C. Saris

发表

Interleukin‐3 signals through multiple isoforms of Stat5.

H. Erdjument-Bromage, P. Tempst, C. Schindler, 1995, The EMBO journal.

Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza

J. Schwab, A. Scheffold, C. Hunter, 2014, PLoS pathogens.

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection.

T. Mak, R. Faggioni, H. Nishina, 2001, Immunity.

The WSX-1 pathway restrains intestinal T-cell immunity.

A. Vella, C. Saris, J. McAleer, 2011, International immunology.

Positive and Negative Regulation of the IL-27 Receptor during Lymphoid Cell Activation1

C. Hunter, F. D. de Sauvage, A. Villarino, 2005, The Journal of Immunology.

IL-27 Receptor Signaling Regulates CD4+ T Cell Chemotactic Responses during Infection

C. Hunter, E. Riley, A. Villegas-Méndez, 2013, The Journal of Immunology.

Impaired interleukin-3 response in Pim-1-deficient bone marrow-derived mast cells.

P. Laird, A. Berns, J. Domen, 1993, Blood.

Analysis of Pim-1 function in mutant mice.

P. Laird, A. Berns, J. Domen, 1993, Leukemia.

Macrophage‐colony stimulating factor is required for the production of neutrophil‐promoting activity by mouse embryo fibroblasts deficient in G‐CSF and GM‐CSF

C. Begley, C. Begley, A. Burgess, 2007, Journal of leukocyte biology.

Hydroxylamine cleavage of proteins in polyacrylamide gels.

B. Jenks, C. Saris, H. Bloemers, 1983, Analytical biochemistry.

The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity1

G. Wu, C. Hunter, F. D. de Sauvage, 2004, The Journal of Immunology.

Ectopic overexpression of c-mpl by retroviral-mediated gene transfer suppressed megakaryopoiesis but enhanced erythropoiesis in mice.

D. Lacey, R. Hawley, C. Saris, 1999, Experimental hematology.

IL-27 inhibits hyperglycemia and pancreatic islet inflammation induced by streptozotocin in mice.

K. Node, C. Saris, H. Yoshida, 2011, The American journal of pathology.

G-Protein-Coupled Receptor 35 Is a Target of the Asthma Drugs Cromolyn Disodium and Nedocromil Sodium

J. Reagan, C. Saris, J. Whoriskey, 2010, Pharmacology.

Structure of glycosylated and unglycosylated gag and gag-pol precursor proteins of Moloney murine leukemia virus

R. Liskamp, C. Saris, H. Bloemers, 1983, Journal of virology.

IL-27 Receptor Signalling Restricts the Formation of Pathogenic, Terminally Differentiated Th1 Cells during Malaria Infection by Repressing IL-12 Dependent Signals

C. Hunter, E. Riley, A. Villegas-Méndez, 2013, PLoS pathogens.

WSX-1 Signalling Inhibits CD4+ T Cell Migration to the Liver during Malaria Infection by Repressing Chemokine-Independent Pathways

E. Riley, A. Villegas-Méndez, K. Couper, 2013, PloS one.

A Novel Role for IL-27 in Mediating the Survival of Activated Mouse CD4 T Lymphocytes

Gisen Kim, M. Kronenberg, H. Cheroutre, 2013, The Journal of Immunology.

This information is current as Lymphocytes Survival of Activated Mouse CD 4 T A Novel Role for IL-27 in Mediating the Cheroutre and Mitchell Kronenberg

Gisen Kim, M. Kronenberg, H. Cheroutre, 2013 .

The tsA58 simian virus 40 large tumor antigen disrupts megakaryocyte differentiation in transgenic mice.

W. Zhou, M. Robinson, C. Saris, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Interleukin 27 inhibits atherosclerosis via immunoregulation of macrophages in mice.

K. Node, N. Ide, C. Saris, 2013, American journal of physiology. Heart and circulatory physiology.

cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I).

P. D’Eustachio, T. Hunter, D. Noonan, 1987, The Journal of biological chemistry.

Essential Role for IL-27 Receptor Signaling in Prevention of Th1-Mediated Immunopathology during Malaria Infection

C. Hunter, E. Riley, K. Couper, 2010, The Journal of Immunology.

Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5' noncoding exons.

T. Hunter, J. Meisenhelder, G. Moffat, 1996, Biochimica et biophysica acta.

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

Christopher A Hunter, Matthias Ernst, C. Hunter, 2007, Nature Immunology.

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27–stimulated T cells

Mohamed El-behi, C. Saris, Hongmei Li, 2007, Nature Immunology.

Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitors.

Matthew R. Lee, A. Tasker, Bin Wu, 2010, Journal of medicinal chemistry.

Identification of triazolopyridazinones as potent p38α inhibitors.

S. Chmait, B. Herberich, Matthew R. Lee, 2012, Bioorganic & medicinal chemistry letters.

Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.

S. Chmait, K. Miner, Matthew R. Lee, 2010, Bioorganic & medicinal chemistry letters.

Nucleotide sequence of a viral RNA fragment that binds to eukaryotic ribosomes

P. Kaesberg, D. S. Shih, R. Dasgupta, 1975, Nature.

Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase.

Christopher Mohr, Lisa Sherman, S. Chmait, 2010, Journal of medicinal chemistry.

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats

T. Hunter, J. Glenney, C. Saris, 1986, Cell.

Primary structure of bovine calpactin I heavy chain (p36), a major cellular substrate for retroviral protein-tyrosine kinases: homology with the human phospholipase A2 inhibitor lipocortin.

