Loran Dustin, Liping Liu, 2010, Journal of immunological methods.

Mechanisms of tolerance and allergic sensitization in the airways and the lungs.

M. A. Curotto de Lafaille, L. Graça, J. Lafaille, 2010, Current Opinion in Immunology.

Regulatory CD4+ T Cells Expressing Endogenous T Cell Receptor Chains Protect Myelin Basic Protein–specific Transgenic Mice from Spontaneous Autoimmune Encephalomyelitis

J. Lafaille, Yijie Wang, Danyvid Olivares-Villagómez, 1998, The Journal of experimental medicine.

Can TNF-α boost regulatory T cells?

J. Lafaille, Angelina M. Bilate, 2010, The Journal of clinical investigation.

Diversity, development, ligands, and probable functions of gamma delta T cells.

S. Tonegawa, S. Itohara, M. Katsuki, 1989, Cold Spring Harbor symposia on quantitative biology.

This information is current as Encephalomyelitis That Prevent Spontaneous Autoimmune T Cells + Repertoire Requirements of CD 4

J. Lafaille, Allen K. Wensky, Danyvid Olivares-Villagómez, 2000 .