Douglas K. Brubaker

发表

Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth.

M. Chance, B. Jacobsson, L. Muglia, 2016, Human molecular genetics.

Substrate-based kinase activity inference identifies MK2 as driver of colitis.

Samantha Dale Strasser, Brian A. Joughin, D. Lauffenburger, 2019, Integrative biology : quantitative biosciences from nano to macro.

Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor†,‡

M. Chance, Sean Maxwell, Douglas K. Brubaker, 2018, Biology of Reproduction.

Endogenous production of hyaluronan, PRG4, and cytokines is sensitive to cyclic loading in synoviocytes

E. Blaber, T. Schmidt, Douglas K. Brubaker, 2022, bioRxiv.

Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation.

Samantha Dale Strasser, D. Lauffenburger, S. Gygi, 2019, Cell systems.

A framework for translation of genomic responses from mouse models to human inflammatory disease contexts

D. Lauffenburger, E. Proctor, K. Haigis, 2018, bioRxiv.

Translating preclinical models to humans

D. Lauffenburger, Douglas K. Brubaker, 2020, Science.

Latent Interacting Variable-Effects Modeling of Gut Microbiome Multi-Omics in Inflammatory Bowel Disease

Douglas K. Brubaker, Javier. E. Munoz, Javier Munoz, 2022, bioRxiv.

Latent Interacting Variable-Effects Modeling of Gut Microbiome Multi-Omics in Inflammatory Bowel Disease

Douglas K. Brubaker, Javier. E. Munoz, 2022, bioRxiv.

Brazil's doomed environmental licensing

Douglas K. Brubaker, 2021, Science.

Science Magazine

Douglas K. Brubaker, 2010 .

Tissue-Specific Oncogenic Activity of KRASA146T.

Samantha Dale Strasser, Brian A. Joughin, D. Lauffenburger, 2019, Cancer discovery.

Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms

D. Lauffenburger, L. Griffith, Douglas K. Brubaker, 2020, Antimicrobial Agents and Chemotherapy.

Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis

Samantha Dale Strasser, D. Lauffenburger, J. Kissil, 2018, Science Signaling.

Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3

D. Lauffenburger, R. Coffey, A. Starchenko, 2021, Integrative biology : quantitative biosciences from nano to macro.

TRANS-OMIC KNOWLEDGE TRANSFER MODELING INFERS GUT MICROBIOME BIOMARKERS OF ANTI-TNF RESISTANCE IN ULCERATIVE COLITIS.

Douglas K. Brubaker, R. Ran, Alan Trinh, 2022, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.

Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation

D. Lauffenburger, K. Haigis, A. Starchenko, 2021, iScience.

C. difficile-associated antibiotics prime the host for infection by a microbiome-independent mechanism

D. Lauffenburger, L. Griffith, Douglas K. Brubaker, 2019, bioRxiv.

Computational Interspecies Translation Between Alzheimer’s Disease Mouse Models and Human Subjects Identifies Innate Immune Complement, TYROBP, and TAM Receptor Agonist Signatures, Distinct From Influences of Aging

D. Lauffenburger, B. Hyman, M. J. Carroll, 2021, Frontiers in Neuroscience.

A dynamical systems model of progesterone receptor interactions with inflammation in human parturition

Mark R. Chance, Alethea Barbaro, Sam Mesiano, 2016, BMC Systems Biology.

Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

D. Lauffenburger, L. Leon, M. Yaffe, 2020, Journal of thrombosis and haemostasis : JTH.

Coagulopathy signature precedes and predicts severity of end-organ heat stroke pathology in a mouse model

D. Lauffenburger, L. Leon, M. Yaffe, 2019 .

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

Paige N. Vega, Elizabeth A. Scoville, Lori A. Coburn, 2020, Science Signaling.

An Inter-Species Translation Model Implicates Integrin Signaling in Infliximab-Resistant Colonic Crohn’s Disease

Paige N. Vega, Elizabeth A. Scoville, Lori A. Coburn, 2019 .

Frequent Subgraph Mining of Personalized Signaling Pathway Networks Groups Patients with Frequently Dysregulated Disease Pathways and Predicts Prognosis

Gürkan Bebek, Tim A. D. Henderson, Arda Durmaz, 2017, PSB.

Enhanced annotation of CD45RA to distinguish T cell subsets in single-cell RNA-seq via machine learning

Douglas K. Brubaker, Ran Ran, 2023, bioRxiv.

Computational translation of genomic responses from experimental model systems to humans

Douglas A Lauffenburger, Douglas K Brubaker, Elizabeth A Proctor, 2019, PLoS Comput. Biol..

Detailed survey of an in vitro intestinal epithelium model by single-cell transcriptomics

Leopold N. Green, Douglas K. Brubaker, R. Ran, 2023, bioRxiv.

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling

D. Lauffenburger, J. Baeten, E. Katabira, 2023, Cell reports.

Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis

Samantha Dale Strasser, D. Lauffenburger, J. Kissil, 2018, Science Signaling.

Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth.

M. Chance, B. Jacobsson, L. Muglia, 2016, Human molecular genetics.