T. Hunter, D. Noonan, J. Glenney, 1986, Biochemistry.

The IL-27 Receptor Chain WSX-1 Differentially Regulates Antibacterial Immunity and Survival during Experimental Tuberculosis 1

T. Mak, S. Ehlers, T. Yoshimoto, 2005, The Journal of Immunology.

The pim‐1 oncogene encodes two related protein‐serine/threonine kinases by alternative initiation at AUG and CUG.

A. Berns, A. Berns, J. Domen, 1991, The EMBO journal.

Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

A. Berns, M. Lohuizen, J. Domen, 1989, Cell.

Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)

S. Lowe, T. Mak, I. Sarosi, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoeitin/MGDF in megakaryocyte development

S. Orkin, R. Shivdasani, C. Saris, 1995, Cell.

Megakaryocyte growth and development factor and interleukin-3 induce patterns of protein-tyrosine phosphorylation that correlate with dominant differentiation over proliferation of mpl-transfected 32D cells.

M. Xia, C. Saris, G. Elliott, 1995, Blood.

Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice.

D. Lacey, R. Hawley, M. Xia, 1995, Blood.

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI

M. C. Hu, D. Wen, M. Hu, 1994, Cell.

A role for IL-27p28 as an antagonist of gp130-mediated signaling

C. Fielding, S. Rose-John, C. Hunter, 2010, Nature Immunology.

Interleukin-27 Receptor Limits Atherosclerosis in Ldlr−/− Mice

K. Ley, Gisen Kim, M. Kronenberg, 2012, Circulation research.

Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system

L. Hennighausen, A. Yoshimura, C. Tato, 2006, Nature Immunology.

IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD.

C. Hunter, D. Artis, A. Villarino, 2008, International immunology.

Structure and chromosome assignment of the murine p36 (calpactin I heavy chain) gene.

P. D’Eustachio, T. Hunter, D. Chaplin, 1990, Biochemistry.

Cells and Murine Experimental Th17 and IL-10 in the Suppression of Human , β Immunoregulatory Effects of IL-27, IFN- Independent and Interdependent

C. Saris, D. Fitzgerald, Guang-Xian Zhang, 2014 .

Independent and Interdependent Immunoregulatory Effects of IL-27, IFN-β, and IL-10 in the Suppression of Human Th17 Cells and Murine Experimental Autoimmune Encephalomyelitis

C. Saris, D. Fitzgerald, Guang-Xian Zhang, 2013, The Journal of Immunology.

Immunopathology during Malaria Infection in Prevention of Th1-Mediated Essential Role for IL-27 Receptor Signaling

C. Hunter, E. Riley, E. Findlay, 2010 .

Immunopathology during Malaria Infection in Prevention of Th 1-Mediated Essential Role for IL-27 Receptor Signaling Couper

C. Hunter, E. Riley, E. Findlay, 2010 .

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection.

T. Mak, R. Kastelein, C. Hunter, 2003, Immunity.

IL-27 Limits IL-2 Production during Th1 Differentiation1

R. Kastelein, C. Hunter, F. D. de Sauvage, 2006, The Journal of Immunology.

Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27.

W. Alexander, D. Hilton, B. Jenkins, 2007, Blood.

Megak . aryocyte Growth and Development Factor and Interleukin-3 Induce Patterns of Protein-Tyrosine Phosphorylation That Correlate With Dominant Differentiation Over Proliferation of mpl-Transfected 32 D Cells

M. Xia, C. Saris, G. Elliott, 2000 .

IL-27 Regulates Homeostasis of the Intestinal CD4+ Effector T Cell Pool and Limits Intestinal Inflammation in a Murine Model of Colitis1

C. Hunter, D. Artis, A. Troy, 2009, The Journal of Immunology.

Cutting Edge: Early IL-4 Production Governs the Requirement for IL-27-WSX-1 Signaling in the Development of Protective Th1 Cytokine Responses following Leishmania major Infection1

C. Hunter, D. Artis, P. Scott, 2004, The Journal of Immunology.

3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase.

R. Syed, Matthew R. Lee, A. Tasker, 2008, Journal of medicinal chemistry.

Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.

S. Chmait, K. Miner, Matthew R. Lee, 2009, Bioorganic & medicinal chemistry letters.

Characterization of the Stat5 Protease*

C. Schindler, M. Jarosinski, C. Saris, 1999, The Journal of Biological Chemistry.

IL-27 Receptor Signaling Regulates Memory CD4+ T Cell Populations and Suppresses Rapid Inflammatory Responses during Secondary Malaria Infection

E. Riley, A. Villegas-Méndez, K. Couper, 2013, Infection and Immunity.

SOCS 3 regulates CD 8 T cell proliferation by inhibition of IL-6 and IL-27

W. Alexander, D. Hilton, B. Jenkins, 2007 .

Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase.

S. Chmait, B. Herberich, Matthew R. Lee, 2010, Journal of medicinal chemistry.

IL-27 Regulates Homeostasis of the Intestinal CD4+ Effector T Cell Pool and Limits Intestinal Inflammation in a Murine Model of Colitis1

C. Hunter, D. Artis, A. Troy, 2009, The Journal of Immunology.

IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD.

Jelena S. Bezbradica, C. Hunter, D. Artis, 2008, International immunology.

LymphocytesSurvival of Activated Mouse CD4 T A Novel Role for IL-27 in Mediating the

Gisen Kim, M. Kronenberg, H. Cheroutre, 2013 .

This information is current as Lymphocytes Survival of Activated Mouse CD 4 T A Novel Role for IL-27 in Mediating the Cheroutre and Mitchell Kronenberg

Gisen Kim, M. Kronenberg, H. Cheroutre, 2013 .

This information is current as Lymphocytes Survival of Activated Mouse CD 4 T A Novel Role for IL-27 in Mediating the Cheroutre and Mitchell Kronenberg

Gisen Kim, M. Kronenberg, H. Cheroutre, 2013 .