Albert S. Ren

发表

Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.

Brian M. Smith, F. Menzaghi, P. Dosa, 2008, Journal of medicinal chemistry.

Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile.

F. Du, C. Sage, Albert S. Ren, 2012, Bioorganic & medicinal chemistry letters.

A new family of H3 receptor antagonists based on the natural product Conessine.

V. Santora, J. Knudsen, C. Sage, 2008, Bioorganic & medicinal chemistry letters.

Novel H3 receptor antagonists with improved pharmacokinetic profiles.

V. Santora, John Covel, Albert S. Ren, 2008, Bioorganic & medicinal chemistry letters.

Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays.

C. Sage, Albert S. Ren, Michael E. Morgan, 2019, Bioorganic & medicinal chemistry letters.

Novel (R)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,n]naphthyridines as potent and selective agonists of the 5-HT2C receptor.

Albert S. Ren, K. Whelan, A. Grottick, 2021, Bioorganic & medicinal chemistry letters.

Tetrahydroquinoline-based tricyclic amines as potent and selective agonists of the 5-HT2C receptor.

C. Sage, Albert S. Ren, K. Whelan, 2016, Bioorganic & medicinal chemistry letters.

Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

C. Sage, B. Fioravanti, Albert S. Ren, 2011, Bioorganic & medicinal chemistry letters.

Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119.

William Thomsen, B. Fioravanti, Albert S. Ren, 2008, Journal of medicinal chemistry.

Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.

Brian M. Smith, F. Menzaghi, P. Dosa, 2008, Journal of medicinal chemistry.