Haiquan Lu

发表

Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment.

G. Semenza, Haiquan Lu, Ivan Chen, 2017, Cell reports.

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

Chuanzhao Zhang, Xiaoshun He, G. Semenza, 2016, Proceedings of the National Academy of Sciences.

ASCT2 (SLC1A5) is an EGFR-associated protein that can be co-targeted by cetuximab to sensitize cancer cells to ROS-induced apoptosis.

Z. Fan, Yang Lu, Haiquan Lu, 2016, Cancer letters.

β-Adrenergic Receptors : New Target in Breast Cancer.

L. Cai, Haiquan Lu, Qing-wei Meng, 2016, Asian Pacific journal of cancer prevention : APJCP.

Comprehensive analysis of FRAS1/FREM family as potential biomarkers and therapeutic targets in renal clear cell carcinoma

Haiquan Lu, Liqiang Guo, F. Kong, 2022, Frontiers in Pharmacology.

NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification

G. Semenza, Wenxin Qin, E. Datan, 2022, Science advances.

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells

G. Semenza, Daniele M. Gilkes, J. Bullen, 2015, Proceedings of the National Academy of Sciences.

Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness.

G. Semenza, J. Lan, Haiquan Lu, 2020, The Journal of clinical investigation.

Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

Chuanzhao Zhang, G. Semenza, E. Gabrielson, 2016, Oncotarget.

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

G. Semenza, Hongxia Hu, J. Bullen, 2015, Proceedings of the National Academy of Sciences.

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

G. Semenza, Daniele M. Gilkes, Hongxia Hu, 2014, Oncotarget.

Novel Functions of Cetuximab in EGFR-targeted Therapy: Radiosensitization, Glycolysis Inhibition, and Cellular Redox Status Regulation

Haiquan Lu, 2013 .

Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.

G. Semenza, J. Lan, Haiquan Lu, 2018, Cancer research.

HIF-1 recruits NANOG as a coactivator for TERT gene transcription in hypoxic breast cancer stem cells.

G. Semenza, J. Lan, Haiquan Lu, 2021, Cell reports.

Chemotherapy-induced adenosine A2B receptor expression mediates epigenetic regulation of pluripotency factors and promotes breast cancer stemness

Fan Yang, J. Lan, Haiquan Lu, 2022, Theranostics.

1, 9-Pyrazoloanthrones Downregulate HIF-1α and Sensitize Cancer Cells to Cetuximab-Mediated Anti-EGFR Therapy

Yang Lu, Haiquan Lu, Xinqun Li, 2010, PloS one.

HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia

G. Semenza, Haiquan Lu, Yongkang Yang, 2022, Nature Communications.

HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia

R. Cole, G. Semenza, Haiquan Lu, 2022, Nature communications.

Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization

G. Semenza, Qiuran Xu, Haiquan Lu, 2021, Science advances.

Establishment and validation of a carbohydrate metabolism-related gene signature for prognostic model and immune response in acute myeloid leukemia

You Yang, Jing Liu, Wenjun Liu, 2022, Frontiers in Immunology.

Rational combination with PDK1 inhibition overcomes cetuximab resistance in head and neck squamous cell carcinoma.

Z. Fan, Yang Lu, Haiquan Lu, 2019, JCI insight.

Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment

G. Semenza, J. Lan, Haiquan Lu, 2018, Proceedings of the National Academy of Sciences.

The anti-EGFR antibody cetuximab sensitizes human head and neck squamous cell carcinoma cells to radiation in part through inhibiting radiation-induced upregulation of HIF-1α.

K. Liang, Z. Fan, Yang Lu, 2012, Cancer letters.

Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis

G. Semenza, Daniele M. Gilkes, Haiquan Lu, 2021, Proceedings of the National Academy of Sciences.

Cetuximab Reverses the Warburg Effect by Inhibiting HIF-1–Regulated LDH-A

Z. Fan, Haiquan Lu, Zhongguang Luo, 2013, Molecular Cancer Therapeutics.

Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment.

G. Semenza, Haiquan Lu, Ivan Chen, 2021, Cell reports.

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab

Yang Lu, Z. Fan, Yang Lu, 2015, Oncotarget.

A Meta-Analysis of Lymphatic Vessel Invasion Correlated with Pathologic Factors in Invasive Breast Cancer

Gaofang Xiao, Haiquan Lu, Shizhen Zhong, 2015 .

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab

Z. Fan, Yang Lu, Haiquan Lu, 2015, OncoTarget.

The anti-EGFR antibody cetuximab sensitizes human head and neck squamous cell carcinoma cells to radiation in part through inhibiting radiation-induced upregulation of HIF-1α.

K. Liang, Z. Fan, Yang Lu, 2012, Cancer letters.

Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes.

G. Semenza, Haiquan Lu, Shaima Salman, 2024, Cell reports.